Bo Huang

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. pmc Super-resolution fluorescence microscopy
    Bo Huang
    Howard Hughes Medical Institute, Harvard University, Cambridge, MA 02138, USA
    Annu Rev Biochem 78:993-1016. 2009
  2. pmc Three-dimensional super-resolution imaging by stochastic optical reconstruction microscopy
    Bo Huang
    Howard Hughes Medical Institute, Harvard University, Cambridge, MA 02138, USA
    Science 319:810-3. 2008
  3. pmc Super-resolution microscopy by nanoscale localization of photo-switchable fluorescent probes
    Mark Bates
    School of Engineering and Applied Sciences, Cambridge, MA 02138, United States, USA
    Curr Opin Chem Biol 12:505-14. 2008
  4. pmc Super-resolution fluorescence imaging of organelles in live cells with photoswitchable membrane probes
    Sang Hee Shim
    Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA 02138, USA
    Proc Natl Acad Sci U S A 109:13978-83. 2012
  5. pmc Coupling between clathrin-dependent endocytic budding and F-BAR-dependent tubulation in a cell-free system
    Min Wu
    Howard Hughes Medical Institute, Yale University School of Medicine, New Haven, CT 06520, USA
    Nat Cell Biol 12:902-8. 2010
  6. pmc Superresolution imaging of chemical synapses in the brain
    Adish Dani
    Howard Hughes Medical Institute, Harvard University, Cambridge, MA 02138, USA
    Neuron 68:843-56. 2010
  7. pmc Multicolor super-resolution imaging with photo-switchable fluorescent probes
    Mark Bates
    School of Engineering and Applied Sciences, Harvard University, Cambridge, MA 02138, USA
    Science 317:1749-53. 2007
  8. pmc Whole-cell 3D STORM reveals interactions between cellular structures with nanometer-scale resolution
    Bo Huang
    Howard Hughes Medical Institute, Harvard University, 12 Oxford St Cambridge, Massachusetts 02138, USA
    Nat Methods 5:1047-52. 2008

Collaborators

  • Min Wu
  • Adish Dani
  • Mark Bates
  • Xiaowei Zhuang
  • Sang Hee Shim
  • Guisheng Zhong
  • Guo Qiang Bi
  • Xun Wang
  • Joshua C Vaughan
  • Cheng Xu
  • Chenglong Xia
  • Hazen P Babcock
  • Graham T Dempsey

Detail Information

Publications8

  1. pmc Super-resolution fluorescence microscopy
    Bo Huang
    Howard Hughes Medical Institute, Harvard University, Cambridge, MA 02138, USA
    Annu Rev Biochem 78:993-1016. 2009
    ..It is anticipated that super-resolution fluorescence microscopy will become a widely used tool for cell and tissue imaging to provide previously unobserved details of biological structures and processes...
  2. pmc Three-dimensional super-resolution imaging by stochastic optical reconstruction microscopy
    Bo Huang
    Howard Hughes Medical Institute, Harvard University, Cambridge, MA 02138, USA
    Science 319:810-3. 2008
    ..This development allowed us to resolve the 3D morphology of nanoscopic cellular structures...
  3. pmc Super-resolution microscopy by nanoscale localization of photo-switchable fluorescent probes
    Mark Bates
    School of Engineering and Applied Sciences, Cambridge, MA 02138, United States, USA
    Curr Opin Chem Biol 12:505-14. 2008
    ....
  4. pmc Super-resolution fluorescence imaging of organelles in live cells with photoswitchable membrane probes
    Sang Hee Shim
    Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA 02138, USA
    Proc Natl Acad Sci U S A 109:13978-83. 2012
    ..We observed previously obscured details of morphological dynamics of mitochondrial fusion/fission and ER remodeling, as well as heterogeneous membrane diffusivity on neuronal processes...
  5. pmc Coupling between clathrin-dependent endocytic budding and F-BAR-dependent tubulation in a cell-free system
    Min Wu
    Howard Hughes Medical Institute, Yale University School of Medicine, New Haven, CT 06520, USA
    Nat Cell Biol 12:902-8. 2010
    ..They also show that clathrin spatially directs plasma membrane invaginations that lead to the generation of endocytic vesicles larger than those enclosed by the coat...
  6. pmc Superresolution imaging of chemical synapses in the brain
    Adish Dani
    Howard Hughes Medical Institute, Harvard University, Cambridge, MA 02138, USA
    Neuron 68:843-56. 2010
    ..Combination with optogenetics further allowed molecular events associated with synaptic plasticity to be resolved at the single-synapse level...
  7. pmc Multicolor super-resolution imaging with photo-switchable fluorescent probes
    Mark Bates
    School of Engineering and Applied Sciences, Harvard University, Cambridge, MA 02138, USA
    Science 317:1749-53. 2007
    ..Using this approach, we demonstrate multicolor imaging of DNA model samples and mammalian cells with 20- to 30-nanometer resolution. This technique will facilitate direct visualization of molecular interactions at the nanometer scale...
  8. pmc Whole-cell 3D STORM reveals interactions between cellular structures with nanometer-scale resolution
    Bo Huang
    Howard Hughes Medical Institute, Harvard University, 12 Oxford St Cambridge, Massachusetts 02138, USA
    Nat Methods 5:1047-52. 2008
    ..The 3D STORM images resolved mitochondrial morphologies as well as mitochondria-microtubule contacts that were obscured in conventional fluorescence images...