Frank B Hu

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. ncbi Inflammatory markers and risk of developing type 2 diabetes in women
    Frank B Hu
    Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts, USA
    Diabetes 53:693-700. 2004
  2. ncbi Increased mortality risk in women with depression and diabetes mellitus
    An Pan
    Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
    Arch Gen Psychiatry 68:42-50. 2011
  3. ncbi Obesity genotype score and cardiovascular risk in women with type 2 diabetes mellitus
    Meian He
    Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
    Arterioscler Thromb Vasc Biol 30:327-32. 2010
  4. ncbi Fruit and vegetable intake and risk of major chronic disease
    Hsin-Chia Hung
    Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
    J Natl Cancer Inst 96:1577-84. 2004
  5. ncbi Major dietary patterns are related to plasma concentrations of markers of inflammation and endothelial dysfunction
    Esther Lopez-Garcia
    Department of Nutrition and the Division of Preventive Medicine, Harvard Medical School, Boston, USA
    Am J Clin Nutr 80:1029-35. 2004
  6. ncbi Joint effects of common genetic variants on the risk for type 2 diabetes in U.S. men and women of European ancestry
    Marilyn C Cornelis
    Harvard School of Public Health, Channing Laboratory, Boston, MA 02115, USA
    Ann Intern Med 150:541-50. 2009
  7. ncbi Prospective study of major dietary patterns and stroke risk in women
    Teresa T Fung
    Department of Nutrition, Simmons College, 300 The Fenway, Boston, MA 02115, USA
    Stroke 35:2014-9. 2004
  8. ncbi Regular consumption of nuts is associated with a lower risk of cardiovascular disease in women with type 2 diabetes
    Tricia Y Li
    Department of Nutrition, and 4Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
    J Nutr 139:1333-8. 2009
  9. ncbi Consumption of trans fatty acids is related to plasma biomarkers of inflammation and endothelial dysfunction
    Esther Lopez-Garcia
    Department of Nutrition, Harvard School of Public Health, Boston, MA, USA
    J Nutr 135:562-6. 2005
  10. ncbi Blood concentrations of individual long-chain n-3 fatty acids and risk of nonfatal myocardial infarction
    Qi Sun
    Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
    Am J Clin Nutr 88:216-23. 2008

Detail Information

Publications121 found, 100 shown here

  1. ncbi Inflammatory markers and risk of developing type 2 diabetes in women
    Frank B Hu
    Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts, USA
    Diabetes 53:693-700. 2004
    ..001). These data support the role of inflammation in the pathogenesis of type 2 diabetes. Elevated CRP levels are a strong independent predictor of type 2 diabetes and may mediate associations of TNF-alphaR2 and IL-6 with type 2 diabetes...
  2. ncbi Increased mortality risk in women with depression and diabetes mellitus
    An Pan
    Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
    Arch Gen Psychiatry 68:42-50. 2011
    ..Depression and diabetes mellitus have been associated with an increased risk of all-cause and cardiovascular disease (CVD) mortality. However, data evaluating the joint effects of these 2 conditions on mortality are sparse...
  3. ncbi Obesity genotype score and cardiovascular risk in women with type 2 diabetes mellitus
    Meian He
    Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
    Arterioscler Thromb Vasc Biol 30:327-32. 2010
    ..To investigate the associations between obesity-predisposing genetic variants, cardiovascular biomarkers, and cardiovascular disease (CVD) risk in women with preexisting type 2 diabetes mellitus...
  4. ncbi Fruit and vegetable intake and risk of major chronic disease
    Hsin-Chia Hung
    Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
    J Natl Cancer Inst 96:1577-84. 2004
    ..The benefits appeared to be primarily for cardiovascular disease and not for cancer...
  5. ncbi Major dietary patterns are related to plasma concentrations of markers of inflammation and endothelial dysfunction
    Esther Lopez-Garcia
    Department of Nutrition and the Division of Preventive Medicine, Harvard Medical School, Boston, USA
    Am J Clin Nutr 80:1029-35. 2004
    ..Endothelial dysfunction is one of the mechanisms linking diet and the risk of cardiovascular disease...
  6. ncbi Joint effects of common genetic variants on the risk for type 2 diabetes in U.S. men and women of European ancestry
    Marilyn C Cornelis
    Harvard School of Public Health, Channing Laboratory, Boston, MA 02115, USA
    Ann Intern Med 150:541-50. 2009
    ..Genome-wide association studies have identified novel type 2 diabetes loci, each of which has a modest impact on risk...
  7. ncbi Prospective study of major dietary patterns and stroke risk in women
    Teresa T Fung
    Department of Nutrition, Simmons College, 300 The Fenway, Boston, MA 02115, USA
    Stroke 35:2014-9. 2004
    ..Many foods have been suggested to influence the risk of stroke. However, no previous studies have examined the relationship between overall dietary patterns and risk of stroke...
  8. ncbi Regular consumption of nuts is associated with a lower risk of cardiovascular disease in women with type 2 diabetes
    Tricia Y Li
    Department of Nutrition, and 4Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
    J Nutr 139:1333-8. 2009
    ..These data suggest that frequent nut and peanut butter consumption is associated with a significantly lower CVD risk in women with type 2 diabetes...
  9. ncbi Consumption of trans fatty acids is related to plasma biomarkers of inflammation and endothelial dysfunction
    Esther Lopez-Garcia
    Department of Nutrition, Harvard School of Public Health, Boston, MA, USA
    J Nutr 135:562-6. 2005
    ....
  10. ncbi Blood concentrations of individual long-chain n-3 fatty acids and risk of nonfatal myocardial infarction
    Qi Sun
    Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
    Am J Clin Nutr 88:216-23. 2008
    ..Whereas dietary intake of long-chain n-3 fatty acids has been associated with risk of nonfatal myocardial infarction (MI), few studies have examined the relation for blood concentrations...
  11. ncbi Changes in caffeine intake and long-term weight change in men and women
    Esther Lopez-Garcia
    Department of Nutrition, Harvard School of Public Health, Cambridge, MA, USA
    Am J Clin Nutr 83:674-80. 2006
    ..001). CONCLUSION: Increases in caffeine intake may lead to a small reduction in long-term weight gain...
  12. ncbi Bidirectional association between depression and type 2 diabetes mellitus in women
    An Pan
    Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
    Arch Intern Med 170:1884-91. 2010
    ..Although it has been hypothesized that the diabetes-depression relation is bidirectional, few studies have addressed this hypothesis in a prospective setting...
  13. ncbi Red meat consumption and mortality: results from 2 prospective cohort studies
    An Pan
    Departments of Nutrition and Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
    Arch Intern Med 172:555-63. 2012
    ..Red meat consumption has been associated with an increased risk of chronic diseases. However, its relationship with mortality remains uncertain...
  14. ncbi Sweetened beverage consumption and risk of coronary heart disease in women
    Teresa T Fung
    Department of Nutrition, Simmons College, Boston, MA 02115, USA
    Am J Clin Nutr 89:1037-42. 2009
    ..Previous studies have linked full-calorie sugar-sweetened beverages (SSBs) with greater weight gain and an increased risk of type 2 diabetes...
  15. ncbi Magnesium intake and plasma concentrations of markers of systemic inflammation and endothelial dysfunction in women
    Yiqing Song
    Division of Preventive Medicine and Epidemiology, Harvard School of Public Health, Boston, MA, USA
    Am J Clin Nutr 85:1068-74. 2007
    ..Relations between magnesium intake and systemic inflammation and endothelial dysfunction are not well established...
  16. ncbi Adherence to the Mediterranean dietary pattern is positively associated with plasma adiponectin concentrations in diabetic women
    Christos S Mantzoros
    Division of Endocrinology, Diabetes, and Metabolism, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA and Nutrition, Harvard School of Public Health, Boston, MA, USA
    Am J Clin Nutr 84:328-35. 2006
    ..Close adherence to a Mediterranean-type diet is associated with higher adiponectin concentrations...
  17. ncbi Physical activity in relation to cardiovascular disease and total mortality among men with type 2 diabetes
    Mihaela Tanasescu
    Department of Nutrition, Harvard School of Public Health, Boston, Mass, USA
    Circulation 107:2435-9. 2003
    ..CVD risk and mortality are increased in type 2 diabetes. Few epidemiological studies have investigated the effect of physical activity on these outcomes among type 2 diabetics...
  18. ncbi Caffeinated and caffeine-free beverages and risk of type 2 diabetes
    Shilpa N Bhupathiraju
    Departments of Nutrition and Epidemiology, Harvard School of Public Health, Boston, MA Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA
    Am J Clin Nutr 97:155-66. 2013
    ..Consumption of caffeinated beverages such as coffee and tea has been associated with a lower risk of type 2 diabetes (T2D). Paradoxically, short-term metabolic studies have shown that caffeine impairs postprandial glycemic control...
  19. ncbi Consumption of (n-3) fatty acids is related to plasma biomarkers of inflammation and endothelial activation in women
    Esther Lopez-Garcia
    Department of Nutrition, Harvard School of Public Health, Harvard Medical School, USA
    J Nutr 134:1806-11. 2004
    ....
  20. ncbi Vitamin C and risk of coronary heart disease in women
    Stavroula K Osganian
    Department of Medicine, Children s Hospital, Boston, Massachusetts, USA
    J Am Coll Cardiol 42:246-52. 2003
    ..Our objective was to prospectively examine the relation between vitamin C intake and risk of coronary heart disease (CHD) in women...
  21. ncbi Whole-grain, bran, and cereal fiber intakes and markers of systemic inflammation in diabetic women
    Lu Qi
    Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
    Diabetes Care 29:207-11. 2006
    ..To evaluate the dietary predictors for the markers of systemic inflammation and endothelial dysfunction in patients with type 2 diabetes...
  22. ncbi Low-carbohydrate-diet score and the risk of coronary heart disease in women
    Thomas L Halton
    Departments of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
    N Engl J Med 355:1991-2002. 2006
    ..When vegetable sources of fat and protein are chosen, these diets may moderately reduce the risk of coronary heart disease...
  23. ncbi Relation between changes in intakes of dietary fiber and grain products and changes in weight and development of obesity among middle-aged women
    Simin Liu
    Division of Preventive Medicine and the Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02215, USA
    Am J Clin Nutr 78:920-7. 2003
    ..Although increased consumption of dietary fiber and grain products is widely recommended to maintain healthy body weight, little is known about the relation of whole grains to body weight and long-term weight changes...
  24. ncbi Circulating levels of endothelial adhesion molecules and risk of diabetes in an ethnically diverse cohort of women
    Yiqing Song
    Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
    Diabetes 56:1898-904. 2007
    ..S. postmenopausal women, implicating an etiological role of endothelial dysfunction in the pathogenesis of type 2 diabetes...
  25. ncbi Genetic predisposition, Western dietary pattern, and the risk of type 2 diabetes in men
    Lu Qi
    Department of Nutrition, Harvard School of Public Health, Boston, MA, USA
    Am J Clin Nutr 89:1453-8. 2009
    ..A widely held hypothesis is that interactions between genetic predisposition and Western-type lifestyle contribute to the epidemic of type 2 diabetes (T2D). No study has tested this hypothesis...
  26. ncbi Associations of the apolipoprotein A1/C3/A4/A5 gene cluster with triglyceride and HDL cholesterol levels in women with type 2 diabetes
    Lu Qi
    Department of Nutrition, Harvard School of Public Health, 665 Huntington Ave, Boston, MA 02115, United States
    Atherosclerosis 192:204-10. 2007
    ..006), whereas APOA4 +347T/A showed significant associations with lower levels of HDL-C (P=0.017). Our results indicate that the variability in APOA1/C3/A4/A5 gene cluster may affect TG and HDL levels in women with type 2 diabetes...
  27. ncbi Adiposity as compared with physical activity in predicting mortality among women
    Frank B Hu
    Department of Nutrition, Harvard School of Public Health, Boston, Copyright 2004 Massachusetts Medical Society USA
    N Engl J Med 351:2694-703. 2004
    ..Whether higher levels of physical activity can counteract the elevated risk of death associated with adiposity is controversial...
  28. ncbi Single nucleotide polymorphisms at the adiponectin locus and risk of coronary heart disease in men and women
    Tobias Pischon
    Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts, USA
    Obesity (Silver Spring) 15:2051-60. 2007
    ..The objective was to examine the association of 5 common single nucleotide polymorphisms (SNPs) at the adiponectin locus with risk of coronary heart disease (CHD) in men and women...
  29. ncbi Sugar-sweetened beverages and genetic risk of obesity
    Qibin Qi
    Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
    N Engl J Med 367:1387-96. 2012
    ..Temporal increases in the consumption of sugar-sweetened beverages have paralleled the rise in obesity prevalence, but whether the intake of such beverages interacts with the genetic predisposition to adiposity is unknown...
  30. ncbi Plain-water intake and risk of type 2 diabetes in young and middle-aged women
    An Pan
    Department of Nutrition, Harvard School of Public Health, 655 Huntington Avenue, Boston, MA 02115, USA
    Am J Clin Nutr 95:1454-60. 2012
    ..The replacement of caloric beverages such as sugar-sweetened beverages (SSBs) and fruit juices with noncaloric beverages such as plain water has been recommended for diabetes prevention...
  31. ncbi Alternative dietary indices both strongly predict risk of chronic disease
    Stephanie E Chiuve
    Department of Medicine, Harvard Medical School, Boston, MA, USA
    J Nutr 142:1009-18. 2012
    ..However, the AHEI-2010, which included additional dietary information, was more strongly associated with chronic disease risk, particularly CHD and diabetes...
  32. ncbi Joint association of glycemic load and alcohol intake with type 2 diabetes incidence in women
    Rania A Mekary
    Department of Nutrition, Harvard School of Public Health, Boston, MA, USA
    Am J Clin Nutr 94:1525-32. 2011
    ..Little is known about the joint association between glycemic index (GI), glycemic load (GL), and alcohol intake with type 2 diabetes (T2D)...
  33. ncbi Risk factors for mortality in the nurses' health study: a competing risks analysis
    Heather J Baer
    Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
    Am J Epidemiol 173:319-29. 2011
    ..In the future, this new model may be used to identify individuals at increased risk of mortality...
  34. ncbi Major dietary protein sources and risk of coronary heart disease in women
    Adam M Bernstein
    Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
    Circulation 122:876-83. 2010
    ..Our objective was to examine the relation between foods that are major dietary protein sources and incident CHD...
  35. ncbi Associations of diet with albuminuria and kidney function decline
    Julie Lin
    Renal Division, Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, 75 Francis Street, Boston, MA 02115, USA
    Clin J Am Soc Nephrol 5:836-43. 2010
    ..Sparse longitudinal data exist on how diet influences microalbuminuria and estimated GFR (eGFR) decline in people with well-preserved kidney function...
  36. ncbi Genome-wide association study identifies variants at the IL18-BCO2 locus associated with interleukin-18 levels
    Meian He
    Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
    Arterioscler Thromb Vasc Biol 30:885-90. 2010
    ..We sought to identify the common genetic variants associated with IL-18 levels...
  37. ncbi Dietary, lifestyle, and clinical predictors of lipoprotein-associated phospholipase A2 activity in individuals without coronary artery disease
    Ida J Hatoum
    Department of Nutrition and Epidemiology, Harvard School of Public Health, Boston MA, USA
    Am J Clin Nutr 91:786-93. 2010
    ..Elevated lipoprotein-associated phospholipase A(2) (Lp-PLA(2)) may be positively associated with risk of coronary artery disease, yet little is known about potentially modifiable factors related to Lp-PLA(2)...
  38. ncbi New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk
    Josee Dupuis
    Department of Biostatistics, Boston University School of Public Health, Massachusetts, USA
    Nat Genet 42:105-16. 2010
    ....
  39. ncbi A prospective study of trans fatty acids in erythrocytes and risk of coronary heart disease
    Qi Sun
    Department of Nutrition, Harvard School of Public Health, 665 Huntington Ave, Boston, MA 02115, USA
    Circulation 115:1858-65. 2007
    ..We assessed the hypothesis that higher trans fatty acid contents in erythrocytes were associated with an elevated risk of CHD in a nested case-control study among US women...
  40. ncbi Genetic polymorphisms of angiotensin-2 type 1 receptor and angiotensinogen and risk of renal dysfunction and coronary heart disease in type 2 diabetes mellitus
    Julie Lin
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
    BMC Nephrol 10:9. 2009
    ....
  41. ncbi Genome-wide association study of tanning phenotype in a population of European ancestry
    Hongmei Nan
    Channing Laboratory, Department of Medicine, Harvard Medical School, Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
    J Invest Dermatol 129:2250-7. 2009
    ..Overall, these tanning ability-related loci are similar to the hair color-related loci previously reported in the GWAS of hair color...
  42. ncbi Glycemic index, glycemic load, and cereal fiber intake and risk of type 2 diabetes in US black women
    Supriya Krishnan
    Slone Epidemiology Center, Boston, MA 02215, USA
    Arch Intern Med 167:2304-9. 2007
    ..Previous studies of carbohydrate quality and risk of type 2 diabetes mellitus have yielded inconsistent findings. Because diet is in part culturally determined, a study of dietary factors in US black women is of interest...
  43. ncbi Soluble intercellular adhesion molecules, soluble vascular cell adhesion molecules, and risk of coronary heart disease
    Iris Shai
    Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA
    Obesity (Silver Spring) 14:2099-106. 2006
    ....
  44. ncbi Interplay between different polyunsaturated fatty acids and risk of coronary heart disease in men
    Dariush Mozaffarian
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, Mass, USA
    Circulation 111:157-64. 2005
    ..Additionally, seafood-based, long-chain n-3 PUFAs may modify the effects of plant-based, intermediate-chain n-3 PUFAs. However, the interactions of these PUFAs in relation to CHD risk are not well established...
  45. ncbi Carbohydrate intake, glycemic index, glycemic load, and dietary fiber in relation to risk of stroke in women
    Kyungwon Oh
    Department of Nutrition, Harvard School of Public Health, 665 Huntington Avenue, Boston, MA 02115, USA
    Am J Epidemiol 161:161-9. 2005
    ..In addition, high consumption of cereal fiber was associated with lower risk of total and hemorrhagic stroke...
  46. ncbi Interactions between the -514C->T polymorphism of the hepatic lipase gene and lifestyle factors in relation to HDL concentrations among US diabetic men
    Cuilin Zhang
    Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
    Am J Clin Nutr 81:1429-35. 2005
    ..A common polymorphism (-514C-->T) of the hepatic lipase gene (LIPC), which accounts for up to 30% of the variation in hepatic lipase activity, has been associated with low hepatic lipase activity and high HDL-cholesterol concentrations...
  47. ncbi Dietary fat intake and cognitive decline in women with type 2 diabetes
    ELIZABETH E DEVORE
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, Boston, Massachusetts, USA
    Diabetes Care 32:635-40. 2009
    ..We investigated whether dietary fat, which modulates glucose and lipid metabolism, might influence cognitive decline in older adults with diabetes...
  48. ncbi Magnesium intake and risk of type 2 diabetes in men and women
    Ruy Lopez-Ridaura
    Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts 02215, USA
    Diabetes Care 27:134-40. 2004
    ..To examine the association between magnesium intake and risk of type 2 diabetes...
  49. ncbi Prospective study of the association between the proline to alanine codon 12 polymorphism in the PPARgamma gene and type 2 diabetes
    Asli Memisoglu
    Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts 02115, USA
    Diabetes Care 26:2915-7. 2003
    ..To determine whether the Pro12Ala polymorphism in the PPARgamma gene was associated with risk of type 2 diabetes in the Nurses' Health Study...
  50. ncbi Obesity as compared with physical activity in predicting risk of coronary heart disease in women
    Tricia Y Li
    Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
    Circulation 113:499-506. 2006
    ..CONCLUSIONS: Obesity and physical inactivity independently contribute to the development of CHD in women. These data underscore the importance of both maintaining a healthy weight and regular physical activity in preventing CHD...
  51. ncbi Depression and incident stroke in women
    An Pan
    Department of Nutrition and Epidemiology, Harvard School of Public Health, and Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, Boston, MA 02215, USA
    Stroke 42:2770-5. 2011
    ..Depression has been associated with an increased risk of coronary heart disease, but prospective data for the association with stroke are limited...
  52. ncbi The joint association of eating frequency and diet quality with colorectal cancer risk in the Health Professionals Follow-up Study
    Rania A Mekary
    Harvard School of Public Health, 665 Huntington Avenue, Boston, MA 02115, USA
    Am J Epidemiol 175:664-72. 2012
    ..01, P for trend = 0.01). There was an implied protective association between increased eating frequency of healthy meals and colorectal cancer risk and in men with factors associated with higher insulin sensitivity...
  53. ncbi Physical activity in relation to long-term weight maintenance after intentional weight loss in premenopausal women
    Rania A Mekary
    Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts, USA
    Obesity (Silver Spring) 18:167-74. 2010
    ..Increased PA, particularly high intensity activities, is associated with better maintenance of weight loss. The benefits of activity were greater among overweight/obese than normal weight women...
  54. ncbi Association of dietary patterns with albuminuria and kidney function decline in older white women: a subgroup analysis from the Nurses' Health Study
    Julie Lin
    Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
    Am J Kidney Dis 57:245-54. 2011
    ..Dietary patterns have been linked to such chronic diseases as cardiovascular disease, but sparse data currently are available for associations between dietary patterns and microalbuminuria or kidney function decline...
  55. ncbi Dietary patterns, meat intake, and the risk of type 2 diabetes in women
    Teresa T Fung
    Department of Nutrition, Simmons College, Boston, Mass 02115, USA
    Arch Intern Med 164:2235-40. 2004
    ..To examine the association between major dietary patterns and risk of type 2 diabetes mellitus in a cohort of women...
  56. ncbi A prospective study of soluble tumor necrosis factor-alpha receptor II (sTNF-RII) and risk of coronary heart disease among women with type 2 diabetes
    Iris Shai
    Department of Epidemiology, Harvard School of Public Health, 677 Huntington Avenue, Boston, MA 02115, USA
    Diabetes Care 28:1376-82. 2005
    ..Tumor necrosis factor-alpha (TNF-alpha), a cytokine secreted by adipose tissue and other cells, might play a role in insulin resistance...
  57. ncbi TCF7L2, dietary carbohydrate, and risk of type 2 diabetes in US women
    Marilyn C Cornelis
    Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
    Am J Clin Nutr 89:1256-62. 2009
    ..Dietary factors that increase the insulin demand might enhance the risk of T2D associated with TCF7L2 variants...
  58. ncbi Fat mass-and obesity-associated (FTO) gene variant is associated with obesity: longitudinal analyses in two cohort studies and functional test
    Lu Qi
    Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts, USA
    Diabetes 57:3145-51. 2008
    ..To examine the longitudinal association of fat mass-and obesity-associated (FTO) variant with obesity, circulating adipokine levels, and FTO expression in various materials from human and mouse...
  59. ncbi Dietary patterns and the risk of postmenopausal breast cancer
    Teresa T Fung
    Department of Nutrition, Simmons College, Boston, MA 02115, USA
    Int J Cancer 116:116-21. 2005
    ..However, a Western-type diet may elevate risk of breast cancer among smokers, and a prudent diet may protect against estrogen receptive-negative tumors...
  60. ncbi Primary prevention of diabetes: what can be done and how much can be prevented?
    Matthias B Schulze
    Department of Nutrition and Epidemiology, Boston, Massachusetts 02115, USA
    Annu Rev Public Health 26:445-67. 2005
    ..However, there is still a wide gap between what we know and what we practice in the field of public health; how to narrow that gap remains a major public health challenge...
  61. ncbi Low-carbohydrate diet scores and risk of type 2 diabetes in men
    Lawrence de Koning
    Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
    Am J Clin Nutr 93:844-50. 2011
    ..Fat and protein sources may influence whether low-carbohydrate diets are associated with type 2 diabetes (T2D)...
  62. ncbi Changes in diet and lifestyle and long-term weight gain in women and men
    Dariush Mozaffarian
    Division of Cardiovascular Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA, USA
    N Engl J Med 364:2392-404. 2011
    ..Specific dietary and other lifestyle behaviors may affect the success of the straightforward-sounding strategy "eat less and exercise more" for preventing long-term weight gain...
  63. ncbi Changes in alcohol consumption and subsequent risk of type 2 diabetes in men
    Michel M Joosten
    Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts, USA
    Diabetes 60:74-9. 2011
    ..The objective of this study was to investigate the association of 4-year changes in alcohol consumption with a subsequent risk of type 2 diabetes...
  64. ncbi Genome-wide association study identifies novel alleles associated with risk of cutaneous basal cell carcinoma and squamous cell carcinoma
    Hongmei Nan
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    Hum Mol Genet 20:3718-24. 2011
    ..21 (1.02-1.44); P= 0.03], were associated with an increased risk of SCC. These two variants were not associated with melanoma risk. We conclude that 6p25 and 13q32 are novel loci conferring susceptibility to non-melanoma skin cancer...
  65. ncbi Resistin is associated with biomarkers of inflammation while total and high-molecular weight adiponectin are associated with biomarkers of inflammation, insulin resistance, and endothelial function
    Jessica L Fargnoli
    Division of Endocrinology, Diabetes, and Metabolism, Department of Medicine, Harvard Medical School, Beth Israel Deaconess Medical Center, 330 Brookline Avenue, ST816, Boston, Massachusetts 02115, USA
    Eur J Endocrinol 162:281-8. 2010
    ..It remains to be elucidated which of these adipokines is associated primarily with biomarkers of all or only some of these categories, i.e. biomarkers of inflammation, endothelial dysfunction, and/or insulin secretion or insulinemia...
  66. ncbi Adolescent dairy product consumption and risk of type 2 diabetes in middle-aged women
    Vasanti S Malik
    Department of Nutrition, Harvard School of Public Health, Boston, MA, USA
    Am J Clin Nutr 94:854-61. 2011
    ..Type 2 diabetes (T2D) prevention has generally focused on the identification of risk factors in adulthood. Dairy product consumption in adults has been associated with a lower risk of T2D...
  67. ncbi Dietary glycemic index, glycemic load, cereal fiber, and plasma adiponectin concentration in diabetic men
    Lu Qi
    Department of Nutrition, Harvard School of Public Health, 665 Huntington Ave, Boston, MA 02115, USA
    Diabetes Care 28:1022-8. 2005
    ..Adiponectin may improve insulin sensitivity, reduce inflammation, and ameliorate glycemic control. However, few studies have evaluated dietary predictors of plasma adiponectin levels, especially among subjects with type 2 diabetes...
  68. ncbi Genome-wide association study identifies polymorphisms in LEPR as determinants of plasma soluble leptin receptor levels
    Qi Sun
    Department of Nutrition, Harvard School of Public Health, 655 Huntington Avenue, Boston, MA 02115, USA
    Hum Mol Genet 19:1846-55. 2010
    ..These data provide novel evidence revealing the role of polymorphisms in LEPR in modulating plasma levels of sOB-R and may further our understanding of the complex relationships among leptin, leptin receptor and diabetes-related traits...
  69. ncbi Sleep duration and snoring in relation to biomarkers of cardiovascular disease risk among women with type 2 diabetes
    Catherine J Williams
    Department of Endocrinology, Diabetes, and Metabolism, Beth Israel Deaconess Medical Center, Harvard Medical School, 330 Brookline Ave, Boston, MA 02115, USA
    Diabetes Care 30:1233-40. 2007
    ..We aim to determine whether sleep duration and/or snoring are associated with biomarkers of CVD in women with type 2 diabetes...
  70. ncbi Phobic anxiety is associated with higher serum concentrations of adipokines and cytokines in women with diabetes
    Aoife M Brennan
    Division of Endocrinology, Diabetes, and Metabolism, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA
    Diabetes Care 32:926-31. 2009
    ..We aimed to determine whether associations of phobic anxiety with several known markers of CVD might be contributors...
  71. ncbi A common genetic variant is associated with adult and childhood obesity
    Alan Herbert
    Department of Genetics and Genomics, Boston University Medical School, E613, 715 Albany Street, Boston, MA 02118, USA
    Science 312:279-83. 2006
    ..The obesity-predisposing genotype is present in 10% of individuals. Our study suggests that common genetic polymorphisms are important determinants of obesity...
  72. ncbi The association between magnesium intake and fasting insulin concentration in healthy middle-aged women
    Teresa T Fung
    Department of Nutrition, Simmons College, 300 The Fenway, Boston, MA 02215, USA
    J Am Coll Nutr 22:533-8. 2003
    ..We assessed the association between magnesium intake and fasting insulin levels in a large cohort of women...
  73. ncbi A genome-wide association study identifies novel alleles associated with hair color and skin pigmentation
    Jiali Han
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, and Harvard Medical School, Boston, Massachusetts, United States of America
    PLoS Genet 4:e1000074. 2008
    ..The signals detected in a region around the MC1R gene were explained by MC1R red hair color alleles. Our results suggest that the IRF4 and SLC24A4 loci are associated with human hair color and skin pigmentation...
  74. ncbi Chronic obstructive pulmonary disease, asthma, and risk of type 2 diabetes in women
    Jamal S Rana
    Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA 02115, USA
    Diabetes Care 27:2478-84. 2004
    ..Differences in the inflammation and cytokine profile between COPD and asthma might explain why COPD, but not asthma, is associated with increased risk of type 2 diabetes...
  75. ncbi Dietary fat and meat intake in relation to risk of type 2 diabetes in men
    Rob M van Dam
    Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts 02115, USA
    Diabetes Care 25:417-24. 2002
    ..To examine dietary fat and meat intake in relation to risk of type 2 diabetes...
  76. ncbi Determinants of plasma dihydrophylloquinone in men and women
    Arja T Erkkilä
    Cardiovascular Nutrition Laboratory, Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, Boston, MA 02111, USA
    Br J Nutr 93:701-8. 2005
    ..Despite this caveat, higher plasma dihydrophylloquinone was associated with higher dihydrophylloquinone intake and higher trans fatty acid intake...
  77. ncbi Low-carbohydrate-diet score and risk of type 2 diabetes in women
    Thomas L Halton
    Department of Nutrition, Harvard School of Public Health, Boston, MA 02215, USA
    Am J Clin Nutr 87:339-46. 2008
    ..Low-carbohydrate weight-loss diets remain popular; however, the long-term effects of these diets are not known...
  78. ncbi Coffee consumption and markers of inflammation and endothelial dysfunction in healthy and diabetic women
    Esther Lopez-Garcia
    Department of Nutrition and Epidemiology, Harvard Medical School, Boston, MA, USA
    Am J Clin Nutr 84:888-93. 2006
    ..In several short-term studies, coffee consumption has been associated with impairment of endothelial function...
  79. ncbi Depressive symptoms and risk of type 2 diabetes in women
    Cassandra Arroyo
    Department of Biostatistics, Harvard School of Public Health, Boston, Massachusetts, USA
    Diabetes Care 27:129-33. 2004
    ..To explore the relationship between depressive symptoms and incidence of type 2 diabetes in women...
  80. ncbi Dietary patterns and risk of mortality from cardiovascular disease, cancer, and all causes in a prospective cohort of women
    Christin Heidemann
    Department of Nutrition, Harvard School of Public Health, 665 Huntington Ave, Boston, MA 02215, USA
    Circulation 118:230-7. 2008
    ..The impact of overall dietary patterns that reflect actual eating behaviors on mortality caused by cardiovascular or other chronic diseases is largely unknown...
  81. ncbi Biomarkers of endothelial dysfunction and risk of type 2 diabetes mellitus
    James B Meigs
    General Medicine Division, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, Mass 02114, USA
    JAMA 291:1978-86. 2004
    ..Endothelial dysfunction occurs in diagnosed type 2 diabetes mellitus but may also precede development of diabetes...
  82. ncbi Comparison of self-reported and measured BMI as correlates of disease markers in US adults
    Mara A McAdams
    Department of Epidemiology, Harvard School of Public Health, 665 Huntington Avenue, Boston, MA 02115, USA
    Obesity (Silver Spring) 15:188-96. 2007
    ..The purpose of this study is to evaluate the validity of BMI based on self-reported data by comparison with technician-measured BMI and biomarkers of adiposity...
  83. ncbi Prospective study of dietary energy density and weight gain in women
    Maira Bes-Rastrollo
    Department of Nutrition, Harvard School of Public Health, Boston, MA
    Am J Clin Nutr 88:769-77. 2008
    ..Little is known about the long-term effects of dietary energy density (ED) on weight gain...
  84. ncbi Adherence to a DASH-style diet and risk of coronary heart disease and stroke in women
    Teresa T Fung
    Department of Nutrition, Simmons College, 300 The Fenway, and Department of Medicine, Brigham and Women s Hospital, Boston, MA 02115, USA
    Arch Intern Med 168:713-20. 2008
    ..Our objective was to assess the association between a DASH-style diet adherence score and risk of coronary heart disease (CHD) and stroke in women...
  85. ncbi Association of diet with glycated hemoglobin during intensive treatment of type 1 diabetes in the Diabetes Control and Complications Trial
    Linda M Delahanty
    Massachusetts General Hospital Diabetes Center and Harvard Medical School, Boston, MA 02114, USA
    Am J Clin Nutr 89:518-24. 2009
    ..Persons with type 1 diabetes have received widely varying dietary advice based on putative effects on glycemic control...
  86. ncbi Whole-grain intake and the risk of type 2 diabetes: a prospective study in men
    Teresa T Fung
    Programs in Nutrition, Simmons College, Boston, MA 02115, USA
    Am J Clin Nutr 76:535-40. 2002
    ..Certain dietary components may play a role in the prevention of type 2 diabetes...
  87. ncbi Coffee consumption and risk for type 2 diabetes mellitus
    Eduardo Salazar-Martinez
    Harvard School of Public Health, Channing Laboratory, Harvard Medical School, and Brigham and Women's Hospital, Boston, Massachusetts 02215, USA
    Ann Intern Med 140:1-8. 2004
    ..CONCLUSIONS: These data suggest that long-term coffee consumption is associated with a statistically significantly lower risk for type 2 diabetes...
  88. ncbi Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index
    Elizabeth K Speliotes
    Metabolism Initiative and Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts, USA
    Nat Genet 42:937-48. 2010
    ..Furthermore, genes in other newly associated loci may provide new insights into human body weight regulation...
  89. ncbi Whole-grain, cereal fiber, bran, and germ intake and the risks of all-cause and cardiovascular disease-specific mortality among women with type 2 diabetes mellitus
    Meian He
    Department of Nutrition, Harvard School of Public Health, 665 Huntington Ave, Boston, MA 02115, USA
    Circulation 121:2162-8. 2010
    ..This study investigated whole grain and its components cereal fiber, bran, and germ in relation to all-cause and CVD-specific mortality in patients with type 2 diabetes mellitus...
  90. ncbi Potato and french fry consumption and risk of type 2 diabetes in women
    Thomas L Halton
    Department of Nutrition and Epidemiology, Department of Medicine, Harvard Medical School and Brigham and Women's Hospital, Boston, MA 02215, USA
    Am J Clin Nutr 83:284-90. 2006
    ..CONCLUSIONS: Our findings suggest a modest positive association between the consumption of potatoes and the risk of type 2 diabetes in women. This association was more pronounced when potatoes were substituted for whole grains...
  91. ncbi Serum adiponectin and renal dysfunction in men with type 2 diabetes
    Julie Lin
    Renal Division, Brigham and Women s Hospital, 75 Francis Street, Boston, MA 02115, USA
    Diabetes Care 30:239-44. 2007
    ..In contrast, serum levels of adiponectin are elevated in end-stage renal disease. We sought to investigate the relation between adiponectin and mild to moderate renal dysfunction in men with type 2 diabetes...
  92. ncbi Long-chain omega-3 fatty acids, fish intake, and the risk of type 2 diabetes mellitus
    Manas Kaushik
    Departments of Nutrition, Harvard Medical School and Brigham and Women s Hospital, Boston, MA, USA
    Am J Clin Nutr 90:613-20. 2009
    ..The role of long-chain omega-3 (n-3) fatty acids (LCFAs) in the development of T2DM remains unresolved. Objective: We examined the association between dietary LCFAs and incidence of T2DM in 3 prospective cohorts of women and men...
  93. ncbi Intake of sugar-sweetened beverages and weight gain: a systematic review
    Vasanti S Malik
    Department of Nutrition, Harvard School of Public Health, Boston, MA, USA
    Am J Clin Nutr 84:274-88. 2006
    ..Although more research is needed, sufficient evidence exists for public health strategies to discourage consumption of sugary drinks as part of a healthy lifestyle...
  94. ncbi Alcohol consumption and type 2 diabetes: influence of genetic variation in alcohol dehydrogenase
    Joline W J Beulens
    Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts, USA
    Diabetes 56:2388-94. 2007
    ..We sought to investigate whether a polymorphism in the alcohol dehydrogenase 1c (ADH1C) gene modifies the association between alcohol consumption and type 2 diabetes...
  95. ncbi Plasma and erythrocyte biomarkers of dairy fat intake and risk of ischemic heart disease
    Qi Sun
    Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
    Am J Clin Nutr 86:929-37. 2007
    ..The relation between dairy product intake and the risk of ischemic heart disease (IHD) remains controversial...
  96. ncbi Coffee consumption and risk of cardiovascular diseases and all-cause mortality among men with type 2 diabetes
    Weili Zhang
    Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts, USA
    Diabetes Care 32:1043-5. 2009
    ..Coffee consumption has been linked to detrimental acute metabolic and hemodynamic effects. We investigated coffee consumption in relation to risk of CVDs and mortality in diabetic men...
  97. ncbi Adherence to healthy eating patterns is associated with higher circulating total and high-molecular-weight adiponectin and lower resistin concentrations in women from the Nurses' Health Study
    Jessica L Fargnoli
    Division of Endocrinology, Diabetes, and Metabolism, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02115, USA
    Am J Clin Nutr 88:1213-24. 2008
    ..Adherence to a healthy dietary pattern, such as the Alternate Healthy Eating Index (AHEI), is associated with a lower risk of diabetes and atherosclerosis...
  98. ncbi Peroxisome proliferator-activated receptor-gamma2 P12A polymorphism and risk of coronary heart disease in US men and women
    Tobias Pischon
    Department of Nutrition and Epidemiology, Harvard School of Public Health, Boston, Mass, USA
    Arterioscler Thromb Vasc Biol 25:1654-8. 2005
    ..Studies suggest that the A12 allele is associated with reduced risk of type 2 diabetes; however, data on the risk of coronary heart disease (CHD) are scarce and controversial...
  99. ncbi Prevalence of metabolic syndrome and its relation to body composition in a Chinese rural population
    Yan Feng
    Program for Population Genetics, Harvard School of Public Health, 665 Huntington Avenue, FXB-101, Boston, MA 02115, USA
    Obesity (Silver Spring) 14:2089-98. 2006
    ..Significant gender differences in MetS prevalence were observed. The waist circumference is a good surrogate for abdominal fat percentage...
  100. ncbi The Mediterranean diet and mortality--olive oil and beyond
    Frank B Hu
    Department of Nutrition, Harvard School of Public Health, and the Channing Laboratory, Department of Medicine, Brigham and Women's Hospital, Boston, USA
    N Engl J Med 348:2595-6. 2003
  101. ncbi Calcium and dairy intakes in relation to long-term weight gain in US men
    Swapnil N Rajpathak
    Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    Am J Clin Nutr 83:559-66. 2006
    ..The role of calcium in the maintenance of body weight remains controversial...