Research Topics
Genomes and Genes
| F B HuSummaryAffiliation: Harvard University Country: USA Publications
| Collaborators
|
Detail Information
Publications
Red meat consumption and mortality: results from 2 prospective cohort studiesAn Pan
Departments of Nutrition and Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
Arch Intern Med 172:555-63. 2012..Red meat consumption has been associated with an increased risk of chronic diseases. However, its relationship with mortality remains uncertain...
Gene-environment interactions in the development of type 2 diabetes: recent progress and continuing challengesMarilyn C Cornelis
Department of Nutrition, Harvard School of Public Health, Harvard University, Boston, Massachusetts 02115, USA
Annu Rev Nutr 32:245-59. 2012..Nonetheless, continued investment in gene-environment interaction studies through large collaborative efforts holds promise in furthering our understanding of the interplay between genetic and environmental factors...
Bidirectional association between depression and metabolic syndrome: a systematic review and meta-analysis of epidemiological studiesAn Pan
Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts, USA
Diabetes Care 35:1171-80. 2012..However, the results have been inconsistent. This meta-analysis aimed to summarize the current evidence from cross-sectional and prospective cohort studies that evaluated this association...
Sweetened beverage consumption, incident coronary heart disease, and biomarkers of risk in menLawrence de Koning
Harvard School of Public Health, 665 Huntington Ave, Boston, MA 02115, USA
Circulation 125:1735-41, S1. 2012..Few studies have tested for a relationship with coronary heart disease (CHD) or intermediate biomarkers. The role of artificially sweetened beverages is also unclear...
Diet and coronary heart disease: findings from the Nurses' Health Study and Health Professionals' Follow-up StudyF B Hu
Department of Nutrition, Harvard School of Public Health, 665 Huntington Ave, Boston, MA 02115, USA
J Nutr Health Aging 5:132-8. 2001..These studies, along with metabolic, clinical and other epidemiological studies, have provided strong evidence for a major role of dietary modification in the prevention of coronary heart disease (CHD)...
Fish and omega-3 fatty acid intake and risk of coronary heart disease in womenFrank B Hu
Department of Nutrition, Harvard School of Public Health, 665 Huntington Ave, Boston, MA 02115, USA
JAMA 287:1815-21. 2002..Higher consumption of fish and omega-3 fatty acids has been associated with a lower risk of coronary heart disease (CHD) in men, but limited data are available regarding women...
Dietary pattern analysis: a new direction in nutritional epidemiologyFrank B Hu
Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts 02115, USA
Curr Opin Lipidol 13:3-9. 2002....
Sugar-sweetened beverages and risk of obesity and type 2 diabetes: epidemiologic evidenceFrank B Hu
Departments of Nutrition and Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
Physiol Behav 100:47-54. 2010..Consumption of SSBs should therefore be replaced by healthy alternatives such as water, to reduce risk of obesity and chronic diseases...
Preventing chronic diseases by promoting healthy diet and lifestyle: public policy implications for ChinaF B Hu
Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
Obes Rev 12:552-9. 2011..To achieve the goals set by the Healthy China 2020 programme, prevention of chronic diseases should be elevated to a national public policy priority...
Physical activity and television watching in relation to risk for type 2 diabetes mellitus in menF B Hu
Department of Nutrition, Harvard School of Public Health, 665 Huntington Ave, Boston, MA 02115, USA
Arch Intern Med 161:1542-8. 2001..Television (TV) watching, a major sedentary behavior in the United States, has been associated with obesity. We hypothesized that prolonged TV watching may increase risk for type 2 diabetes...
Globalization of diabetes: the role of diet, lifestyle, and genesFrank B Hu
Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts, USA
Diabetes Care 34:1249-57. 2011..To curb the escalating diabetes epidemic, primary prevention through promotion of a healthy diet and lifestyle should be a global public policy priority...
The impact of diabetes mellitus on mortality from all causes and coronary heart disease in women: 20 years of follow-upF B Hu
Department of Nutrition, Harvard School of Public Health, 665 Huntington Ave, Boston, MA 02115, USA
Arch Intern Med 161:1717-23. 2001..Few data are available on the long-term impact of type 2 diabetes mellitus on total mortality and fatal coronary heart disease (CHD) in women...
Diet, lifestyle, and the risk of type 2 diabetes mellitus in womenF B Hu
Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
N Engl J Med 345:790-7. 2001..Previous studies have examined individual dietary and lifestyle factors in relation to type 2 diabetes, but the combined effects of these factors are largely unknown...
Elevated risk of cardiovascular disease prior to clinical diagnosis of type 2 diabetesFrank B Hu
Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts 02115, USA
Diabetes Care 25:1129-34. 2002..To examine whether the risk of cardiovascular disease (CVD) is elevated before clinical diagnosis of type 2 diabetes in women...
Optimal diets for prevention of coronary heart diseaseFrank B Hu
Department of Nutrition, Harvard School of Public Health, 665 Huntington Ave, Boston, MA 02115, USA
JAMA 288:2569-78. 2002..Thus, identification of the dietary changes that most effectively prevent CHD is critical...
Adiposity as compared with physical activity in predicting mortality among womenFrank B Hu
Department of Nutrition, Harvard School of Public Health, Boston, Copyright 2004 Massachusetts Medical Society USA
N Engl J Med 351:2694-703. 2004..Whether higher levels of physical activity can counteract the elevated risk of death associated with adiposity is controversial...
Genetic variation at the adiponectin locus and risk of type 2 diabetes in womenFrank B Hu
Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts 02115, USA
Diabetes 53:209-13. 2004..03-2.08, P = 0.03). These data suggest a potential interaction between the adiponectin genotype and PPAR gamma genotype or obesity, but these analyses should be considered exploratory and require further investigation in larger studies...
Protein, body weight, and cardiovascular healthFrank B Hu
Harvard School of Public Health, Boston, MA 02115, USA
Am J Clin Nutr 82:242S-247S. 2005..Although optimal amounts and sources of protein cannot be determined at this time, evidence suggests a potential benefit of partially replace refined carbohydrates with protein sources low in saturated fats...
Plant-based foods and prevention of cardiovascular disease: an overviewFrank B Hu
Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
Am J Clin Nutr 78:544S-551S. 2003..Such diets, which also have many other health benefits, deserve more emphasis in dietary recommendations to prevent chronic diseases...
Overweight and obesity in women: health risks and consequencesFrank B Hu
Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts 02115, USA
J Womens Health (Larchmt) 12:163-72. 2003..Curbing the twin epidemics of obesity and diabetes calls for not only changes in diet and lifestyle at individual levels but also changes in policy, physical and social environment, and cultural norms...
Sedentary lifestyle and risk of obesity and type 2 diabetesFrank B Hu
Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts 02115, USA
Lipids 38:103-8. 2003..Thus, public health campaigns to reduce the risk of obesity and type 2 diabetes should promote not only increasing exercise levels but also decreasing sedentary behaviors, especially prolonged TV watching...
Television watching and other sedentary behaviors in relation to risk of obesity and type 2 diabetes mellitus in womenFrank B Hu
Department of Nutrition, Harvard School of Public Health, Boston, Mass 02115, USA
JAMA 289:1785-91. 2003..Current public health campaigns to reduce obesity and type 2 diabetes have largely focused on increasing exercise, but have paid little attention to the reduction of sedentary behaviors...
Fish and long-chain omega-3 fatty acid intake and risk of coronary heart disease and total mortality in diabetic womenFrank B Hu
Department of Nutrition, Harvard School of Public Health, 665 Huntington Ave, Boston, Mass 02115, USA
Circulation 107:1852-7. 2003....
The role of diet and lifestyle modifications in the statin eraFrank B Hu
Department of Nutrition and Epidemiology, Harvard School of Public Health, 665 Huntington Ave, Boston, MA 02115, USA
J Am Diet Assoc 105:1718-21. 2005
The impact of diabetes and prediabetes on risk of cardiovascular disease and mortalityFrank B Hu
Department of Nutrition and Epidemiology, Harvard School of Public Health, 665 Huntington Avenue, Boston, MA 02115, U S A
Drugs Today (Barc) 38:769-75. 2002..In addition, the incidence of cardiovascular disease is elevated long before the clinical diagnosis of diabetes...
The effects of high protein diets on thermogenesis, satiety and weight loss: a critical reviewThomas L Halton
Dept of Nutrition, Harvard School of Public Health, 665 Huntington Ave, Boston, MA 02115, USA
J Am Coll Nutr 23:373-85. 2004..Although recent evidence supports potential benefit, rigorous longer-term studies are needed to investigate the effects of high protein diets on weight loss and weight maintenance...
Prospective study of cataract extraction and risk of coronary heart disease in womenF B Hu
Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
Am J Epidemiol 153:875-81. 2001..84, 95% CI: 1.29, 2.64). These findings are compatible with current hypotheses relating oxidative damage and tissue aging to the development of cataract and CHD...
Dietary saturated fats and their food sources in relation to the risk of coronary heart disease in womenF B Hu
Departments of Nutrition and Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA Hospital
Am J Clin Nutr 70:1001-8. 1999..Metabolic studies suggest that saturated fatty acids differ in their effects on blood lipids...
Walking compared with vigorous physical activity and risk of type 2 diabetes in women: a prospective studyF B Hu
Department of Nutrition, Harvard School of Public Health, Boston, Mass 02115, USA
JAMA 282:1433-9. 1999..Although many studies suggest that physical activity may reduce risk of type 2 diabetes, the role of moderate-intensity activity such as walking is not well understood...
Dietary protein and risk of ischemic heart disease in womenF B Hu
Departments of Nutrition and Epidemiology, Harvard School of Public Health, Boston, MA, USA
Am J Clin Nutr 70:221-7. 1999..Prospective data on the relation of protein intake to risk of ischemic heart disease are sparse...
Age at natural menopause and risk of cardiovascular diseaseF B Hu
Department of Nutrition, Harvard School of Public Health, Boston, Mass 02115, USA
Arch Intern Med 159:1061-6. 1999..Early natural menopause has been postulated to increase the risk of cardiovascular disease...
Dietary intake of alpha-linolenic acid and risk of fatal ischemic heart disease among womenF B Hu
Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
Am J Clin Nutr 69:890-7. 1999..Experimental studies in laboratory animals and humans suggest that alpha-linolenic acid (18:3n-3) may reduce the risk of arrhythmia...
A prospective study of egg consumption and risk of cardiovascular disease in men and womenF B Hu
Department of Nutrition, Harvard School of Public Health, Boston, Mass 02115, USA
JAMA 281:1387-94. 1999..Reduction in egg consumption has been widely recommended to lower blood cholesterol levels and prevent coronary heart disease (CHD). Epidemiologic studies on egg consumption and risk of CHD are sparse...
Prospective study of adult onset diabetes mellitus (type 2) and risk of colorectal cancer in womenF B Hu
Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
J Natl Cancer Inst 91:542-7. 1999..We prospectively examined the relationship between diabetes and risk of colorectal cancer in a cohort of 118403 women aged 30 through 55 years who were without previously diagnosed cancer at baseline in 1976...
Reproducibility and validity of dietary patterns assessed with a food-frequency questionnaireF B Hu
Department of Nutrition, Harvard School of Public Health, Brigham and Women s Hospital, Boston, MA 02115, USA
Am J Clin Nutr 69:243-9. 1999..Recently, the analysis of dietary patterns has emerged as a possible approach to examining diet-disease relations...
Frequent nut consumption and risk of coronary heart disease in women: prospective cohort studyF B Hu
Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
BMJ 317:1341-5. 1998..To examine the relation between nut consumption and risk of coronary heart disease in a cohort of women from the Nurses' Health Study...
Physical activity and risk of stroke in womenF B Hu
Department of Nutrition, Harvard School of Public Health, 665 Huntington Ave, Boston, MA 02115
JAMA 283:2961-7. 2000..Persuasive evidence has demonstrated that increased physical activity is associated with substantial reduction in risk of coronary heart disease. However, the role of physical activity in the prevention of stroke is less well established...
Snoring and risk of cardiovascular disease in womenF B Hu
Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts 02115, USA
J Am Coll Cardiol 35:308-13. 2000..To examine prospectively the association between snoring and incidence of cardiovascular disease (CVD) in women...
Diet and lifestyle influences on risk of coronary heart diseaseFrank B Hu
Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
Curr Atheroscler Rep 11:257-63. 2009..Diet and lifestyle modification, combined with pharmacologic treatment of hypertension and high lipid levels (if necessary), could prevent the vast majority of CHD events...
Physical activity and risk for cardiovascular events in diabetic womenF B Hu
Department of Nutrition, Harvard School of Public Health, 665 Huntington Avenue, Boston, MA 02115, USA
Ann Intern Med 134:96-105. 2001..Increased physical activity has been associated with reduced risk for cardiovascular disease in the general population, but data are limited on its role among persons with type 2 diabetes mellitus...
Leptin concentrations in relation to overall adiposity, fat distribution, and blood pressure in a rural Chinese populationF B Hu
Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
Int J Obes Relat Metab Disord 25:121-5. 2001..To examine the associations between leptin levels and body mass index (BMI), fat distribution (reflected by waist to hip ratio and skinfold measurements), and blood pressure in a rural Chinese population...
Trends in the incidence of coronary heart disease and changes in diet and lifestyle in womenF B Hu
Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
N Engl J Med 343:530-7. 2000..However, the effects of changes in diet and lifestyle on trends in coronary disease are largely unknown...
Types of dietary fat and risk of coronary heart disease: a critical reviewF B Hu
Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts 02115, USA
J Am Coll Nutr 20:5-19. 2001..We also discuss the implications of the available evidence in the context of current dietary recommendations...
Moderate alcohol consumption and risk of coronary heart disease among women with type 2 diabetes mellitusC G Solomon
Division of Women s Health, Department of Medicine, Brigham and Women s Hospital, Boston, MA 02115, USA
Circulation 102:494-9. 2000..We assessed prospectively the association between moderate alcohol intake and CHD risk in women with type 2 diabetes mellitus, a group at high risk for cardiovascular disease...
A prospective study of dietary glycemic load, carbohydrate intake, and risk of coronary heart disease in US womenS Liu
Departments of Epidemiology and Nutrition, The Harvard School of Public Health, Boston, MA 02215, USA
Am J Clin Nutr 71:1455-61. 2000..Little is known about the effects of the amount and type of carbohydrates on risk of coronary heart disease (CHD)...
Folate and vitamin B6 from diet and supplements in relation to risk of coronary heart disease among womenE B Rimm
Department of Epidemiology, Harvard School of Public Health, Boston, Mass 02115, USA
JAMA 279:359-64. 1998..Hyperhomocysteinemia is caused by genetic and lifestyle influences, including low intakes of folate and vitamin B6. However, prospective data relating intake of these vitamins to risk of coronary heart disease (CHD) are not available...
A prospective study of whole-grain intake and risk of type 2 diabetes mellitus in US womenS Liu
Brigham and Women s Hospital, Harvard Medical School, Boston, USA
Am J Public Health 90:1409-15. 2000..This study examined the association between intake of whole vs refined grain and the risk of type 2 diabetes mellitus...
Whole-grain consumption and risk of coronary heart disease: results from the Nurses' Health StudyS Liu
Division of Preventive Medicine and Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02215, USA
Am J Clin Nutr 70:412-9. 1999..Although current dietary guidelines for Americans recommend increased intake of grain products to prevent coronary heart disease (CHD), epidemiologic data relating whole-grain intake to the risk of CHD are sparse...
Obesity genotype score and cardiovascular risk in women with type 2 diabetes mellitusMeian He
Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
Arterioscler Thromb Vasc Biol 30:327-32. 2010..To investigate the associations between obesity-predisposing genetic variants, cardiovascular biomarkers, and cardiovascular disease (CVD) risk in women with preexisting type 2 diabetes mellitus...
Bidirectional association between depression and obesity in middle-aged and older womenA Pan
Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
Int J Obes (Lond) 36:595-602. 2012..We aimed to examine the bidirectional relationship in middle-aged and elderly women...
Smoking and mortality among women with type 2 diabetes: The Nurses' Health Study cohortW K Al-Delaimy
Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
Diabetes Care 24:2043-8. 2001..To assess the relationship between cigarette smoking and mortality among women with type 2 diabetes in the Nurses' Health Study cohort...
A prospective study of walking as compared with vigorous exercise in the prevention of coronary heart disease in womenJ E Manson
Department of Medicine, Harvard Medical School and Brigham and Women s Hospital, Boston, MA 02115, USA
N Engl J Med 341:650-8. 1999..The role of walking, as compared with vigorous exercise, in the prevention of coronary heart disease remains controversial, and data for women on this topic are sparse...
The effect of fruit and vegetable intake on risk for coronary heart diseaseK J Joshipura
Harvard School of Public Health, 677 Huntington Avenue, Boston, MA 02115, USA
Ann Intern Med 134:1106-14. 2001..CONCLUSIONS: Consumption of fruits and vegetables, particularly green leafy vegetables and vitamin C-rich fruits and vegetables, appears to have a protective effect against coronary heart disease...
Dietary glycemic load assessed by food-frequency questionnaire in relation to plasma high-density-lipoprotein cholesterol and fasting plasma triacylglycerols in postmenopausal womenS Liu
Division of Preventive Medicine and the Channing Laboratory, The Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
Am J Clin Nutr 73:560-6. 2001..In epidemiologic studies, dietary glycemic load (GL) is positively associated with risk of coronary artery disease and type 2 diabetes...
Joint role of non-HDL cholesterol and glycated haemoglobin in predicting future coronary heart disease events among women with type 2 diabetesM B Schulze
Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts, USA
Diabetologia 47:2129-36. 2004..Therapies to lower CHD risk in diabetic patients should emphasise both glycaemic control and lipid lowering...
Primary prevention of diabetes: what can be done and how much can be prevented?Matthias B Schulze
Department of Nutrition and Epidemiology, Boston, Massachusetts 02115, USA
Annu Rev Public Health 26:445-67. 2005..However, there is still a wide gap between what we know and what we practice in the field of public health; how to narrow that gap remains a major public health challenge...
Physical activity in relation to cardiovascular disease and total mortality among men with type 2 diabetesMihaela Tanasescu
Department of Nutrition, Harvard School of Public Health, Boston, Mass, USA
Circulation 107:2435-9. 2003..CVD risk and mortality are increased in type 2 diabetes. Few epidemiological studies have investigated the effect of physical activity on these outcomes among type 2 diabetics...
Phylloquinone intake as a marker for coronary heart disease risk but not stroke in womenA T Erkkilä
Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, Boston, MA, USA
Eur J Clin Nutr 59:196-204. 2005..To examine the feasibility of using phylloquinone intake as a marker for coronary heart disease (CHD) and stroke risk in women...
Coffee consumption and risk of cardiovascular events and all-cause mortality among women with type 2 diabetesW L Zhang
Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
Diabetologia 52:810-7. 2009..Coffee has been linked to both beneficial and harmful health effects, but data on its relationship with cardiovascular disease and mortality in patients with type 2 diabetes are sparse...
Association between dietary patterns and plasma biomarkers of obesity and cardiovascular disease riskT T Fung
Department of Nutrition, Harvard School of Public Health, Boston, USA
Am J Clin Nutr 73:61-7. 2001..Although the effects of individual foods or nutrients on the development of diseases and their risk factors have been investigated in many studies, little attention has been given to the effect of overall dietary patterns...
A common genetic variant is associated with adult and childhood obesityAlan Herbert
Department of Genetics and Genomics, Boston University Medical School, E613, 715 Albany Street, Boston, MA 02118, USA
Science 312:279-83. 2006..The obesity-predisposing genotype is present in 10% of individuals. Our study suggests that common genetic polymorphisms are important determinants of obesity...
Fruit and vegetable intake and risk of major chronic diseaseHsin-Chia Hung
Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
J Natl Cancer Inst 96:1577-84. 2004..The benefits appeared to be primarily for cardiovascular disease and not for cancer...
Genetic polymorphisms of angiotensin-2 type 1 receptor and angiotensinogen and risk of renal dysfunction and coronary heart disease in type 2 diabetes mellitusJulie Lin
Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
BMC Nephrol 10:9. 2009....
A prospective study of lipoprotein(a) and risk of coronary heart disease among women with type 2 diabetesI Shai
Department of Nutrition, Harvard School of Public Health, Boston, MA, USA
Diabetologia 48:1469-76. 2005..We examined the association between lipoprotein (Lp)(a) and CHD among women with type 2 diabetes...
Dietary fat intake and risk of type 2 diabetes in womenJ Salmeron
Departments of Nutrition and Epidemiology, Harvard School of Public Health, Boston 02115, USA
Am J Clin Nutr 73:1019-26. 2001..The long-term relations between specific types of dietary fat and risk of type 2 diabetes remain unclear...
Lipid and inflammatory biomarkers and kidney function decline in type 2 diabetesJ Lin
Renal Division, MRB 4, Brigham and Women s Hospital, 75 Francis Street, Boston, MA 02115, USA
Diabetologia 53:263-7. 2010..Potentially modifiable biomarkers may influence the decline in estimated GFR (eGFR), but few data are currently available in type 2 diabetic adults...
Sweetened beverage consumption and risk of coronary heart disease in womenTeresa T Fung
Department of Nutrition, Simmons College, Boston, MA 02115, USA
Am J Clin Nutr 89:1037-42. 2009..Previous studies have linked full-calorie sugar-sweetened beverages (SSBs) with greater weight gain and an increased risk of type 2 diabetes...
Regular consumption of nuts is associated with a lower risk of cardiovascular disease in women with type 2 diabetesTricia Y Li
Department of Nutrition, and 4Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
J Nutr 139:1333-8. 2009..These data suggest that frequent nut and peanut butter consumption is associated with a significantly lower CVD risk in women with type 2 diabetes...
Dietary, lifestyle, and clinical predictors of lipoprotein-associated phospholipase A2 activity in individuals without coronary artery diseaseIda J Hatoum
Department of Nutrition and Epidemiology, Harvard School of Public Health, Boston MA, USA
Am J Clin Nutr 91:786-93. 2010..Elevated lipoprotein-associated phospholipase A(2) (Lp-PLA(2)) may be positively associated with risk of coronary artery disease, yet little is known about potentially modifiable factors related to Lp-PLA(2)...
Prospective study of major dietary patterns and stroke risk in womenTeresa T Fung
Department of Nutrition, Simmons College, 300 The Fenway, Boston, MA 02115, USA
Stroke 35:2014-9. 2004..Many foods have been suggested to influence the risk of stroke. However, no previous studies have examined the relationship between overall dietary patterns and risk of stroke...
Changes in caffeine intake and long-term weight change in men and womenEsther Lopez-Garcia
Department of Nutrition, Harvard School of Public Health, Cambridge, MA, USA
Am J Clin Nutr 83:674-80. 2006..001). CONCLUSION: Increases in caffeine intake may lead to a small reduction in long-term weight gain...
Alcohol consumption and risk of coronary heart disease among men with type 2 diabetes mellitusM Tanasescu
Nutrition, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA
J Am Coll Cardiol 38:1836-42. 2001..The goal of this study was to examine the relationship between alcohol intake and risk of coronary heart disease (CHD) among men with type 2 diabetes...
Moderate alcohol intake and markers of inflammation and endothelial dysfunction among diabetic menI Shai
Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts, USA
Diabetologia 47:1760-7. 2004..It remains to be determined whether there is an association between alcohol and inflammation in individuals with diabetes...
Dietary fat and meat intake in relation to risk of type 2 diabetes in menRob M van Dam
Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts 02115, USA
Diabetes Care 25:417-24. 2002..To examine dietary fat and meat intake in relation to risk of type 2 diabetes...
Genetic predisposition, Western dietary pattern, and the risk of type 2 diabetes in menLu Qi
Department of Nutrition, Harvard School of Public Health, Boston, MA, USA
Am J Clin Nutr 89:1453-8. 2009..A widely held hypothesis is that interactions between genetic predisposition and Western-type lifestyle contribute to the epidemic of type 2 diabetes (T2D). No study has tested this hypothesis...
TCF7L2, dietary carbohydrate, and risk of type 2 diabetes in US womenMarilyn C Cornelis
Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
Am J Clin Nutr 89:1256-62. 2009..Dietary factors that increase the insulin demand might enhance the risk of T2D associated with TCF7L2 variants...
A genome-wide association study identifies novel alleles associated with hair color and skin pigmentationJiali Han
Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, and Harvard Medical School, Boston, Massachusetts, United States of America
PLoS Genet 4:e1000074. 2008..The signals detected in a region around the MC1R gene were explained by MC1R red hair color alleles. Our results suggest that the IRF4 and SLC24A4 loci are associated with human hair color and skin pigmentation...
The association between magnesium intake and fasting insulin concentration in healthy middle-aged womenTeresa T Fung
Department of Nutrition, Simmons College, 300 The Fenway, Boston, MA 02215, USA
J Am Coll Nutr 22:533-8. 2003..We assessed the association between magnesium intake and fasting insulin levels in a large cohort of women...
Chronic obstructive pulmonary disease, asthma, and risk of type 2 diabetes in womenJamal S Rana
Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA 02115, USA
Diabetes Care 27:2478-84. 2004..Differences in the inflammation and cytokine profile between COPD and asthma might explain why COPD, but not asthma, is associated with increased risk of type 2 diabetes...
Whole grain consumption and risk of ischemic stroke in women: A prospective studyS Liu
Division of Preventive Medicine, Bringham and Women s Hospital, 900 Commonwealth Ave E, Boston, MA 02215, USA
JAMA 284:1534-40. 2000..Although increased intake of grain products has been recommended to prevent cardiovascular disease (CVD), prospective data examining the relation of whole grain intake to risk of ischemic stroke are sparse, especially among women...
Long or highly irregular menstrual cycles as a marker for risk of type 2 diabetes mellitusC G Solomon
Division of Women s Health, Brigham and Women s Hospital, 75 Francis St, Boston, MA 02115, USA
JAMA 286:2421-6. 2001..Although oligomenorrhea has been associated cross-sectionally with insulin resistance and glucose intolerance, it is not known whether oligomenorrhea is a marker for increased future risk of type 2 diabetes mellitus (DM)...
Dietary patterns, meat intake, and the risk of type 2 diabetes in womenTeresa T Fung
Department of Nutrition, Simmons College, Boston, Mass 02115, USA
Arch Intern Med 164:2235-40. 2004..To examine the association between major dietary patterns and risk of type 2 diabetes mellitus in a cohort of women...
Associations of diet with albuminuria and kidney function declineJulie Lin
Renal Division, Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, 75 Francis Street, Boston, MA 02115, USA
Clin J Am Soc Nephrol 5:836-43. 2010..Sparse longitudinal data exist on how diet influences microalbuminuria and estimated GFR (eGFR) decline in people with well-preserved kidney function...
Low-carbohydrate-diet score and the risk of coronary heart disease in womenThomas L Halton
Departments of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
N Engl J Med 355:1991-2002. 2006..When vegetable sources of fat and protein are chosen, these diets may moderately reduce the risk of coronary heart disease...
Circulating levels of endothelial adhesion molecules and risk of diabetes in an ethnically diverse cohort of womenYiqing Song
Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
Diabetes 56:1898-904. 2007..S. postmenopausal women, implicating an etiological role of endothelial dysfunction in the pathogenesis of type 2 diabetes...
Adherence to the Mediterranean dietary pattern is positively associated with plasma adiponectin concentrations in diabetic womenChristos S Mantzoros
Division of Endocrinology, Diabetes, and Metabolism, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA and Nutrition, Harvard School of Public Health, Boston, MA, USA
Am J Clin Nutr 84:328-35. 2006..Close adherence to a Mediterranean-type diet is associated with higher adiponectin concentrations...
Glycemic index, glycemic load, and cereal fiber intake and risk of type 2 diabetes in US black womenSupriya Krishnan
Slone Epidemiology Center, Boston, MA 02215, USA
Arch Intern Med 167:2304-9. 2007..Previous studies of carbohydrate quality and risk of type 2 diabetes mellitus have yielded inconsistent findings. Because diet is in part culturally determined, a study of dietary factors in US black women is of interest...
Determinants of plasma dihydrophylloquinone in men and womenArja T Erkkilä
Cardiovascular Nutrition Laboratory, Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, Boston, MA 02111, USA
Br J Nutr 93:701-8. 2005..Despite this caveat, higher plasma dihydrophylloquinone was associated with higher dihydrophylloquinone intake and higher trans fatty acid intake...
Dietary patterns and the risk of coronary heart disease in womenT T Fung
Department of Nutrition, Harvard School of Public Health, Boston, MA, USA
Arch Intern Med 161:1857-62. 2001..Although substantial information on individual nutrients or foods and risk of coronary heart disease (CHD) is available, little is known about the role of overall eating pattern...
Genetic variation in the hepatic lipase gene and the risk of coronary heart disease among US diabetic men: potential interaction with obesityC Zhang
Department of Nutrition, Harvard School of Public Health, 665 Huntington Avenue, Boston, MA, 02115, USA
Diabetologia 49:1552-9. 2006..Moreover, data on this association among diabetic patients are limited. We investigated the association of the LIPC polymorphism with CHD risk among US diabetic men and evaluated whether this association was modified by adiposity status...
Dietary modulation of endothelial function: implications for cardiovascular diseaseA A Brown
Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
Am J Clin Nutr 73:673-86. 2001..This article reviews clinical and experimental evidence regarding the role of these nutrients in modulating endothelial function and their potential to prevent cardiovascular disease...
Dietary patterns and risk of mortality from cardiovascular disease, cancer, and all causes in a prospective cohort of womenChristin Heidemann
Department of Nutrition, Harvard School of Public Health, 665 Huntington Ave, Boston, MA 02215, USA
Circulation 118:230-7. 2008..The impact of overall dietary patterns that reflect actual eating behaviors on mortality caused by cardiovascular or other chronic diseases is largely unknown...
Low-carbohydrate-diet score and risk of type 2 diabetes in womenThomas L Halton
Department of Nutrition, Harvard School of Public Health, Boston, MA 02215, USA
Am J Clin Nutr 87:339-46. 2008..Low-carbohydrate weight-loss diets remain popular; however, the long-term effects of these diets are not known...
Physical activity in relation to long-term weight maintenance after intentional weight loss in premenopausal womenRania A Mekary
Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts, USA
Obesity (Silver Spring) 18:167-74. 2010..Increased PA, particularly high intensity activities, is associated with better maintenance of weight loss. The benefits of activity were greater among overweight/obese than normal weight women...
Depressive symptoms and risk of type 2 diabetes in womenCassandra Arroyo
Department of Biostatistics, Harvard School of Public Health, Boston, Massachusetts, USA
Diabetes Care 27:129-33. 2004..To explore the relationship between depressive symptoms and incidence of type 2 diabetes in women...
Blood concentrations of individual long-chain n-3 fatty acids and risk of nonfatal myocardial infarctionQi Sun
Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
Am J Clin Nutr 88:216-23. 2008..Whereas dietary intake of long-chain n-3 fatty acids has been associated with risk of nonfatal myocardial infarction (MI), few studies have examined the relation for blood concentrations...
Biomarkers of endothelial dysfunction and risk of type 2 diabetes mellitusJames B Meigs
General Medicine Division, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, Mass 02114, USA
JAMA 291:1978-86. 2004..Endothelial dysfunction occurs in diagnosed type 2 diabetes mellitus but may also precede development of diabetes...
Bidirectional association between depression and type 2 diabetes mellitus in womenAn Pan
Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
Arch Intern Med 170:1884-91. 2010..Although it has been hypothesized that the diabetes-depression relation is bidirectional, few studies have addressed this hypothesis in a prospective setting...
Coffee consumption and markers of inflammation and endothelial dysfunction in healthy and diabetic womenEsther Lopez-Garcia
Department of Nutrition and Epidemiology, Harvard Medical School, Boston, MA, USA
Am J Clin Nutr 84:888-93. 2006..In several short-term studies, coffee consumption has been associated with impairment of endothelial function...
Soluble intercellular adhesion molecules, soluble vascular cell adhesion molecules, and risk of coronary heart diseaseIris Shai
Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA
Obesity (Silver Spring) 14:2099-106. 2006....
Obesity as compared with physical activity in predicting risk of coronary heart disease in womenTricia Y Li
Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
Circulation 113:499-506. 2006..CONCLUSIONS: Obesity and physical inactivity independently contribute to the development of CHD in women. These data underscore the importance of both maintaining a healthy weight and regular physical activity in preventing CHD...
