A G Herzog

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. ncbi request reprint Altered reproductive endocrine regulation in men with epilepsy: implications for reproductive function and seizures
    Andrew G Herzog
    Ann Neurol 51:539-42. 2002
  2. ncbi request reprint Reproductive endocrine considerations and hormonal therapy for men with epilepsy
    A G Herzog
    Neuroendocrine Unit, Charles A Dana Research Institute, Beth Israel Hospital, Boston, MA 02215
    Epilepsia 32:S34-7. 1991
  3. ncbi request reprint Is there a lateralized asymmetry in the sensitivity of the brain to hormones in epilepsy?
    Andrew G Herzog
    Epilepsy Behav 11:157-9. 2007
  4. ncbi request reprint Differential effects of antiepileptic drugs on neuroactive steroids in men with epilepsy
    Andrew G Herzog
    Harvard Neuroendocrine Unit, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02215, USA
    Epilepsia 47:1945-8. 2006
  5. ncbi request reprint Hormone replacement therapy in women with epilepsy: a randomized, double-blind, placebo-controlled study
    Cynthia L Harden
    Comprehensive Epilepsy Center, Department of Neurology and Neuroscience, Weill Medical College of Cornell University, New York, NY 10021, USA
    Epilepsia 47:1447-51. 2006
  6. pmc Progesterone vs placebo therapy for women with epilepsy: A randomized clinical trial
    A G Herzog
    Harvard Neuroendocrine Unit, Beth Israel Deaconess Medical Center, Boston, MA, USA
    Neurology 78:1959-66. 2012
  7. ncbi request reprint Menstrual disorders in women with epilepsy
    Andrew G Herzog
    Harvard Neuroendocrine Unit, Beth Israel Deaconess Medical Center, Wellesley, MA 02481, USA
    Neurology 66:S23-8. 2006
  8. ncbi request reprint Differential effects of antiepileptic drugs on sexual function and hormones in men with epilepsy
    A G Herzog
    Harvard Neuroendocrine Unit, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
    Neurology 65:1016-20. 2005
  9. ncbi request reprint Serum valproate levels with oral contraceptive use
    Andrew G Herzog
    Harvard Neuroendocrine Unit, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA
    Epilepsia 46:970-1. 2005
  10. doi request reprint Catamenial epilepsy: definition, prevalence pathophysiology and treatment
    Andrew G Herzog
    Harvard Medical School, Harvard Neuroendocrine Unit, Beth Israel Deaconess Medical Center, 330 Brookline Avenue, Boston, MA 02215, USA
    Seizure 17:151-9. 2008

Research Grants

  1. PROGESTERONE THERAPY FOR WOMEN WITH EPILEPSY
    Andrew Herzog; Fiscal Year: 2002
  2. PROGESTERONE THERAPY FOR WOMEN WITH EPILEPSY
    Andrew Herzog; Fiscal Year: 2000
  3. PROGESTERONE THERAPY FOR WOMEN WITH EPILEPSY
    Andrew Herzog; Fiscal Year: 2001
  4. PROGESTERONE THERAPY FOR WOMEN WITH EPILEPSY
    Andrew Herzog; Fiscal Year: 2005
  5. PROGESTERONE THERAPY FOR WOMEN WITH EPILEPSY
    Andrew Herzog; Fiscal Year: 2006
  6. PROGESTERONE THERAPY FOR WOMEN WITH EPILEPSY
    Andrew Herzog; Fiscal Year: 2007

Detail Information

Publications30

  1. ncbi request reprint Altered reproductive endocrine regulation in men with epilepsy: implications for reproductive function and seizures
    Andrew G Herzog
    Ann Neurol 51:539-42. 2002
  2. ncbi request reprint Reproductive endocrine considerations and hormonal therapy for men with epilepsy
    A G Herzog
    Neuroendocrine Unit, Charles A Dana Research Institute, Beth Israel Hospital, Boston, MA 02215
    Epilepsia 32:S34-7. 1991
    ..This possibility is supported by the improved seizure control achieved with the adjunctive use of the aromatase inhibitor testolactone or the antiestrogen clomiphene...
  3. ncbi request reprint Is there a lateralized asymmetry in the sensitivity of the brain to hormones in epilepsy?
    Andrew G Herzog
    Epilepsy Behav 11:157-9. 2007
  4. ncbi request reprint Differential effects of antiepileptic drugs on neuroactive steroids in men with epilepsy
    Andrew G Herzog
    Harvard Neuroendocrine Unit, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02215, USA
    Epilepsia 47:1945-8. 2006
    ..To compare serum levels of neuroactive steroids among men with epilepsy who take various antiepileptic drugs, untreated men with epilepsy and normal controls (NC)...
  5. ncbi request reprint Hormone replacement therapy in women with epilepsy: a randomized, double-blind, placebo-controlled study
    Cynthia L Harden
    Comprehensive Epilepsy Center, Department of Neurology and Neuroscience, Weill Medical College of Cornell University, New York, NY 10021, USA
    Epilepsia 47:1447-51. 2006
    ..We sought to determine whether adding HRT to the medication regimen of postmenopausal women with epilepsy was associated with an increase in seizure frequency...
  6. pmc Progesterone vs placebo therapy for women with epilepsy: A randomized clinical trial
    A G Herzog
    Harvard Neuroendocrine Unit, Beth Israel Deaconess Medical Center, Boston, MA, USA
    Neurology 78:1959-66. 2012
    ..To assess progesterone treatment of intractable seizures in women with partial epilepsy...
  7. ncbi request reprint Menstrual disorders in women with epilepsy
    Andrew G Herzog
    Harvard Neuroendocrine Unit, Beth Israel Deaconess Medical Center, Wellesley, MA 02481, USA
    Neurology 66:S23-8. 2006
    ..The intricate relationship between reproductive disorders and epilepsy suggests that reproductive function should be monitored closely as part of the comprehensive care of women with epilepsy...
  8. ncbi request reprint Differential effects of antiepileptic drugs on sexual function and hormones in men with epilepsy
    A G Herzog
    Harvard Neuroendocrine Unit, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
    Neurology 65:1016-20. 2005
    ..To compare sexual function and reproductive hormone levels among men with epilepsy who took various antiepileptic drugs (AEDs), untreated men with epilepsy, and normal controls...
  9. ncbi request reprint Serum valproate levels with oral contraceptive use
    Andrew G Herzog
    Harvard Neuroendocrine Unit, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA
    Epilepsia 46:970-1. 2005
  10. doi request reprint Catamenial epilepsy: definition, prevalence pathophysiology and treatment
    Andrew G Herzog
    Harvard Medical School, Harvard Neuroendocrine Unit, Beth Israel Deaconess Medical Center, 330 Brookline Avenue, Boston, MA 02215, USA
    Seizure 17:151-9. 2008
    ..Prospective, randomized, placebo-controlled, double-blind investigations are warranted and under way...
  11. doi request reprint Disorders of reproduction in patients with epilepsy: primary neurological mechanisms
    Andrew G Herzog
    Harvard Medical School, Neuroendocrine Unit, Beth Israel Deaconess Medical Center, 330 Brookline Avenue, Boston, MA 02215, USA
    Seizure 17:101-10. 2008
    ..The significance of these reproductive endocrine disorders is that they may contribute not only to sexual dysfunction and infertility but may also have an adverse impact on seizure control...
  12. doi request reprint Sensitivity and specificity of the association between catamenial seizure patterns and ovulation
    Andrew G Herzog
    Harvard Neuroendocrine Unit, Beth Israel Deaconess Medical Center, 330 Brookline Avenue, Boston, MA 02215, USA
    Neurology 70:486-7. 2008
  13. ncbi request reprint Differential effects of antiepileptic drugs on sexual function and reproductive hormones in men with epilepsy: interim analysis of a comparison between lamotrigine and enzyme-inducing antiepileptic drugs
    Andrew G Herzog
    Harvard Neuroendocrine Unit, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02215, USA
    Epilepsia 45:764-8. 2004
    ..We compared sexual function and reproductive hormone levels among men with localization-related epilepsy (LRE) taking various antiepileptic drugs (AEDs) and normal controls (NC)...
  14. ncbi request reprint Paired-pulse transcranial magnetic stimulation: effects of hemispheric laterality, gender, and handedness in normal controls
    Seth D Cahn
    Laboratory for Magnetic Brain Stimulation, Behavioral Neurology, Neurology Department, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02215, USA
    J Clin Neurophysiol 20:371-4. 2003
    ....
  15. doi request reprint Valproate and lamotrigine level variation with menstrual cycle phase and oral contraceptive use
    A G Herzog
    Harvard Neuroendocrine Unit, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
    Neurology 72:911-4. 2009
    ....
  16. doi request reprint Hormonal therapies: progesterone
    Andrew G Herzog
    Harvard Neuroendocrine Unit, Beth Israel Deaconess Medical Center, Wellesley, Massachusetts 02481, USA
    Neurotherapeutics 6:383-91. 2009
    ..If hormones play a role in seizure occurrence, hormones may also have a role in treatment. Progesterone has potent GABAergic metabolites that may provide safe and effective seizure control in women who have catamenial epilepsy...
  17. doi request reprint A comparison of anastrozole and testosterone versus placebo and testosterone for treatment of sexual dysfunction in men with epilepsy and hypogonadism
    Andrew G Herzog
    Harvard Neuroendocrine Unit, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
    Epilepsy Behav 17:264-71. 2010
    ....
  18. ncbi request reprint Premenstrual dysphoric disorder in women with epilepsy: relationships to potential epileptic, antiepileptic drug, and reproductive endocrine factors
    Andrew G Herzog
    Harvard Neuroendocrine Unit, Beth Israel Deaconess Medical Center, Boston, MA, USA
    Epilepsy Behav 21:391-6. 2011
    ..PMDD severity scores may correlate directly with carbamazepine levels, whereas they correlate inversely with lamotrigine levels...
  19. doi request reprint Variation of seizure frequency with ovulatory status of menstrual cycles
    Andrew G Herzog
    Harvard Neuroendocrine Unit, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA
    Epilepsia 52:1843-8. 2011
    ..To determine if seizure frequency differs between anovulatory and ovulatory cycles...
  20. ncbi request reprint Testosterone versus testosterone and testolactone in treating reproductive and sexual dysfunction in men with epilepsy and hypogonadism
    A G Herzog
    Harvard Neuroendocrine Unit, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
    Neurology 50:782-4. 1998
    ..Treatment using a combination of testosterone and the aromatase inhibitor testolactone may have significantly better effects on sexual function and also seizure frequency than testosterone alone...
  21. ncbi request reprint Menstrual cycle interval and ovulation in women with localization-related epilepsy
    A G Herzog
    Harvard Neuroendocrine Unit, Beth Israel Deaconess Medical Center, Boston, MA 02115, USA
    Neurology 57:2133-5. 2001
    ..Groups B and C also had significantly higher estradiol/progesterone ratios than Group A. Nevertheless, almost one-half (46.2%) of the anovulatory cycles occurred in women with normal 26-32 day cycles...
  22. ncbi request reprint Sexual hormones and epilepsy: threat and opportunities
    Andrew G Herzog
    Harvard Neuroendocrine Unit, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02215, USA
    Curr Opin Neurol 18:167-72. 2005
    ..This article reviews recent developments in our knowledge of the reciprocal interactions between epilepsy and sex hormones and how these interactions may play a role in the pathophysiology and treatment of both...
  23. ncbi request reprint Relationship of sexual dysfunction to epilepsy laterality and reproductive hormone levels in women
    Andrew G Herzog
    Harvard Neuroendocrine Unit, Beth Israel Deaconess Medical Center, 330 Brookline Avenue, Boston, MA 02215, USA
    Epilepsy Behav 4:407-13. 2003
    ..The value of hormonal replacement or supplementation remains to be explored...
  24. ncbi request reprint Interictal EEG discharges, reproductive hormones, and menstrual disorders in epilepsy
    Andrew G Herzog
    Harvard Neuroendocrine Unit, Beth Israel Deaconess Medical Center, 330 Brooklione Avenue, Boston, MA 02215, USA
    Ann Neurol 54:625-37. 2003
    ..There are notable differences between enzyme-inducing and noninducing drugs. Menstrual disorders are more common among women with interictal discharges as well as women with abnormal hormonal findings...
  25. ncbi request reprint Frequency of catamenial seizure exacerbation in women with localization-related epilepsy
    Andrew G Herzog
    Harvard Neuroendocrine Unit, Beth Israel Deaconess Medical Center, Boston, MA 02215
    Ann Neurol 56:431-4. 2004
    ..Among anovulatory cycles, average daily seizure frequency was substantially less during the midfollicular phase than during the remainder of the cycle. Overall, 39.1% of the women had catamenial epilepsy...
  26. ncbi request reprint Seizure exacerbation associated with inhibition of progesterone metabolism
    Andrew G Herzog
    Harvard Neuroendocrine Unit, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
    Ann Neurol 53:390-1. 2003
    ..We report a case in which efficacy was eliminated during concomitant treatment with a reductase inhibitor. The observation suggests that a reduced metabolite, rather than progesterone itself, was responsible for improved seizure control...
  27. pmc Sleep spindle alterations in patients with malformations of cortical development
    Megan F Selvitelli
    Comprehensive Epilepsy Center, Department of Neurology, Beth Israel Deaconess Medical Center and Harvard Medical School, 330 Brookline Avenue, Boston, MA 02215, USA
    Brain Dev 31:163-8. 2009
    ..Our findings suggest that brain malformations disrupt the thalamocortical circuits responsible for sleep spindle generation, and support the need for further studies on the relationships between cortical maldevelopment and sleep...
  28. ncbi request reprint Neuroactive properties of reproductive steroids
    Andrew G Herzog
    Harvard Medical School, Harvard Neuroendocrine Unit, Beth Israel Deaconess Medical Center, Boston, MA, USA
    Headache 47:S68-78. 2007
    ..Estrogen stabilization may provide effective treatment in susceptible women, especially for catamenially exacerbated migraine...
  29. ncbi request reprint Circalunar and ultralunar periodicities in women with partial seizures
    Mark Quigg
    Department of Neurology, University of Virginia, Charlottesville, Virginia 22908, USA
    Epilepsia 49:1081-5. 2008
    ..In the present study, we determined seizure periodicity according to a "menstrual clock" provided by a common phase marker of the onset of menses...
  30. ncbi request reprint Effect of antiepileptic drugs on reproductive endocrine function in individuals with epilepsy
    Jouko I T Isojarvi
    Department of Neurology, University of Oulu, Oulu, Finland
    CNS Drugs 19:207-23. 2005
    ..The endocrine effects of the new AEDs have not been widely studied. However, it seems they may offer an alternative if reproductive endocrine problems emerge during treatment with the older AEDs...

Research Grants7

  1. PROGESTERONE THERAPY FOR WOMEN WITH EPILEPSY
    Andrew Herzog; Fiscal Year: 2002
    ..30 x .35) 100,000 women with catamenial epilepsy and perhaps many more women with no a priori demonstrated hormonal sensitivity to seizure occurrence. ..
  2. PROGESTERONE THERAPY FOR WOMEN WITH EPILEPSY
    Andrew Herzog; Fiscal Year: 2000
    ..30 x .35) 100,000 women with catamenial epilepsy and perhaps many more women with no a priori demonstrated hormonal sensitivity to seizure occurrence. ..
  3. PROGESTERONE THERAPY FOR WOMEN WITH EPILEPSY
    Andrew Herzog; Fiscal Year: 2001
    ..30 x .35) 100,000 women with catamenial epilepsy and perhaps many more women with no a priori demonstrated hormonal sensitivity to seizure occurrence. ..
  4. PROGESTERONE THERAPY FOR WOMEN WITH EPILEPSY
    Andrew Herzog; Fiscal Year: 2005
    ..30 x .35) 100,000 women with catamenial epilepsy and perhaps many more women with no a priori demonstrated hormonal sensitivity to seizure occurrence. ..
  5. PROGESTERONE THERAPY FOR WOMEN WITH EPILEPSY
    Andrew Herzog; Fiscal Year: 2006
    ..30 x .35) 100,000 women with catamenial epilepsy and perhaps many more women with no a priori demonstrated hormonal sensitivity to seizure occurrence. ..
  6. PROGESTERONE THERAPY FOR WOMEN WITH EPILEPSY
    Andrew Herzog; Fiscal Year: 2007
    ..30 x .35) 100,000 women with catamenial epilepsy and perhaps many more women with no a priori demonstrated hormonal sensitivity to seizure occurrence. ..