S Hernandez-Diaz

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. ncbi request reprint Alteration of bioelectrically-controlled processes in the embryo: a teratogenic mechanism for anticonvulsants
    Sonia Hernandez-Diaz
    Department of Epidemiology, Harvard School of Public Health, Boston, MA, United States Electronic address
    Reprod Toxicol 47:111-4. 2014
  2. pmc Risk of pre-eclampsia in first and subsequent pregnancies: prospective cohort study
    Sonia Hernandez-Diaz
    Department of Epidemiology, Harvard School of Public Health, 677 Huntington Ave, Boston, MA 02115, USA
    BMJ 338:b2255. 2009
  3. ncbi request reprint Risk of complications after a peptic ulcer diagnosis: effectiveness of proton pump inhibitors
    Sonia Hernandez-Diaz
    Department of Epidemiology, Harvard School of Public Health, 677 Huntington Avenue, Boston, MA 02115, USA
    Dig Dis Sci 58:1653-62. 2013
  4. doi request reprint Comparative safety of antiepileptic drugs during pregnancy
    S Hernandez-Diaz
    Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA
    Neurology 78:1692-9. 2012
  5. pmc Cardioprotective aspirin users and their excess risk of upper gastrointestinal complications
    Sonia Hernandez-Diaz
    Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA
    BMC Med 4:22. 2006
  6. ncbi request reprint Nonsteroidal anti-inflammatory drugs and risk of lung cancer
    Sonia Hernandez-Diaz
    Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
    Int J Cancer 120:1565-72. 2007
  7. ncbi request reprint Association between nonsteroidal anti-inflammatory drugs and upper gastrointestinal tract bleeding/perforation: an overview of epidemiologic studies published in the 1990s
    S Hernandez-Diaz
    Department of Epidemiology, Harvard School of Public Health, 677 Huntington Ave, Boston, MA 02115, USA
    Arch Intern Med 160:2093-9. 2000
  8. pmc From causal diagrams to birth weight-specific curves of infant mortality
    Sonia Hernandez-Diaz
    Department of Epidemiology, Harvard School of Public Health, 677 Huntington Avenue, Boston, MA 02115, USA
    Eur J Epidemiol 23:163-6. 2008
  9. pmc Medications as a potential source of exposure to phthalates in the U.S. population
    Sonia Hernandez-Diaz
    Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts 02115, USA
    Environ Health Perspect 117:185-9. 2009
  10. ncbi request reprint Diabetes therapy and cancer risk: causal effects and other plausible explanations
    S Hernandez-Diaz
    Department of Epidemiology, Harvard School of Public Health, 677 Huntington Avenue, Boston, MA 02115, USA
    Diabetologia 53:802-8. 2010

Collaborators

Detail Information

Publications40

  1. ncbi request reprint Alteration of bioelectrically-controlled processes in the embryo: a teratogenic mechanism for anticonvulsants
    Sonia Hernandez-Diaz
    Department of Epidemiology, Harvard School of Public Health, Boston, MA, United States Electronic address
    Reprod Toxicol 47:111-4. 2014
    ..We propose that development of pharmaceuticals that do not alter cell resting transmembrane voltage levels could result in safer drugs. ..
  2. pmc Risk of pre-eclampsia in first and subsequent pregnancies: prospective cohort study
    Sonia Hernandez-Diaz
    Department of Epidemiology, Harvard School of Public Health, 677 Huntington Ave, Boston, MA 02115, USA
    BMJ 338:b2255. 2009
    ..To investigate whether pre-eclampsia is more common in first pregnancies solely because fewer affected women, who presumably have a higher risk of recurrence, go on to have subsequent pregnancies...
  3. ncbi request reprint Risk of complications after a peptic ulcer diagnosis: effectiveness of proton pump inhibitors
    Sonia Hernandez-Diaz
    Department of Epidemiology, Harvard School of Public Health, 677 Huntington Avenue, Boston, MA 02115, USA
    Dig Dis Sci 58:1653-62. 2013
    ..e., a clear indication. To minimize selection bias we mimicked an intention to treat approach by assessing the effect of PPI prescription after PU diagnosis...
  4. doi request reprint Comparative safety of antiepileptic drugs during pregnancy
    S Hernandez-Diaz
    Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA
    Neurology 78:1692-9. 2012
    ..To assess the safety of the newer antiepileptic drugs (AEDs) during pregnancy...
  5. pmc Cardioprotective aspirin users and their excess risk of upper gastrointestinal complications
    Sonia Hernandez-Diaz
    Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA
    BMC Med 4:22. 2006
    ....
  6. ncbi request reprint Nonsteroidal anti-inflammatory drugs and risk of lung cancer
    Sonia Hernandez-Diaz
    Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
    Int J Cancer 120:1565-72. 2007
    ..34) for aspirin. In conclusion, prescription of non-aspirin NSAIDs for at least 1 year might be associated with a slightly reduced risk of lung cancer. Aspirin was not associated with a risk reduction, perhaps due to residual confounding...
  7. ncbi request reprint Association between nonsteroidal anti-inflammatory drugs and upper gastrointestinal tract bleeding/perforation: an overview of epidemiologic studies published in the 1990s
    S Hernandez-Diaz
    Department of Epidemiology, Harvard School of Public Health, 677 Huntington Ave, Boston, MA 02115, USA
    Arch Intern Med 160:2093-9. 2000
    ..Later analyses have also included the effect of patterns of NSAID use, risk factors for UGIB, and modifiers of NSAID effect...
  8. pmc From causal diagrams to birth weight-specific curves of infant mortality
    Sonia Hernandez-Diaz
    Department of Epidemiology, Harvard School of Public Health, 677 Huntington Avenue, Boston, MA 02115, USA
    Eur J Epidemiol 23:163-6. 2008
    ..Taken together, these two approaches can facilitate discussion of underlying biological mechanisms...
  9. pmc Medications as a potential source of exposure to phthalates in the U.S. population
    Sonia Hernandez-Diaz
    Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts 02115, USA
    Environ Health Perspect 117:185-9. 2009
    ..Underappreciated sources of exposure include phthalates in the polymers coating some oral medications...
  10. ncbi request reprint Diabetes therapy and cancer risk: causal effects and other plausible explanations
    S Hernandez-Diaz
    Department of Epidemiology, Harvard School of Public Health, 677 Huntington Avenue, Boston, MA 02115, USA
    Diabetologia 53:802-8. 2010
    ..However, the potential dose effect of insulin overall, and insulin glargine in particular, on colon and breast cancer deserves further attention...
  11. ncbi request reprint The birth weight "paradox" uncovered?
    Sonia Hernandez-Diaz
    Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
    Am J Epidemiol 164:1115-20. 2006
    ..An appropriate justification for conditioning on birth weight requires specifying 1) the causal question motivating this analytical approach and 2) the assumptions regarding the proposed underlying biologic mechanisms...
  12. ncbi request reprint Non-steroidal antiinflammatory drugs and the risk of acute myocardial infarction
    Sonia Hernandez-Diaz
    Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
    Basic Clin Pharmacol Toxicol 98:266-74. 2006
    ..There was a suggestion of a small increased risk with ibuprofen. Also, data suggest a small reduced risk for naproxen present only in non-users of aspirin, mainly people free of clinically apparent vascular disease...
  13. ncbi request reprint Steroids and risk of upper gastrointestinal complications
    S Hernandez-Diaz
    Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
    Am J Epidemiol 153:1089-93. 2001
    ..0) and 12.7 (95% CI: 6.2, 26.1), compared with users of none. Whenever possible, antiinflammatory drugs should be given in monotherapy and at the lowest effective dose in order to reduce the risk of upper gastrointestinal complications...
  14. ncbi request reprint Uncomplicated peptic ulcer in the UK: trends from 1997 to 2005
    S Cai
    Epidemiology Department, Harvard School of Public Health, Boston, MA 02115, USA
    Aliment Pharmacol Ther 30:1039-48. 2009
    ..Few studies have examined the incidence of uncomplicated peptic ulcer or the trends in factors affecting its incidence...
  15. ncbi request reprint Dietary folate and the risk of nonfatal myocardial infarction
    Sonia Hernandez-Diaz
    Slone Epidemiology Center, Boston University School of Public Health, Boston, MA 02215, USA
    Epidemiology 13:700-6. 2002
    ..Because folate intake can reduce homocysteine levels, we investigated the association between dietary folate intake and nonfatal myocardial infarction...
  16. ncbi request reprint Methylenetetrahydrofolate reductase polymorphisms and the risk of gestational hypertension
    Sonia Hernandez-Diaz
    Slone Epidemiology Center, Boston University School of Public Health, Boston, MA, USA
    Epidemiology 16:628-34. 2005
    ..It is also unknown whether the fetal genotype is relevant, or whether folic acid supplementation modifies this association...
  17. ncbi request reprint First-trimester use of selective serotonin-reuptake inhibitors and the risk of birth defects
    Carol Louik
    Slone Epidemiology Center at Boston University, Boston, MA 02215, USA
    N Engl J Med 356:2675-83. 2007
    ..The risk of birth defects after antenatal exposure to selective serotonin-reuptake inhibitors (SSRIs) remains controversial...
  18. doi request reprint Positive predictive value of computerized medical records for uncomplicated and complicated upper gastrointestinal ulcer
    Andrea V Margulis
    Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
    Pharmacoepidemiol Drug Saf 18:900-9. 2009
    ..We assessed the PPV of diagnosis codes in THIN, a primary-care medical-record database, to ascertain individuals with uncomplicated PU, and to identify UGIC and Helicobacter pylori infection status (HPIS) among these patients...
  19. pmc Antidepressant use during pregnancy and the risk of preterm delivery and fetal growth restriction
    Sengwee Toh
    Department of Population Medicine, Harvard Medical School Harvard Pilgrim Health Care Institute, 133 Brookline Ave 6th Floor, Boston, MA 02215, USA
    J Clin Psychopharmacol 29:555-60. 2009
    ..The associations between prenatal exposure to antidepressants and preterm delivery and fetal growth restriction are controversial and poorly understood. We studied the relation between antidepressant use and these outcomes...
  20. pmc Case-only gene-environment interaction studies: when does association imply mechanistic interaction?
    Tyler J VanderWeele
    Harvard School of Public Health, Departments of Epidemiology and Biostatistics, 677 Huntington Avenue, Boston, MA 02115, USA
    Genet Epidemiol 34:327-34. 2010
    ..We furthermore show these tests for mechanistic interaction can be extended to scenarios in which the genetic and environmental factors are negatively associated in the population rather than independent...
  21. ncbi request reprint Tetanus vaccination and risk of multiple sclerosis: a systematic review
    Miguel A Hernán
    Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
    Neurology 67:212-5. 2006
    ..To conduct a systematic review on the association between tetanus vaccination and the risk of multiple sclerosis (MS)...
  22. pmc Estimating absolute risks in the presence of nonadherence: an application to a follow-up study with baseline randomization
    Sengwee Toh
    Department of Epidemiology, Harvard School of Public Health, Boston, MA 02215, USA
    Epidemiology 21:528-39. 2010
    ..64; 95% CI = 1.24 to 2.18). The methods described here are also applicable to observational studies with time-varying treatments...
  23. pmc Asthma in pregnancy and its pharmacologic treatment
    Carol Louik
    Slone Epidemiology Center at Boston University, Boston, Massachusetts 02215, USA
    Ann Allergy Asthma Immunol 105:110-7. 2010
    ..Asthma is among the most common serious medical problems in pregnancy, and its prevalence may be increasing. Management is problematic because asthma may harm the fetus, yet little is known about fetal risks of asthma medications...
  24. ncbi request reprint Causal knowledge as a prerequisite for confounding evaluation: an application to birth defects epidemiology
    Miguel A Hernán
    Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
    Am J Epidemiol 155:176-84. 2002
    ..65 (95% confidence interval: 0.46, 0.94) should be used because the adjusted odds ratio is invalid. Causal diagrams are used to encode qualitative a priori subject matter knowledge...
  25. ncbi request reprint A structural approach to selection bias
    Miguel A Hernán
    Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts 02115, USA
    Epidemiology 15:615-25. 2004
    ..This classification also leads to a unified approach to adjust for selection bias...
  26. pmc Selective serotonin reuptake inhibitor use and risk of gestational hypertension
    Sengwee Toh
    Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
    Am J Psychiatry 166:320-8. 2009
    ..The purpose of this study was to assess the effects of treatment with selective serotonin reuptake inhibitors (SSRIs) on the risks of gestational hypertension and preeclampsia...
  27. ncbi request reprint Antibiotic use and the risk of lung cancer
    Hui Zhang
    Department Epidemiology, Harvard School of Public Health, 677 Huntington Avenue, Boston, MA 02115, USA
    Cancer Epidemiol Biomarkers Prev 17:1308-15. 2008
    ..Current evidence is insufficient to support or refute a carcinogenic effect of antibiotics...
  28. ncbi request reprint Statins and fracture risk. A systematic review
    Sengwee Toh
    Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA
    Pharmacoepidemiol Drug Saf 16:627-40. 2007
    ..To summarize current evidence on statin use and fracture risk and to explore potential sources of heterogeneity among study results...
  29. doi request reprint Sensitivity and specificity of computerized algorithms to classify gestational periods in the absence of information on date of conception
    Sengwee Toh
    Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
    Am J Epidemiol 167:633-40. 2008
    ..However, the sensitivity of this algorithm is lower for preterm deliveries, suggesting limited validity to assess drug safety for pregnancy outcomes associated with prematurity...
  30. ncbi request reprint Use of antidepressants and risk of lung cancer
    Sengwee Toh
    Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
    Cancer Causes Control 18:1055-64. 2007
    ..To evaluate the effect of antidepressant use on lung cancer risk...
  31. ncbi request reprint Pharmacoepidemiology and rheumatic disorders
    K Arnold Chan
    Department of Epidemiology, Harvard School of Public Health, 677 Huntington Avenue, Boston, MA 02115, USA
    Rheum Dis Clin North Am 30:835-50, vii. 2004
    ....
  32. ncbi request reprint Trends and predictors of folic acid awareness and periconceptional use in pregnant women
    Lolkje T W de Jong-van den Berg
    Slone Epidemiology Center, Boston University School of Public Health, Boston, Mass, USA
    Am J Obstet Gynecol 192:121-8. 2005
    ..The purpose of this study was to describe recent trends in folic acid awareness and use in the periconceptional period among pregnant women in relation to maternal sociodemographic and other relevant factors...
  33. pmc Gestational hypertension in pregnancies supported by infertility treatments: role of infertility, treatments, and multiple gestations
    Sonia Hernandez-Diaz
    Slone Epidemiology Center at Boston University, Boston, Massachusetts 02215, USA
    Fertil Steril 88:438-45. 2007
    ..To investigate the association between infertility treatments and gestational hypertension and preeclampsia...
  34. ncbi request reprint Smoking and the risk of oral clefts: exploring the impact of study designs
    Katie A Meyer
    Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA
    Epidemiology 15:671-8. 2004
    ..We used case-crossover, case-time-control, and bidirectional case-crossover designs to supplement findings from a case-control study of maternal smoking and oral clefts among offspring in a large birth registry...
  35. pmc Outpatient calcium-channel blockers and the risk of postpartum haemorrhage: a cohort study
    B T Bateman
    Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA, USA Department of Anesthesiology, Critical Care, and Pain Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA
    BJOG 120:1668-76; dicussion 1676-7. 2013
    ..To determine whether outpatient exposure to calcium-channel blockers (CCBs) at the time of delivery is associated with an increased risk for postpartum haemorrhage (PPH)...
  36. ncbi request reprint Case-crossover and case-time-control designs in birth defects epidemiology
    Sonia Hernandez-Diaz
    Slone Epidemiology Center, Boston University School of Public Health, 1010 Commonwealth Avenue, Boston, MA 02215, USA
    Am J Epidemiol 158:385-91. 2003
    ..9 (95% CI: 1.2, 7.2), but it requires controls. In the presence of gestational time trends of exposure, the new designs do not offer clear advantages over the case-control design...
  37. ncbi request reprint Nausea and vomiting in pregnancy: maternal characteristics and risk factors
    Carol Louik
    Slone Epidemiology Centre, Boston University, MA 02115, USA
    Paediatr Perinat Epidemiol 20:270-8. 2006
    ..Together with selected demographic characteristics that differentiate early- vs. late-onset NVP, these findings warrant further investigation...
  38. ncbi request reprint Risk factors for persistent pulmonary hypertension of the newborn
    Sonia Hernandez-Diaz
    Slone Epidemiology Center at Boston University, 1010 Commonwealth Ave, Boston, MA 02215, USA
    Pediatrics 120:e272-82. 2007
    ..We performed a case-control study to determine possible antenatal and perinatal predictors of persistent pulmonary hypertension of the newborn...
  39. pmc Endotoxin-directed innate immunity in tracheal aspirates of mechanically ventilated human neonates
    Katheryn E Nathe
    Department of Medicine, Children s Hospital Boston, Boston, Massachusetts 02115, USA
    Pediatr Res 66:191-6. 2009
    ..TA extracellular BPI, LBP, and sCD14 were positively correlated. TAs from intubated neonates demonstrate endotoxin accumulation and mobilization of endotoxin-directed innate immunity, potentially contributing to pulmonary inflammation...
  40. ncbi request reprint Use of over-the-counter medications during pregnancy
    Martha M Werler
    Slone Epidemiology Center at Boston University, Boston, MA, USA
    Am J Obstet Gynecol 193:771-7. 2005
    ..We describe the patterns of over-the-counter medication use among pregnant women...

Research Grants6

  1. Phthalates in Drugs and Male Genital Malformation
    Sonia Hernandez diaz; Fiscal Year: 2009
    ....
  2. Assessment of Infant Outcomes After in Utero Exposure to Antiretroviral Therapy
    Sonia Hernandez diaz; Fiscal Year: 2009
    ..We propose to evaluate the risk of congenital malformations and other adverse pregnancy outcomes following antenatal exposure to ART in a prospective cohort of pregnant women. ..
  3. Comparative Effectiveness and Safety of Depression Treatments during Pregnancy
    Sonia Hernandez diaz; Fiscal Year: 2009
    ....
  4. Assessment of Infant Outcomes After in Utero Exposure to Antiretroviral Therapy
    Sonia Hernandez diaz; Fiscal Year: 2010
    ..We propose to evaluate the risk of congenital malformations and other adverse pregnancy outcomes following antenatal exposure to ART in a prospective cohort of pregnant women. ..
  5. Phthalates in Drugs and Male Genital Malformation
    Allen A Mitchell; Fiscal Year: 2010
    ....
  6. Comparative Effectiveness and Safety of Depression Treatments during Pregnancy
    Sonia Hernandez diaz; Fiscal Year: 2010
    ....