Research Topics
| Trey HeddenSummaryAffiliation: Harvard University Country: USA Publications
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Detail Information
Publications
Cognitive profile of amyloid burden and white matter hyperintensities in cognitively normal older adultsTrey Hedden
Athinoula A Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, Massachusetts 02129, USA
J Neurosci 32:16233-42. 2012..These findings suggest that even before clinical impairment, amyloid burden and WMH likely represent neuropathological cascades with distinct etiologies and dissociable influences on cognition...- Failure to modulate attentional control in advanced aging linked to white matter pathologyTrey Hedden
Athinoula A Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, MA 02129, USA
Cereb Cortex 22:1038-51. 2012..These results suggest failure to modulate frontal and parietal activity reflects a disruptive process in advanced aging associated with specific neuropathologic processes... - Shared and selective neural correlates of inhibition, facilitation, and shifting processes during executive controlTrey Hedden
Psychology Department, Stanford University, USA
Neuroimage 51:421-31. 2010..Several of these common regions were also involved during facilitation, suggesting that they are responsive to the number of task-salient channels of information, rather than purely to demands on control processes... - Disruption of functional connectivity in clinically normal older adults harboring amyloid burdenTrey Hedden
Athinoula A Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA 02129, USA
J Neurosci 29:12686-94. 2009.... - Amyloid-β associated cortical thinning in clinically normal elderlyJ Alex Becker
Department of Radiology, Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
Ann Neurol 69:1032-42. 2011.... 
Healthy and pathological processes in adult development: new evidence from neuroimaging of the aging brainTrey Hedden
Stanford University, Stanford, California, Cambridge, Massachusetts, USA
Curr Opin Neurol 18:740-7. 2005..These variations in cognitive aging can be related to their neural bases via structural and functional neuroimaging methods...- Functional alterations in memory networks in early Alzheimer's diseaseReisa A Sperling
Department of Neurology, Center for Alzheimer s Research and Treatment, Brigham and Women s Hospital, 221 Longwood Avenue, Boston, MA 02115, USA
Neuromolecular Med 12:27-43. 2010..Research is ongoing to determine if these early network alterations will serve as sensitive predictors of clinical decline, and eventually, as markers of pharmacological response to potential disease-modifying treatments for AD... - Amyloid deposition is associated with impaired default network function in older persons without dementiaReisa A Sperling
Center for Alzheimer Research and Treatment, Department of Neurology, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
Neuron 63:178-88. 2009.... - Cortical hubs revealed by intrinsic functional connectivity: mapping, assessment of stability, and relation to Alzheimer's diseaseRandy L Buckner
Department of Psychology and Center for Brain Science, Harvard University, Cambridge, Massachusetts 02138, USA
J Neurosci 29:1860-73. 2009.... - Categorical organization in free recall across culture and ageAngela H Gutchess
Department of Psychology, University of Michigan, Ann Arbor, Mich, USA
Gerontology 52:314-23. 2006..Cross-cultural differences in cognition suggest that Westerners use categories more than Easterners, but these differences have only been investigated in young adults... - Individual differences in executive processing predict susceptibility to interference in verbal working memoryTrey Hedden
Psychology Department, Stanford University, Stanford, CA, USA
Neuropsychology 20:511-28. 2006.... - Age and amyloid-related alterations in default network habituation to stimulus repetitionPatrizia Vannini
Athinoula A Martinos Center for Biomedical Imaging, Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA, USA
Neurobiol Aging 33:1237-52. 2012.... - Insights into the ageing mind: a view from cognitive neuroscienceTrey Hedden
Stanford University, Psychology Department, 434 Jordan Hall, Building 420, Stanford, California 94305-2130, USA
Nat Rev Neurosci 5:87-96. 2004 - Evidence from intrinsic activity that asymmetry of the human brain is controlled by multiple factorsHesheng Liu
Athinoula A Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, MA 02129, USA
Proc Natl Acad Sci U S A 106:20499-503. 2009..These findings show the feasibility of measuring brain asymmetry using intrinsic activity fluctuations and suggest that multiple genetic or environmental mechanisms control cerebral lateralization... - Contributions of processing ability and knowledge to verbal memory tasks across the adult life-spanTrey Hedden
Department of Psychology, 434 Jordan Hall, Building 420, Stanford University, Stanford, CA 94305 2130, USA
Q J Exp Psychol A 58:169-90. 2005.... 
Meta-analysis of amyloid-cognition relations in cognitively normal older adultsTrey Hedden
From the Athinoula A Martinos Center for Biomedical Imaging T H, A P Y, Department of Radiology, Massachusetts General Hospital, Charlestown Departments of Radiology T H and Psychiatry A P Y, Massachusetts General Hospital, Harvard Medical School, Boston, MA and Helen Wills Neuroscience Institute H O, T A P, University of California, Berkeley, CA
Neurology 80:1341-8. 2013..We conducted a meta-analysis of relationships between amyloid burden and cognition in cognitively normal, older adult humans...