Jonathan L Hecht

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. ncbi Enhanced detection of atypical hyperplasia in endometrial polyps by PTEN expression
    Jonathan L Hecht
    Department of Pathology, Beth Israel Deaconess Medical Center, Boston 02215, Massachusetts, USA
    Appl Immunohistochem Mol Morphol 12:36-9. 2004
  2. ncbi Relationship Between Neonatal Blood Protein Concentrations and Placenta Histologic Characteristics in Extremely Low GA Newborns
    Jonathan L Hecht
    Department of Pathology, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02215, USA
    Pediatr Res 69:68-73. 2011
  3. ncbi Factors associated with small head circumference at birth among infants born before the 28th week
    Thomas F McElrath
    Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, Brigham and Women s Hospital, Boston, MA, USA
    Am J Obstet Gynecol 203:138.e1-8. 2010
  4. ncbi Antenatal antecedents of a small head circumference at age 24-months post-term equivalent in a sample of infants born before the 28th post-menstrual week
    Alan Leviton
    Department of Neurology, Children s Hospital Boston and Harvard Medical School, Boston, MA, USA
    Early Hum Dev 86:515-21. 2010
  5. ncbi Management of asymptomatic ovarian and other adnexal cysts imaged at US: Society of Radiologists in Ultrasound Consensus Conference Statement
    Deborah Levine
    Depts of Radiology, Obstetrics and Gynecology, and Pathology, Beth Israel Deaconess Medical Ctr and Harvard Medical School, Boston, MA 02215, USA
    Radiology 256:943-54. 2010
  6. ncbi Persistence after birth of systemic inflammation associated with umbilical cord inflammation
    Alan Leviton
    Department of Neurology, Children s Hospital Boston and Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, USA
    J Reprod Immunol 90:235-43. 2011
  7. ncbi Histological characteristics of singleton placentas delivered before the 28th week of gestation
    Jonathan L Hecht
    Department of Pathology, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02118, USA
    Pathology 40:372-6. 2008
  8. ncbi WT1, estrogen receptor, and progesterone receptor as markers for breast or ovarian primary sites in metastatic adenocarcinoma to body fluids
    Benjamin H Lee
    Department of Pathology, Brigham and Women's Hospital, Boston, MA 02115, USA
    Am J Clin Pathol 117:745-50. 2002
  9. ncbi OLIG2 over-expression impairs proliferation of human Down syndrome neural progenitors
    Jie Lu
    Department of Neurology, Beth Israel Deaconess Medical Center, Boston, MA 02115, USA
    Hum Mol Genet 21:2330-40. 2012
  10. ncbi Cluster analysis of placental inflammatory proteins can distinguish preeclampsia from preterm labor and premature membrane rupture in singleton deliveries less than 28 weeks of gestation
    Jessica M Faupel-Badger
    Cancer Prevention Fellowship Program, National Cancer Institute, Bethesda, MD 20892 7105, USA
    Am J Reprod Immunol 66:488-94. 2011

Detail Information

Publications55

  1. ncbi Enhanced detection of atypical hyperplasia in endometrial polyps by PTEN expression
    Jonathan L Hecht
    Department of Pathology, Beth Israel Deaconess Medical Center, Boston 02215, Massachusetts, USA
    Appl Immunohistochem Mol Morphol 12:36-9. 2004
    ..Thus, in selected cases, the loss of PTEN expression in an area of glandular crowding can highlight biologically significant lesions and afford a more definitive diagnosis...
  2. ncbi Relationship Between Neonatal Blood Protein Concentrations and Placenta Histologic Characteristics in Extremely Low GA Newborns
    Jonathan L Hecht
    Department of Pathology, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02215, USA
    Pediatr Res 69:68-73. 2011
    ..These results confirm the predictive value of placental histology for the presence or absence of elevated inflammatory response in newborns...
  3. ncbi Factors associated with small head circumference at birth among infants born before the 28th week
    Thomas F McElrath
    Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, Brigham and Women s Hospital, Boston, MA, USA
    Am J Obstet Gynecol 203:138.e1-8. 2010
    ..We sought to identify risk factors for congenital microcephaly in extremely low gestational age newborns...
  4. ncbi Antenatal antecedents of a small head circumference at age 24-months post-term equivalent in a sample of infants born before the 28th post-menstrual week
    Alan Leviton
    Department of Neurology, Children s Hospital Boston and Harvard Medical School, Boston, MA, USA
    Early Hum Dev 86:515-21. 2010
    ..Little is known about the antecedents of microcephaly in early childhood among children born at extremely low gestational age...
  5. ncbi Management of asymptomatic ovarian and other adnexal cysts imaged at US: Society of Radiologists in Ultrasound Consensus Conference Statement
    Deborah Levine
    Depts of Radiology, Obstetrics and Gynecology, and Pathology, Beth Israel Deaconess Medical Ctr and Harvard Medical School, Boston, MA 02215, USA
    Radiology 256:943-54. 2010
    ....
  6. ncbi Persistence after birth of systemic inflammation associated with umbilical cord inflammation
    Alan Leviton
    Department of Neurology, Children s Hospital Boston and Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, USA
    J Reprod Immunol 90:235-43. 2011
    ....
  7. ncbi Histological characteristics of singleton placentas delivered before the 28th week of gestation
    Jonathan L Hecht
    Department of Pathology, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02118, USA
    Pathology 40:372-6. 2008
    ..We describe the histological characteristics of 947 singleton placentas from infants born between 23 and 27 weeks gestation...
  8. ncbi WT1, estrogen receptor, and progesterone receptor as markers for breast or ovarian primary sites in metastatic adenocarcinoma to body fluids
    Benjamin H Lee
    Department of Pathology, Brigham and Women's Hospital, Boston, MA 02115, USA
    Am J Clin Pathol 117:745-50. 2002
    ..Reactivity for ER and PR did not distinguish between breast and ovarian metastases; however; studies for WTI protein and GCDFP may aid in making this distinction...
  9. ncbi OLIG2 over-expression impairs proliferation of human Down syndrome neural progenitors
    Jie Lu
    Department of Neurology, Beth Israel Deaconess Medical Center, Boston, MA 02115, USA
    Hum Mol Genet 21:2330-40. 2012
    ..These findings suggest that OLIG2 over-expression inhibits neural progenitor proliferation through changes in potassium channel activity, thereby contributing to the reduced neuronal numbers and brain size in DS...
  10. ncbi Cluster analysis of placental inflammatory proteins can distinguish preeclampsia from preterm labor and premature membrane rupture in singleton deliveries less than 28 weeks of gestation
    Jessica M Faupel-Badger
    Cancer Prevention Fellowship Program, National Cancer Institute, Bethesda, MD 20892 7105, USA
    Am J Reprod Immunol 66:488-94. 2011
    ..The risks of complications are different between iatrogenic (e.g. PE) and spontaneous (e.g. PL and membrane rupture) causes of preterm delivery, suggesting different underlying biology contributes to these placental conditions...
  11. ncbi Colonization of second-trimester placenta parenchyma
    Andrew B Onderdonk
    Department of Pathology, Brigham and Women s Hospital, Boston, MA, USA
    Am J Obstet Gynecol 199:52.e1-52.e10. 2008
    ..The overtly healthy, nonpregnant uterus harbors bacteria, Mycoplasma and Ureaplasma. The extent of colonization remains elusive, as are relationships between isolated microorganisms, preterm labor and fetal inflammation...
  12. ncbi Validation of tissue microarray technology in ovarian cancer: results from the Nurses' Health Study
    Jonathan L Hecht
    Department of Pathology, Beth Israel Deaconess Medical Center, 330 Brookline Avenue, Boston, MA 02215, USA
    Cancer Epidemiol Biomarkers Prev 17:3043-50. 2008
    ..Tissue microarrays (TMAs) allow high-throughput evaluation of protein expression from archived tissue samples. We identified characteristics specific to ovarian cancer that may influence TMA interpretation...
  13. ncbi Patterns of misinterpretation of adnexal masses on CT and MR in an academic radiology department
    Elizabeth Asch
    Harvard Medical School, Boston, MA, USA
    Acad Radiol 16:969-80. 2009
    ..The aim of this study was to assess potential quality assurance (QA) issues in the diagnosis and characterization of adnexal masses on pelvic computed tomographic (CT) and magnetic resonance (MR) imaging studies...
  14. ncbi Relationship between dietary and supplemental intake of folate, methionine, vitamin B6 and folate receptor alpha expression in ovarian tumors
    Joanne Kotsopoulos
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA
    Int J Cancer 126:2191-8. 2010
    ..Our data do not support the hypothesis that the relationship between factors involved in one-carbon metabolism and ovarian cancer risk differs by FRalpha status of the tumor...
  15. ncbi Monoclonal antibody MOC-31 reactivity as a marker for adenocarcinoma in cytologic preparations
    Jonathan L Hecht
    Department of Pathology, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02215, USA
    Cancer 108:56-9. 2006
    ..The current immunohistochemical study confirmed the effectiveness of MOC-31 as a marker for adenocarcinoma from a broad range of primary sites in body fluid cytology prepared as paraffin sections of cell blocks...
  16. ncbi Placenta microbiology and histology and the risk for severe retinopathy of prematurity
    Minghua L Chen
    Division of Newborn Medicine, Floating Hospital for Children at Tufts Medical Center, Boston, Massachusetts 02111 1526, USA
    Invest Ophthalmol Vis Sci 52:7052-8. 2011
    ..To test the hypothesis that the presence of bacteria and/or histologic inflammation in the placenta of infants born preterm is associated with an increased risk for severe retinopathy of prematurity (ROP)...
  17. ncbi International Internet-based assessment of observer variability for diagnostically challenging endometrial biopsies
    Jonathan D Marotti
    Department of Pathology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts 02215, USA
    Arch Pathol Lab Med 135:464-70. 2011
    ..However, several benign mimics of EIN continue to cause diagnostic confusion...
  18. ncbi Blood protein profiles of infants born before 28 weeks differ by pregnancy complication
    Thomas F McElrath
    Department of Obstetrics and Gynecology, Brigham and Women s Hospital, Boston, MA, USA
    Am J Obstet Gynecol 204:418.e1-418.e12. 2011
    ..Disorders that lead to preterm delivery influence the fetal inflammatory response...
  19. ncbi Relationship between epidemiologic risk factors and hormone receptor expression in ovarian cancer: results from the Nurses' Health Study
    Jonathan L Hecht
    Department of Pathology, Beth Israel Deaconess Medical Center, Boston, MA, USA
    Cancer Epidemiol Biomarkers Prev 18:1624-30. 2009
    ..Reproductive and hormonal risk factors are associated with subgroups of ovarian cancer defined by histologic subtype or ERalpha and PR status. These finding support specific models of hormone mediated triggers of ovarian cancer...
  20. ncbi Risk factors for epithelial ovarian cancer by histologic subtype
    Margaret A Gates
    Channing Laboratory, 181 Longwood Avenue, Boston, MA 02115, USA
    Am J Epidemiol 171:45-53. 2010
    ..03). Results suggest that associations with several ovarian cancer risk factors vary by subtype, and these differences are consistent with known similarities between each major histologic subtype and its normal tissue counterpart...
  21. ncbi Molecular and pathologic aspects of endometrial carcinogenesis
    Jonathan L Hecht
    Department of Pathology, Beth Israel Deaconess Medical Center, 330 Brookline Ave, Boston, MA 02215, USA
    J Clin Oncol 24:4783-91. 2006
    ..This article reviews the genetic aspects of endometrial carcinogenesis and progression. We will define the precursor lesion of type I endometrioid cancer and the role of genetics and estrogen in its progression...
  22. ncbi Microbiologic and histologic characteristics of the extremely preterm infant's placenta predict white matter damage and later cerebral palsy. the ELGAN study
    Alan Leviton
    Department of Neurology, Children s Hospital Boston, Harvard Medical School, Boston, Massachusetts 02115, USA
    Pediatr Res 67:95-101. 2010
    ..Organism recovery does not seem to be needed for placenta inflammation to predict diparetic CP...
  23. ncbi Microglandular hyperplasia: a model for the de novo emergence and evolution of endocervical reserve cells
    Agnieszka K Witkiewicz
    Division of Women's and Perinatal Pathology, Department of Pathology, Brigham and Women's Hospital, Boston, MA 02115, USA
    Hum Pathol 36:154-61. 2005
    ..Similar patterns are seen in cervical neoplasia, suggesting a link between benign and neoplastic cervical epithelial differentiation...
  24. ncbi Invited commentary: Intrauterine epidemiology
    Thomas F McElrath
    Division of Maternal Fetal Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
    Am J Epidemiol 170:159-61; discussion 162-3. 2009
    ..However, these authors have taken a large step toward introducing an "intrauterine" perspective into perinatal epidemiology and into our understanding of the underlying etiologies of preterm birth...
  25. ncbi Keap1 mutations and Nrf2 pathway activation in epithelial ovarian cancer
    Panagiotis A Konstantinopoulos
    Department of Medicine and Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA
    Cancer Res 71:5081-9. 2011
    ..Our findings identify Keap1 mutations in EOC and they suggest a previously unrecognized role for the Keap1-Nrf2 pathway in mediating chemotherapeutic responses in this disease...
  26. ncbi A comparative analysis of lymphatic vessel density in ovarian serous tumors of low malignant potential (borderline tumors) with and without lymph node involvement
    Oluwole Fadare
    Department of Pathology, Wilford Hall Medical Center, Lackland AFB, San Antonio, Texas 78236, USA
    Int J Gynecol Pathol 27:483-90. 2008
    ..We discuss the possibility that nodal deposits may represent metastatic disease from secondary tumor implants...
  27. ncbi Human epididymis protein 4 (HE4) is a secreted glycoprotein that is overexpressed by serous and endometrioid ovarian carcinomas
    Ronny Drapkin
    Department of Cancer Biology, Dana Farber Cancer Institute, Boston, MA 02115, USA
    Cancer Res 65:2162-9. 2005
    ..Its expression in cortical inclusion cysts suggests that formation of Mullerian epithelium is a prerequisite step in the development of some types of EOCs...
  28. ncbi Assessment of factors that affect the quality of performance and interpretation of sonography of adnexal masses
    Deborah Levine
    Department of Radiology, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
    J Ultrasound Med 27:721-8. 2008
    ..The purpose of this study was to assess factors that affect the quality of performance and interpretation of sonography of adnexal masses...
  29. ncbi Characterization of chorioamnionitis in 2nd-trimester C-section placentas and correlation with microorganism recovery from subamniotic tissues
    Jonathan L Hecht
    Department of Pathology, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
    Pediatr Dev Pathol 11:15-22. 2008
    ..Recovery of microorganisms from placental parenchyma is associated with histologic inflammation. The same microorganisms responsible for inciting high-grade chorionic plate inflammation are also most likely to promote fetal inflammation...
  30. ncbi Caffeine, alcohol, smoking, and the risk of incident epithelial ovarian cancer
    Shelley S Tworoger
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    Cancer 112:1169-77. 2008
    ..Therefore, the associations between these exposures and ovarian cancer risk were prospectively examined among 110,454 women in the Nurses' Health Study (NHS) for the smoking analyses and 80,253 women for the dietary analyses...
  31. ncbi Overexpression of the alphavbeta6 integrin in endometrial cancer
    Jonathan L Hecht
    Biogen Idec, Cambridge, MA, USA
    Appl Immunohistochem Mol Morphol 16:543-7. 2008
    ..Expression is high in metastatic lesions. The level of expression of the primary tumor was not indicative of the presence of nodal metastasis; however, the number of cases with nodal metastases was limited...
  32. ncbi Acardiac twin presenting as fetus amorphous with an attenuated umbilical cord
    L Corey Hanley
    Department of Pathology, Beth Israel Deaconess Medical Center, MA 02215, USA
    Pediatr Dev Pathol 10:487-90. 2007
    ..We discuss the controversy regarding the requirement of an umbilical cord in the definition of acardiac twin and distinguish this case from placental teratoma...
  33. ncbi Congenital cytomegalovirus infection: a cause of renal dysplasia?
    Maren Chan
    Department of Pathology at Harvard Medical School, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
    Pediatr Dev Pathol 10:300-4. 2007
    ..Herein, we describe a case of unilateral renal dysplasia in a 19-week fetus with concurrent CMV infection. We believe the present case to be the first description of a virus apparently inducing renal multicystic dysplasia...
  34. ncbi The diagnosis of endometrial carcinomas with clear cells by gynecologic pathologists: an assessment of interobserver variability and associated morphologic features
    Oluwole Fadare
    Department of Pathology, Microbiology, and Immunology, Vanderbilt University School of Medicine, Nashville, TN, USA
    Am J Surg Pathol 36:1107-18. 2012
    ..Cases that display broad and significant qualitative deviations from the aforementioned profile should prompt the consideration of a diagnosis other than CCC...
  35. ncbi Endometrial intraepithelial neoplasia terminology in practice: 4-year experience at a single institution
    Sarah E Kane
    Department of Pathology, Beth Israel Deaconess Medical Center, Boston, MA, USA
    Int J Gynecol Pathol 31:160-165. 2012
    ..In comparison with a previous reproducibility study among expert pathologists on a comparable population from our department, these results for general pathologists show a higher false positive rate for subsequent cancer...
  36. ncbi Anti-Yo antibody associated with occult fallopian tube carcinoma
    Kevin J Selby
    Department of Pathology, Beth Israel Deaconess Medical Center, 330 Brookline Ave, Boston, MA 02215, USA
    Int J Gynecol Pathol 30:536-8. 2011
    ..Her neurologic symptoms are not expected to substantially improve, illustrating the urgent need for early surgical investigation in cases of paraneoplastic syndrome, even in the absence of imaging evidence of a lesion...
  37. ncbi Expression of candidate tumor markers in ovarian carcinoma and benign ovary: evidence for a link between epithelial phenotype and neoplasia
    Ronny Drapkin
    Department of Pathology, Brigham and Women's Hospital, Boston, MA, USA
    Hum Pathol 35:1014-21. 2004
    ..This immunophenotype is preserved in ovarian carcinomas, suggesting that Müllerian metaplasia signals the acquisition of these markers and that their expression is maintained in ovarian carcinomas that originate from this epithelium...
  38. ncbi Myocardial parvovirus B19 persistence: lack of association with clinicopathologic phenotype in adults with heart failure
    Garrick C Stewart
    Division of Cardiovascular Medicine, Brigham and Women s Hospital, Boston, MA, USA
    Circ Heart Fail 4:71-8. 2011
    ..We sought to determine the prevalence of cardiotropic viruses in endomyocardial biopsy (EMB) samples from adult patients with heart failure (HF) and to define the clinicopathologic profile of patients exhibiting viral positivity...
  39. ncbi Management of asymptomatic ovarian and other adnexal cysts imaged at US Society of Radiologists in Ultrasound consensus conference statement
    Deborah Levine
    Department of Radiology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USA
    Ultrasound Q 26:121-31. 2010
    ....
  40. ncbi Does physiologic breakdown mask significant pathology in endometrial biopsies? A retrospective case-control study
    Mark Galan
    Department of Pathology, Beth Israel Deaconess Medical Center, 330 Brookline Ave, Boston, MA 02215, USA
    Arch Pathol Lab Med 130:1847-9. 2006
    ..Adequacy criteria for endometrial biopsy samples do not exist...
  41. ncbi Breastfeeding and risk of ovarian cancer in two prospective cohorts
    Kim N Danforth
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, 181 Longwood Avenue, 3rd Floor, Boston, MA 02115, USA
    Cancer Causes Control 18:517-23. 2007
    ..To describe the association between breastfeeding and ovarian cancer risk in two prospective cohorts...
  42. ncbi Stathmin 1, a marker of PI3K pathway activation and regulator of microtubule dynamics, is expressed in early pelvic serous carcinomas
    Alison M Karst
    Department of Medical Oncology, Dana Farber Cancer Institute, Harvard Medical School, Boston, MA 02215, USA
    Gynecol Oncol 123:5-12. 2011
    ..This study examines the expression of STMN1 and its negative regulator p27 along the morphologic continuum from normal FTE to invasive carcinoma...
  43. ncbi Histologic, surgical, and imaging correlations of adnexal masses
    Elizabeth Asch
    Harvard Medical School, Boston, Massachusetts, USA
    J Ultrasound Med 27:327-42. 2008
    ..The purpose of this study was to quantify, categorize, and illustrate discrepancies between preoperative radiologic, surgical, and pathologic diagnoses and to assess the potential impact of discrepancies on clinical care...
  44. ncbi T-bet regulates metastasis rate in a murine model of primary prostate cancer
    Stanford L Peng
    Department of Immunology and Infectious Diseases, Harvard School of Public Health, Boston, Massachusetts, USA
    Cancer Res 64:452-5. 2004
    ....
  45. ncbi The value of Wilms tumor susceptibility gene 1 in cytologic preparations as a marker for malignant mesothelioma
    Jonathan L Hecht
    Department of Pathology, Brigham and Women's Hospital, Boston, Massachusetts 02115, USA
    Cancer 96:105-9. 2002
    ..In assessment of effusion specimens with metastatic carcinoma, nuclear reactivity for WT1 is highly suggestive of an ovary primary tumor..
  46. ncbi Do enteric neurons make hypocretin?
    Christian R Baumann
    Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Institutes of Medicine, Boston, USA
    Regul Pept 147:1-3. 2008
    ..These results raise doubts about whether enteric neurons produce hypocretin...
  47. ncbi S100B and APP promote a gliocentric shift and impaired neurogenesis in Down syndrome neural progenitors
    Jie Lu
    Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, United States of America
    PLoS ONE 6:e22126. 2011
    ..Thus, the loss in neuronal numbers seen in DS is not merely due to increased HNPs cell death and neurodegeneration, but also a fundamental gliocentric shift in the progenitor pool that impairs neuronal production...
  48. ncbi Pancreatic fine needle aspiration. A comparison of computed tomographic and endoscopic ultrasonographic guidance
    Xiaohua Qian
    Departments of Pathology, Brigham and Women's Hospital and Beth Israel-Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA
    Acta Cytol 47:723-6. 2003
    ..The specificity and negative predictive value of EUS and CT are similar...
  49. ncbi Prediction of endometrial carcinoma by subjective endometrial intraepithelial neoplasia diagnosis
    Jonathan L Hecht
    Department of Pathology, Beth Israel Hospital, Boston, MA 02115, USA
    Mod Pathol 18:324-30. 2005
    ....
  50. ncbi A mesothelial cyst of the round ligament presenting as an inguinal hernia after gonadotropin stimulation for in vitro fertilization
    David A Ryley
    Beth Israel Deaconess Medical Center, Boston, Massachusetts 02215, USA
    Fertil Steril 82:944-6. 2004
    ..To report the case of a round ligament cyst which, as the result of gonadotropin stimulation for IVF, simulated an incarcerated inguinal hernia...
  51. ncbi Intake of folate and related nutrients in relation to risk of epithelial ovarian cancer
    Shelley S Tworoger
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    Am J Epidemiol 163:1101-11. 2006
    ..There was little evidence that folate, methionine, and vitamin B(6) are important in ovarian cancer risk, although dietary folate was inversely associated with risk in some analyses...
  52. ncbi Vulvar acanthosis with altered differentiation: a precursor to verrucous carcinoma?
    Alessandra F Nascimento
    Division of Women s and Perinatal Pathology, Department of Pathology, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    Am J Surg Pathol 28:638-43. 2004
    ..The possibility that vulvar acanthosis with altered differentiation is a precursor to, or a risk factor for, vulvar carcinoma, merits further study...
  53. ncbi Long-term follow-up after polypectomy treatment for adenoma-like dysplastic lesions in ulcerative colitis
    Robert D Odze
    Department of Pathology, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    Clin Gastroenterol Hepatol 2:534-41. 2004
    ..The purpose of this study was to evaluate the long-term outcome of our previously defined group of UC patients, all with adenoma-like DALMs, who were treated by polypectomy...
  54. ncbi Atypical glandular cells of undetermined significance in conventional cervical/vaginal smears and thin-layer preparations
    Jonathan L Hecht
    Department of Pathology, Brigham and Women's Hospital, Boston, Massachusetts 02115, USA
    Cancer 96:1-4. 2002
    ..027% of all cases using TPs and in 0.025% of all cases using CPs. CONCLUSIONS: The use of TPs may increase the diagnostic specificity of AGUS for a high-grade precursor lesion or carcinoma...
  55. ncbi A prospective study of dietary flavonoid intake and incidence of epithelial ovarian cancer
    Margaret A Gates
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA
    Int J Cancer 121:2225-32. 2007
    ..If confirmed, these results would provide an important target for ovarian cancer prevention...