James T Heaton

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. pmc Rat whisker movement after facial nerve lesion: evidence for autonomic contraction of skeletal muscle
    James T Heaton
    Department of Surgery, Massachusetts General Hospital, Harvard Medical School, 55 Fruit Street, Boston, MA 02114, United States Electronic address
    Neuroscience 265:9-20. 2014
  2. doi request reprint Modification and testing of a pneumatic dispensing device for controlled delivery of injectable materials
    James T Heaton
    Center for Laryngeal Surgery and Voice Rehabilitation, Massachusetts General Hospital, Boston, Massachusetts, USA
    Laryngoscope 122:2023-8. 2012
  3. doi request reprint Development of a wireless electromyographically controlled electrolarynx voice prosthesis
    James T Heaton
    Massachusetts General Hospital Department ofSurgery and Harvard Medical School, One Bowdoin Square Floor 11, Boston, MA 02114, USA
    Conf Proc IEEE Eng Med Biol Soc 2011:5352-5. 2011
  4. pmc A system for studying facial nerve function in rats through simultaneous bilateral monitoring of eyelid and whisker movements
    James T Heaton
    Department of Surgery, Harvard Medical School, Massachusetts General Hospital, Boston, MA 02114, United States
    J Neurosci Methods 171:197-206. 2008
  5. pmc Neck surface electromyography as a measure of vocal hyperfunction before and after injection laryngoplasty
    Cara E Stepp
    Center for Laryngeal Surgery and Voice Rehabilitation, Massachusetts General Hospital, USA
    Ann Otol Rhinol Laryngol 119:594-601. 2010
  6. doi request reprint Quantitative analysis of muscle histologic method in rodent facial nerve injury
    Tessa A Hadlock
    Department of Otolaryngology, Massachusetts Eye and Ear Infirmary, 243 Charles St, Boston, MA 02114, USA
    JAMA Facial Plast Surg 15:141-6. 2013
  7. pmc Electromyographic control of a hands-free electrolarynx using neck strap muscles
    Heather L Kubert
    Massachusetts General Hospital Center for Laryngeal Surgery and Voice Rehabilitation, Boston, MA, USA
    J Commun Disord 42:211-25. 2009
  8. doi request reprint Daily facial stimulation to improve recovery after facial nerve repair in rats
    Robin W Lindsay
    Department of Otolaryngology Head and Neck Surgery, Massachusetts Eye and Ear Infirmary, 243 Charles St, Boston, MA 02114, USA
    Arch Facial Plast Surg 12:180-5. 2010
  9. ncbi request reprint Thermal damage during thulium laser dissection of laryngeal soft tissue is reduced with air cooling: ex vivo calf model study
    James A Burns
    Department of Surgery, Harvard Medical School, Boston, Massachusetts, USA
    Ann Otol Rhinol Laryngol 116:853-7. 2007
  10. ncbi request reprint Novel device for tissue cooling during endoscopic laryngeal laser surgery: thermal damage study in an ex vivo calf model
    Hae Jin Koo
    Department of Surgery, Harvard Medical School, and the Center for Laryngeal Surgery and Voice Rehabilitation, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    Ann Otol Rhinol Laryngol 121:485-9. 2012

Collaborators

Detail Information

Publications41

  1. pmc Rat whisker movement after facial nerve lesion: evidence for autonomic contraction of skeletal muscle
    James T Heaton
    Department of Surgery, Massachusetts General Hospital, Harvard Medical School, 55 Fruit Street, Boston, MA 02114, United States Electronic address
    Neuroscience 265:9-20. 2014
    ....
  2. doi request reprint Modification and testing of a pneumatic dispensing device for controlled delivery of injectable materials
    James T Heaton
    Center for Laryngeal Surgery and Voice Rehabilitation, Massachusetts General Hospital, Boston, Massachusetts, USA
    Laryngoscope 122:2023-8. 2012
    ....
  3. doi request reprint Development of a wireless electromyographically controlled electrolarynx voice prosthesis
    James T Heaton
    Massachusetts General Hospital Department ofSurgery and Harvard Medical School, One Bowdoin Square Floor 11, Boston, MA 02114, USA
    Conf Proc IEEE Eng Med Biol Soc 2011:5352-5. 2011
    ..This paper describes both technical and human factors considered while designing the new EMG-EL voice prosthesis...
  4. pmc A system for studying facial nerve function in rats through simultaneous bilateral monitoring of eyelid and whisker movements
    James T Heaton
    Department of Surgery, Harvard Medical School, Massachusetts General Hospital, Boston, MA 02114, United States
    J Neurosci Methods 171:197-206. 2008
    ..The independence observed between whisker and eyelid control indicates that this system may provide a powerful tool for identifying abnormal co-activation of facial zones resulting from aberrant axonal regeneration...
  5. pmc Neck surface electromyography as a measure of vocal hyperfunction before and after injection laryngoplasty
    Cara E Stepp
    Center for Laryngeal Surgery and Voice Rehabilitation, Massachusetts General Hospital, USA
    Ann Otol Rhinol Laryngol 119:594-601. 2010
    ....
  6. doi request reprint Quantitative analysis of muscle histologic method in rodent facial nerve injury
    Tessa A Hadlock
    Department of Otolaryngology, Massachusetts Eye and Ear Infirmary, 243 Charles St, Boston, MA 02114, USA
    JAMA Facial Plast Surg 15:141-6. 2013
    ..To describe denervation features of facial musculature following facial nerve injury in a rodent model...
  7. pmc Electromyographic control of a hands-free electrolarynx using neck strap muscles
    Heather L Kubert
    Massachusetts General Hospital Center for Laryngeal Surgery and Voice Rehabilitation, Boston, MA, USA
    J Commun Disord 42:211-25. 2009
    ..Neck strap muscles have activation patterns capable of simple alaryngeal voice control without requiring RLN transfer...
  8. doi request reprint Daily facial stimulation to improve recovery after facial nerve repair in rats
    Robin W Lindsay
    Department of Otolaryngology Head and Neck Surgery, Massachusetts Eye and Ear Infirmary, 243 Charles St, Boston, MA 02114, USA
    Arch Facial Plast Surg 12:180-5. 2010
    ..To establish whether daily mechanical stimulation improves functional recovery of whisking after facial nerve transection injury and repair in rats...
  9. ncbi request reprint Thermal damage during thulium laser dissection of laryngeal soft tissue is reduced with air cooling: ex vivo calf model study
    James A Burns
    Department of Surgery, Harvard Medical School, Boston, Massachusetts, USA
    Ann Otol Rhinol Laryngol 116:853-7. 2007
    ..This study investigated temperature changes and thermal trauma during thulium laser dissection of laryngeal tissue, with and without air cooling, in an ex vivo model...
  10. ncbi request reprint Novel device for tissue cooling during endoscopic laryngeal laser surgery: thermal damage study in an ex vivo calf model
    Hae Jin Koo
    Department of Surgery, Harvard Medical School, and the Center for Laryngeal Surgery and Voice Rehabilitation, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    Ann Otol Rhinol Laryngol 121:485-9. 2012
    ....
  11. ncbi request reprint Assessment of canine vocal fold function after injection of a new biomaterial designed to treat phonatory mucosal scarring
    Sandeep S Karajanagi
    Department of Surgery, Center for Laryngeal Surgery and Voice Rehabilitation, Massachusetts General Hospital, Boston, MA 02114, USA
    Ann Otol Rhinol Laryngol 120:175-84. 2011
    ..By using a US Food and Drug Administration-approved polymer, polyethylene glycol (PEG), we created a novel hydrogel (PEG30) and investigated its effects on multiple vocal fold structural and functional parameters...
  12. pmc Characteristics of phonatory function in singers and nonsingers with vocal fold nodules
    Cara E Stepp
    Harvard MIT Division of Health Science and Technology, Cambridge, Massachusetts, USA
    J Voice 25:714-24. 2011
    ..The goals of this study were to determine if there were significant differences between singers and nonsingers in the morphology of vocal nodules and the associated impact on vocal function...
  13. ncbi request reprint The effect of electrical and mechanical stimulation on the regenerating rodent facial nerve
    Tessa Hadlock
    Department of Otolaryngology, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts, USA
    Laryngoscope 120:1094-102. 2010
    ..Herein, we investigated the degree to which manual target muscle manipulation and brief electrical stimulation of the facial nerve, alone or in combination, affects recovery following rat facial nerve injury...
  14. doi request reprint Rodent facial nerve recovery after selected lesions and repair techniques
    Tessa A Hadlock
    Department of Otology and Laryngology, Massachusetts Eye and Ear Infirmary, Boston, Mass 02114, USA
    Plast Reconstr Surg 125:99-109. 2010
    ..The authors quantitatively compared recovery of vibrissal and ocular function following three types of clinically relevant nerve injury...
  15. doi request reprint Functional assessments of the rodent facial nerve: a synkinesis model
    Tessa Hadlock
    Department of Otology and Laryngology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts 02114, USA
    Laryngoscope 118:1744-9. 2008
    ..Our objective was to establish normative parameters for both spontaneous and induced whisking and blinking behavior in a large group of normal rats...
  16. pmc Facial nerve repair: fibrin adhesive coaptation versus epineurial suture repair in a rodent model
    Christopher J Knox
    Department of Otolaryngology, Massachusetts Eye and Ear Infirmary and Harvard Medical School, Boston, Massachusetts 02114, USA
    Laryngoscope 123:1618-21. 2013
    ..We compared functional recovery following suture neurorrhaphy to FAC in a rodent facial nerve model...
  17. doi request reprint Three-dimensional hydrogel model using adipose-derived stem cells for vocal fold augmentation
    Hyoungshin Park
    Department of Surgery, Center for Laryngeal Surgery and Voice Rehabilitation, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    Tissue Eng Part A 16:535-43. 2010
    ..In particular, cogels of HA or collagen with fibrin enhanced proliferation, differentiation, and elastin expression...
  18. pmc Evidence for facial nerve-independent mechanisms of blinking in the rat
    James T Heaton
    Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA
    Invest Ophthalmol Vis Sci 51:179-82. 2010
    ..This study was undertaken to determine the maintenance of rat corneal health and eye closure capability after lesion of the OO, RB, or both...
  19. doi request reprint The effects of potential neuroprotective agents on rat facial function recovery following facial nerve injury
    Kalpesh T Vakharia
    Department of Otology and Laryngology, Massachusetts Eye and Ear Infirmary and Harvard Medical School, Boston, MA 02114, USA
    Otolaryngol Head Neck Surg 144:53-9. 2011
    ..To evaluate whether a series of pharmacologic agents with potential neuroprotective effects accelerate and/or improve facial function recovery after facial nerve crush injury...
  20. ncbi request reprint A new instrument for intraoperative assessment of individual vocal folds
    James T Heaton
    Department of Surgery, Harvard Medical School, Massachusetts General Hospital Boston, Massachusetts 02114, USA
    Laryngoscope 115:1223-9. 2005
    ..We therefore developed and bench-tested a new device we refer to as the aerodynamic vocal fold driver (AVFD)...
  21. ncbi request reprint Cooling the "oven": a temperature study of air and glottal tissue during laser surgery in an ex vivo calf larynx model
    James A Burns
    Department of Surgery, Harvard Medical School, Boston, MA, USA
    Ann Otol Rhinol Laryngol 119:684-9. 2010
    ..We report the effects of cooling on air and tissue temperatures that occurred during simulated laryngeal laser surgery with KTP and thulium lasers in an ex vivo calf model...
  22. doi request reprint Predicting clinical efficacy of photoangiolytic and cutting/ablating lasers using the chick chorioallantoic membrane model: implications for endoscopic voice surgery
    James A Burns
    Department of Surgery, Harvard Medical School, Center for Laryngeal Surgery and Voice Rehabilitation, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    Laryngoscope 118:1109-24. 2008
    ..Such information is essential for optimizing the effectiveness of lasers in treating laryngeal pathology while preserving vocal function...
  23. pmc Comparison of neck tension palpation rating systems with surface electromyographic and acoustic measures in vocal hyperfunction
    Cara E Stepp
    Division of Health Sciences and Technology, Harvard MIT Cambridge, Massachusetts, USA
    J Voice 25:67-75. 2011
    ..Palpation rating scales do not reliably capture changes that may occur in neck muscle tension of typical voice therapy patients over one session. Consequently, little can be concluded from correlations between sEMG and palpation ratings...
  24. ncbi request reprint Carbon dioxide laser fiber for laryngeal cancer surgery
    Steven M Zeitels
    Department of Surgery, Harvard Medical School, Center for Laryngeal Surgery and Voice Rehabilitation, Massachusetts General Hospital, One Bowdoin Square, 11th Floor, Boston, MA 02114, USA
    Ann Otol Rhinol Laryngol 115:535-41. 2006
    ..However, dissection is limited to mirror-reflected line-of-sight delivery of the laser. A recently developed flexible, hollow photonic bandgap fiber (PBF) appears to offer advantages in endolaryngeal dissection...
  25. ncbi request reprint Functional recovery after facial nerve cable grafting in a rodent model
    Marc H Hohman
    Department of Otology and Laryngology, Harvard Medical School, Boston, Massachusetts2Division of Facial Plastic Surgery, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts
    JAMA Facial Plast Surg 16:20-4. 2014
    ..Cable grafting is widely considered to be the preferred alternative to primary repair of the injured facial nerve; however, quantitative comparison of the 2 techniques has not been previously undertaken in a rodent model...
  26. ncbi request reprint Ambulatory monitoring of disordered voices
    Robert E Hillman
    Department of Surgery, Harvard Medical School, MGH Center for Laryngeal Surgery and Voice Rehabilitation, One Bowdoin Square, Ilth Floor, Boston, MA 02114, USA
    Ann Otol Rhinol Laryngol 115:795-801. 2006
    ....
  27. ncbi request reprint Effects of 532 nm pulsed-KTP laser parameters on vessel ablation in the avian chorioallantoic membrane: implications for vocal fold mucosa
    Matthew S Broadhurst
    Department of Surgery, Harvard Medical School, Center for Laryngeal Surgery and Voice Rehabilitation, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    Laryngoscope 117:220-5. 2007
    ....
  28. pmc Post-laryngectomy speech respiration patterns
    Cara E Stepp
    Center for Laryngeal Surgery and Voice Rehabilitation, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    Ann Otol Rhinol Laryngol 117:557-63. 2008
    ..The goal of this study was to determine whether speech breathing changes over time in laryngectomy patients who use an electrolarynx, to explore the potential of using respiratory signals to control an artificial voice source...
  29. ncbi request reprint Use of muscle fibrillation for tracking nerve regeneration
    James T Heaton
    Department of Surgery, Massachusetts General Hospital, One Bowdoin Square, 11th Floor, Boston, MA 02114, USA
    Muscle Nerve 31:235-41. 2005
    ....
  30. pmc A novel method of head fixation for the study of rodent facial function
    Tessa Hadlock
    Department of Otolaryngology, Division of Facial Plastic and Reconstructive Surgery, Massachusetts Eye and Ear Infirmary and Harvard Medical School, 243 Charles St, Boston, MA 02114, USA
    Exp Neurol 205:279-82. 2007
    ..Here we describe a head fixation device that is inexpensive, easy to build, less prone to infection, preserves access to the cranial midline, and permits repeated measurements over many months...
  31. doi request reprint Early versus late injection medialization for unilateral vocal cord paralysis
    Aaron D Friedman
    Department of Surgery, Harvard Medical School, Center for Laryngeal Surgery and Voice Rehabilitation, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    Laryngoscope 120:2042-6. 2010
    ..late (>6 months) injection medialization laryngoplasty impacts the need for subsequent open-neck reconstruction to restore vocal function in patients with unilateral vocal cord paralysis...
  32. ncbi request reprint Initial anatomic geographic presentation of glottal dysplasia
    Yonatan Lahav
    Department of Surgery, Harvard Medical School, Center for Laryngeal Surgery and Voice Rehabilitation, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    Ann Otol Rhinol Laryngol 118:321-5. 2009
    ....
  33. ncbi request reprint Design and implementation of a hands-free electrolarynx device controlled by neck strap muscle electromyographic activity
    Ehab A Goldstein
    Harvard MIT Division of Health Science and Technology, and the Division of Engineering and Applied Sciences, Harvard University, Cambridge, MA 02143, USA
    IEEE Trans Biomed Eng 51:325-32. 2004
    ..The EMG-EL voice reaction time appears to be adequate for use in a day-to-day conversation...
  34. ncbi request reprint Determining the threshold for asymmetry detection in facial expressions
    Marc H Hohman
    Department of Otology and Laryngology, Harvard Medical School, Boston, Massachusetts, U S A Facial Nerve Center, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts, U S A
    Laryngoscope 124:860-5. 2014
    ..To quantify the threshold for human perception of asymmetry for eyebrow elevation, eye closure, and smile, and to ascertain whether asymmetry detection thresholds and perceived severity of asymmetry differ in distinct facial zones...
  35. doi request reprint Nimodipine and acceleration of functional recovery of the facial nerve after crush injury
    Robin W Lindsay
    Department of Otolaryngology Head and Neck Surgery, Massachusetts Eye and Ear Infirmary and Harvard Medical School, Boston, USA
    Arch Facial Plast Surg 12:49-52. 2010
    ..To establish whether nimodipine, a calcium channel blocker, accelerates or otherwise improves functional recovery of whisking after facial nerve crush injury in the rat...
  36. doi request reprint Comparison of effects of 2 harvesting methods on fat autograft
    Hyoungshin Park
    Center for Laryngeal Surgery and Voice Rehabilitation, Department of Surgery, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    Laryngoscope 118:1493-9. 2008
    ..Considering this, we compared viability of fat tissues obtained by these two techniques. We also examined whether basic fibroblast growth factor (bFGF) would increase cell proliferation in samples harvested by these methods...
  37. ncbi request reprint Infrared-based blink-detecting glasses for facial pacing: toward a bionic blink
    Alice Frigerio
    Human Physiology Section, Department of Pathophysiology and Transplantation, Universita degli Studi di Milano, Milan, Italy Facial Nerve Center, Carolyn and Peter Lynch Center for Laser and Reconstructive Surgery, Division of Facial Plastic and Reconstructive Surgery, Department of Otology and Laryngology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston
    JAMA Facial Plast Surg 16:211-8. 2014
    ..Future versions will aim to mitigate detection errors by using multiple IR emitter-detector units mounted on glasses, and alternative frame designs may reduce shifting of the sensors relative to the eye during facial movements...
  38. ncbi request reprint Surface electromyographic activity in total laryngectomy patients following laryngeal nerve transfer to neck strap muscles
    James T Heaton
    W M Keck Foundation Neural Prosthesis Research Center, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts, USA
    Ann Otol Rhinol Laryngol 113:754-64. 2004
    ..The results show that neck surface electromyography is an effective control source for hands-free electrolarynx activation, and that RLN transfer may provide the best approach for obtaining phonation-related activity...
  39. ncbi request reprint Hind limb ischemia-reperfusion injury in diet-induced obese mice
    Hassan Albadawi
    Department of Surgery, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts Division of Vascular and Endovascular Surgery, Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts Electronic address
    J Surg Res 190:683-91. 2014
    ..This study compared the histologic, metabolic, and functional outcomes after hind limb IR in diet-induced obese (DIO) and non-diabetic (ND) mice during the acute and the regenerative phases of IR...
  40. doi request reprint Imaging of the calf vocal fold with high-frequency ultrasound
    Conor J Walsh
    Department of Mechanical Engineering, Harvard MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, MA, USA
    Laryngoscope 118:1894-9. 2008
    ..The objective of this study was to assess the ability of high-frequency ultrasound to image vocal fold anatomy and injected biomaterials...
  41. ncbi request reprint Training effects on speech production using a hands-free electromyographically controlled electrolarynx
    Ehab A Goldstein
    Harvard University, Cambridge, MA, USA
    J Speech Lang Hear Res 50:335-51. 2007
    ..An electromyographically controlled EL (EMG-EL) was designed and implemented to provide hands-free control with dynamic pitch modulation...