D G Harper

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. pmc Tissue-specific differences in brain phosphodiesters in late-life major depression
    David G Harper
    Geriatric Psychiatry Program, McLean Hospital, Belmont, MA Department of Psychiatry, Harvard Medical School, Boston, MA Electronic address
    Am J Geriatr Psychiatry 22:499-509. 2014
  2. pmc Energetic and cell membrane metabolic products in patients with primary insomnia: a 31-phosphorus magnetic resonance spectroscopy study at 4 tesla
    David G Harper
    Geriatric Psychiatry Program, Harvard Medical School, Boston, MA, USA
    Sleep 36:493-500. 2013
  3. pmc Dorsomedial SCN neuronal subpopulations subserve different functions in human dementia
    David G Harper
    Geriatric Psychiatry Program, McLean Hospital, 115 Mill Street, Belmont, MA 02478, USA
    Brain 131:1609-17. 2008
  4. ncbi request reprint Disturbance of endogenous circadian rhythm in aging and Alzheimer disease
    David G Harper
    Department of Psychiatry, McLean Hospital, 115 Mill Street, Belmont, MA 02478, USA
    Am J Geriatr Psychiatry 13:359-68. 2005
  5. ncbi request reprint Dementia severity and Lewy bodies affect circadian rhythms in Alzheimer disease
    David G Harper
    Geriatric Psychiatric Program, Department of Psychiatry, McLean Hospital, Harvard Medical School, Belmont, MA, USA
    Neurobiol Aging 25:771-81. 2004
  6. ncbi request reprint Differential circadian rhythm disturbances in men with Alzheimer disease and frontotemporal degeneration
    D G Harper
    Admissions Building, McLean Hospital, 115 Mill St, Belmont, MA 02478, USA
    Arch Gen Psychiatry 58:353-60. 2001
  7. doi request reprint Severe impairment of circadian rhythm in Alzheimer's disease
    L Volicer
    E N Rogers Memorial Veterans Hospital, Bedford, MA, USA
    J Nutr Health Aging 16:888-90. 2012
  8. ncbi request reprint Sundowning and circadian rhythms in Alzheimer's disease
    L Volicer
    Geriatric Research Education Clinical Center, Edith Nourse Rogers Memorial Veterans Hospital, MA, USA
    Am J Psychiatry 158:704-11. 2001
  9. doi request reprint 31Phosphorus magnetic resonance spectroscopy study of tissue specific changes in high energy phosphates before and after sertraline treatment of geriatric depression
    Brent P Forester
    Geriatric Psychiatry Research Program, McLean Hospital, Belmont, MA, USA
    Int J Geriatr Psychiatry 24:788-97. 2009
  10. doi request reprint Age-related changes in brain energetics and phospholipid metabolism
    Brent P Forester
    Geriatric Psychiatry Research Program, McLean Hospital, Belmont, MA, USA
    NMR Biomed 23:242-50. 2010

Research Grants

Detail Information

Publications13

  1. pmc Tissue-specific differences in brain phosphodiesters in late-life major depression
    David G Harper
    Geriatric Psychiatry Program, McLean Hospital, Belmont, MA Department of Psychiatry, Harvard Medical School, Boston, MA Electronic address
    Am J Geriatr Psychiatry 22:499-509. 2014
    ....
  2. pmc Energetic and cell membrane metabolic products in patients with primary insomnia: a 31-phosphorus magnetic resonance spectroscopy study at 4 tesla
    David G Harper
    Geriatric Psychiatry Program, Harvard Medical School, Boston, MA, USA
    Sleep 36:493-500. 2013
    ....
  3. pmc Dorsomedial SCN neuronal subpopulations subserve different functions in human dementia
    David G Harper
    Geriatric Psychiatry Program, McLean Hospital, 115 Mill Street, Belmont, MA 02478, USA
    Brain 131:1609-17. 2008
    ....
  4. ncbi request reprint Disturbance of endogenous circadian rhythm in aging and Alzheimer disease
    David G Harper
    Department of Psychiatry, McLean Hospital, 115 Mill Street, Belmont, MA 02478, USA
    Am J Geriatr Psychiatry 13:359-68. 2005
    ..The authors evaluated the similarities and differences between the consequences of aging and AD on endogenous circadian rhythm...
  5. ncbi request reprint Dementia severity and Lewy bodies affect circadian rhythms in Alzheimer disease
    David G Harper
    Geriatric Psychiatric Program, Department of Psychiatry, McLean Hospital, Harvard Medical School, Belmont, MA, USA
    Neurobiol Aging 25:771-81. 2004
    ....
  6. ncbi request reprint Differential circadian rhythm disturbances in men with Alzheimer disease and frontotemporal degeneration
    D G Harper
    Admissions Building, McLean Hospital, 115 Mill St, Belmont, MA 02478, USA
    Arch Gen Psychiatry 58:353-60. 2001
    ..Recent studies have implicated dysfunction of the circadian pacemaker in the etiology of these disturbances in dementia...
  7. doi request reprint Severe impairment of circadian rhythm in Alzheimer's disease
    L Volicer
    E N Rogers Memorial Veterans Hospital, Bedford, MA, USA
    J Nutr Health Aging 16:888-90. 2012
    ..These changes probably reflect gradual lengthening of the circadian cycle that at one point became extremely lengthened before returning to the 24 hr cycle...
  8. ncbi request reprint Sundowning and circadian rhythms in Alzheimer's disease
    L Volicer
    Geriatric Research Education Clinical Center, Edith Nourse Rogers Memorial Veterans Hospital, MA, USA
    Am J Psychiatry 158:704-11. 2001
    ..CONCLUSIONS: These data indicate that Alzheimer's disease causes disturbances of circadian rhythms and that sundowning is related to a phase delay of body temperature caused by Alzheimer's disease...
  9. doi request reprint 31Phosphorus magnetic resonance spectroscopy study of tissue specific changes in high energy phosphates before and after sertraline treatment of geriatric depression
    Brent P Forester
    Geriatric Psychiatry Research Program, McLean Hospital, Belmont, MA, USA
    Int J Geriatr Psychiatry 24:788-97. 2009
    ....
  10. doi request reprint Age-related changes in brain energetics and phospholipid metabolism
    Brent P Forester
    Geriatric Psychiatry Research Program, McLean Hospital, Belmont, MA, USA
    NMR Biomed 23:242-50. 2010
    ..Unlike some previous studies of aging and brain chemistry, this study examined healthy, non-demented and psychiatrically stable older adults and specifically analyzed gray-white matter differences in brain metabolism...
  11. doi request reprint Activation of suprachiasmatic nuclei and primary visual cortex depends upon time of day
    Ram L P Vimal
    Brain Imaging Center, McLean Hospital, Belmont, MA, USA
    Eur J Neurosci 29:399-410. 2009
    ..3 (2003) 945] for the SCN activity at critical intensity threshold; and (ii) the interaction of the melanopsin-based signals with the rod-cone signals at the 'giant' retinal ganglion cells [Nature, 433 (2005) 749] for the V1 activity...
  12. ncbi request reprint Beyond the "C" in MCI: noncognitive symptoms in amnestic and non-amnestic mild cognitive impairment
    James M Ellison
    Geriatric Psychiatry Program, McLean Hospital, Belmont, MA 02478, USA
    CNS Spectr 13:66-72. 2008
    ....
  13. ncbi request reprint Increase in core body temperature of Alzheimer's disease patients as a possible indicator of chronic neuroinflammation: a meta-analysis
    Andis Klegeris
    Kinsmen Laboratory of Neurological Research, University of British Columbia, Vancouver, BC, Canada
    Gerontology 53:7-11. 2007
    ..Such increases have been observed in AD brains. We hypothesized that these increased levels of inflammatory mediators could lead to an increase in core body temperature in AD patients...

Research Grants5

  1. Sleep, Circadian Rhythms and Dementing Illnesses
    David Harper; Fiscal Year: 2003
    ..abstract_text> ..
  2. Sleep, Circadian Rhythms and Dementing Illnesses
    David Harper; Fiscal Year: 2004
    ..abstract_text> ..
  3. Sleep, Circadian Rhythms and Dementing Illnesses
    David Harper; Fiscal Year: 2005
    ..abstract_text> ..
  4. Sleep, Circadian Rhythms and Dementing Illnesses
    David Harper; Fiscal Year: 2006
    ..abstract_text> ..
  5. Sleep, Circadian Rhythms and Dementing Illnesses
    David Harper; Fiscal Year: 2007
    ..abstract_text> ..