Genomes and Genes
Affiliation: Harvard University
- The clinical features of the overlap between COPD and asthmaMegan Hardin
Channing Laboratory, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
Respir Res 12:127. 2011..The coexistence of COPD and asthma is widely recognized but has not been well described. This study characterizes clinical features, spirometry, and chest CT scans of smoking subjects with both COPD and asthma...
- CHRNA3/5, IREB2, and ADCY2 are associated with severe chronic obstructive pulmonary disease in PolandMegan Hardin
Channing Laboratory, Brigham and Women s Hospital, Boston, MA 02115, USA
Am J Respir Cell Mol Biol 47:203-8. 2012....
- Identification of a chronic obstructive pulmonary disease genetic determinant that regulates HHIPXiaobo Zhou
Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
Hum Mol Genet 21:1325-35. 2012..Together, our findings reveal one mechanism through which SNPs upstream of the HHIP gene modulate the expression of HHIP and functionally implicate reduced HHIP gene expression in the pathogenesis of COPD...