D W Hanto

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. ncbi request reprint A 50-year-old man with hepatitis C and cirrhosis needing liver transplantation
    Douglas W Hanto
    Division of Transplantation, Department of Surgery, Beth Israel Deaconess Medical Center, Boston, Mass, USA
    JAMA 290:3238-46. 2003
  2. ncbi request reprint Liver and intestine transplantation: summary analysis, 1994-2003
    Douglas W Hanto
    Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USA
    Am J Transplant 5:916-33. 2005
  3. ncbi request reprint Ethical challenges posed by the solicitation of deceased and living organ donors
    Douglas W Hanto
    Division of Transplantation, Department of Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, USA
    N Engl J Med 356:1062-6. 2007
  4. ncbi request reprint Reliability of voluntary and compulsory databases and registries in the United States
    Douglas W Hanto
    Department of Surgery, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA 02215, USA
    Transplantation 75:2162-4. 2003
  5. doi request reprint Intraoperative administration of inhaled carbon monoxide reduces delayed graft function in kidney allografts in Swine
    D W Hanto
    Harvard Medical School, the Transplant Institute and the Department of Surgery, Division of Transplantation at Beth Israel Deaconess Medical Center, Boston, MA, USA
    Am J Transplant 10:2421-30. 2010
  6. ncbi request reprint The medical evaluation of living kidney donors: a survey of US transplant centers
    D A Mandelbrot
    Department of Medicine, The Transplant Center, Beth Israel Deaconess Medical Center, Boston, MA, USA
    Am J Transplant 7:2333-43. 2007
  7. pmc Rational rationing or discrimination: balancing equity and efficiency considerations in kidney allocation
    K Ladin
    The Transplant Institute and Center for Transplant Outcomes and Quality Improvement at Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USA
    Am J Transplant 11:2317-21. 2011
  8. ncbi request reprint Evaluating living kidney donors: relationship types, psychosocial criteria, and consent processes at US transplant programs
    J R Rodrigue
    Department of Psychiatry, The Transplant Center, Beth Israel Deaconess Medical Center, Boston, MA, USA
    Am J Transplant 7:2326-32. 2007
  9. ncbi request reprint Primary nonfunction (PNF) in the MELD Era: An SRTR database analysis
    S R Johnson
    The Transplant Center, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts, USA
    Am J Transplant 7:1003-9. 2007
  10. ncbi request reprint Use of low-dose OKT3 as induction therapy in liver transplantation
    J F Whiting
    Department of Surgery, University of Cincinnati Medical Center, Ohio 45267 0558, USA
    Transplantation 65:577-80. 1998

Detail Information

Publications41

  1. ncbi request reprint A 50-year-old man with hepatitis C and cirrhosis needing liver transplantation
    Douglas W Hanto
    Division of Transplantation, Department of Surgery, Beth Israel Deaconess Medical Center, Boston, Mass, USA
    JAMA 290:3238-46. 2003
  2. ncbi request reprint Liver and intestine transplantation: summary analysis, 1994-2003
    Douglas W Hanto
    Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USA
    Am J Transplant 5:916-33. 2005
    ..Intestine transplantation is performed with slowly increasing frequency and success. Early graft losses and rejection rates have changed little since 1994, but rejection is easier to control and long-term survival is improving...
  3. ncbi request reprint Ethical challenges posed by the solicitation of deceased and living organ donors
    Douglas W Hanto
    Division of Transplantation, Department of Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, USA
    N Engl J Med 356:1062-6. 2007
  4. ncbi request reprint Reliability of voluntary and compulsory databases and registries in the United States
    Douglas W Hanto
    Department of Surgery, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA 02215, USA
    Transplantation 75:2162-4. 2003
    ..Audits can and should be performed to guarantee the reliability of the data and accuracy of the conclusions drawn from this data as was done by the European Liver Transplant Registry...
  5. doi request reprint Intraoperative administration of inhaled carbon monoxide reduces delayed graft function in kidney allografts in Swine
    D W Hanto
    Harvard Medical School, the Transplant Institute and the Department of Surgery, Division of Transplantation at Beth Israel Deaconess Medical Center, Boston, MA, USA
    Am J Transplant 10:2421-30. 2010
    ..The efficacy of CO on improving graft function posttransplant validates the model and offers a potentially important therapeutic strategy to improve transplant outcomes...
  6. ncbi request reprint The medical evaluation of living kidney donors: a survey of US transplant centers
    D A Mandelbrot
    Department of Medicine, The Transplant Center, Beth Israel Deaconess Medical Center, Boston, MA, USA
    Am J Transplant 7:2333-43. 2007
    ..These findings highlight the need for more data on long-term outcomes in various types of donors with potential morbidities related to donation...
  7. pmc Rational rationing or discrimination: balancing equity and efficiency considerations in kidney allocation
    K Ladin
    The Transplant Institute and Center for Transplant Outcomes and Quality Improvement at Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USA
    Am J Transplant 11:2317-21. 2011
    ..We argue that, despite weaknesses of the proposal and the importance of maintaining consistency in patient and provider expectations over time, the proposal represents a needed first step in balancing equity and efficiency...
  8. ncbi request reprint Evaluating living kidney donors: relationship types, psychosocial criteria, and consent processes at US transplant programs
    J R Rodrigue
    Department of Psychiatry, The Transplant Center, Beth Israel Deaconess Medical Center, Boston, MA, USA
    Am J Transplant 7:2326-32. 2007
    ..Whether greater consensus should be reached on these donor evaluation practices, especially in the context of more expansive use of living donor kidney transplantation, is discussed...
  9. ncbi request reprint Primary nonfunction (PNF) in the MELD Era: An SRTR database analysis
    S R Johnson
    The Transplant Center, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts, USA
    Am J Transplant 7:1003-9. 2007
    ..In this analysis of PNF in the MELD era the incidence of PNF does not appear to have increased from prior reports. Risk factors for PNF are related to donor age and severity of recipient illness...
  10. ncbi request reprint Use of low-dose OKT3 as induction therapy in liver transplantation
    J F Whiting
    Department of Surgery, University of Cincinnati Medical Center, Ohio 45267 0558, USA
    Transplantation 65:577-80. 1998
    ..A pilot study was performed to prospectively evaluate the safety and efficacy of "low-dose" OKT3 induction after liver transplantation...
  11. doi request reprint Understanding disparities in transplantation: do social networks provide the missing clue?
    K Ladin
    Transplant Institute and Center for Transplant Outcomes and Quality Improvement at Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA
    Am J Transplant 10:472-6. 2010
    ..This paper presents a novel application of social network analysis to transplantation, illustrating implications for disparities and future clinical interventions...
  12. pmc Framing disparities along the continuum of care from chronic kidney disease to transplantation: barriers and interventions
    K Ladin
    Transplant Institute and Center for Transplant Outcomes and Quality Improvement at Beth Israel Deaconess Medical and Harvard Medical School, Boston, MA, USA
    Am J Transplant 9:669-74. 2009
    ....
  13. ncbi request reprint Severe hypoglycaemia post-gastric bypass requiring partial pancreatectomy: evidence for inappropriate insulin secretion and pancreatic islet hyperplasia
    M E Patti
    Research Division, Joslin Diabetes Center, Boston, MA 02215, USA
    Diabetologia 48:2236-40. 2005
    ..We investigated three patients with severe postprandial hypoglycaemia and hyperinsulinaemia unresponsive to diet, octreotide and diazoxide with the aim of elucidating the pathological mechanisms involved...
  14. doi request reprint Web-based requests for living organ donors: who are the solicitors?
    James R Rodrigue
    Department of Psychiatry, The Transplant Center, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
    Clin Transplant 22:749-53. 2008
    ..Specifically, in some instances, a Good Samaritan's pursuit of living kidney donation may be based less on information potentially relevant to transplant outcome and more on the persuasiveness of the appeal...
  15. doi request reprint Donor postextubation hypotension and age correlate with outcome after donation after cardiac death transplantation
    Karen J Ho
    Department of Surgery, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
    Transplantation 85:1588-94. 2008
    ..We hypothesized that donor postextubation parameters, including duration and severity of hemodynamic instability or hypoxia might be a better predictor of subsequent graft function...
  16. ncbi request reprint ABO-incompatible liver transplantation with no immunological graft losses using total plasma exchange, splenectomy, and quadruple immunosuppression: evidence for accommodation
    Douglas W Hanto
    Department of Surgery, Division of Transplantation, University of Cincinnati College of Medicine, Cincinnati, OH, USA
    Liver Transpl 9:22-30. 2003
    ..Recovery of isohemagglutinin antibody levels without humoral rejection suggests that accommodation may be the protective mechanism preventing late antibody-mediated rejection...
  17. doi request reprint Timing of sirolimus conversion influences recovery of renal function in liver transplant recipients
    Christin C Rogers
    Department of Pharmacy, Beth Israel Deaconess Medical Center, Boston, MA, USA
    Clin Transplant 23:887-96. 2009
    ..The only improvement in the LC group was from conversion to the three-month time point. We conclude that EC to SRL results in a profound improvement in eGFR that begins at three months and is sustained beyond one yr...
  18. ncbi request reprint Intensive care unit extubation does not preclude extrarenal organ recovery from donors after cardiac death
    Scott R Johnson
    Division of Transplant Surgery, Department of Surgery, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA 02215, USA
    Transplantation 80:1244-50. 2005
    ..We have sought to increase the utilization of both renal and extrarenal organs from donors after cardiac death (DCD), including DCD donors with ICU extubation...
  19. ncbi request reprint Four cases of cardiopulmonary thromboembolism during liver transplantation without the use of antifibrinolytic drugs
    Adam B Lerner
    BIDMC Department of Anesthesia, West Campus, CC 540, 1 Deaconess Rd, Boston, MA 02215, USA
    Anesth Analg 101:1608-12. 2005
    ..Possible causes of thromboembolism, clinical management, use of thromboelastography, and the role of antifibrinolytic drugs are discussed...
  20. ncbi request reprint Fatigue and sleep quality before and after liver transplantation
    James R Rodrigue
    Transplant Institute, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02215, USA
    Prog Transplant 20:221-33. 2010
    ..Recent publications suggest that fatigue and sleep disturbance are problems in patients with chronic liver disease and in liver transplant recipients...
  21. ncbi request reprint Older living donors provide excellent quality kidneys: a single center experience (older living donors)
    Scott R Johnson
    Division of Transplant Surgery, Department of Surgery, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
    Clin Transplant 19:600-6. 2005
    ..The role of advanced age live donors remains controversial because of decline in glomerular filtration rate and perceived increased risks of perioperative complications...
  22. doi request reprint A cross-sectional study of fatigue and sleep quality before and after kidney transplantation
    James R Rodrigue
    The Transplant Institute, Beth Israel Deaconess Center for Transplant Outcomes and Quality Improvement and Medical Center, Harvard Medical School, Boston, MA 02215, USA
    Clin Transplant 25:E13-21. 2011
    ..Fatigue and sleep disturbances are common before and after KTx, and study findings have important implications for their assessment and management...
  23. doi request reprint Patients' willingness to accept expanded criteria donor liver transplantation
    J R Rodrigue
    Center for Transplant Outcomes and Quality Improvement, The Transplant Institute, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA
    Am J Transplant 11:1705-11. 2011
    ..Findings highlight the importance of assessing patients' willingness to pursue ECD LTx and the relative mortality risks they are willing to accept...
  24. doi request reprint Outcomes with conversion from calcineurin inhibitors to sirolimus after renal transplantation in the context of steroid withdrawal or steroid continuation
    Ogo I Egbuna
    The Transplant Institute, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
    Transplantation 88:684-92. 2009
    ..A number of studies have suggested that conversion from calcineurin inhibitors (CNI) to sirolimus (SRL) can improve graft function in renal transplant patients. None of these studies has converted patients to SRL in the absence of steroids...
  25. ncbi request reprint Retransplantation after post-transplant lymphoproliferative disorders: an OPTN/UNOS database analysis
    S R Johnson
    The Transplant Center, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts, USA
    Am J Transplant 6:2743-9. 2006
    ..5% and 73.9%, respectively. Most subjects retransplanted after PTLD are <17 years on TAC-based immunosuppression. Patient/graft survival is excellent and retransplantation in PTLD subjects should be considered acceptable...
  26. ncbi request reprint A single center experience with extrahepatic cholangiocarcinomas
    S R Johnson
    Department of Surgery, Division of Transplantation, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267-0558, USA
    Surgery 130:584-90; discussion 590-2. 2001
    ..5% chance of a curative surgical resection, achieving a 5-year survival rate of 44.4%. Only the absence of a portal mass was predictive of a possible curative resection and long-term survival...
  27. ncbi request reprint Who pays for biliary complications following liver transplant? A business case for quality improvement
    M J Englesbe
    Department of Surgery, Division of Transplantation, University of Michigan Health System, Ann Arbor, Michigan, USA
    Am J Transplant 6:2978-82. 2006
    ..Medical centers have a financial interest in transplant surgical quality improvement, but payers have the most to gain with improved surgical outcomes...
  28. ncbi request reprint Enteric drainage of a pancreas allograft is safe for patients with celiac sprue
    Mohamed Akoad
    Department of Surgery, Division of Transplantation, The Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA
    Clin Transplant 16:387-8. 2002
    ..We believe that, when carefully performed, enteric drainage of pancreas allografts is a safe approach for diabetic patients with celiac sprue, and may avert the serious complications associated with bladder drainage...
  29. doi request reprint Roux limb volvulus after pancreas transplantation: an unusual cause of pancreatic graft loss
    Martin J Dib
    Division of Transplantation, Department of Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA
    Clin Transplant 23:807-11. 2009
    ..Potential bowel complications related to the sigmoid mesentery in left-sided pancreas transplantation are additional reasons for right-sided placement of the pancreas allograft...
  30. ncbi request reprint Multi-detector row CT of relevant vascular anatomy of the surgical plane in split-liver transplantation
    Michael J Guiney
    Department of Radiology, Beth Israel Deaconess Medical Center Harvard Medical School, One Deaconess Road, Boston, MA 02215, USA
    Radiology 229:401-7. 2003
    ..To evaluate relevant arterial and venous anatomy of the hepatectomy plane lateral to segment IV by using multi-detector row computed tomography (CT) with respect to adult living related transplantation of the right lobe of the liver...
  31. ncbi request reprint Increased biliary fistulas after liver resection with the harmonic scalpel
    Joseph Kim
    Department of Surgery, University of Cincinnati College of Medicine, Cincinnati, Ohio 45219, USA
    Am Surg 69:815-9. 2003
    ..Its use was also associated with a significant increase in the incidence of postoperative bile leaks, and, therefore, surgeons must be vigilant during liver parenchymal transection when using this device...
  32. ncbi request reprint Tumors and transplantation: The 2003 Third Annual ASTS State-of-the-Art Winter Symposium
    Sandy Feng
    Division of Transplantation, Department of Surgery, University of California San Francisco, USA
    Am J Transplant 3:1481-7. 2003
  33. ncbi request reprint Organ donors with positive viral serology or malignancy: risk of disease transmission by transplantation
    Sandy Feng
    Department of Surgery, Division of Transplantation, University of California, San Francisco, San Francisco, CA 94143 0780, USA
    Transplantation 74:1657-63. 2002
  34. ncbi request reprint Atypical radiological presentation of progressive multifocal leukoencephalopathy following liver transplantation
    Marco A Lima
    Department of Neurology, Division of Viral Pathogenesis, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA
    J Neurovirol 11:46-50. 2005
    ..The authors report an atypical presentation of PML with contrast-enhancing lesions and mass effect on the MRI in a liver transplant recipient,who had a progressive course and fatal outcome...
  35. ncbi request reprint Deceased donors with a past history of malignancy: an organ procurement and transplantation network/united network for organ sharing update
    H Myron Kauffman
    Research Department, United Network for Organ Sharing, Richmond, VA 23219, USA
    Transplantation 84:272-4. 2007
    ..Donors with a past history of cancer who have a nontraumatic cerebral hemorrhage cause concern because this hemorrhage may be the result of an unrecognized metastatic tumor...
  36. ncbi request reprint Post-transplant de novo malignancies in renal transplant recipients: the past and present
    H Myron Kauffman
    Research Department, United Network for Organ Sharing, Richmond, VA 23219, USA
    Transpl Int 19:607-20. 2006
    ..The substantial role that de novo malignancies play in post-transplant mortality is discussed. Finally, management recommendations for recipients who develop de novo post-transplant malignancies are briefly presented...
  37. ncbi request reprint Association of the type of induction immunosuppression with posttransplant lymphoproliferative disorder, graft survival, and patient survival after primary kidney transplantation
    Wida S Cherikh
    Research Department, United Network for Organ Sharing, Richmond, VA, USA
    Transplantation 76:1289-93. 2003
    ..The authors investigated the incidence of PTLD after monoclonal antilymphocyte, polyclonal antilymphocyte, interleukin (IL)-2 receptor antibody, or no induction therapy in primary kidney transplant recipients...
  38. ncbi request reprint Liver and intestine transplantation
    Robert S Brown
    Columbia University College of Physicians and Surgeons, New York, NY, USA
    Am J Transplant 4:81-92. 2004
    ..As this procedure matures, its application may increase to include recipients at an earlier stage of their disease with better likelihood of success...
  39. ncbi request reprint Maintenance immunosuppression with target-of-rapamycin inhibitors is associated with a reduced incidence of de novo malignancies
    H Myron Kauffman
    Research Department, United Network for Organ Sharing, Richmond, VA, USA
    Transplantation 80:883-9. 2005
    ..In animal models, calcineurin inhibitors have a positive growth effect, whereas target-of-rapamycin (TOR) inhibitors have a negative growth effect on malignant cells...
  40. ncbi request reprint Retransplantation after post-transplant lymphoproliferative diseases (PTLD): when is it safe?
    Douglas W Hanto
    Am J Transplant 4:1733-4. 2004
  41. ncbi request reprint Association of type of induction with posttransplant lymphoproliferative disorders
    Douglas W Hanto
    Am J Transplant 4:1552. 2004