Chris Halpin

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. pmc Audiology in the sudden hearing loss clinical trial
    Chris Halpin
    Department of Audiology, Massachusetts Eye and Ear Infirmary, USA
    Otol Neurotol 33:907-11. 2012
  2. doi request reprint Improvement in word recognition score with level is associated with hearing aid ownership among patients with hearing loss
    Chris Halpin
    Department of Audiology, Massachusetts Eye and Ear Infirmary, Boston, USA
    Audiol Neurootol 17:139-47. 2012
  3. pmc Suggested response criteria for phase II antitumor drug studies for neurofibromatosis type 2 related vestibular schwannoma
    Scott R Plotkin
    Department of Neurology and Cancer Center, Massachusetts General Hospital, Boston, MA 02114, USA
    J Neurooncol 93:61-77. 2009
  4. doi request reprint Hearing aids and cochlear damage: the case against fitting the pure tone audiogram
    Chris Halpin
    Department of Audiology, Massachusetts Eye and Ear Infirmary, Boston, MA, USA
    Otolaryngol Head Neck Surg 140:629-32. 2009
  5. doi request reprint Clinical implications of a damaged cochlea: pure tone thresholds vs information-carrying capacity
    Chris Halpin
    Department of Audiology, Massachusetts Eye and Ear Infirmary, Boston, MA 02114, USA
    Otolaryngol Head Neck Surg 140:473-6. 2009
  6. pmc Hearing and facial function outcomes for neurofibromatosis 2 clinical trials
    Scott R Plotkin
    From the Neurology Department and Cancer Center S R P and Neurosurgical Service F G B, Massachusetts General Hospital, Boston, MA Department of Neurology and Neurosurgery S L A H, The Children s Hospital at Westmead, University of Sydney, Australia Department of Neurology and Oncology J O B, John Hopkins Medical Institute, Baltimore, MD University Department of Medical Genetics D G E, St Mary s Hospital, Manchester, UK Department of Neurology R E F, Guy s and St Thomas NHS Foundation Trust and Institute of Psychiatry, King s College London, UK Department of Otolaryngology T A H and Audiology C H, Massachusetts Eye and Ear Infirmary and Harvard Medical School T A H, Boston, MA
    Neurology 81:S25-32. 2013
  7. doi request reprint Twenty years of audiology in a patient with Norrie disease
    Chris Halpin
    Department of Audiology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, 243 Charles Street, Boston, MA 02114, United States
    Int J Pediatr Otorhinolaryngol 72:1705-10. 2008
  8. doi request reprint Bevacizumab for progressive vestibular schwannoma in neurofibromatosis type 2: a retrospective review of 31 patients
    Scott R Plotkin
    Department of Neurology and Cancer Center, Massachusetts General Hospital, Boston 02114, USA
    Otol Neurotol 33:1046-52. 2012
  9. ncbi request reprint Hearing improvement after bevacizumab in patients with neurofibromatosis type 2
    Scott R Plotkin
    Department of Neurology, Massachusetts General Hospital, Boston, MA 02114, USA
    N Engl J Med 361:358-67. 2009
  10. ncbi request reprint Using audiometric thresholds and word recognition in a treatment study
    Chris Halpin
    Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts 02114, USA
    Otol Neurotol 27:110-6. 2006

Detail Information

Publications11

  1. pmc Audiology in the sudden hearing loss clinical trial
    Chris Halpin
    Department of Audiology, Massachusetts Eye and Ear Infirmary, USA
    Otol Neurotol 33:907-11. 2012
    ..To report the pretreatment and posttreatment population characteristics and the overall stability of the audiologic outcomes found during the Sudden Hearing Loss Clinical Trial (ClinicalTrials.gov: Identifier NCT00097448)...
  2. doi request reprint Improvement in word recognition score with level is associated with hearing aid ownership among patients with hearing loss
    Chris Halpin
    Department of Audiology, Massachusetts Eye and Ear Infirmary, Boston, USA
    Audiol Neurootol 17:139-47. 2012
    ....
  3. pmc Suggested response criteria for phase II antitumor drug studies for neurofibromatosis type 2 related vestibular schwannoma
    Scott R Plotkin
    Department of Neurology and Cancer Center, Massachusetts General Hospital, Boston, MA 02114, USA
    J Neurooncol 93:61-77. 2009
    ..We encourage adoption of standardized endpoints early in the development of phase II trials for this population to facilitate comparison of results across trials of different agents...
  4. doi request reprint Hearing aids and cochlear damage: the case against fitting the pure tone audiogram
    Chris Halpin
    Department of Audiology, Massachusetts Eye and Ear Infirmary, Boston, MA, USA
    Otolaryngol Head Neck Surg 140:629-32. 2009
    ..We recommend that it is better to accommodate the damaged cochlea in these cases than to attempt to reverse-engineer the audiometric test results...
  5. doi request reprint Clinical implications of a damaged cochlea: pure tone thresholds vs information-carrying capacity
    Chris Halpin
    Department of Audiology, Massachusetts Eye and Ear Infirmary, Boston, MA 02114, USA
    Otolaryngol Head Neck Surg 140:473-6. 2009
    ..We argue that word recognition testing at low vs high presentation levels provides a quantification of the cochlea's information-carrying capacity and is a useful predictor of word recognition limits with hearing aids...
  6. pmc Hearing and facial function outcomes for neurofibromatosis 2 clinical trials
    Scott R Plotkin
    From the Neurology Department and Cancer Center S R P and Neurosurgical Service F G B, Massachusetts General Hospital, Boston, MA Department of Neurology and Neurosurgery S L A H, The Children s Hospital at Westmead, University of Sydney, Australia Department of Neurology and Oncology J O B, John Hopkins Medical Institute, Baltimore, MD University Department of Medical Genetics D G E, St Mary s Hospital, Manchester, UK Department of Neurology R E F, Guy s and St Thomas NHS Foundation Trust and Institute of Psychiatry, King s College London, UK Department of Otolaryngology T A H and Audiology C H, Massachusetts Eye and Ear Infirmary and Harvard Medical School T A H, Boston, MA
    Neurology 81:S25-32. 2013
    ..Although hearing loss and facial weakness have been identified as important functional outcomes for patients with NF2, there is a lack of consensus regarding appropriate endpoints in clinical trials...
  7. doi request reprint Twenty years of audiology in a patient with Norrie disease
    Chris Halpin
    Department of Audiology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, 243 Charles Street, Boston, MA 02114, United States
    Int J Pediatr Otorhinolaryngol 72:1705-10. 2008
    ..Affected individuals are born blind and develop progressive sensory loss with onset in adolescence. This disease is X-linked and has been associated with mutations of the NDP gene (Xp11.4)...
  8. doi request reprint Bevacizumab for progressive vestibular schwannoma in neurofibromatosis type 2: a retrospective review of 31 patients
    Scott R Plotkin
    Department of Neurology and Cancer Center, Massachusetts General Hospital, Boston 02114, USA
    Otol Neurotol 33:1046-52. 2012
    ..The aim of this study was to report extended follow-up in a larger cohort of similarly treated patients...
  9. ncbi request reprint Hearing improvement after bevacizumab in patients with neurofibromatosis type 2
    Scott R Plotkin
    Department of Neurology, Massachusetts General Hospital, Boston, MA 02114, USA
    N Engl J Med 361:358-67. 2009
    ..There is no medical treatment for such tumors...
  10. ncbi request reprint Using audiometric thresholds and word recognition in a treatment study
    Chris Halpin
    Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts 02114, USA
    Otol Neurotol 27:110-6. 2006
    ..Second, to examine the outcomes when using two different types of criteria for significant change in a subject's word recognition score...
  11. doi request reprint Audiologic and radiographic response of NF2-related vestibular schwannoma to erlotinib therapy
    Scott R Plotkin
    Department of Neurology, Massachusetts General Hospital, 55 Fruit Street, Yawkey 9E, Boston, MA 02114, USA
    Nat Clin Pract Oncol 5:487-91. 2008
    ..A 48-year-old man presented to a neurologist with complaints of bilateral hearing loss and tinnitus. The patient was a member of a large family affected by neurofibromatosis type 2 and first noted hearing loss 10 years before presentation...