Marcia HaigisSummaryAffiliation: Harvard University Country: USA Publications
Research Grants
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Detail Information
Publications
The coordination of nuclear and mitochondrial communication during aging and calorie restrictionLydia W S Finley
The Paul F Glenn Labs for the Biological Mechanisms of Aging, Department of Pathology, Harvard Medical School, Boston, MA 02115, USA
Ageing Res Rev 8:173-88. 2009..Greater understanding of the mechanisms by which mitochondria and the nucleus communicate will facilitate efforts to slow or reverse the mitochondrial dysfunction that occurs during aging...
Mammalian sirtuins: biological insights and disease relevanceMarcia C Haigis
Glenn Laboratories for the Molecular Biology of Aging, Department of Pathology, Harvard Medical School, Boston, Massachusetts 02115, USA
Annu Rev Pathol 5:253-95. 2010..This review summarizes and discusses the advances of the past decade and the challenges that will confront the field in the coming years...
The aging stress responseMarcia C Haigis
Department of Pathology, Harvard Medical School, Boston, MA 02115, USA
Mol Cell 40:333-44. 2010..The systems biology of stress response signaling thus provides a new approach to the understanding and potential treatment of age-related diseases...
Role of sirtuins and calorie restriction in neuroprotection: implications in Alzheimer's and Parkinson's diseasesSarika Srivastava
The Paul F Glenn Labs for the Biological Mechanisms of Aging, Department of Pathology, Harvard Medical School, Boston, MA 02115, USA
Curr Pharm Des 17:3418-33. 2011....
Sirtuins regulate key aspects of lipid metabolismDavid J Lomb
Department of Pathology and Paul F Glenn Laboratories for the Biological Mechanisms of Aging, Harvard Medical School, Boston, MA 02115, USA
Biochim Biophys Acta 1804:1652-7. 2010..These findings suggest that sirtuins might provide important new targets for the treatment of obesity and related diseases. In this review, we discuss the major findings linking sirtuins with the regulation of lipid metabolism...
Research Grants
- Regulation of mitochondrial metabolism by SIRT4Marcia Haigis; Fiscal Year: 2009..These studies have the potential to lead to new treatments of diet and age-associated metabolic syndrome. ..
- Regulation of mitochondrial metabolism by SIRT4Marcia Haigis; Fiscal Year: 2010..These studies have the potential to lead to new treatments of diet and age-associated metabolic syndrome. ..
