Nouchine Hadjikhani

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. ncbi request reprint Early visual cortex organization in autism: an fMRI study
    Nouchine Hadjikhani
    Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Bldg 36, First Street, Room 417, Charlestown, MA 02129, USA
    Neuroreport 15:267-70. 2004
  2. pmc Emotional contagion for pain is intact in autism spectrum disorders
    N Hadjikhani
    1 Brain Mind Institute, EPFL, Lausanne, Switzerland 2 Gillberg Neuropsychiatry Centre, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden 3 Athinoula A Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA, USA
    Transl Psychiatry 4:e343. 2014
  3. pmc It's all in the eyes: subcortical and cortical activation during grotesqueness perception in autism
    Nicole R Zürcher
    Brain Mind Institute, EPFL, Lausanne, Switzerland
    PLoS ONE 8:e54313. 2013
  4. pmc Early category-specific cortical activation revealed by visual stimulus inversion
    Hanneke K M Meeren
    Cognitive and Affective Neuroscience Laboratory, Tilburg University, Tilburg, The Netherlands
    PLoS ONE 3:e3503. 2008
  5. pmc A 7 tesla FMRI study of amygdala responses to fearful faces
    Wietske van der Zwaag
    Department of Radiology, University of Lausanne, Switzerland
    Brain Topogr 25:125-8. 2012
  6. ncbi request reprint Retinotopy and color sensitivity in human visual cortical area V8
    N Hadjikhani
    Nuclear Magnetic Resonance Center, Massachusetts General Hospital, Charlestown 02129, USA
    Nat Neurosci 1:235-41. 1998
  7. pmc Pointing with the eyes: the role of gaze in communicating danger
    Nouchine Hadjikhani
    Athinoula A Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA
    Brain Cogn 68:1-8. 2008
  8. pmc Early (M170) activation of face-specific cortex by face-like objects
    Nouchine Hadjikhani
    MGH MIT HMS Athinoula A Martinos Center for Biomedical Imaging, Charlestown, MA 02129, USA
    Neuroreport 20:403-7. 2009
  9. ncbi request reprint Serotonin, pregnancy and increased autism prevalence: is there a link?
    Nouchine Hadjikhani
    MGH MIT HMS Martinos Center for Biomedical Imaging, Charlestown, USA Brain Mind Institute, EPFL Lausanne, Switzerland
    Med Hypotheses 74:880-3. 2010
  10. ncbi request reprint Abnormal activation of the social brain during face perception in autism
    Nouchine Hadjikhani
    Athinoula A Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts 02129, USA
    Hum Brain Mapp 28:441-9. 2007

Research Grants

  1. Visual-social cognition in neurodevelopmental disorders
    Nouchine Hadjikhani; Fiscal Year: 2002
  2. Visual-social cognition in neurodevelopmental disorders
    Nouchine Hadjikhani; Fiscal Year: 2003
  3. Visual-social cognition in neurodevelopmental disorders
    Nouchine Hadjikhani; Fiscal Year: 2004

Detail Information

Publications35

  1. ncbi request reprint Early visual cortex organization in autism: an fMRI study
    Nouchine Hadjikhani
    Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Bldg 36, First Street, Room 417, Charlestown, MA 02129, USA
    Neuroreport 15:267-70. 2004
    ..We conclude that the differences observed in the visual capacities of individuals with autism are likely to arise from higher-level cognitive areas and functions, and are the result of top-down processes...
  2. pmc Emotional contagion for pain is intact in autism spectrum disorders
    N Hadjikhani
    1 Brain Mind Institute, EPFL, Lausanne, Switzerland 2 Gillberg Neuropsychiatry Centre, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden 3 Athinoula A Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA, USA
    Transl Psychiatry 4:e343. 2014
    ..Our findings show that simulation mechanisms involved in emotional empathy are preserved in high-functioning individuals with autism, and suggest that increased reappraisal may have a role in their apparent lack of caring behavior. ..
  3. pmc It's all in the eyes: subcortical and cortical activation during grotesqueness perception in autism
    Nicole R Zürcher
    Brain Mind Institute, EPFL, Lausanne, Switzerland
    PLoS ONE 8:e54313. 2013
    ....
  4. pmc Early category-specific cortical activation revealed by visual stimulus inversion
    Hanneke K M Meeren
    Cognitive and Affective Neuroscience Laboratory, Tilburg University, Tilburg, The Netherlands
    PLoS ONE 3:e3503. 2008
    ....
  5. pmc A 7 tesla FMRI study of amygdala responses to fearful faces
    Wietske van der Zwaag
    Department of Radiology, University of Lausanne, Switzerland
    Brain Topogr 25:125-8. 2012
    ....
  6. ncbi request reprint Retinotopy and color sensitivity in human visual cortical area V8
    N Hadjikhani
    Nuclear Magnetic Resonance Center, Massachusetts General Hospital, Charlestown 02129, USA
    Nat Neurosci 1:235-41. 1998
    ..We also tested the response to stimuli that produce color afterimages and found that these stimuli, like real colors, caused preferential activation of V8 but not V4...
  7. pmc Pointing with the eyes: the role of gaze in communicating danger
    Nouchine Hadjikhani
    Athinoula A Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA
    Brain Cogn 68:1-8. 2008
    ....
  8. pmc Early (M170) activation of face-specific cortex by face-like objects
    Nouchine Hadjikhani
    MGH MIT HMS Athinoula A Martinos Center for Biomedical Imaging, Charlestown, MA 02129, USA
    Neuroreport 20:403-7. 2009
    ..An earlier peak at 130 ms was also seen for images of real faces only. Our findings suggest that face perception evoked by face-like objects is a relatively early process, and not a late reinterpretation cognitive phenomenon...
  9. ncbi request reprint Serotonin, pregnancy and increased autism prevalence: is there a link?
    Nouchine Hadjikhani
    MGH MIT HMS Martinos Center for Biomedical Imaging, Charlestown, USA Brain Mind Institute, EPFL Lausanne, Switzerland
    Med Hypotheses 74:880-3. 2010
    ..If our hypothesis is confirmed, it will not only shed light on one of the possible reason for autism prevalence, but also offer new preventive and treatment options...
  10. ncbi request reprint Abnormal activation of the social brain during face perception in autism
    Nouchine Hadjikhani
    Athinoula A Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts 02129, USA
    Hum Brain Mapp 28:441-9. 2007
    ..These patterns suggest that areas belonging to the mirror neuron system are involved in the face-processing disturbances in ASD...
  11. ncbi request reprint Activation of the fusiform gyrus when individuals with autism spectrum disorder view faces
    Nouchine Hadjikhani
    Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA
    Neuroimage 22:1141-50. 2004
    ....
  12. ncbi request reprint Seeing fearful body expressions activates the fusiform cortex and amygdala
    Nouchine Hadjikhani
    Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA
    Curr Biol 13:2201-5. 2003
    ..Our findings open a new area of investigation of the role of body expressions of emotion in adaptive behavior as well as the relation between processes of emotion recognition in the face and in the body...
  13. ncbi request reprint Neural basis of prosopagnosia: an fMRI study
    Nouchine Hadjikhani
    Nuclear Magnetic Resonance Center, Massachusetts General Hospital, Charlestown 02129, USA
    Hum Brain Mapp 16:176-82. 2002
    ..Our study casts light on the important role of FFA and IOG in the network of areas involved in face recognition, and indicates limits of brain plasticity...
  14. ncbi request reprint Projection of rods and cones within human visual cortex
    N Hadjikhani
    Nuclear Magnetic Resonance Center, Massachusetts General Hospital, Charlestown 02129, USA
    Hum Brain Mapp 9:55-63. 2000
    ..These cortical differences reflect corresponding differences in perception between scotopic and photopic conditions...
  15. pmc Body expressions of emotion do not trigger fear contagion in autism spectrum disorder
    Nouchine Hadjikhani
    Athinoula A Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA, USA
    Soc Cogn Affect Neurosci 4:70-8. 2009
    ..Our data suggest that emotion perception deficits in ASD may be due to compromised processing of the emotional component of observed actions...
  16. pmc Different cortical dynamics in face and body perception: an MEG study
    Hanneke K M Meeren
    Cognitive Neuroscience, Tilburg University, Tilburg, The Netherlands
    PLoS ONE 8:e71408. 2013
    ..Instead, the LOTC, which includes the extra-striate body area (EBA), appears the dominant area for early body perception, whereas the VTC contributes to late and post-perceptual processing. ..
  17. ncbi request reprint Anatomical differences in the mirror neuron system and social cognition network in autism
    Nouchine Hadjikhani
    Athinoula A Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA
    Cereb Cortex 16:1276-82. 2006
    ..These findings suggest that the social and emotional deficits characteristic of autism may reflect abnormal thinning of the MNS and the broader network of cortical areas subserving social cognition...
  18. pmc Response monitoring, repetitive behaviour and anterior cingulate abnormalities in autism spectrum disorders (ASD)
    Katharine N Thakkar
    Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02215, USA
    Brain 131:2464-78. 2008
    ..Illuminating the mechanisms and clinical significance of abnormal response monitoring in ASD represents a fruitful avenue for further research...
  19. ncbi request reprint Non-conscious recognition of emotional body language
    Beatrice de Gelder
    Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts, USA
    Neuroreport 17:583-6. 2006
    ..Our results show that in the absence of the striate cortex implicit bodily emotion perception may be possible...
  20. pmc Interictal alterations of the trigeminal somatosensory pathway and periaqueductal gray matter in migraine
    Alexandre F M DaSilva
    Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts 02129, USA
    Neuroreport 18:301-5. 2007
    ..Our results indicate the presence of permanent interictal changes in migraineurs, pointing to an effect of migraine on the trigeminal somatosensory and modulatory pain systems...
  21. pmc The missing link: enhanced functional connectivity between amygdala and visceroceptive cortex in migraine
    Nouchine Hadjikhani
    Athinoula A Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, MA, USA
    Cephalalgia 33:1264-8. 2013
    ..The role of CSD and amygdala connectivity in migraine without aura (MwoA) is less clear and may differentiate migraine from other chronic pain disorders...
  22. pmc Perception of social cues of danger in autism spectrum disorders
    Nicole R Zürcher
    Brain Mind Institute, EPFL, Lausanne, Switzerland Athinoula A Martinos Center for Biomedical Imaging, Harvard Medical School, Massachusetts General Hospital, Charlestown, Massachusetts, United States of America
    PLoS ONE 8:e81206. 2013
    ..Our data suggest that individuals with ASD are more sensitive to direct eye contact than to social signals of danger conveyed by averted fearful gaze. ..
  23. doi request reprint In-vivo magnetic resonance imaging of the structural core of the Papez circuit in humans
    Cristina Granziera
    Department of Neurology, Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland
    Neuroreport 22:227-31. 2011
    ..The diagnostic and therapeutic implications of these results are discussed in the context of recent findings reporting the involvement of the Papez circuit in neurological and psychiatric diseases...
  24. pmc Anatomical alterations of the visual motion processing network in migraine with and without aura
    Cristina Granziera
    Athinoula A Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts, United States of America
    PLoS Med 3:e402. 2006
    ..Moreover, the diagnosis of migraine relies on patient's history, and finding differences in the brain of migraineurs might help to contribute to basic research aimed at better understanding the pathophysiology of migraine...
  25. pmc Thickening in the somatosensory cortex of patients with migraine
    Alexandre F M DaSilva
    Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Bldg 36, First St, Room 417, Charlestown, MA 02129, USA
    Neurology 69:1990-5. 2007
    ..To examine morphologic changes in the somatosensory cortex (SSC) of patients with migraine...
  26. pmc A modulatory role for facial expressions in prosopagnosia
    Beatrice de Gelder
    Cognitive and Affective Neurosciences Laboratory, Tilburg University, 5000 LA Tilburg, The Netherlands
    Proc Natl Acad Sci U S A 100:13105-10. 2003
    ..This finding suggests a modulatory role of these areas in face identification that is independent of occipitotemporal face areas...
  27. pmc Altered functional magnetic resonance imaging resting-state connectivity in periaqueductal gray networks in migraine
    Caterina Mainero
    Athinoula A Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA, USA
    Ann Neurol 70:838-45. 2011
    ..The aim of this study was to examine functional connectivity of the PAG in migraine...
  28. pmc Fear fosters flight: a mechanism for fear contagion when perceiving emotion expressed by a whole body
    Beatrice de Gelder
    Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, First Street Building 36, Charlestown, MA 02129, USA
    Proc Natl Acad Sci U S A 101:16701-6. 2004
    ..The mechanism of fear contagion hereby suggested may automatically prepare the brain for action...
  29. pmc Diffusion spectrum imaging shows the structural basis of functional cerebellar circuits in the human cerebellum in vivo
    Cristina Granziera
    Department of Neurology, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland
    PLoS ONE 4:e5101. 2009
    ..Identifying the structural bases of cerebellar neuronal networks in humans in vivo may provide biomarkers for diagnosis and management of cerebellar diseases...
  30. doi request reprint Structural abnormalities in the thalamus of migraineurs with aura: a multiparametric study at 3 T
    Cristina Granziera
    GRHAD, BMI, SV, EPFL, Lausanne, Switzerland Laboratoire de Recherche en Neuroimagerie and Neuroimmunology Unit, Department of Clinical Neurosciences, Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland Advanced Clinical Imaging Technology Group, Siemens CIBM, EPFL, Lausanne, Switzerland
    Hum Brain Mapp 35:1461-8. 2014
    ..This work aimed at studying the microstructure of the thalamus in migraine patients using an innovative multiparametric approach at high-field magnetic resonance imaging (MRI)...
  31. pmc Investigating gaze of children with ASD in naturalistic settings
    Basilio Noris
    Learning Algorithms and Systems Laboratory, Ecole Polytechnique Federale de Lausanne, Lausanne, Switzerland
    PLoS ONE 7:e44144. 2012
    ..In this study we focused on i) whether the findings done in laboratory settings are also visible in a naturalistic interaction; ii) whether new atypical elements appear when studying visual behavior across the whole field of view...
  32. ncbi request reprint A primer on diffusion tensor imaging of anatomical substructures
    Alexandre F M DaSilva
    Martinos Center for Biomedical Imaging, Massachusetts General Hospital, NMR Center, Harvard Medical School, Charlestown, Massachusetts 02129, USA
    Neurosurg Focus 15:E4. 2003
    ..The authors illustrate how DT imaging can resolve individual pathways in the brainstem as well as individual nuclei of the thalamus and conclude by describing potential applications in neurosurgery...
  33. pmc Statistical group comparison of diffusion tensors via multivariate hypothesis testing
    Brandon Whitcher
    Clinical Imaging Centre, GlaxoSmithKline, Hammersmith Hospital, London, UK
    Magn Reson Med 57:1065-74. 2007
    ..When applying the Cramér test of the diffusion tensor in a clinical population with a history of migraine, a 169% increase was observed in the volume of a significant cluster compared to the univariate FA test...
  34. pmc Relevance of cortical thickness in migraine sufferers
    Nouchine Hadjikhani
    Expert Rev Neurother 8:327-9. 2008

Research Grants3

  1. Visual-social cognition in neurodevelopmental disorders
    Nouchine Hadjikhani; Fiscal Year: 2002
    ..It should give us additional insight into the pathophysiology face perception disorders, and provide a basis for the development of remedial treatment for deficits in social communication. ..
  2. Visual-social cognition in neurodevelopmental disorders
    Nouchine Hadjikhani; Fiscal Year: 2003
    ..It should give us additional insight into the pathophysiology face perception disorders, and provide a basis for the development of remedial treatment for deficits in social communication. ..
  3. Visual-social cognition in neurodevelopmental disorders
    Nouchine Hadjikhani; Fiscal Year: 2004
    ..It should give us additional insight into the pathophysiology face perception disorders, and provide a basis for the development of remedial treatment for deficits in social communication. ..