Affiliation: Harvard University
- Life is a journey: a genetic look at neocortical developmentAmitabh Gupta
Department of Pathology, Harvard Medical School, Howard Hughes Medical Institute, 200 Longwood Avenue, Boston, Massachusetts 02115, USA
Nat Rev Genet 3:342-55. 2002..The challenge of current research is to understand the manner in which these various signalling pathways are interconnected to gain a more comprehensive picture of the molecular intricacies that govern neocortical development...
- Disabled-1-regulated adhesion of migrating neurons to radial glial fiber contributes to neuronal positioning during early corticogenesisKamon Sanada
Department of Pathology, Harvard Medical School, 77 Avenue Louis Pasteur, Boston, MA 02115, USA
Neuron 42:197-211. 2004..Altogether, these results outline the molecular mechanism by which Disabled-1 signaling controls the adhesive property of neurons to radial glia, thereby maintaining proper neuronal positioning during corticogenesis...
- Cyclin-dependent kinase 5 and neuronal migration in the neocortexAmitabh Gupta
Department of Pathology, Harvard Medical School and Howard Hughes Medical Institute, Boston, Mass. 02115, USA
Neurosignals 12:173-9. 2003....
- Layering defect in p35 deficiency is linked to improper neuronal-glial interaction in radial migrationAmitabh Gupta
Department of Pathology, Harvard Medical School and Howard Hughes Medical Institute, Boston, Massachusetts 02115, USA
Nat Neurosci 6:1284-91. 2003..Hence, our findings suggest that inside-out layering requires distinct functions of Reelin and p35/Cdk5 signaling, with the latter being important for proper glia-guided migration...