John G Gunderson

..This report investigates the longitudinal association of changes in major depressive disorder (MDD) and borderline personality disorder...

..The purpose of this article is to describe the development of the borderline personality disorder diagnosis, highlighting both the obstacles encountered and the associated achievements...

..The primary purpose of this report was to investigate whether characteristics of subjects with borderline personality disorder observed at baseline can predict variations in outcome at the 2-year follow-up...

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..Borderline personality disorder (BPD) is traditionally considered chronic and intractable...

..In addition, they support an association between severity of PD and severity of traumatic exposure, as indicated by earlier trauma onset, trauma of an assaultive and personal nature, and more types of traumatic events...

..To examine prospectively the course of major depressive disorder (MDD) and to test for the moderating effects of personality disorder (PD) comorbidity on relapse after remission from an episode of MDD...

..These PDs emerged as robust predictors of slowed remission from MDD even when controlling for other negative prognostic predictors...

..The purpose of this study was to examine whether patients with borderline personality disorder (BPD) have a higher rate of new onsets of substance use disorders (SUD) than do patients with other personality disorders (OPD)...

..The eating disorders met criteria outlined in the 4th edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-IV)...

..Dimensionally, these findings suggest that PDs may be characterized by maladaptive trait constellations that are stable in their structure (individual differences) but can change in severity or expression over time...

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..The factors contributing to these differences warrant further investigation...

..To examine the longitudinal diagnostic efficiency of the DSM-IV criteria for borderline personality disorder (BPD)...

..To examine prospectively the natural course of bulimia nervosa and eating disorder not otherwise specified (EDNOS) and to test for the effects of personality disorder psychopathology on remission and relapse...

..CONCLUSIONS: These results suggest that early manifestations of AVPD are present in childhood but that various forms of abuse are not specific to the disorder...

..In conclusion, patients with BPD can make significant improvements that are rapid and of sufficient duration to be considered remissions. Determinants were identified that warrant further prospective evaluation...

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..The findings may be relevant for understanding the core interpersonal psychopathology of BPD and for managing therapeutic relationships with these patients...

..A combination of preoccupied and fearful self-reported attachment styles is more specific to BPD than either style alone or attachment insecurity in general...

..Research elucidating the relationship between reflective function, overlapping concepts, and features of borderline psychopathology is needed...

..Some implications from this gene-environment interactional theory for a better developmental understanding of BPD's etiology are discussed...

..The familiality of borderline personality disorder (BPD) and its sectors of psychopathology are incompletely understood...

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..In contrast, MACT did not affect the level of suicide ideation and time-to-repeat of DSH. In conclusion, MACT seems to be a promising intervention for DSH in patients with BPD. More definitive studies are needed...

..The results of this study suggest that a sizable minority of borderline patients first engage in self-harm as children and that the course of their self-mutilation may be particularly malignant...

..Clinical data indicate that accurately diagnosing and treating BPD conserves resources and improves outcomes. Based on this analysis, insuring BPD in the same manner as other serious mental illnesses is well-founded and recommended...

..While these preliminary results are promising, the study's limitations require their replication in a larger-scale randomized controlled trial...

..Taken together, the results of this study suggest that the subsyndromal phenomenology of BPD may be more common than the borderline diagnosis itself...

..Although there are a number of competing models of personality structure, they have remarkable convergence on a set of three to five basic personality dimensions...

..The use of laboratory paradigms for measures of aggression and affective instability are discussed in the context of such endophenotypic approaches...

..Because of significant methodological problems, most notably indirect assessments and inadequate sample size, major questions persist about the familial aggregation of this disorder that require more definitive methods...

..These changes are incremental, diminish overlap and heterogeneity, sustain clinical and research development, and will improve utilization...

..A greater number of controlled studies are necessary to confirm these impressions. A multisite process and outcome study is proposed...

..Consistent with other research, the findings suggest that PTSD does not appear to alter the central features of BPD. The clinical implications of our findings are considered...

..Furthermore, the model appeared to successfully distinguish specific PDs, a property that represents a particular challenge for dimensional models of personality...

..Therefore, among individuals diagnosed with PDs. exacerbation of Axis I conditions, particularly MDD and substance use, heightens risk for a suicide attempt...

..For example, no difference was found in rates of major depressive disorder, a condition that is more prevalent in females. Thus, BPD pathology may be a prevailing characterization that can attenuate usual gender-based distinctions...

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..This study tested the factor structure of the DSM-IV criteria for borderline personality disorder by using confirmatory methods for the analysis of covariance structures in a large group from a multisite study...

..CONCLUSIONS: Personality disorders are a significant source of psychiatric morbidity, accounting for more impairment in functioning than major depressive disorder alone...

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..Differences between personality disorders may reflect diverse interactions among the dimensions, rather than differences on single dimensions...

..CONCLUSION: Support is provided for the DSM-IV disorder-level classification for schizotypal, borderline, avoidant and obsessive-compulsive personality disorders in a treatment-seeking sample...

..Findings suggest the need to further explore the role of AS in the pathogenesis of BPD...

..However, even when controlling for the effect of borderline PD, other PD diagnoses were associated with specific types of maltreatment...

..The data suggest that personality traits are significant and equally relevant predictors of functioning for both groups. The utility of assessing personality traits for individuals with both Axis I and II disorders is thus supported...

..Therefore, certain types of negative life events are unique risk factors for imminent suicide attempts among individuals with PDs...

..Two of the four personality disorders under examination (STPD and OCPD) showed little or no association with Axis I disorders...

..This study tracked the individual criteria of four DSM-IV personality disorders-borderline, schizotypal, avoidant, and obsessive-compulsive personality disorders-and how they change over 2 years...

..72 across 4 disorders), and reasonably specific to that syndrome relative to the other disorders. The results support the validity of these criterion sets as representing coherent syndromes...

..CONCLUSIONS: Co-occurring PDs contribute significantly to impairment in social and emotional functioning and reduced well-being in patients with MDD...

..Taken together, our results lead us to hypothesize that PDs may be reconceptualized as hybrids of stable personality traits and intermittently expressed symptomatic behaviors...

..Since major depressive disorder did not significantly predict suicidal behaviors, the reactivity associated with affective instability (more so than negative mood states) appears to be a critical element in predicting suicidal behaviors...

..This study compared three-dimensional representations of DSM-IV personality disorders and standard categories with respect to their associations with psychosocial functioning...

..Results highlight directions for future research and suggest that particular aspects of emotion dysregulation may be more or less relevant to BPD...

..The categorical classification system for personality disorder (PD) has been frequently criticized and several alternative dimensional models have been proposed...

..This report describes the effects of persistent and remitting comorbid personality disorders on the depressive status and functioning of patients with major depressive disorder over the course of 2 years...

..The authors attempted to replicate findings of Klein and Shih in longitudinally followed patients with personality disorder or major depressive disorder (MDD) in the Collaborative Longitudinal Personality Disorders Study...

..The results suggest that most of the diagnostic criteria examined do not seem to display sex bias. However, those criteria that displayed evidence of bias came largely from the borderline diagnosis...

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..Preliminary data on symptom changes among patients with BPD during the first 3 months of treatment in a step-down treatment program are presented...

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..Future studies need to assess specific barriers to adequate and appropriate treatments for minority individuals with PDs...

..The purpose of this study was to prospectively investigate the association between positive childhood experiences related to resiliency and remission from personality disorder...

..This paper describes the linguistic adaptation and psychometric validation into Spanish of the Diagnostic Interview for Borderlines-Revised (DIB-R) scale for diagnosing borderline personality disorder (BPD)...

..The validating approach will examine the homogenetic of descriptive and longitudinal features for the PDs, as defined by the DSM system, and how this compares with alternative schemes. ..

..Finally, we will use this study's sample to develop a gene bank for future exploration of genetic associations with BPD and its phenotypic traits. ..

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..The predictive approach will identify clinically meaningful determinants of prognosis within and across PDs. The validating approach will examine the homogeneity of descriptive and longitudinal features for the PDs. ..

..Finally, we will use this study's sample to develop a gene bank for future exploration of genetic associations with BPD and its phenotypic traits. ..