Research Topics
| S GrinspoonSummaryAffiliation: Harvard University Country: USA Publications
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Detail Information
Publications
Effects of fasting and glucose infusion on basal and overnight leptin concentrations in normal-weight womenS K Grinspoon
Department of Pathology, Massachusetts General Hospital, Boston, USA
Am J Clin Nutr 66:1352-6. 1997..05). These data show the sensitivity of plasma leptin concentrations to small changes in energy supply and suggest a basic role of substrate metabolism in the short-term regulation of leptin...- Determinants of increased energy expenditure in HIV-infected womenS Grinspoon
Neuroendocrine Unit, General Clinical Research Center, Massachusetts General Hospital and Harvard Medical School, Boston 02114, USA
Am J Clin Nutr 68:720-5. 1998..Little is known about sex-specific effects of HIV infection on energy expenditure... - Severity of osteopenia in estrogen-deficient women with anorexia nervosa and hypothalamic amenorrheaS Grinspoon
Neuroendocrine Unit, Massachusetts General Hospital and Harvard Medical School, Boston 02114, USA
J Clin Endocrinol Metab 84:2049-55. 1999..Lean body mass, independent of the duration or severity of estrogen deficiency, is an important predictor of bone loss among women with AN... - Assessment of growth hormone dynamics in human immunodeficiency virus-related lipodystrophyP Rietschel
Neuroendocrine Unit, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, USA
J Clin Endocrinol Metab 86:504-10. 2001..Increased visceral adiposity is the strongest predictor of reduced GH concentrations in HIV lipodystrophy. Further studies are necessary to determine the clinical significance of reduced GH in patients with HIV lipodystrophy... - Sustained anabolic effects of long-term androgen administration in men with AIDS wastingS Grinspoon
Infectious Disease Unit, and General Clinical Research Center, Massachusetts General Hospital and Harvard Medical School, Boston 02114, USA
Clin Infect Dis 28:634-6. 1999..7 +/- 0.8 kg vs. 1.0 +/- 1.0 kg; P = .05). Testosterone administration results in sustained increases in LBM during 1 year of therapy in hypogonadal men with AIDS wasting... - Modifiable dietary habits and their relation to metabolic abnormalities in men and women with human immunodeficiency virus infection and fat redistributionC Hadigan
Neuroendocrine Unit, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
Clin Infect Dis 33:710-7. 2001..Polyunsaturated fats, fiber, and alcohol are strongly associated with insulin resistance and hyperlipidemia in this population and may be important targets for dietary modification... - Reduced bone density in androgen-deficient women with acquired immune deficiency syndrome wastingJ S Huang
Neuroendocrine Unit, Massachusetts General Hospital, and Harvard Medical School, Boston, Massachusetts 02114, USA
J Clin Endocrinol Metab 86:3533-9. 2001..Anabolic strategies to increase muscle mass may be useful to increase bone density among osteopenic women with acquired immune deficiency syndrome wasting... - Increased abdominal visceral fat is associated with reduced bone density in HIV-infected men with lipodystrophyJ S Huang
Neuroendocrine Unit, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
AIDS 15:975-82. 2001..Further studies are needed to determine the mechanisms of osteopenia in HIV lipodystrophy and whether increased marrow fat occurs in such patients and affects bone density... - Effects of testosterone and exercise on muscle leanness in eugonadal men with AIDS wastingW P Fairfield
Neuroendocrine Unit, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, USA
J Appl Physiol 90:2166-71. 2001..These data demonstrate that thigh muscle attenuation by computed tomography varies inversely with whole body fat and increases with testosterone and training. Anabolic therapy in these patients increases muscle leanness... - Changes in regional fat redistribution and the effects of estrogen during spontaneous weight gain in women with anorexia nervosaS Grinspoon
Neuroendocrine Unit, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA
Am J Clin Nutr 73:865-9. 2001..Anorexia nervosa is a disease of severe acquired undernutrition with a high and increasing prevalence among young women in the United States... - Mechanisms of androgen deficiency in human immunodeficiency virus-infected women with the wasting syndromeS Grinspoon
Neuroendocrine Unit, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, USA
J Clin Endocrinol Metab 86:4120-6. 2001..Further studies of the mechanism of adrenal steroid shunting and the efficacy of androgen replacement in human immunodeficiency virus-infected women are necessary... - Preservation of neuroendocrine control of reproductive function despite severe undernutritionK K Miller
Neuroendocrine Unit, BUL 457B, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
J Clin Endocrinol Metab 89:4434-8. 2004..In addition, nutritional intake and normal hormonal function may be independent contributors to maintenance of trabecular bone mass in low-weight women... - Insulin resistance in the HIV-lipodystrophy syndromeS Grinspoon
Neuroendocrine Unit, Massachusetts General Hospital, Boston, MA 02114, USA
Trends Endocrinol Metab 12:413-9. 2001..Furthermore, insulin-sensitizing agents might improve insulin resistance and reduce the risk of CVD in this population... - Diagnosis and treatment of androgen deficiency in human immunodeficiency virus-infected men and womenE Mylonakis
Infectious Disease Division, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
Clin Infect Dis 33:857-64. 2001.... 
Depot-specific regulation of glucose uptake and insulin sensitivity in HIV-lipodystrophyC Hadigan
Program in Nutritional Metabolism, Massachusetts General Hospital, 55 Fruit St, LON 207, Boston, MA 02114, USA
Am J Physiol Endocrinol Metab 290:E289-98. 2006....