Jan Grimm

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. ncbi request reprint Influence of thrombus age on the mechanical thrombectomy efficacy of the amplatz thrombectomy device in vitro
    Jan Grimm
    Klinik für Diagnostische Radiologie, Christian Albrechts Universitat zu Kiel, A Heller Strasse 9, 24105 Kiel, Germany
    Cardiovasc Intervent Radiol 26:265-8. 2003
  2. ncbi request reprint Hemolytic effect of deformed intra-arterial stents and stent grafts in vitro
    Jan Grimm
    Klinik für Diagnostische Radiologie der Christian Albrecht Universität CAU zu Kiel, A Heller Strasse 9, 24105 Kiel, Germany
    Eur Radiol 13:1333-8. 2003
  3. ncbi request reprint Comparison of various cerebral protection devices used for carotid artery stent placement: an in vitro experiment
    Stefan Muller-Hulsbeck
    Department of Radiology, University Hospital, Arnold Heller Strasse 9, 24105 Kiel, Germany
    J Vasc Interv Radiol 14:613-20. 2003
  4. ncbi request reprint Endovascular placement of self-expanding nitinol coil stents for the treatment of femoropopliteal obstructive disease
    Thomas Jahnke
    Department of Diagnostic Radiology, University Hospital, Christian Albrechts Universitat Kiel, Arnold Heller Strasse 9, 24105 Kiel, Germany
    J Vasc Interv Radiol 13:257-66. 2002
  5. ncbi request reprint Comparison and modification of two cerebral protection devices used for carotid angioplasty: in vitro experiment
    Stefan Muller-Hulsbeck
    Department of Radiology, University Hospital, Arnold Heller Strasse 9, 24105 Kiel, Germany
    Radiology 225:289-94. 2002
  6. ncbi request reprint In vitro effectiveness of mechanical thrombectomy devices for large vessel diameter and low-pressure fluid dynamic applications
    Stefan Muller-Hulsbeck
    Department of Radiology, University Hospital, Arnold Heller Strasse 9, 24105 Kiel, Germany
    J Vasc Interv Radiol 13:831-9. 2002
  7. pmc In vivo imaging of T cell delivery to tumors after adoptive transfer therapy
    Mikael J Pittet
    Center for Systems Biology, Massachusetts General Hospital and Harvard Medical School, Simches Research Building, 185 Cambridge Street, Boston, MA 02114, USA
    Proc Natl Acad Sci U S A 104:12457-61. 2007
  8. ncbi request reprint Tracking the recruitment of diabetogenic CD8+ T-cells to the pancreas in real time
    Anna Moore
    MGH MIT HMS Athinoula A Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Building 149, 13th Street, Room 2301, Charlestown, MA 02129, USA
    Diabetes 53:1459-66. 2004
  9. ncbi request reprint Magnetic resonance imaging of the pancreas and pancreatic tumors in a mouse orthotopic model of human cancer
    Jan Grimm
    Center for Molecular Imaging Research, Department of Radiology, Massachusetts General Hospital Harvard Medical School, Boston, MA, USA
    Int J Cancer 106:806-11. 2003
  10. ncbi request reprint A spatially and temporally restricted mouse model of soft tissue sarcoma
    David G Kirsch
    Center for Cancer Research, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, Massachusetts 02139, USA
    Nat Med 13:992-7. 2007

Collaborators

Detail Information

Publications23

  1. ncbi request reprint Influence of thrombus age on the mechanical thrombectomy efficacy of the amplatz thrombectomy device in vitro
    Jan Grimm
    Klinik für Diagnostische Radiologie, Christian Albrechts Universitat zu Kiel, A Heller Strasse 9, 24105 Kiel, Germany
    Cardiovasc Intervent Radiol 26:265-8. 2003
    ..To determine the efficacy of thrombectomy for the Amplatz Thrombectomy Device (ATD) according to the age of the thrombus...
  2. ncbi request reprint Hemolytic effect of deformed intra-arterial stents and stent grafts in vitro
    Jan Grimm
    Klinik für Diagnostische Radiologie der Christian Albrecht Universität CAU zu Kiel, A Heller Strasse 9, 24105 Kiel, Germany
    Eur Radiol 13:1333-8. 2003
    ..The stent grafts did not perform better than the stents. Differences in the design of a prosthesis and in the degree of stent deformation seem to have an influence on the hemolysis caused...
  3. ncbi request reprint Comparison of various cerebral protection devices used for carotid artery stent placement: an in vitro experiment
    Stefan Muller-Hulsbeck
    Department of Radiology, University Hospital, Arnold Heller Strasse 9, 24105 Kiel, Germany
    J Vasc Interv Radiol 14:613-20. 2003
    ..To compare the effectiveness of five basic cerebral protection devices designed for carotid angioplasty in an in-vitro bench-top model...
  4. ncbi request reprint Endovascular placement of self-expanding nitinol coil stents for the treatment of femoropopliteal obstructive disease
    Thomas Jahnke
    Department of Diagnostic Radiology, University Hospital, Christian Albrechts Universitat Kiel, Arnold Heller Strasse 9, 24105 Kiel, Germany
    J Vasc Interv Radiol 13:257-66. 2002
    ..To report on a prospective two-center study to evaluate safety and effectiveness of a self-expanding nitinol coil stent in patients with femoropopliteal obstructive disease...
  5. ncbi request reprint Comparison and modification of two cerebral protection devices used for carotid angioplasty: in vitro experiment
    Stefan Muller-Hulsbeck
    Department of Radiology, University Hospital, Arnold Heller Strasse 9, 24105 Kiel, Germany
    Radiology 225:289-94. 2002
    ..However, embolization into the external carotid artery was more frequent with use of the GuideWire, as compared with that with use of the Angioguard...
  6. ncbi request reprint In vitro effectiveness of mechanical thrombectomy devices for large vessel diameter and low-pressure fluid dynamic applications
    Stefan Muller-Hulsbeck
    Department of Radiology, University Hospital, Arnold Heller Strasse 9, 24105 Kiel, Germany
    J Vasc Interv Radiol 13:831-9. 2002
    ....
  7. pmc In vivo imaging of T cell delivery to tumors after adoptive transfer therapy
    Mikael J Pittet
    Center for Systems Biology, Massachusetts General Hospital and Harvard Medical School, Simches Research Building, 185 Cambridge Street, Boston, MA 02114, USA
    Proc Natl Acad Sci U S A 104:12457-61. 2007
    ....
  8. ncbi request reprint Tracking the recruitment of diabetogenic CD8+ T-cells to the pancreas in real time
    Anna Moore
    MGH MIT HMS Athinoula A Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Building 149, 13th Street, Room 2301, Charlestown, MA 02129, USA
    Diabetes 53:1459-66. 2004
    ..This study demonstrates the feasibility of visualizing the presence of ongoing autoimmune responses noninvasively...
  9. ncbi request reprint Magnetic resonance imaging of the pancreas and pancreatic tumors in a mouse orthotopic model of human cancer
    Jan Grimm
    Center for Molecular Imaging Research, Department of Radiology, Massachusetts General Hospital Harvard Medical School, Boston, MA, USA
    Int J Cancer 106:806-11. 2003
    ..MR serves as a noninvasive high-resolution image modality to monitor murine pancreas as well as size, growth and even areas of heterogeneity in orthotopic pancreatic tumors...
  10. ncbi request reprint A spatially and temporally restricted mouse model of soft tissue sarcoma
    David G Kirsch
    Center for Cancer Research, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, Massachusetts 02139, USA
    Nat Med 13:992-7. 2007
    ..Therefore, the intrinsic pathway of apoptosis seems sufficient to mediate p53 tumor suppression in an epithelial cancer, but not in this model of soft tissue sarcoma...
  11. ncbi request reprint Experience on endothelial cell adhesion on vascular stents and stent-grafts: first in vitro results
    Stefan Muller-Hulsbeck
    Department of Radiology, Hospital of Radiotherapy, Kiel, Germany
    Invest Radiol 37:314-20. 2002
    ..To evaluate endothelial cell (EC) attachment on different stents and stent-grafts combined with different coating materials...
  12. ncbi request reprint Restoration of p53 function leads to tumour regression in vivo
    Andrea Ventura
    Center for Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts 02142, USA
    Nature 445:661-5. 2007
    ..These results support efforts to treat human cancers by way of pharmacological reactivation of p53...
  13. ncbi request reprint Oligomerization of CXCL10 is necessary for endothelial cell presentation and in vivo activity
    Gabriele S V Campanella
    Division of Rheumatology, Allergy, and Immunology, Center for Immunology and Inflammatory Diseases, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA
    J Immunol 177:6991-8. 2006
    ..We therefore propose that oligomerization of IP-10 is required for presentation on endothelial cells and subsequent transendothelial migration, an essential step for lymphocyte recruitment in vivo...
  14. ncbi request reprint Deglycosylated anti-amyloid-beta antibodies eliminate cognitive deficits and reduce parenchymal amyloid with minimal vascular consequences in aged amyloid precursor protein transgenic mice
    Donna M Wilcock
    Department of Pharmacology and Molecular Therapeutics, University of South Florida, Tampa, Florida 33612, USA
    J Neurosci 26:5340-6. 2006
    ....
  15. ncbi request reprint Metabolic biotinylation of cell surface receptors for in vivo imaging
    Bakhos A Tannous
    Center for Molecular Imaging Research, Massachusetts General Hospital East, Building 149, 13th Street, Charlestown, Massachusetts 02129, USA
    Nat Methods 3:391-6. 2006
    ..This BAP-TM allows noninvasive real-time imaging of any cell type transduced to express this reporter protein in culture or in vivo...
  16. pmc Volumetric tomography of fluorescent proteins through small animals in vivo
    Giannis Zacharakis
    Laboratory for Bio optics and Molecular Imaging, Center for Molecular Imaging Research, Harvard Medical School, Charlestown, MA 02129, USA
    Proc Natl Acad Sci U S A 102:18252-7. 2005
    ..This technology can significantly improve imaging capacity over the current state of the art and should find wide in vivo imaging applications in drug discovery, immunology, and cancer research...
  17. ncbi request reprint Tomographic fluorescence mapping of tumor targets
    Xavier Montet
    Center for Molecular Imaging Research, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA
    Cancer Res 65:6330-6. 2005
    ..FMT measurements can be done serially, with short imaging times and within the same live animal. The described method should be valuable for rapidly profiling biological phenomena in vivo...
  18. pmc The neuronal scaffold protein Shank3 mediates signaling and biological function of the receptor tyrosine kinase Ret in epithelial cells
    Gunnar Schuetz
    MaxDelbrück Center for Molecular Medicine, Berlin, Germany
    J Cell Biol 167:945-52. 2004
    ..These results demonstrate that the Shank3 adaptor protein can mediate cellular signaling, and provide a molecular mechanism for the biological divergence between the Ret9 and Ret51 isoform...
  19. ncbi request reprint Profiling of microdissected gastric epithelial cells reveals a cell type-specific response to Helicobacter pylori infection
    Anne Mueller
    Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, CA 94305, USA
    Gastroenterology 127:1446-62. 2004
    ..We have explored the transcriptional response of the epithelium globally by applying a whole-genome approach to a murine model of infection...
  20. ncbi request reprint In vitro comparison of four cerebral protection filters for preventing human plaque embolization during carotid interventions
    Stefan Muller-Hulsbeck
    Department of Radiology, University Hospital, Kiel, Germany
    J Endovasc Ther 9:793-802. 2002
    ..To evaluate in an in vitro bench-top model the efficacy of 4 filtration devices designed for cerebral protection during carotid angioplasty...
  21. ncbi request reprint Novel nanosensors for rapid analysis of telomerase activity
    Jan Grimm
    Center for Molecular Imaging Research, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA
    Cancer Res 64:639-43. 2004
    ..Together, these studies establish and validate a novel and powerful tool for rapidly sensing telomerase activity and provide the rationale for developing analogous magnetic nanoparticles for in vivo sensing...
  22. pmc Distinct gene expression profiles characterize the histopathological stages of disease in Helicobacter-induced mucosa-associated lymphoid tissue lymphoma
    Anne Mueller
    Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, CA 94305 5402, USA
    Proc Natl Acad Sci U S A 100:1292-7. 2003
    ..Finally, we found that the transition to destructive lymphoepithelial lesions and malignant lymphoma is marked by an increase in transcription of a single gene encoding calgranulin AMrp-8...
  23. pmc Noninvasive in vivo imaging of monocyte trafficking to atherosclerotic lesions
    Moritz F Kircher
    Center for Molecular Imaging Research, Massachusetts General Hospital and Harvard Medical School, Charlestown, Mass, USA
    Circulation 117:388-95. 2008
    ..We sought to establish a noninvasive technique to determine monocyte trafficking to atherosclerotic lesions in live animals...