Research Topics
Species | Jeremy GreenSummaryAffiliation: Harvard University Country: USA Publications
Research Grants
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Detail Information
Publications
Anteroposterior neural tissue specification by activin-induced mesodermJ B Green
Division of Molecular Genetics, Dana Farber Cancer Institute, and Department of Genetics, Harvard Medical School, Boston, MA 02115, USA
Proc Natl Acad Sci U S A 94:8596-601. 1997..We discuss the implications of these results for patterning signals and the relationship between anteroposterior and dorsoventral axes...
Self-organization of vertebrate mesoderm based on simple boundary conditionsJeremy B A Green
Department of Cancer Biology, Dana Farber Cancer Institute and Department of Genetics, Harvard Medical School, Boston, MA 02115, USA
Dev Dyn 231:576-81. 2004..This process provides a remarkably simple organizing principle that contributes to the reliability of embryonic development as a whole...
Lkb1 and GSK3-beta: kinases at the center and poles of the actionJeremy B A Green
Dana Farber Cancer Institute and Department of Genetics, Harvard Medical School, 44 Binney St, Boston, Massachusetts 02115, USA
Cell Cycle 3:12-4. 2004
Morphogen gradients, positional information, and Xenopus: interplay of theory and experimentJeremy Green
Dana Farber Cancer Institute, Harvard Medical School Department of Genetics, Boston, Massachusetts 02115, USA
Dev Dyn 225:392-408. 2002..The physical mechanisms of morphogen gradient establishment are the focus of new interest at both the experimental and theoretical level. General themes and emerging trends in morphogen gradient studies are discussed...
Tales of tails: Brachyury and the T-box genesA I Kavka
Dana-Farber Cancer Institute, Boston, MA 02215, USA
Biochim Biophys Acta 1333:F73-84. 1997
Evidence for dual mechanisms of mesoderm establishment in Xenopus embryosA I Kavka
Department of Cancer Biology, Dana Farber Cancer Institute and Department of Genetics, Harvard Medical School, Boston, Massachusetts 02115, USA
Dev Dyn 219:77-83. 2000..These results are consistent with a dual mechanism of mesoderm establishment in which both VegT-initiated inductive signals and an intracellular VegT morphogen gradient play a part...
Molecular cloning and developmental expression of Par-1/MARK homologues XPar-1A and XPar-1B from Xenopus laevisOlga Ossipova
Department of Cancer Biology, Dana Farber Cancer Institute, Harvard Medical School, Boston, MA 02115, USA
Gene Expr Patterns 2:145-50. 2002....
Functional communication between endogenous BRCA1 and its partner, BARD1, during Xenopus laevis developmentV Joukov
Dana Farber Cancer Institute and Harvard Medical School, 44 Binney Street, Boston, MA 02115, USA
Proc Natl Acad Sci U S A 98:12078-83. 2001..The interdependent nature of BRCA1 and BARD1 function supports the view that BARD1/BRCA1 heterodimers play a major role in breast and ovarian cancer suppression...
PAR1 specifies ciliated cells in vertebrate ectoderm downstream of aPKCOlga Ossipova
Department of Molecular, Cell and Developmental Biology, Mount Sinai School of Medicine, Box 1020, New York, NY 10029, USA
Development 134:4297-306. 2007..The observed patterning mechanism may operate in a wide range of epithelial tissues in many species...
Distinct PAR-1 proteins function in different branches of Wnt signaling during vertebrate developmentOlga Ossipova
Department of Cancer Biology, Dana Farber Cancer Institute, Department of Genetics, Harvard Medical School, Boston, Massachusetts 02115, USA
Dev Cell 8:829-41. 2005..We conclude that PAR-1BY is required in the PCP branch and mediates Dsh membrane localization while PAR-1A and PAR-1BX are essential for canonical signaling to beta-catenin, possibly via targets other than Dishevelled...
Sophistications of cell sortingJeremy B A Green
Department of Craniofacial Development, King s College, London, SE1 9RT, UK
Nat Cell Biol 10:375-7. 2008..Direct force measurements reveal the role of cell-cortical tension, whereas epithelial-wrapping dominates the sorting of enclosed mesenchymal cells...
LKB1 (XEEK1) regulates Wnt signalling in vertebrate developmentOlga Ossipova
Department of Cancer Biology, Dana Farber Cancer Institute, Harvard Medical School, Boston, MA 02115, USA
Nat Cell Biol 5:889-94. 2003..These studies show that LKB1/XEEK1 is required for Wnt-beta-catenin signalling in frogs and mammals and provides novel insights into its role in vertebrate developmental patterning and carcinogenesis...
Convergent extension and the hexahedral cellJeremy B A Green
Department of Craniofacial Development, King s College London, Guys Tower Floor 27, London SE1 9RT, UK
Nat Cell Biol 9:1010-5. 2007....
Association of valproate-induced teratogenesis with histone deacetylase inhibition in vivoNadia Gurvich
Department of Cancer Biology, Harvard Medical School, Boston, Massachusetts, USA
FASEB J 19:1166-8. 2005..Together, the results demonstrate that the teratogenic effects of VPA are very likely mediated specifically by inhibition of HDACs...
Research Grants
- PATTERNING BY TGF BETA IN EARLY XENOPUS EMBRYOSJeremy Green; Fiscal Year: 2002..He also proposes to determine the effects on different processes in Xenopus development when different TGF-SM pathways are activated or blocked. ..
- Toxicant Target Genes in Xenopus and Zebrafish EmbryosJeremy Green; Fiscal Year: 2004..These experiments will generate useful comparative information as well as lay the foundation for illuminating the mechanisms of developmental toxicity at the molecular and genomic levels. ..
