Evangelos Gragoudas

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. ncbi request reprint Uveal melanoma: proton beam irradiation
    Evangelos S Gragoudas
    Department of Ophthalmology, Harvard Medical School, and Retina Service, Massachusetts Eye and Ear Infirmary, 243 Charles Street, Boston, MA 02114, USA
    Ophthalmol Clin North Am 18:111-8, ix. 2005
  2. ncbi request reprint Pegaptanib for neovascular age-related macular degeneration
    Evangelos S Gragoudas
    Retina Service, Massachusetts Eye and Ear Infirmary and Harvard Medical School, 243 Charles St, Boston, MA 02114, USA
    N Engl J Med 351:2805-16. 2004
  3. ncbi request reprint Proton beam irradiation of uveal melanomas: the first 30 years. The Weisenfeld Lecture
    Evangelos S Gragoudas
    Department of Ophthalmology, Retina Service, Massachusetts Eye and Ear Infirmary, Harvard Medical School, 243 Charles Street, Boston, MA 02114, USA
    Invest Ophthalmol Vis Sci 47:4666-73. 2006
  4. ncbi request reprint Evidence-based estimates of outcome in patients irradiated for intraocular melanoma
    Evangelos Gragoudas
    Retina Service, Massachusetts Eye and Ear Infirmary, 243 Charles St, Boston, MA 02114, USA
    Arch Ophthalmol 120:1665-71. 2002
  5. ncbi request reprint Safety and efficacy of intravitreal injection of ranibizumab in combination with verteporfin PDT on experimental choroidal neovascularization in the monkey
    Deeba Husain
    Angiogenesis and Laser Laboratory, Retina Service, Massachusetts Eye and Ear Infirmary, Boston, MA 02114, USA
    Arch Ophthalmol 123:509-16. 2005
  6. ncbi request reprint An antisense oligodeoxynucleotide against vascular endothelial growth factor in a nonhuman primate model of iris neovascularization
    Robert B Bhisitkul
    Department of Ophthalmology, Beckman Vision Center, University of California San Francisco, 94143, USA
    Arch Ophthalmol 123:214-9. 2005
  7. ncbi request reprint Selective photodynamic therapy by targeted verteporfin delivery to experimental choroidal neovascularization mediated by a homing peptide to vascular endothelial growth factor receptor-2
    Reem Z Renno
    Angiogenesis and Laser Laboratory, Retina Service, Massachusetts Eye and Ear Infirmary, Department of Ophthalmology, Harvard Medical School, Boston 02114, USA
    Arch Ophthalmol 122:1002-11. 2004
  8. pmc VEGF164-mediated inflammation is required for pathological, but not physiological, ischemia-induced retinal neovascularization
    Susumu Ishida
    Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Boston 02114, USA
    J Exp Med 198:483-9. 2003
  9. ncbi request reprint Reduced photoreceptor damage after photodynamic therapy through blockade of nitric oxide synthase in a model of choroidal neovascularization
    Haicheng She
    Angiogenesis and Laser Laboratories, Massachusetts Eye and Ear Infirmary, Department of Ophthalmology, Harvard Medical School, Boston, Massachusetts 02114, USA
    Invest Ophthalmol Vis Sci 48:2268-77. 2007
  10. ncbi request reprint Verteporfin photodynamic therapy in the rat model of choroidal neovascularization: angiographic and histologic characterization
    David N Zacks
    Retina Service and Angiogenesis Laboratory, Massachusetts Eye and Ear Infirmary, Harvard Medical School, 243 Charles Street, Boston, MA 02114, USA
    Invest Ophthalmol Vis Sci 43:2384-91. 2002

Detail Information

Publications54

  1. ncbi request reprint Uveal melanoma: proton beam irradiation
    Evangelos S Gragoudas
    Department of Ophthalmology, Harvard Medical School, and Retina Service, Massachusetts Eye and Ear Infirmary, 243 Charles Street, Boston, MA 02114, USA
    Ophthalmol Clin North Am 18:111-8, ix. 2005
    ..Although this method does not alter survival, preservation of the globe and, in some instances, visual function, is achieved. This article presents the authors' and other investigators' experience with proton therapy...
  2. ncbi request reprint Pegaptanib for neovascular age-related macular degeneration
    Evangelos S Gragoudas
    Retina Service, Massachusetts Eye and Ear Infirmary and Harvard Medical School, 243 Charles St, Boston, MA 02114, USA
    N Engl J Med 351:2805-16. 2004
    ..Pegaptanib, an anti-vascular endothelial growth factor therapy, was evaluated in the treatment of neovascular age-related macular degeneration...
  3. ncbi request reprint Proton beam irradiation of uveal melanomas: the first 30 years. The Weisenfeld Lecture
    Evangelos S Gragoudas
    Department of Ophthalmology, Retina Service, Massachusetts Eye and Ear Infirmary, Harvard Medical School, 243 Charles Street, Boston, MA 02114, USA
    Invest Ophthalmol Vis Sci 47:4666-73. 2006
  4. ncbi request reprint Evidence-based estimates of outcome in patients irradiated for intraocular melanoma
    Evangelos Gragoudas
    Retina Service, Massachusetts Eye and Ear Infirmary, 243 Charles St, Boston, MA 02114, USA
    Arch Ophthalmol 120:1665-71. 2002
    ..Until radiation therapy gained wide acceptance in the 1980s, enucleation was the standard treatment for the tumor. Long-term results after proton beam irradiation are now available...
  5. ncbi request reprint Safety and efficacy of intravitreal injection of ranibizumab in combination with verteporfin PDT on experimental choroidal neovascularization in the monkey
    Deeba Husain
    Angiogenesis and Laser Laboratory, Retina Service, Massachusetts Eye and Ear Infirmary, Boston, MA 02114, USA
    Arch Ophthalmol 123:509-16. 2005
    ....
  6. ncbi request reprint An antisense oligodeoxynucleotide against vascular endothelial growth factor in a nonhuman primate model of iris neovascularization
    Robert B Bhisitkul
    Department of Ophthalmology, Beckman Vision Center, University of California San Francisco, 94143, USA
    Arch Ophthalmol 123:214-9. 2005
    ..To evaluate an antisense oligodeoxynucleotide (AS-ODN) targeted against vascular endothelial growth factor for its effects on ocular angiogenesis and its intraocular localization in a nonhuman primate model of iris neovascularization...
  7. ncbi request reprint Selective photodynamic therapy by targeted verteporfin delivery to experimental choroidal neovascularization mediated by a homing peptide to vascular endothelial growth factor receptor-2
    Reem Z Renno
    Angiogenesis and Laser Laboratory, Retina Service, Massachusetts Eye and Ear Infirmary, Department of Ophthalmology, Harvard Medical School, Boston 02114, USA
    Arch Ophthalmol 122:1002-11. 2004
    ..To evaluate the feasibility, efficacy, and selectivity of photodynamic therapy (PDT) using targeted delivery of verteporfin to choroidal neovascularization (CNV) in the rat laser-injury model of CNV...
  8. pmc VEGF164-mediated inflammation is required for pathological, but not physiological, ischemia-induced retinal neovascularization
    Susumu Ishida
    Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Boston 02114, USA
    J Exp Med 198:483-9. 2003
    ..These processes provide positive and negative angiogenic regulation, respectively. Together, new therapeutic approaches for selectively targeting pathological, but not physiological, retinal neovascularization are outlined...
  9. ncbi request reprint Reduced photoreceptor damage after photodynamic therapy through blockade of nitric oxide synthase in a model of choroidal neovascularization
    Haicheng She
    Angiogenesis and Laser Laboratories, Massachusetts Eye and Ear Infirmary, Department of Ophthalmology, Harvard Medical School, Boston, Massachusetts 02114, USA
    Invest Ophthalmol Vis Sci 48:2268-77. 2007
    ..To investigate the role of nitric oxide synthase (NOS) in photoreceptor degeneration associated with photodynamic therapy (PDT) in a laser-induced model of choroidal neovascularization (CNV)...
  10. ncbi request reprint Verteporfin photodynamic therapy in the rat model of choroidal neovascularization: angiographic and histologic characterization
    David N Zacks
    Retina Service and Angiogenesis Laboratory, Massachusetts Eye and Ear Infirmary, Harvard Medical School, 243 Charles Street, Boston, MA 02114, USA
    Invest Ophthalmol Vis Sci 43:2384-91. 2002
    ..To develop a model of verteporfin photodynamic therapy (PDT) for experimental choroidal neovascularization CNV in the rat...
  11. doi request reprint Photoreceptor protection after photodynamic therapy using dexamethasone in a rat model of choroidal neovascularization
    Haicheng She
    Department of Ophthalmology, Angiogenesis and Laser Laboratories, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston 02114, Massachusetts, USA
    Invest Ophthalmol Vis Sci 49:5008-14. 2008
    ..To study whether corticosteroids protect photoreceptors when combined with photodynamic therapy (PDT) in a laser-induced model of choroidal neovascularization (CNV)...
  12. pmc Long-term risk of local failure after proton therapy for choroidal/ciliary body melanoma
    Evangelos S Gragoudas
    Clinical Research Unit, Retina Service, Massachusetts Eye and Ear Infirmary, Boston, USA
    Trans Am Ophthalmol Soc 100:43-8; discussion 48-9. 2002
    ..To quantitate long-term risk of local treatment failure after proton irradiation of choroidal/ciliary body melanomas and to evaluate risk of metastasis-related deaths after local failure...
  13. ncbi request reprint Photodynamic therapy induces caspase-dependent apoptosis in rat CNV model
    Akihisa Matsubara
    Angiogenesis and Laser Laboratories, Retina Service, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts, USA
    Invest Ophthalmol Vis Sci 48:4741-7. 2007
    ..To investigate the mechanism of cell death in laser-induced choroidal neovascularization (CNV) after photodynamic therapy (PDT)...
  14. ncbi request reprint Prevention of experimental choroidal neovascularization with intravitreal anti-vascular endothelial growth factor antibody fragment
    Magdalena G Krzystolik
    Retina Service, Massachusetts Eye and Ear Infirmary, 243 Charles St, Boston, MA 02114, USA
    Arch Ophthalmol 120:338-46. 2002
    ....
  15. doi request reprint Mortality after diagnosis of small melanocytic lesions of the choroid
    Anne Marie Lane
    Massachusetts Eye and Ear Infirmary, Boston, USA
    Arch Ophthalmol 128:996-1000. 2010
    ..To evaluate the risk of dying of metastatic choroidal melanoma in patients with small, indeterminate, pigmented lesions of the uveal tract...
  16. doi request reprint Survival in patients with presymptomatic diagnosis of metastatic uveal melanoma
    Ivana K Kim
    Retina Service, Massachusetts Eye and Ear Infirmary, 243 Charles Street, Boston, MA 02114, USA
    Arch Ophthalmol 128:871-5. 2010
    ..To determine if patients diagnosed as having metastatic uveal melanoma before the onset of symptoms experience more favorable survival outcomes than patients diagnosed after the onset of symptoms...
  17. doi request reprint Adjuvant interferon therapy for patients with uveal melanoma at high risk of metastasis
    Anne Marie Lane
    Retina Service, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts 02114, USA
    Ophthalmology 116:2206-12. 2009
    ..To examine whether interferon (IFN)-alfa-2a treatment after radiation or enucleation reduces death rates in patients with uveal melanoma...
  18. ncbi request reprint Effect of intravitreal injection of ranibizumab in combination with verteporfin PDT on normal primate retina and choroid
    Ivana K Kim
    Angiogenesis and Laser Laboratory, Retina Research Institute, Department of Ophthalmology, Harvard Medical School, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts 02114, USA
    Invest Ophthalmol Vis Sci 47:357-63. 2006
    ..San Francisco, CA) directed against vascular endothelial growth factor (VEGF) in combination with verteporfin photodynamic therapy (PDT) on normal primate retina and choroid...
  19. ncbi request reprint Melanocytoma of the optic nerve associated with sound-induced phosphenes
    Ivana K Kim
    Retina Service, Massachusetts Eye and Ear Infirmary, Boston 02114, USA
    Arch Ophthalmol 124:273-7. 2006
  20. ncbi request reprint Tumor basal area and metastatic death after proton beam irradiation for choroidal melanoma
    Wenjun Li
    Retina Service, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, USA
    Arch Ophthalmol 121:68-72. 2003
    ..Tumor dimension is an established prognostic factor for metastasis-related death after radiotherapy for uveal melanoma...
  21. ncbi request reprint Dose-dependent effect of pitavastatin on VEGF and angiogenesis in a mouse model of choroidal neovascularization
    Hadi J Zambarakji
    Angiogenesis Laboratory, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston 02114, USA
    Invest Ophthalmol Vis Sci 47:2623-31. 2006
    ..To evaluate the relation between statin therapy, vascular endothelial growth factor (VEGF) expression, vascular leakage, and CNV size in experimentally induced choroidal neovascularization (CNV)...
  22. doi request reprint Natural history of radiation papillopathy after proton beam irradiation of parapapillary melanoma
    Ivana K Kim
    Retina Service, Massachusetts Eye and Ear Infirmary, Department of Ophthalmology, Harvard Medical School, Boston, Massachusetts 02114, USA
    Ophthalmology 117:1617-22. 2010
    ..To evaluate the natural history of radiation papillopathy after proton beam irradiation of parapapillary choroidal melanoma...
  23. ncbi request reprint Histologic correlation of in vivo optical coherence tomography images of the human retina
    Teresa C Chen
    Harvard Medical School, Massachusetts Eye and Ear Infirmary, Boston, 02114, USA
    Am J Ophthalmol 141:1165-8. 2006
    ..To correlate in vivo human retina optical coherence tomography (OCT)3 images with histology...
  24. ncbi request reprint Investigating the effect of ciliary body photodynamic therapy in a glaucoma mouse model
    Akihisa Matsubara
    Angiogenesis and Laser Laboratories, Retina Service, Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts 02114, USA
    Invest Ophthalmol Vis Sci 47:2498-507. 2006
    ..To investigate the morphologic and functional effects of verteporfin ciliary body photodynamic therapy (PDT) in a murine glaucoma model and normal mouse eyes...
  25. doi request reprint In vivo evaluation of laser-induced choroidal neovascularization using spectral-domain optical coherence tomography
    Andrea Giani
    Angiogenesis and Laser Laboratories, Retina Service, Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts 02114, USA
    Invest Ophthalmol Vis Sci 52:3880-7. 2011
    ..To describe the in vivo evolution of laser-induced choroidal neovascularization (CNV) in mice using spectral domain optical coherence tomography (SD-OCT)...
  26. doi request reprint Posterior uveal melanoma in young patients treated with proton beam therapy
    Demetrios Vavvas
    Retina Service, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts 02131, USA
    Retina 30:1267-71. 2010
    ..The purpose was to study the clinical profile and prognosis of young patients with uveal melanoma treated by proton beam irradiation...
  27. pmc Increased choroidal neovascularization following laser induction in mice lacking lysyl oxidase-like 1
    Hyeong Gon Yu
    Angiogenesis Laboratory and Laser Laboratory, Retina Research Institute, Harvard Medical School, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts 02114, USA
    Invest Ophthalmol Vis Sci 49:2599-605. 2008
    ..This study investigated the influence of defective elastic fiber maintenance in the development of laser-induced CNV...
  28. ncbi request reprint Conservation treatment of the eye: Conformal proton reirradiation for recurrent uveal melanoma
    Laura Marucci
    Department of Radiation Oncology, Massachusetts General Hospital, Boston, MA 02114, USA
    Int J Radiat Oncol Biol Phys 64:1018-22. 2006
    ..To evaluate the outcomes of a second course of proton beam radiation therapy (PBRT) in patients with recurrent uveal melanoma...
  29. ncbi request reprint Expression of leukocyte adhesion molecules in human subfoveal choroidal neovascular membranes treated with and without photodynamic therapy
    Deborah C Yeh
    Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts 02215, USA
    Invest Ophthalmol Vis Sci 45:2368-73. 2004
    ....
  30. doi request reprint Proton beam irradiation using a light-field technique for the treatment of choroidal hemangiomas
    R V Paul Chan
    Retina Service, New York Presbyterian Hospital, Weill Cornell Medical College, New York, NY, USA
    Ophthalmologica 224:209-16. 2010
    ..To describe the clinical outcomes of patients with circumscribed and diffuse choroidal hemangiomas treated by proton beam irradiation using a nonsurgical light-field technique...
  31. ncbi request reprint Expression of pigment epithelium-derived factor in experimental choroidal neovascularization
    Reem Z Renno
    Angiogenesis Laboratory, Retina Research Institute, Massachusetts Eye and Ear Infirmary, 245 Charles Street, Boston, MA 02114, USA
    Invest Ophthalmol Vis Sci 43:1574-80. 2002
    ..To investigate the expression of pigment epithelium-derived factor (PEDF) in the rat laser-injury model of choroidal neovascularization (CNV)...
  32. ncbi request reprint Proton beam irradiation for neovascular age-related macular degeneration
    Hadi J Zambarakji
    Retina Service, Massachusetts Eye and Ear Infirmary, Department of Ophthalmology, Harvard Medical School, Boston, Massachusetts 02114, USA
    Ophthalmology 113:2012-9. 2006
    ..To evaluate safety and visual outcomes after proton therapy for subfoveal neovascular age-related macular degeneration (AMD)...
  33. ncbi request reprint Endogenous endostatin inhibits choroidal neovascularization
    Alexander G Marneros
    Department of Developmental Biology, Harvard School of Dental Medicine, 188 Longwood Ave, Boston, MA 02115, USA
    FASEB J 21:3809-18. 2007
    ..Endostatin may have a regulatory role in the pathogenesis of CNV and could be used therapeutically to inhibit growth and leakage of CNV lesions...
  34. ncbi request reprint Targeted disruption of the CD18 or ICAM-1 gene inhibits choroidal neovascularization
    Eiji Sakurai
    Department of Ophthalmology, University of Kentucky, Lexington, Kentucky 40536 0284, USA
    Invest Ophthalmol Vis Sci 44:2743-9. 2003
    ..To investigate the role of the leukocyte adhesion molecules CD18 and intercellular adhesion molecule (ICAM)-1 in the development of choroidal neovascularization (CNV)...
  35. ncbi request reprint Identification of Chlamydia pneumoniae within human choroidal neovascular membranes secondary to age-related macular degeneration
    Murat V Kalayoglu
    Angiogenesis Laboratory, Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, MA 02114, USA
    Graefes Arch Clin Exp Ophthalmol 243:1080-90. 2005
    ..pneumoniae. These data indicate that a pathogen capable of inducing chronic inflammation and pro-angiogenic cytokines can be detected in some AMD CNV, and suggest that infection may contribute to the pathogenesis of AMD...
  36. ncbi request reprint Treatment of metastatic tumors of the choroid with proton beam irradiation
    Efthymia K Tsina
    Retina Service, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts 02114, USA
    Ophthalmology 112:337-43. 2005
    ..To describe the clinical outcomes of patients treated by proton beam irradiation for choroidal metastatic tumors...
  37. ncbi request reprint Localization of rose bengal, aluminum phthalocyanine tetrasulfonate, and chlorin e6 in the rabbit eye
    Robert Haimovici
    Laser Research Laboratory, Retina Service, Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts, USA
    Retina 22:65-74. 2002
    ..We investigated the intraocular localization of xanthene, phthalocyanine, and chlorin photosensitizers by using fluorescence microscopy and digital fundus fluorescence angiography...
  38. ncbi request reprint Photosensitizers in photodynamic therapy of choroidal neovascularization
    Rafael L Ufret-Vincenty
    Massachusetts Eye and Ear Infirmary, Harvard Medical School, 243 Charles Street, Boston, MA 02114, USA
    Int Ophthalmol Clin 44:63-80. 2004
  39. ncbi request reprint Inhibition of Hsp90 attenuates inflammation in endotoxin-induced uveitis
    Vassiliki Poulaki
    Angiogenesis Laser Laboratory, Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, 243 Charles St, Boston, MA 02114, USA
    FASEB J 21:2113-23. 2007
    ..17-AAG has demonstrated a favorable safety profile in clinical trials in cancer patients and represents a promising therapeutic agent for the treatment of inflammatory eye diseases...
  40. ncbi request reprint High-grade uveal B-cell lymphoma as the initial feature in Richter syndrome
    Jessica P Fernandez-Suntay
    Massachusetts Eye and Ear Infirmary, 243 Charles St, Boston, MA 02114, USA
    Arch Ophthalmol 120:1383-5. 2002
  41. pmc Vascular adhesion protein-1 blockade suppresses choroidal neovascularization
    Kousuke Noda
    Angiogenesis Laboratory, Massachusetts Eye and Ear Infirmary, Boston, MA 02114, USA
    FASEB J 22:2928-35. 2008
    ..Inhibition of VAP-1 may become a new therapeutic strategy in the treatment of AMD...
  42. ncbi request reprint The expanded clinical spectrum of deferoxamine retinopathy
    Robert Haimovici
    Department of Ophthalmology, Boston University School of Medicine, DOB 10 720 Harrison Avenue, Boston, MA 02118, USA
    Ophthalmology 109:164-71. 2002
    ..To describe early and unusual features in 16 patients with deferoxamine-induced retinal toxicity and to assess the role of diagnostic tests in the diagnosis and management of patients with the disorder...
  43. ncbi request reprint MRI of blood volume and cellular uptake of superparamagnetic iron in an animal model of choroidal melanoma
    Matthias Krause
    Massachusetts Eye and Ear Infirmary, Department of Ophthalmology, Harvard Medical School, Boston, Mass 02114, USA
    Ophthalmic Res 34:241-50. 2002
    ..Further study is necessary to determine the feasibility of this technique for the tumor diagnosis and evaluation of tumor viability following treatments...
  44. doi request reprint Role of alpha 4 integrin (CD49d) in the pathogenesis of diabetic retinopathy
    Eirini Iliaki
    Angiogenesis Laboratory, Massachusetts Eye and Ear Infirmary, Department of Ophthalmology, Harvard Medical School, Boston, Massachusetts 02114, USA
    Invest Ophthalmol Vis Sci 50:4898-904. 2009
    ..The authors have now studied the role of integrin alpha 4/CD49d in the pathogenesis of diabetic retinopathy...
  45. doi request reprint In vivo imaging of endothelial injury in choriocapillaris during endotoxin-induced uveitis
    Shinsuke Miyahara
    Angiogenesis Laboratory, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, MA 02114 USA
    FASEB J 22:1973-80. 2008
    ..This technique may help to diagnose subclinical signs of ocular inflammatory diseases...
  46. doi request reprint Characterization of azurocidin as a permeability factor in the retina: involvement in VEGF-induced and early diabetic blood-retinal barrier breakdown
    Dimitra Skondra
    Angiogenesis Laboratory, Massachusetts Eye and Ear Infirmary, Department of Ophthalmology, Harvard Medical School, Boston, MA 02114, USA
    Invest Ophthalmol Vis Sci 49:726-31. 2008
    ..Azurocidin, released by neutrophils during leukocyte-endothelial interaction, is a main cause of neutrophil-evoked vascular leakage. Its role in the retina, however, is unknown...
  47. ncbi request reprint Controlled delivery of the anti-VEGF aptamer EYE001 with poly(lactic-co-glycolic)acid microspheres
    Karen G Carrasquillo
    Angiogenesis and Retina Research Laboratory, Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, 325 Cambridge Street, Boston, MA 02114, USA
    Invest Ophthalmol Vis Sci 44:290-9. 2003
    ..To develop a controlled-drug delivery system for the long-term inhibition of vascular endothelial growth factor (VEGF) and its mediated responses...
  48. ncbi request reprint Inhibition of vascular adhesion protein-1 suppresses endotoxin-induced uveitis
    Kousuke Noda
    Department of Ophthalmology, Massachusetts Eye and Ear Infirmary and Harvard Medical School, Boston, Massachusetts, USA
    FASEB J 22:1094-103. 2008
    ..VAP-1 inhibition may become a novel strategy in the treatment of ocular inflammatory diseases...
  49. ncbi request reprint Treatment of experimental choroidal melanoma with an Nd:yttrium-lanthanum-fluoride laser at 1047 nm
    Matthias H J Krause
    Retina Service, Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, 243 Charles St, Boston, MA 02114, USA
    Arch Ophthalmol 121:357-63. 2003
    ..To evaluate the effect of a new infrared laser in the destruction of pigmented choroidal melanomas...
  50. ncbi request reprint MRI of blood volume with superparamagnetic iron in choroidal melanoma treated with thermotherapy
    Matthias H J Krause
    Massachusetts General Hospital Nuclear Magnetic Resonance MGH NMR Center, Harvard Medical School, Charlestown, MA, USA
    Magn Reson Imaging 22:779-87. 2004
    ..Further study is necessary to determine whether MRI can localize areas of tumor regrowth within tumors treated incompletely...
  51. ncbi request reprint MRI of blood volume with MS 325 in experimental choroidal melanoma
    Matthias H J Krause
    Massachusetts Eye and Ear Infirmary, Department of Ophthalmology, Harvard Medical School, Boston, MA 02114, USA
    Magn Reson Imaging 21:725-32. 2003
    ..Further studies are needed to investigate whether this technique allows the evaluation of tumor viability following treatments...
  52. ncbi request reprint Verteporfin therapy of subfoveal choroidal neovascularization in age-related macular degeneration: meta-analysis of 2-year safety results in three randomized clinical trials: Treatment Of Age-Related Macular Degeneration With Photodynamic Therapy and Vert
    Mohammad Azab
    Retina 24:1-12. 2004
    ....
  53. ncbi request reprint Verteporfin therapy of subfoveal choroidal neovascularization in patients with age-related macular degeneration: additional information regarding baseline lesion composition's impact on vision outcomes-TAP report No. 3
    Neil M Bressler
    Wilmer Photograph Reading Center, The Johns Hopkins University School of Medicine, Baltimore, MD 21205 2002, USA
    Arch Ophthalmol 120:1443-54. 2002
    ....
  54. ncbi request reprint [Photodynamic therapy of pigmented choroidal melanomas in rabbits]
    Likuan Hu
    Tumor Center of Qilu Hospital, Shandong University, Jinan 250012, China
    Zhonghua Yan Ke Za Zhi 38:491-4. 2002
    ..To evaluate the effect of photo-dynamic therapy in the destruction of experimental pigmented choroidal melanoma using a liposomal preparation of benzoporphyrin derivative (BPD), verteporfin...