Chiara Gerhardinger

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. ncbi Expression of acute-phase response proteins in retinal Müller cells in diabetes
    Chiara Gerhardinger
    Schepens Eye Research Institute, Harvard Medical School, Boston, MA 02114, USA
    Invest Ophthalmol Vis Sci 46:349-57. 2005
  2. pmc The transforming growth factor-beta pathway is a common target of drugs that prevent experimental diabetic retinopathy
    Chiara Gerhardinger
    Schepens Eye Research Institute and Department of Ophthalmology, Harvard Medical School, Boston, MA, USA
    Diabetes 58:1659-67. 2009
  3. ncbi A selective aldose reductase inhibitor of a new structural class prevents or reverses early retinal abnormalities in experimental diabetic retinopathy
    Wei Sun
    Schepens Eye Research Institute, Harvard Medical School, 20 Staniford St, Boston, MA 02114, USA
    Diabetes 55:2757-62. 2006
  4. ncbi Studies of rat and human retinas predict a role for the polyol pathway in human diabetic retinopathy
    Zeina Dagher
    Harvard Medical School, Schepens Eye Research Institute, 20 Staniford St, Boston, MA 02114, USA
    Diabetes 53:2404-11. 2004
  5. ncbi Aspirin at low-intermediate concentrations protects retinal vessels in experimental diabetic retinopathy through non-platelet-mediated effects
    Wei Sun
    Schepens Eye Research Institute and Department of Ophthalmology, Harvard Medical School, 20 Staniford St, Boston, Massachusetts 02114, USA
    Diabetes 54:3418-26. 2005
  6. pmc IL-1β is upregulated in the diabetic retina and retinal vessels: cell-specific effect of high glucose and IL-1β autostimulation
    Yang Liu
    Schepens Eye Research Institute and the Department of Ophthalmology, Harvard Medical School, Boston, Massachusetts, United States of America
    PLoS ONE 7:e36949. 2012
  7. ncbi A role for the polyol pathway in the early neuroretinal apoptosis and glial changes induced by diabetes in the rat
    Veronica Asnaghi
    Schepens Eye Research Institute and Department of Ophthalmology, Harvard Medical School, Boston, Massachusetts 02114, USA
    Diabetes 52:506-11. 2003
  8. ncbi Early complement activation and decreased levels of glycosylphosphatidylinositol-anchored complement inhibitors in human and experimental diabetic retinopathy
    Jing Zhang
    Schepens Eye Research Institute, Harvard Medical School, 20 Staniford Street, Boston, MA 02114, USA
    Diabetes 51:3499-504. 2002

Collaborators

Detail Information

Publications8

  1. ncbi Expression of acute-phase response proteins in retinal Müller cells in diabetes
    Chiara Gerhardinger
    Schepens Eye Research Institute, Harvard Medical School, Boston, MA 02114, USA
    Invest Ophthalmol Vis Sci 46:349-57. 2005
    ..To characterize the whole spectrum of gene expression changes induced by diabetes in retinal Müller glial cells...
  2. pmc The transforming growth factor-beta pathway is a common target of drugs that prevent experimental diabetic retinopathy
    Chiara Gerhardinger
    Schepens Eye Research Institute and Department of Ophthalmology, Harvard Medical School, Boston, MA, USA
    Diabetes 58:1659-67. 2009
    ..We aimed to identify candidate drug targets by investigating the molecular effects of drugs that prevent retinal capillary demise in the diabetic rat...
  3. ncbi A selective aldose reductase inhibitor of a new structural class prevents or reverses early retinal abnormalities in experimental diabetic retinopathy
    Wei Sun
    Schepens Eye Research Institute, Harvard Medical School, 20 Staniford St, Boston, MA 02114, USA
    Diabetes 55:2757-62. 2006
    ....
  4. ncbi Studies of rat and human retinas predict a role for the polyol pathway in human diabetic retinopathy
    Zeina Dagher
    Harvard Medical School, Schepens Eye Research Institute, 20 Staniford St, Boston, MA 02114, USA
    Diabetes 53:2404-11. 2004
    ..Excess aldose reductase activity can be a mechanism for human diabetic retinopathy...
  5. ncbi Aspirin at low-intermediate concentrations protects retinal vessels in experimental diabetic retinopathy through non-platelet-mediated effects
    Wei Sun
    Schepens Eye Research Institute and Department of Ophthalmology, Harvard Medical School, 20 Staniford St, Boston, Massachusetts 02114, USA
    Diabetes 54:3418-26. 2005
    ..Aspirin at low-intermediate concentrations selectively prevented microangiopathy. The minimal effective dose of aspirin should now be sought...
  6. pmc IL-1β is upregulated in the diabetic retina and retinal vessels: cell-specific effect of high glucose and IL-1β autostimulation
    Yang Liu
    Schepens Eye Research Institute and the Department of Ophthalmology, Harvard Medical School, Boston, Massachusetts, United States of America
    PLoS ONE 7:e36949. 2012
    ..Interrupting the vicious circle triggered by IL-1β autostimulation could limit the progression of diabetic retinopathy...
  7. ncbi A role for the polyol pathway in the early neuroretinal apoptosis and glial changes induced by diabetes in the rat
    Veronica Asnaghi
    Schepens Eye Research Institute and Department of Ophthalmology, Harvard Medical School, Boston, Massachusetts 02114, USA
    Diabetes 52:506-11. 2003
    ..These findings have implications for how to evaluate the role of the polyol pathway in diabetic retinopathy...
  8. ncbi Early complement activation and decreased levels of glycosylphosphatidylinositol-anchored complement inhibitors in human and experimental diabetic retinopathy
    Jing Zhang
    Schepens Eye Research Institute, Harvard Medical School, 20 Staniford Street, Boston, MA 02114, USA
    Diabetes 51:3499-504. 2002
    ..These are novel clues for probing how diabetes affects and damages vascular cells...