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Genomes and GenesSpecies | Margaret A GatesSummaryAffiliation: Harvard University Country: USA Publications
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Publications
ABO blood group and breast cancer incidence and survivalMargaret A Gates
Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA, USA
Int J Cancer 130:2129-37. 2012..35-3.86) for B/B, compared to O/O. No significant association was noted between blood type and overall or breast cancer-specific mortality. Our results suggest no association between ABO blood group and breast cancer risk or survival...
Risk factors for epithelial ovarian cancer by histologic subtypeMargaret A Gates
Channing Laboratory, 181 Longwood Avenue, Boston, MA 02115, USA
Am J Epidemiol 171:45-53. 2010..03). Results suggest that associations with several ovarian cancer risk factors vary by subtype, and these differences are consistent with known similarities between each major histologic subtype and its normal tissue counterpart...
Analgesic use and sex steroid hormone concentrations in postmenopausal womenMargaret A Gates
Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
Cancer Epidemiol Biomarkers Prev 19:1033-41. 2010..04). Among postmenopausal women, regular users of aspirin and other analgesics may have lower estrogen levels than nonusers, which could contribute to a decreased risk of breast or ovarian cancer among analgesic users...
ABO blood group and incidence of epithelial ovarian cancerMargaret A Gates
Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA, USA
Int J Cancer 128:482-6. 2011..Additional studies are needed to confirm this association and to explore the mechanisms through which blood group may influence ovarian cancer risk...
Talc use, variants of the GSTM1, GSTT1, and NAT2 genes, and risk of epithelial ovarian cancerMargaret A Gates
Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
Cancer Epidemiol Biomarkers Prev 17:2436-44. 2008..These results suggest that women with certain genetic variants may have a higher risk of ovarian cancer associated with genital talc use. Additional research is needed on these interactions and the underlying biological mechanisms...
Breast cancer susceptibility alleles and ovarian cancer risk in 2 study populationsMargaret A Gates
Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
Int J Cancer 124:729-33. 2009..16-1.18 per allele at the alpha=0.05 level in the pooled analysis. Our results do not provide strong support for an association between these breast cancer susceptibility alleles and epithelial ovarian cancer risk...
Flavonoid intake and ovarian cancer risk in a population-based case-control studyMargaret A Gates
Department of Medicine, Channing Laboratory, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
Int J Cancer 124:1918-25. 2009..However, given the findings of previous studies and the biologic plausibility of this association, additional studies are warranted...
Common genetic variation in IGF1, IGFBP1 and IGFBP3 and ovarian cancer riskKathryn L Terry
Obstetrics and Gynecology Epidemiology Center, Department of Obstetrics and Gynecology, Brigham and Women s Hospital, Boston, MA 02115, USA
Carcinogenesis 30:2042-6. 2009..Of particular interest was the IGFBP3 SNP rs2270628, which was associated with both increased IGF1 plasma levels and higher ovarian cancer risk...
Risk factors for ductal and lobular breast cancer: results from the nurses' health studyJoanne Kotsopoulos
Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
Breast Cancer Res 12:R106. 2010....
MTHFR polymorphisms in relation to ovarian cancer riskKathryn L Terry
Ob Gyn Epidemiology Center, Brigham and Women s Hospital, Boston, MA 02115, USA
Gynecol Oncol 119:319-24. 2010..Thus, we examined ovarian cancer risk in relation to two functional polymorphisms (C677T and A1298C) in the MTHFR gene...
A prospective study of dietary flavonoid intake and incidence of epithelial ovarian cancerMargaret A Gates
Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA
Int J Cancer 121:2225-32. 2007..If confirmed, these results would provide an important target for ovarian cancer prevention...
Polymorphisms in the vitamin D receptor and risk of ovarian cancer in four studiesShelley S Tworoger
Channing Laboratory, Boston, MA 02115, USA
Cancer Res 69:1885-91. 2009..34-1.28), and among women with the Ff or ff genotype the OR was 0.71 (95% CI, 0.43-1.18). Our results of an association with the Fok1 VDR polymorphism further support a role of the vitamin D pathway in ovarian carcinogenesis...
Caffeine, alcohol, smoking, and the risk of incident epithelial ovarian cancerShelley S Tworoger
Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
Cancer 112:1169-77. 2008..Therefore, the associations between these exposures and ovarian cancer risk were prospectively examined among 110,454 women in the Nurses' Health Study (NHS) for the smoking analyses and 80,253 women for the dietary analyses...
Validation of tissue microarray technology in ovarian cancer: results from the Nurses' Health StudyJonathan L Hecht
Department of Pathology, Beth Israel Deaconess Medical Center, 330 Brookline Avenue, Boston, MA 02215, USA
Cancer Epidemiol Biomarkers Prev 17:3043-50. 2008..Tissue microarrays (TMAs) allow high-throughput evaluation of protein expression from archived tissue samples. We identified characteristics specific to ovarian cancer that may influence TMA interpretation...
Perineal use of talcum powder and endometrial cancer riskStalo Karageorgi
Department of Environmental Health, Harvard School of Public Health, and Department of Medicine, Brigham and Women s Hospital, 677 Huntington Avenue, Boston, MA 02115, USA
Cancer Epidemiol Biomarkers Prev 19:1269-75. 2010..However, the relationship between talcum powder use and other gynecologic malignancies such as endometrial cancer has not been examined, and little information is available on nonhormonal risk factors for endometrial cancer...
Genetic variation in TYMS in the one-carbon transfer pathway is associated with ovarian carcinoma types in the Ovarian Cancer Association ConsortiumLinda E Kelemen
Department of Population Health Research, Alberta Health Services Cancer Care, 1331 29th Street Northwest, Calgary, Alberta T2N4N2, Canada
Cancer Epidemiol Biomarkers Prev 19:1822-30. 2010....
Analgesic use in relation to sex hormone and prolactin concentrations in premenopausal womenScott R Bauer
Channing Division of Network Medicine, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, 181 Longwood Ave, 3rd Floor, Boston, MA, 02115, USA
Cancer Causes Control 24:1087-97. 2013..Common analgesics (aspirin, non-aspirin NSAIDs, and acetaminophen) may be associated with hormone-related cancers, possibly via effects on sex hormone and prolactin concentrations...
ABO blood group and risk of epithelial ovarian cancer within the Ovarian Cancer Association ConsortiumElizabeth M Poole
Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, 181 Longwood Ave, 3rd Floor, Boston, MA 02115, USA
Cancer Causes Control 23:1805-10. 2012..Previous studies have examined the association between ABO blood group and ovarian cancer risk, with inconclusive results...
Operating room nursing and lung cancer risk in a cohort of female registered nursesMargaret A Gates
Department of Medicine, Bridham and Women s Hospital and Harvard Medical School, Channing Laboratory, Third Floor, 181 Longwood Avenue, Boston, MA 02115, USA
Scand J Work Environ Health 33:140-7. 2007..We examined the association between duration of employment as an operating room nurse, a proxy measure for surgical smoke exposure, and subsequent lung cancer risk...
