Wendy S Garrett

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. ncbi Enterobacteriaceae act in concert with the gut microbiota to induce spontaneous and maternally transmitted colitis
    Wendy S Garrett
    Department of Immunology and Infectious Diseases, Harvard School of Public Health, Boston, MA 02115, USA
    Cell Host Microbe 8:292-300. 2010
  2. ncbi Homeostasis and inflammation in the intestine
    Wendy S Garrett
    Department of Immunology and Infectious Diseases, Harvard School of Public Health, Boston, MA 02115, USA
    Cell 140:859-70. 2010
  3. ncbi Colitis-associated colorectal cancer driven by T-bet deficiency in dendritic cells
    Wendy S Garrett
    Department of Immunology and Infectious Diseases, Harvard School of Public Health, Boston, MA 02115, USA
    Cancer Cell 16:208-19. 2009
  4. ncbi Bifidobacterium animalis subsp. lactis fermented milk product reduces inflammation by altering a niche for colitogenic microbes
    Patrick Veiga
    Harvard School of Public Health, Boston, MA 02115, USA
    Proc Natl Acad Sci U S A 107:18132-7. 2010
  5. ncbi T-bet-/- RAG2-/- ulcerative colitis: the role of T-bet as a peacekeeper of host-commensal relationships
    Wendy S Garrett
    Department of Immunology and Infectious Diseases, Harvard School of Public Health, Boston, MA 02115, USA
    Cytokine 48:144-7. 2009
  6. ncbi Severity of innate immune-mediated colitis is controlled by the cytokine deficiency-induced colitis susceptibility-1 (Cdcs1) locus
    Joerg Ermann
    Department of Immunology and Infectious Diseases, Harvard School of Public Health, Harvard Medical School, Boston, MA 02115, USA
    Proc Natl Acad Sci U S A 108:7137-41. 2011
  7. ncbi Current concepts of the intestinal microbiota and the pathogenesis of infection
    Leslie H Wardwell
    Department of Immunology and Infectious Diseases, Harvard School of Public Health, 665 Huntington Avenue, SPH 1 909, Boston, MA, 02115, USA
    Curr Infect Dis Rep 13:28-34. 2011
  8. ncbi Metagenomic biomarker discovery and explanation
    Nicola Segata
    Department of Biostatistics, 677 Huntington Avenue, Harvard School of Public Health, Boston, MA 02115, USA
    Genome Biol 12:R60. 2011
  9. ncbi Host and gut microbiota symbiotic factors: lessons from inflammatory bowel disease and successful symbionts
    Sonia A Ballal
    Harvard School of Public Health, Boston, MA, USA
    Cell Microbiol 13:508-17. 2011
  10. ncbi Communicable ulcerative colitis induced by T-bet deficiency in the innate immune system
    Wendy S Garrett
    Department of Immunology and Infectious Diseases, Harvard School of Public Health, Boston, MA 02115, USA
    Cell 131:33-45. 2007

Collaborators

Detail Information

Publications10

  1. ncbi Enterobacteriaceae act in concert with the gut microbiota to induce spontaneous and maternally transmitted colitis
    Wendy S Garrett
    Department of Immunology and Infectious Diseases, Harvard School of Public Health, Boston, MA 02115, USA
    Cell Host Microbe 8:292-300. 2010
    ..Cross-fostering experiments indicated a role for these organisms in maternal transmission of disease. Our findings illustrate how gut microbial communities work in concert with specific culturable colitogenic agents to cause IBD...
  2. ncbi Homeostasis and inflammation in the intestine
    Wendy S Garrett
    Department of Immunology and Infectious Diseases, Harvard School of Public Health, Boston, MA 02115, USA
    Cell 140:859-70. 2010
    ..In this Review, we consider the many cellular and molecular methods by which inflammatory responses are regulated to maintain intestinal homeostasis and the disease states that can ensue when this balance is lost...
  3. ncbi Colitis-associated colorectal cancer driven by T-bet deficiency in dendritic cells
    Wendy S Garrett
    Department of Immunology and Infectious Diseases, Harvard School of Public Health, Boston, MA 02115, USA
    Cancer Cell 16:208-19. 2009
    ..TRUC colitis-associated colorectal cancer resembles the human disease and provides ample opportunity to probe how inflammation drives colorectal cancer development and to test preventative and therapeutic strategies preclinically...
  4. ncbi Bifidobacterium animalis subsp. lactis fermented milk product reduces inflammation by altering a niche for colitogenic microbes
    Patrick Veiga
    Harvard School of Public Health, Boston, MA 02115, USA
    Proc Natl Acad Sci U S A 107:18132-7. 2010
    ..lactis-containing fermented milk product, and therefore this model provides a framework for evaluating and optimizing probiotic-based functional foods...
  5. ncbi T-bet-/- RAG2-/- ulcerative colitis: the role of T-bet as a peacekeeper of host-commensal relationships
    Wendy S Garrett
    Department of Immunology and Infectious Diseases, Harvard School of Public Health, Boston, MA 02115, USA
    Cytokine 48:144-7. 2009
    ..1]. The TRUC (T-bet-/- RAG2-/- ulcerative colitis) model is discussed in the broader context of the adaptive and innate immune mechanisms that regulate host-commensal relationships within the intestine...
  6. ncbi Severity of innate immune-mediated colitis is controlled by the cytokine deficiency-induced colitis susceptibility-1 (Cdcs1) locus
    Joerg Ermann
    Department of Immunology and Infectious Diseases, Harvard School of Public Health, Harvard Medical School, Boston, MA 02115, USA
    Proc Natl Acad Sci U S A 108:7137-41. 2011
    ..We conclude that the Cdcs1 locus controls colitis severity in T-bet(-/-).Rag2(-/-) mice through innate immune cells...
  7. ncbi Current concepts of the intestinal microbiota and the pathogenesis of infection
    Leslie H Wardwell
    Department of Immunology and Infectious Diseases, Harvard School of Public Health, 665 Huntington Avenue, SPH 1 909, Boston, MA, 02115, USA
    Curr Infect Dis Rep 13:28-34. 2011
    ..Key concepts of colonization resistance, host-commensal microbe interaction in immunity, antibiotics and gut bacterial communities, viral-gut bacterial interactions, and evolving methods for studying commensal microbes are explored...
  8. ncbi Metagenomic biomarker discovery and explanation
    Nicola Segata
    Department of Biostatistics, 677 Huntington Avenue, Harvard School of Public Health, Boston, MA 02115, USA
    Genome Biol 12:R60. 2011
    ..We extensively validate our method on several microbiomes and a convenient online interface for the method is provided at http://huttenhower.sph.harvard.edu/lefse/...
  9. ncbi Host and gut microbiota symbiotic factors: lessons from inflammatory bowel disease and successful symbionts
    Sonia A Ballal
    Harvard School of Public Health, Boston, MA, USA
    Cell Microbiol 13:508-17. 2011
    ..While model symbionts have provided perspective into host-microbial homeostasis, high-throughput approaches are becoming increasingly practical for functionally characterizing the gut microbiota as a community...
  10. ncbi Communicable ulcerative colitis induced by T-bet deficiency in the innate immune system
    Wendy S Garrett
    Department of Immunology and Infectious Diseases, Harvard School of Public Health, Boston, MA 02115, USA
    Cell 131:33-45. 2007
    ..These findings reveal a novel function for T-bet as a peacekeeper of host-commensal relationships and provide new perspectives on the pathophysiology of IBD...