A M Galaburda

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. ncbi request reprint [Developmental dyslexia]
    A M Galaburda
    Harvard Medical School, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
    Rev Neurol 36:S3-9. 2003
  2. ncbi request reprint [Williams syndrome. A summary of cognitive, electrophysiological, anatomofunctional, microanatomical and genetic findings]
    A M Galaburda
    Harvard Medical School, Beth Israel Deaconess Medical Center, Boston, MA 02115, USA
    Rev Neurol 36:S132-7. 2003
  3. ncbi request reprint Williams syndrome: neuronal size and neuronal-packing density in primary visual cortex
    Albert M Galaburda
    Beth Israel Deaconess Medical Center, 330 Brookline Ave, Boston, MA 02215, USA
    Arch Neurol 59:1461-7. 2002
  4. ncbi request reprint Developmental disorders of vision
    Albert M Galaburda
    Division of Behavioral Neurology, Harvard Medical School, Beth Israel Deaconess Medical Center, Boston, MA, USA
    Neurol Clin 21:687-707. 2003
  5. ncbi request reprint Dorsal forebrain anomaly in Williams syndrome
    A M Galaburda
    Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, 330 Brookline Ave, Boston, MA 02215, USA
    Arch Neurol 58:1865-9. 2001
  6. ncbi request reprint Birthdates of neurons in induced microgyria
    G D Rosen
    Dyslexia Research Laboratory, Beth Israel Hospital, Boston, MA 02215, USA
    Brain Res 727:71-8. 1996
  7. ncbi request reprint Changes in efferent and afferent connectivity in rats with induced cerebrocortical microgyria
    G D Rosen
    Dyslexia Research Laboratory and Charles A Dana Research Institute, Division of Behavioral Neurology, Department of Neurology, Beth Israel Deaconess Medical Center, Boston Massachusetts 02215, USA
    J Comp Neurol 418:423-40. 2000
  8. ncbi request reprint Single cause, polymorphic neuronal migration disorders: an animal model
    G D Rosen
    Department of Neurology, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
    Dev Med Child Neurol 42:652-62. 2000
  9. ncbi request reprint Sex differences in the effects of early neocortical injury on neuronal size distribution of the medial geniculate nucleus in the rat are mediated by perinatal gonadal steroids
    G D Rosen
    Dyslexia Research Laboratory and Charles A Dana Research Institute, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
    Cereb Cortex 9:27-34. 1999
  10. pmc Postnatal analysis of the effect of embryonic knockdown and overexpression of candidate dyslexia susceptibility gene homolog Dcdc2 in the rat
    T J Burbridge
    The Dyslexia Research Laboratory, Division of Behavioral Neurology, Department of Neurology, Beth Israel Deaconess Medical Center, 330 Brookline Avenue, Boston, MA 02215, USA
    Neuroscience 152:723-33. 2008

Collaborators

Detail Information

Publications27

  1. ncbi request reprint [Developmental dyslexia]
    A M Galaburda
    Harvard Medical School, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
    Rev Neurol 36:S3-9. 2003
    ..None of these discoveries have changed the therapeutic modalities in this condition, but it is hoped that this will be the next area of progress...
  2. ncbi request reprint [Williams syndrome. A summary of cognitive, electrophysiological, anatomofunctional, microanatomical and genetic findings]
    A M Galaburda
    Harvard Medical School, Beth Israel Deaconess Medical Center, Boston, MA 02115, USA
    Rev Neurol 36:S132-7. 2003
    ....
  3. ncbi request reprint Williams syndrome: neuronal size and neuronal-packing density in primary visual cortex
    Albert M Galaburda
    Beth Israel Deaconess Medical Center, 330 Brookline Ave, Boston, MA 02215, USA
    Arch Neurol 59:1461-7. 2002
    ..Individuals with WMS demonstrate an unusual and uneven neuropsychological profile showing cognitive and visual spatial deficits juxtaposed with relative language preservation and excellent facial recognition...
  4. ncbi request reprint Developmental disorders of vision
    Albert M Galaburda
    Division of Behavioral Neurology, Harvard Medical School, Beth Israel Deaconess Medical Center, Boston, MA, USA
    Neurol Clin 21:687-707. 2003
    ....
  5. ncbi request reprint Dorsal forebrain anomaly in Williams syndrome
    A M Galaburda
    Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, 330 Brookline Ave, Boston, MA 02215, USA
    Arch Neurol 58:1865-9. 2001
    ..A shortened extent of the dorsal central sulcus has been observed in autopsy specimens...
  6. ncbi request reprint Birthdates of neurons in induced microgyria
    G D Rosen
    Dyslexia Research Laboratory, Beth Israel Hospital, Boston, MA 02215, USA
    Brain Res 727:71-8. 1996
    ..These results are considered in light of recent work demonstrating postnatal neocortical neurogenesis in response to early neocortical injury...
  7. ncbi request reprint Changes in efferent and afferent connectivity in rats with induced cerebrocortical microgyria
    G D Rosen
    Dyslexia Research Laboratory and Charles A Dana Research Institute, Division of Behavioral Neurology, Department of Neurology, Beth Israel Deaconess Medical Center, Boston Massachusetts 02215, USA
    J Comp Neurol 418:423-40. 2000
    ..These connectional changes may help explain disturbances in architecture, physiology, and behavior associated with these focal malformations...
  8. ncbi request reprint Single cause, polymorphic neuronal migration disorders: an animal model
    G D Rosen
    Department of Neurology, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
    Dev Med Child Neurol 42:652-62. 2000
    ..These results suggest that a single etiologic event of varying severity during neuronal migration to the neocortex can induce widely disparate malformations of the cortex...
  9. ncbi request reprint Sex differences in the effects of early neocortical injury on neuronal size distribution of the medial geniculate nucleus in the rat are mediated by perinatal gonadal steroids
    G D Rosen
    Dyslexia Research Laboratory and Charles A Dana Research Institute, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
    Cereb Cortex 9:27-34. 1999
    ..These findings suggest that perinatal gonadal steroids mediate the sex difference in thalamic response to induction of microgyria in the rat cortex...
  10. pmc Postnatal analysis of the effect of embryonic knockdown and overexpression of candidate dyslexia susceptibility gene homolog Dcdc2 in the rat
    T J Burbridge
    The Dyslexia Research Laboratory, Division of Behavioral Neurology, Department of Neurology, Beth Israel Deaconess Medical Center, 330 Brookline Avenue, Boston, MA 02215, USA
    Neuroscience 152:723-33. 2008
    ..These results support the claim that knockdown of Dcdc2 expression results in neuronal migration disorders similar to those seen in the brains of dyslexics...
  11. pmc The effects of embryonic knockdown of the candidate dyslexia susceptibility gene homologue Dyx1c1 on the distribution of GABAergic neurons in the cerebral cortex
    T A Currier
    The Dyslexia Research Laboratory, Division of Cognitive Neurology, Department of Neurology, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
    Neuroscience 172:535-46. 2011
    ....
  12. ncbi request reprint Unilateral induced neocortical malformation and the formation of ipsilateral and contralateral barrel fields
    G D Rosen
    Dyslexia Research Laboratory and Charles A Dana Research Institute and Department of Neurology, Division of Behavioral Neurology, Beth Israel Deaconess Medical Center, 330 Brookline Avenue, Boston, MA 02215, USA
    Neuroscience 103:931-9. 2001
    ..These results are another example of both local and widespread disruption of connectional architecture following induction of focal microgyria...
  13. ncbi request reprint Connectivity of ectopic neurons in the molecular layer of the somatosensory cortex in autoimmune mice
    A R Jenner
    Dyslexia Research Laboratory and Charles A Dana Research Institute, Beth Israel Deaconess Medical Center Program of Neuroscience Harvard Medical School, Boston, MA 02115, USA
    Cereb Cortex 10:1005-13. 2000
    ..These findings confirm the notion that layer I ectopias are anomalously connected by comparison to neurons in homologous cortex, which may underlie widespread dysfunction of brains containing ectopias...
  14. ncbi request reprint Histometric changes and cell death in the thalamus after neonatal neocortical injury in the rat
    G D Rosen
    Dyslexia Research Laboratory and Charles A Dana Research Institute, Department of Neurology, Division of Behavioral Neurology, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
    Neuroscience 141:875-88. 2006
    ..In addition, there was evidence of greater cell death in males at this age. Taken together, these results support the notion that males are more severely affected by early injury to the cerebral cortex than females...
  15. ncbi request reprint Reading impairment in the neuronal migration disorder of periventricular nodular heterotopia
    B S Chang
    Division of Neurogenetics, Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02115, USA
    Neurology 64:799-803. 2005
    ....
  16. ncbi request reprint Relative sparing of primary auditory cortex in Williams Syndrome
    Dorothy P Holinger
    Division of Behavioral Neurology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA 02215, USA
    Brain Res 1037:35-42. 2005
    ..Also, there was less asymmetry in the WS brain. We interpret layers II and VI differences as reflecting increased limbic connectivity in primary auditory cortex of WS...
  17. pmc Disruption of neuronal migration by RNAi of Dyx1c1 results in neocortical and hippocampal malformations
    Glenn D Rosen
    Dyslexia Research Laboratory and Charles A Dana Research Institute, Department of Neurology, Division of Behavioral Neurology, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
    Cereb Cortex 17:2562-72. 2007
    ..These results support the hypothesis that targeted disruption of the candidate dyslexia susceptibility gene, Dyx1c1, results in neuronal migration disorders similar to those seen in the brains of dyslexics...
  18. pmc 3D pattern of brain abnormalities in Williams syndrome visualized using tensor-based morphometry
    Ming Chang Chiang
    Laboratory of Neuro Imaging, Brain Mapping Division, Department of Neurology, UCLA School of Medicine, Los Angeles, CA 90095 7332, USA
    Neuroimage 36:1096-109. 2007
    ..We used tensor-based morphometry (TBM) to visualize the complex pattern of gray/white matter reductions in WS, based on fluid registration of structural brain images...
  19. ncbi request reprint Reduced parietal and visual cortical activation during global processing in Williams syndrome
    Dean Mobbs
    Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA 94305 5719, USA
    Dev Med Child Neurol 49:433-8. 2007
    ..These preliminary results largely confirm previous research findings and neural models implicating neurodevelopmental abnormalities in extended subcortical and cortical visual systems in WS, most notably dorsal-stream pathways...
  20. ncbi request reprint Dyslexia--a molecular disorder of neuronal migration: the 2004 Norman Geschwind Memorial Lecture
    Albert M Galaburda
    Harvard Medical School, Division of Behavioral Neurology and Memory Disorders, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
    Ann Dyslexia 55:151-65. 2005
    ....
  21. ncbi request reprint From genes to behavior in developmental dyslexia
    Albert M Galaburda
    Department of Neurology, Division of Behavioral Neurology, Harvard Medical School, Beth Israel Deaconess Medical Center, 330 Brookline Avenue, Boston, Massachusetts 02215, USA
    Nat Neurosci 9:1213-7. 2006
    ..Thus, we propose a tentative pathway between a genetic effect, developmental brain changes, and perceptual and cognitive deficits associated with dyslexia...
  22. ncbi request reprint Frontostriatal dysfunction during response inhibition in Williams syndrome
    Dean Mobbs
    Center for Interdisciplinary Brain Sciences Research, Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, California 94305 5719, USA
    Biol Psychiatry 62:256-61. 2007
    ..Here we explore the neural systems that mediate response inhibition in WS...
  23. ncbi request reprint Increased local gyrification mapped in Williams syndrome
    Christian Gaser
    Department of Psychiatry, University of Jena, Jena, Germany
    Neuroimage 33:46-54. 2006
    ..The observed gyrification abnormalities in individuals with WS might be related to dysfunctions in neuronal circuits and consequently contribute to the distinct cognitive and behavioral profile accompanying the disorder...
  24. ncbi request reprint Anomalous sylvian fissure morphology in Williams syndrome
    Mark A Eckert
    Department of Otolaryngology Head and Neck Surgery, Medical University of South Carolina, Charleston, 29425, USA
    Neuroimage 33:39-45. 2006
    ....
  25. ncbi request reprint To modulate or not to modulate: differing results in uniquely shaped Williams syndrome brains
    Mark A Eckert
    Department of Otolaryngology Head and Neck Surgery, Medical University of South Carolina, 135 Rutledge Avenue, P O Box 250550, Charleston, SC 29425, USA
    Neuroimage 32:1001-7. 2006
    ....
  26. ncbi request reprint Abnormal cortical complexity and thickness profiles mapped in Williams syndrome
    Paul M Thompson
    Laboratory of Neuroimaging, Brain Mapping Division, Department of Neurology, University of California Los Angeles School of Medicine, Los Angeles, California 90095 1769, USA
    J Neurosci 25:4146-58. 2005
    ..03). These findings visualize cortical zones with altered anatomy in WS, which merit additional study with techniques to assess function and connectivity...
  27. ncbi request reprint Increased gyrification in Williams syndrome: evidence using 3D MRI methods
    J Eric Schmitt
    Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, CA 94305 5719, USA
    Dev Med Child Neurol 44:292-5. 2002
    ..0086) regions. These results suggest that one or more genes in the 7q11.23 region are involved during the critical period when cortical folding occurs, and may be related to the hypothesized dorsal/ventral dissociation in this condition...