Anne B Fulton

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. pmc Development of rod function in term born and former preterm subjects
    Anne B Fulton
    Department of Ophthalmology, Children s Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA
    Optom Vis Sci 86:E653-8. 2009
  2. pmc Retinal degenerative and hypoxic ischemic disease
    Anne B Fulton
    Department of Ophthalmology, Children s Hospital Boston and Harvard Medical School, 300 Longwood Avenue, Boston, MA, 02115, USA
    Doc Ophthalmol 118:55-61. 2009
  3. pmc The cone electroretinogram in retinopathy of prematurity
    Anne B Fulton
    Department of Ophthalmology, Children s Hospital and Harvard Medical School Boston, MA 02115, USA
    Invest Ophthalmol Vis Sci 49:814-9. 2008
  4. pmc The neurovascular retina in retinopathy of prematurity
    Anne B Fulton
    Department of Ophthalmology, Children s Hospital and Harvard Medical School, 300 Longwood Ave, Boston, MA 02115 5737, USA
    Prog Retin Eye Res 28:452-82. 2009
  5. ncbi request reprint Multifocal ERG in subjects with a history of retinopathy of prematurity
    Anne B Fulton
    Department of Ophthalmology, Children s Hospital and Harvard Medical School, Boston, MA 02115, USA
    Doc Ophthalmol 111:7-13. 2005
  6. doi request reprint Visual cycle modulation in neurovascular retinopathy
    James D Akula
    Department of Ophthalmology, Children s Hospital Boston, Boston, MA 02115 5724, USA
    Exp Eye Res 91:153-61. 2010
  7. pmc The oscillatory potentials of the dark-adapted electroretinogram in retinopathy of prematurity
    James D Akula
    Department of Ophthalmology, Children s Hospital Boston, Harvard Medical School, Boston, Massachusetts 02115, USA
    Invest Ophthalmol Vis Sci 48:5788-97. 2007
  8. pmc Retinal degeneration in children: dark adapted visual threshold and arteriolar diameter
    Ronald M Hansen
    Department of Ophthalmology, Children s Hospital and Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, USA
    Vision Res 48:325-31. 2008
  9. ncbi request reprint Development of the electroretinographic oscillatory potentials in normal and ROP rats
    Kegao Liu
    Department of Ophthalmology, Children s Hospital and Harvard Medical School, Boston, Massachusetts, USA
    Invest Ophthalmol Vis Sci 47:5447-52. 2006
  10. pmc Long-term effects of retinopathy of prematurity (ROP) on rod and rod-driven function
    Maureen E Harris
    Department of Ophthalmology, Children s Hospital and Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, USA
    Doc Ophthalmol 122:19-27. 2011

Research Grants

Collaborators

  • Ronald M Hansen
  • Anne Moskowitz
  • Susanne C Beck
  • Naoyuki Tanimoto
  • Aparna Raghuram
  • Deborah K Vanderveen
  • Radouil Tzekov
  • Edda Fahl
  • Mira Lim
  • D X Hammer
  • James D Akula
  • Tara L Favazza
  • Julie A Mocko
  • Kegao Liu
  • Ilan Y Benador
  • Ellen R Elias
  • Rachel M Griffith
  • Maureen E Harris
  • Deirdre Garry
  • Tanya C Vyhovsky
  • Shivi Agrawal
  • Michael S Kleinman
  • Ming Lu
  • Amber M Barnaby
  • Mira Irons
  • M Elena Martinez-Perez
  • Rony Gelman
  • Efthymia K Tsina
  • Gerald F Cox
  • John Chunguang Jiang
  • Linda L Cooper
  • Mathias W Seeliger
  • Hu Li
  • Vithiyanjali Sothilingam
  • Nan Zhang
  • Christina Seide
  • Marina Garcia Garrido
  • Robert J Munro
  • David McGee
  • Ana L Asturias
  • Ryo Kubota
  • D Luisa Mayer
  • Susan E Eklund
  • Melody J Cunningham
  • Christopher Falk
  • Deborah L Marsden
  • Nicole B Quinn
  • Nicole Quinn
  • Frances E Dougherty
  • Xavier Reynaud
  • Basil T Darras
  • Mark Korson
  • John M Shoffner

Detail Information

Publications38

  1. pmc Development of rod function in term born and former preterm subjects
    Anne B Fulton
    Department of Ophthalmology, Children s Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA
    Optom Vis Sci 86:E653-8. 2009
    ..To provide an overview of some of our electroretinographic (ERG) and psychophysical studies of normal development of rod function and their application to retinopathy of prematurity (ROP)...
  2. pmc Retinal degenerative and hypoxic ischemic disease
    Anne B Fulton
    Department of Ophthalmology, Children s Hospital Boston and Harvard Medical School, 300 Longwood Avenue, Boston, MA, 02115, USA
    Doc Ophthalmol 118:55-61. 2009
    ..Beneficial pharmaceutical interventions may be measured in improved visual outcome as well as lessening of the vascular abnormalities...
  3. pmc The cone electroretinogram in retinopathy of prematurity
    Anne B Fulton
    Department of Ophthalmology, Children s Hospital and Harvard Medical School Boston, MA 02115, USA
    Invest Ophthalmol Vis Sci 49:814-9. 2008
    ..To test the hypothesis that retinopathy of prematurity (ROP) affects the cone photoreceptors less than the rod photoreceptors...
  4. pmc The neurovascular retina in retinopathy of prematurity
    Anne B Fulton
    Department of Ophthalmology, Children s Hospital and Harvard Medical School, 300 Longwood Ave, Boston, MA 02115 5737, USA
    Prog Retin Eye Res 28:452-82. 2009
    ..The data from human subjects and rat models identify photoreceptor and post-receptor targets for interventions that promise improved outcomes for children at risk for ROP...
  5. ncbi request reprint Multifocal ERG in subjects with a history of retinopathy of prematurity
    Anne B Fulton
    Department of Ophthalmology, Children s Hospital and Harvard Medical School, Boston, MA 02115, USA
    Doc Ophthalmol 111:7-13. 2005
    ..Investigate the function of the central retina in subjects with a history of retinopathy of prematurity (ROP)...
  6. doi request reprint Visual cycle modulation in neurovascular retinopathy
    James D Akula
    Department of Ophthalmology, Children s Hospital Boston, Boston, MA 02115 5724, USA
    Exp Eye Res 91:153-61. 2010
    ..There was no evidence of negative alteration of photoreceptor function consequent to VCM treatment. This finding implicates the rods as a possible therapeutic target in neurovascular diseases such as ROP...
  7. pmc The oscillatory potentials of the dark-adapted electroretinogram in retinopathy of prematurity
    James D Akula
    Department of Ophthalmology, Children s Hospital Boston, Harvard Medical School, Boston, Massachusetts 02115, USA
    Invest Ophthalmol Vis Sci 48:5788-97. 2007
    ..To study the development of the electroretinographic (ERG) oscillatory potentials (OPs) in two rat models of ROP and in human subjects with a history of ROP...
  8. pmc Retinal degeneration in children: dark adapted visual threshold and arteriolar diameter
    Ronald M Hansen
    Department of Ophthalmology, Children s Hospital and Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, USA
    Vision Res 48:325-31. 2008
    ..Higher DATs were associated with narrower arterioles. Such non-invasive procedures can document the natural history of these retinal diseases and have the potential to assess response to future treatment...
  9. ncbi request reprint Development of the electroretinographic oscillatory potentials in normal and ROP rats
    Kegao Liu
    Department of Ophthalmology, Children s Hospital and Harvard Medical School, Boston, Massachusetts, USA
    Invest Ophthalmol Vis Sci 47:5447-52. 2006
    ..To study the development of the electroretinographic (ERG) oscillatory potentials (OPs) in rats and to compare normal OPs with those in a rat model of retinopathy of prematurity (ROP)...
  10. pmc Long-term effects of retinopathy of prematurity (ROP) on rod and rod-driven function
    Maureen E Harris
    Department of Ophthalmology, Children s Hospital and Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, USA
    Doc Ophthalmol 122:19-27. 2011
    ..The data are evidence that sensitivity of the post-receptor retina improves in those with a history of mild ROP. We speculate that beneficial reorganization of the post-receptor neural circuitry occurs in mild but not in severe ROP...
  11. doi request reprint The anatomy of the rat eye with oxygen-induced retinopathy
    James D Akula
    Department of Ophthalmology, Children s Hospital Boston, Boston, MA 02115, USA
    Doc Ophthalmol 120:41-50. 2010
    ..The ratio of anterior to posterior axial-lengths ranged from 0.45 in controls through 0.37 in the 75 model to 0.32 in the 50/10 model. Thus, eye growth is altered in these rat models of ROP...
  12. pmc The neurovascular relation in oxygen-induced retinopathy
    James D Akula
    Department of Ophthalmology, Children s Hospital Boston, Boston, MA 02115, USA
    Mol Vis 14:2499-508. 2008
    ....
  13. doi request reprint Electroretinographic (ERG) responses in pediatric patients using vigabatrin
    Anne Moskowitz
    Department of Ophthalmology, Children s Hospital and Harvard Medical School, Boston, MA 02115, USA
    Doc Ophthalmol 124:197-209. 2012
    ..We caution against over-reliance on the ERG to monitor pediatric patients for VGB toxicity and recommend further development of a reliable test of peripheral vision to supplant ERG testing...
  14. pmc Deactivation of the rod response in retinopathy of prematurity
    Ronald M Hansen
    Department of Ophthalmology, Children s Hospital, Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, USA
    Doc Ophthalmol 121:29-35. 2010
    ..Prolonged deactivation in these mature ROP subjects may indicate lack of maturation of the deactivation process (t(50)) or progressive compromise of retinal function with increasing age...
  15. pmc Rod and rod-driven function in achromatopsia and blue cone monochromatism
    Anne Moskowitz
    Department of Ophthalmology, Children s Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA
    Invest Ophthalmol Vis Sci 50:950-8. 2009
    ..To evaluate rod photoreceptor and postreceptor retinal function in pediatric patients with achromatopsia (ACHR) and blue cone monochromatism (BCM) using contemporary electroretinographic (ERG) procedures...
  16. ncbi request reprint Rod photoreceptor function predicts blood vessel abnormality in retinopathy of prematurity
    James D Akula
    Department of Ophthalmology, Children s Hospital Boston and Harvard Medical School, Boston, Massachusetts 02115, USA
    Invest Ophthalmol Vis Sci 48:4351-9. 2007
    ..To test the hypothesis that early rod dysfunction predicts the blood vessel abnormalities that are the clinical hallmark of retinopathy of prematurity (ROP)...
  17. pmc Development of scotopic visual thresholds in retinopathy of prematurity
    Amber M Barnaby
    Department of Ophthalmology, Children s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
    Invest Ophthalmol Vis Sci 48:4854-60. 2007
    ..To test the hypothesis that the late-maturing parafoveal rod photoreceptors are more vulnerable than peripheral rods to the effects of retinopathy of prematurity (ROP)...
  18. ncbi request reprint The retinal vasculature and function of the neural retina in a rat model of retinopathy of prematurity
    Kegao Liu
    Department of Ophthalmology, Children s Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA
    Invest Ophthalmol Vis Sci 47:2639-47. 2006
    ..In a rat model of retinopathy of prematurity (ROP), the retinal vasculature and function of the neural retina were studied longitudinally. Vascular and neural parameters were evaluated for significant relationships...
  19. ncbi request reprint ERG oscillatory potentials in infants
    Anne Moskowitz
    Department of Ophthalmology, Children s Hospital and Harvard Medical School, Boston, MA, USA
    Doc Ophthalmol 110:265-70. 2005
    ..Study the scotopic and photopic oscillatory potentials (OPs) of the electroretinogram (ERG) in 10-week old infants...
  20. ncbi request reprint Recovery of the rod photoresponse in infants
    Ronald M Hansen
    Department of Ophthalmology, Children s Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA
    Invest Ophthalmol Vis Sci 46:764-8. 2005
    ..Rhodopsin content increases and scales the parameters of the activation of rod phototransduction as rods develop. However, little is known about the kinetics of deactivation in the rods of young infants...
  21. ncbi request reprint Recovery of the rod photoresponse in infant rats
    Anne B Fulton
    Department of Ophthalmology, Children s Hospital and Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, USA
    Vision Res 43:3081-5. 2003
    ..The kinetics of rod cell recovery are likely the same in infants and adults...
  22. pmc Photoreceptor and postreceptor responses in congenital stationary night blindness
    Aparna Raghuram
    Department of Ophthalmology, Boston Children s Hospital, Boston, Massachusetts 02215, USA
    Invest Ophthalmol Vis Sci 54:4648-58. 2013
    ..To investigate photoreceptor and postreceptor retinal function in patients with congenital stationary night blindness (CSNB)...
  23. ncbi request reprint Retinal function in carriers of Bardet-Biedl syndrome
    Gerald F Cox
    Department of Medicine, Children s Hospital, Boston, Mass, USA
    Arch Ophthalmol 121:804-10. 2003
    ..To test the hypothesis that carriers of Bardet-Biedl syndrome have abnormal rod-mediated responses...
  24. pmc Multifocal ERG responses in infants
    Ronald M Hansen
    Department of Ophthalmology, Children s Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA
    Invest Ophthalmol Vis Sci 50:470-5. 2009
    ..To assess function of the central retina in 10-week-old infants, multifocal electroretinograms (mfERGs) were recorded. mfERG responses represent postreceptor retinal activity...
  25. pmc Cone ERG responses in patients with Smith-Lemli-Opitz Syndrome (SLOS)
    Deirdre Garry
    Department of Ophthalmology, Children s Hospital Boston, Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, USA
    Doc Ophthalmol 121:85-91. 2010
    ..To evaluate cone and cone-driven retinal function in patients with Smith-Lemli-Opitz syndrome (SLOS), a condition characterized by low cholesterol. Rod and rod-driven function in patients with SLOS are known to be abnormal...
  26. pmc Development of the cone ERG in infants
    Ronald M Hansen
    Department of Ophthalmology, Children s Hospital and Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, USA
    Invest Ophthalmol Vis Sci 46:3458-62. 2005
    ..To assess cone photoreceptor and cone-mediated postreceptoral retinal function in infants...
  27. pmc Alterations of the tunica vasculosa lentis in the rat model of retinopathy of prematurity
    Tara L Favazza
    Department of Ophthalmology, Boston Children s Hospital, 300 Longwood Avenue, Fegan 4, Boston, MA, 02115, USA
    Doc Ophthalmol 127:3-11. 2013
    ..Although the clinical hallmark of ROP is abnormal retinal blood vessels, the vessels of the anterior segment, including the TVL, are also altered...
  28. ncbi request reprint Rod photoreceptor function in children with mitochondrial disorders
    Linda L Cooper
    Department of Ophthalmology, Children s Hospital Boston and Harvard Medical School, Mass 02115, USA
    Arch Ophthalmol 120:1055-62. 2002
    ..To test the hypothesis that function of the rod photoreceptors is abnormal in pediatric patients with mitochondrial disorders...
  29. ncbi request reprint Background adaptation in a rat model of retinopathy of prematurity
    John Chunguang Jiang
    Department of Ophthalmology, Children s Hospital and Harvard Medical School, Boston, MA 02115, USA
    Doc Ophthalmol 104:97-105. 2002
    ..The effect of the background light is consistent with receptoral disease causing low dark adapted b-wave sensitivity in ROP rats...
  30. ncbi request reprint Maculopathy and retinal degeneration in cobalamin C methylmalonic aciduria and homocystinuria
    Efthymia K Tsina
    Department of Ophthalmology, Children s Hospital Boston, 300 Longwood Avenue, Boston, MA 02115, USA
    Arch Ophthalmol 123:1143-6. 2005
  31. pmc Next-generation sequencing analysis of gene regulation in the rat model of retinopathy of prematurity
    Rachel M Griffith
    Department of Ophthalmology, Boston Children s Hospital, 300 Longwood Avenue, Fegan 4, Boston, MA, 02115, USA
    Doc Ophthalmol 127:13-31. 2013
    ..The purpose of this study was to identify the genes, biochemical signaling pathways, and biological themes involved in the pathogenesis of retinopathy of prematurity (ROP)...
  32. ncbi request reprint Rod photoreceptor responses in children with Smith-Lemli-Opitz syndrome
    Ellen R Elias
    Departments of Ophthalmology and Medicine, Children s Hospital, New England College of Optometry, Boston, Massachusetts, USA
    Arch Ophthalmol 121:1738-43. 2003
    ....
  33. ncbi request reprint Development of ERG responses: the ISCEV rod, maximal and cone responses in normal subjects
    Anne B Fulton
    Department of Ophthalmology, The Children s Hospital, Boston, MA 02115, USA
    Doc Ophthalmol 107:235-41. 2003
    ..Summarize ISCEV ERG responses from normal infants and children...
  34. ncbi request reprint Development of visual acuity in children with cerebral visual impairment
    Mira Lim
    Department of Ophthalmology, Children s Hospital and Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, USA
    Arch Ophthalmol 123:1215-20. 2005
    ..To study the development of visual acuity in term-born children with cerebral visual impairment and a history of neonatal hypoxic-ischemic encephalopathy...
  35. pmc Diagnosis of plus disease in retinopathy of prematurity using Retinal Image multiScale Analysis
    Rony Gelman
    Department of Ophthalmology, Children s Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA
    Invest Ophthalmol Vis Sci 46:4734-8. 2005
    ..To evaluate a semiautomated image analysis software package, Retinal Image multiScale Analysis (RISA), for the diagnosis of plus disease in preterm infants with retinopathy of prematurity (ROP)...
  36. doi request reprint Visual fields in young children treated with vigabatrin
    Shivi Agrawal
    Department of Ophthalmology, Children s Hospital, Boston and Harvard Medical School, Boston, Massachusetts 02115, USA
    Optom Vis Sci 86:767-73. 2009
    ..VGB is an antiepileptic medication that is associated with visual field constriction...
  37. pmc Foveal fine structure in retinopathy of prematurity: an adaptive optics Fourier domain optical coherence tomography study
    Daniel X Hammer
    Physical Sciences Inc, 20 New England Business Center, Andover, MA 01810, USA
    Invest Ophthalmol Vis Sci 49:2061-70. 2008
    ..To describe the fine structure of the fovea in subjects with a history of mild retinopathy of prematurity (ROP) using adaptive optics-Fourier domain optical coherence tomography (AO-FDOCT)...
  38. ncbi request reprint Effects of desferoxamine on retinal and visual function
    Ming Lu
    Arch Ophthalmol 125:1581-2. 2007

Research Grants17

  1. PHOTORECEPTOR FUNCTION IN RETINOPATHY OF PREMATURITY
    Anne Fulton; Fiscal Year: 2007
    ..This information may, in the future, change management of ROP in infancy and in children with a history of ROP. ..
  2. A System for Study of Pediatric Visual Pathways
    Anne Fulton; Fiscal Year: 2004
    ..With these studies as a whole, we expect to obtain new knowledge about the processes that govern vision and its development in these pediatric disorders. ..
  3. PHOTORECEPTOR FUNCTION IN RETINOPATHY OF PREMATURITY
    Anne Fulton; Fiscal Year: 2004
    ..This project, based on an entirely new perspective of ROP, will lead not only to much more information about retinal and visual function in ROP, but also to new knowledge about fundamental ROP disease processes. ..
  4. Retcam 120 Wide Field Digital Imaging System
    Anne Fulton; Fiscal Year: 2002
    ..The minor users will take advantage of the wide field images as well as the highly magnified views of the macula and optic nerve head (optic disc), including the fluorescein capability. ..
  5. DEVELOPMENT OF PHOTORECEPTOR FUNCTION
    Anne Fulton; Fiscal Year: 1999
    ..Longitudinal measures of the visual thresholds at 10 degree and 30 degree eccentricities will test the hypothesis that the near central threshold has an abnormally slow course of development in those with a history of ROP. ..
  6. PHOTORECEPTOR FUNCTION IN RETINOPATHY OF PREMATURITY
    Anne B Fulton; Fiscal Year: 2010
    ..This information may, in the future, change management of ROP in infancy and in children with a history of ROP. ..