Research Topics
| Frances R FrankenburgSummaryAffiliation: Harvard University Country: USA Publications
| Collaborators
|
Detail Information
Publications
The essential nature of borderline psychopathologyMary C Zanarini
Laboratory of Adult Development, McLean Hospital, Belmont, Massachusetts 024778, USA
J Pers Disord 21:518-35. 2007..The treatment and nosological implications of this model are discussed...
Divalproex sodium treatment of women with borderline personality disorder and bipolar II disorder: a double-blind placebo-controlled pilot studyFrances R Frankenburg
Laboratory for the Study of Adult Development, McLean Hospital, Belmont, MA 02478, USA
J Clin Psychiatry 63:442-6. 2002..The intent of this study was to compare the efficacy and safety of divalproex sodium and placebo in the treatment of women with borderline personality disorder and comorbid bipolar II disorder...
Obesity and obesity-related illnesses in borderline patientsFrances R Frankenburg
Laboratory for the Study of Adult Development, McLean Hospital, Belmont, MA 02478, USA
J Pers Disord 20:71-80. 2006..These results suggest that obesity is common among heavily treated borderline patients and is associated with a number of chronic medical disorders...
The association between borderline personality disorder and chronic medical illnesses, poor health-related lifestyle choices, and costly forms of health care utilizationFrances R Frankenburg
Laboratory for the Study of Adult Development, McLean Hospital, Belmont, and the Department of Psychiatry, Harvard Medical School, Boston, MA 02478, USA
J Clin Psychiatry 65:1660-5. 2004..The purpose of this study was to compare the physical health, lifestyle choices affecting physical health, and health care utilization of patients with remitted and nonremitted borderline personality disorder...
The subsyndromal phenomenology of borderline personality disorder: a 10-year follow-up studyMary C Zanarini
Laboratory for the Study of Adult Development and the Psychiatric Epidemiology Research Program, McLean Hospital, 115 Mill St, Belmont 02478, and the Department of Psychiatry, Harvard Medical School, Boston, MA, USA
Am J Psychiatry 164:929-35. 2007..The purpose of this study was to characterize the course of 24 symptoms of borderline personality disorder in terms of time to remission...
Prediction of the 10-year course of borderline personality disorderMary C Zanarini
Laboratory for the Study for Adult Development, McLean Hospital, 115 Mill St, Belmont, MA 02478, USA
Am J Psychiatry 163:827-32. 2006..The purpose of this study was to determine the most clinically relevant baseline predictors of time to remission for patients with borderline personality disorder...
The course of adult experiences of abuse in patients with borderline personality disorder and Axis II comparison subjects: a 10-year follow-up studyAmelia McGowan
McLean Hospital, 115 Mill St, Belmont, MA 02478, USA
J Pers Disord 26:192-202. 2012..Contrastingly, they were relatively uncommon for physical and sexual abuse (<30%), suggesting that verbal and emotional abuse represent more stable forms of abuse...
Axis I comorbidity in patients with borderline personality disorder: 6-year follow-up and prediction of time to remissionMary C Zanarini
McLean Hospital, 115 Mill St, Belmont, MA 02478, USA
Am J Psychiatry 161:2108-14. 2004..The purpose of this study was to assess the prevalence of axis I disorders among patients with borderline personality disorder over 6 years of prospective follow-up...
Sexual relationship difficulties among borderline patients and axis II comparison subjectsMary C Zanarini
Department of Psychiatry, McLean Hospital and Harvard Medical School, 115 Mill Street, Belmont, MA 02478, USA
J Nerv Ment Dis 191:479-82. 2003
Adult experiences of abuse reported by borderline patients and Axis II comparison subjects over six years of prospective follow-upMary C Zanarini
Laboratory for the Study for Adult Development, McLean Hospital, 115 Mill Street, Belmont, MA 02478, USA
J Nerv Ment Dis 193:412-6. 2005..They also suggest that adult experiences of abuse are strongly associated with a failure to remit from borderline personality disorder...
Attainment and stability of sustained symptomatic remission and recovery among patients with borderline personality disorder and axis II comparison subjects: a 16-year prospective follow-up studyMary C Zanarini
McLean Hospital, Belmont, MA, USA lean harvard edu
Am J Psychiatry 169:476-83. 2012....
Family history study of the familial coaggregation of borderline personality disorder with axis I and nonborderline dramatic cluster axis II disordersMary C Zanarini
Laboratory for the Study for Adult Development and the Psychiatric Epidemiology Research Program, McLean Hospital, and the Department of Psychiatry, Harvard Medical School, USA
J Pers Disord 23:357-69. 2009..Taken together, the results of this study suggest that common familial factors, particularly in the areas of affective disturbance and impulsivity, contribute to borderline personality disorder...
A longitudinal study of the 10-year course of interpersonal features in borderline personality disorderLois W Choi-Kain
Laboratory for the Study of Adult Development, McLean Hospital, Belmont, Massachusetts 02478, USA
J Pers Disord 24:365-76. 2010..The behavioral interpersonal features of BPD remit rapidly, while core affectively-oriented features related to intolerance of aloneness and conflicts over dependency are more persistent...
Relationship between cumulative BMI and symptomatic, psychosocial, and medical outcomes in patients with borderline personality disorderFrances R Frankenburg
Laboratory for the Study of Adult Development, McLean Hospital
J Pers Disord 25:421-31. 2011..Increases in cumulative BMI may be a marker for adverse symptomatic, functional, and medical outcomes in patients with BPD...
The longitudinal course of borderline psychopathology: 6-year prospective follow-up of the phenomenology of borderline personality disorderMary C Zanarini
Laboratory for the Study for Adult Development, McLean Hospital, MA, USA
Am J Psychiatry 160:274-83. 2003..The syndromal and subsyndromal phenomenology of borderline personality disorder was tracked over 6 years of prospective follow-up...
The course of eating disorders in patients with borderline personality disorder: a 10-year follow-up studyMary C Zanarini
McLean Hospital, Belmont, Massachusetts 02478, USA
Int J Eat Disord 43:226-32. 2010..The purpose of this study was to describe the longitudinal course of eating disorders in patients with borderline personality disorder...
The 10-year course of social security disability income reported by patients with borderline personality disorder and axis II comparison subjectsMary C Zanarini
Laboratory for the Study of Adult Development, McLean Hospital, and the Department of Psychiatry, Harvard Medical School, USA
J Pers Disord 23:346-56. 2009..The results of this study suggest that receiving SSDI benefits is both more common and more fluid over time for patients with BPD than previously known...
Reported childhood onset of self-mutilation among borderline patientsMary C Zanarini
Laboratory for the Study of Adult Development, McLean Hospital, Belmont, MA 02478, USA
J Pers Disord 20:9-15. 2006..The results of this study suggest that a sizable minority of borderline patients first engage in self-harm as children and that the course of their self-mutilation may be particularly malignant...
The McLean Study of Adult Development (MSAD): overview and implications of the first six years of prospective follow-upMary C Zanarini
Laboratory for the Study of Adult Development, McLean Hospital, and the Department of Psychiatry, Harvard Medical School, USA
J Pers Disord 19:505-23. 2005..Taken together, these results suggest that the prognosis for BPD is better than previously recognized...
Psychosocial functioning of borderline patients and axis II comparison subjects followed prospectively for six yearsMary C Zanarini
Laboratory for the Study for Adult Development, McLean Hospital, Belmont, MA 02478, USA
J Pers Disord 19:19-29. 2005..27% at 6 year follow-up). Taken together, the results of this study suggest that psychosocial improvement is both common among borderline patients and strongly related to their symptomatic status...
A preliminary, randomized trial of fluoxetine, olanzapine, and the olanzapine-fluoxetine combination in women with borderline personality disorderMary C Zanarini
Laboratory for the Study of Adult Development, McLean Hospital, Belmont, MA 02478, USA
J Clin Psychiatry 65:903-7. 2004....
Time to attainment of recovery from borderline personality disorder and stability of recovery: A 10-year prospective follow-up studyMary C Zanarini
McLean Hospital, Belmont, MA 02478, USA
Am J Psychiatry 167:663-7. 2010..The purposes of this study were to determine time to attainment of recovery from borderline personality disorder and to assess the stability of recovery...
Predictors of self-mutilation in patients with borderline personality disorder: A 10-year follow-up studyMary C Zanarini
McLean Hospital, 115 Mill Street, Belmont, MA 02478, United States
J Psychiatr Res 45:823-8. 2011..The purpose of this study was to determine the most clinically relevant baseline and time-varying predictors of self-mutilation over 10 years of prospective follow-up among patients with BPD...
omega-3 Fatty acid treatment of women with borderline personality disorder: a double-blind, placebo-controlled pilot studyMary C Zanarini
Laboratory for the Study of Adult Development, McLean Hospital, Belmont, MA 02478, USA
Am J Psychiatry 160:167-9. 2003..The purpose of this study was to compare the efficacy of ethyl-eicosapentaenoic acid (E-EPA) and placebo in the treatment of female subjects with borderline personality disorder...
A screening measure for BPD: the McLean Screening Instrument for Borderline Personality Disorder (MSI-BPD)Mary C Zanarini
Laboratory for the Study for Adult Development, McLean Hospital, Belmont, MA 02478, USA
J Pers Disord 17:568-73. 2003..93 at a cutoff of 7 for the 63 subjects who were 25 years old or younger. The results of this study suggest that the MSI-BPD may be a useful screening instrument for the presence of DSM-IV borderline personality disorder...
Mental health service utilization by borderline personality disorder patients and Axis II comparison subjects followed prospectively for 6 yearsMary C Zanarini
Laboratory for the Study of Adult Development, McLean Hospital, Belmont, MA 02478, USA
J Clin Psychiatry 65:28-36. 2004..The purpose of this study was to describe the psychiatric treatment received by a well-defined sample of patients with borderline personality disorder and Axis II comparison subjects over 6 years of prospective follow-up...
Sedative-hypnotic use in patients with borderline personality disorder and axis II comparison subjectsDavid T Plante
Division of Sleep Medicine, Harvard Medicial School, Boston, MA, USA
J Pers Disord 23:563-71. 2009..81, 95% CI: 1.33-5.95). These results indicate that sedative-hypnotic use is greater among BPD than OPD subjects. They also confirm clinical observations that subjective sleep disturbance is a significant problem in BPD...
Borderline psychopathology in the first-degree relatives of borderline and axis II comparison probandsMary C Zanarini
The Laboratory for the Study for Adult Development, McLean Hospital, and the Department of Psychiatry, Harvard Medical School, Belmont, MA 02478, USA
J Pers Disord 18:439-47. 2004..Taken together, the results of this study suggest that the subsyndromal phenomenology of BPD may be more common than the borderline diagnosis itself...
Zanarini Rating Scale for Borderline Personality Disorder (ZAN-BPD): a continuous measure of DSM-IV borderline psychopathologyMary C Zanarini
Department of Psychiatry, McLean Hospital, Belmont, Massachusetts 02478, USA
J Pers Disord 17:233-42. 2003..Taken together, the results of this study suggest that the ZAN-BPD is a promising clinician-administered scale for the assessment of change in borderline psychopathology over time...
Defense mechanisms associated with borderline personality disorderMary C Zanarini
McLean Hospital, 115 Mill Street, Belmont, Massachusetts 02478, USA
J Pers Disord 23:113-21. 2009..They also suggest that the defensive triad of acting out, emotional hypochondriasis, and undoing may serve as a useful clinical marker for the borderline diagnosis, particularly in settings where the base rate of the disorder is high...
Severity of reported childhood sexual abuse and its relationship to severity of borderline psychopathology and psychosocial impairment among borderline inpatientsMary C Zanarini
The Laboratory for the Study for Adult Development, McLean Hospital, 115 Mill Street, Belmont, Massachusetts 02478, USA
J Nerv Ment Dis 190:381-7. 2002....
A preliminary, randomized trial of psychoeducation for women with borderline personality disorderMary C Zanarini
Laboratory for the Study of Adult Development, McLean Hospital, Belmont, MA 02478, USA
J Pers Disord 22:284-90. 2008..They also suggest that such instruction may prove to be a useful and cost-efficient form of pre-treatment...
The course of anxiety disorders other than PTSD in patients with borderline personality disorder and Axis II comparison subjects: a 10-year follow-up studyMerav H Silverman
McLean Hospital, Belmont, MA 02478, USA
J Pers Disord 26:804-14. 2012..These results suggest that anxiety disorders are very common over time among borderline patients. They also suggest that these disorders have an intermittent course among those with BPD...
Inter-rater and test-retest reliability of the Revised Diagnostic Interview for BorderlinesMary C Zanarini
Laboratory for the Study of Adult Development, McLean Hospital, 115 Mill St, Belmont, MA 02478, USA
J Pers Disord 16:270-6. 2002..They also suggest that excellent reliability, once achieved, can be maintained over time for both the syndromal and subsyndromal phenomenology of BPD...
Personality disorders and medical comorbidityFrances R Frankenburg
Boston University School of Medicine, Edith Nourse Rogers Memorial VAMC, Bedford, MA 01730, USA
Curr Opin Psychiatry 19:428-31. 2006..Personality disorders are not usually thought of as being associated with medical comorbidity. Research shows that medical comorbidity in personality disorders is clinically important...
Pharmacological treatment of delirium in the intensive care unitFrances R Frankenburg
JAMA 292:168; author reply 168-9. 2004
