W Fawzi

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. pmc Multivitamin supplementation in HIV infected adults initiating antiretroviral therapy in Uganda: the protocol for a randomized double blinded placebo controlled efficacy trial
    David Guwatudde
    School of Public Health, Makerere University College of Health Sciences, PO Box 7072, Kampala, Uganda
    BMC Infect Dis 12:304. 2012
  2. pmc Efficacy of early neonatal vitamin A supplementation in reducing mortality during infancy in Ghana, India and Tanzania: study protocol for a randomized controlled trial
    Rajiv Bahl
    Department of Maternal Newborn Child and Adolescent Health, World Health Organization, Avenue Appia 20, 1211 Geneva 27, Switzerland
    Trials 13:22. 2012
  3. pmc Population Health Metrics Research Consortium gold standard verbal autopsy validation study: design, implementation, and development of analysis datasets
    Christopher Jl Murray
    Institute for Health Metrics and Evaluation, University of Washington, 2301 Fifth Ave, Suite 600, Seattle, WA 98121, USA
    Popul Health Metr 9:27. 2011
  4. pmc A randomized trial of multivitamin supplementation in children with tuberculosis in Tanzania
    Saurabh Mehta
    Division of Nutritional Sciences, Cornell University, Ithaca, NY 14853, USA
    Nutr J 10:120. 2011
  5. pmc Primary antimicrobial resistance among Mycobacterium tuberculosis isolates from HIV seropositive and HIV seronegative patients in Dar es Salaam Tanzania
    Willy Urassa
    Departments of Microbiology and Immunology, Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania
    BMC Res Notes 1:58. 2008
  6. pmc Factors associated with mortality in HIV-infected and uninfected patients with pulmonary tuberculosis
    Ferdinand M Mugusi
    Department of Internal Medicine, Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania
    BMC Public Health 9:409. 2009
  7. pmc Anemia and growth failure among HIV-infected children in India: a retrospective analysis
    Anita Shet
    Department of Pediatrics, St John s National Academy of Health Sciences, Bangalore, India
    BMC Pediatr 9:37. 2009
  8. pmc Gender-related differences in the prevalence of cardiovascular disease risk factors and their correlates in urban Tanzania
    Marina A Njelekela
    Department of Physiology, Muhimbili University of Health and Allied Sciences, PO Box 65001, Dar es Salaam, Tanzania
    BMC Cardiovasc Disord 9:30. 2009
  9. ncbi request reprint Effect of providing vitamin supplements to human immunodeficiency virus-infected, lactating mothers on the child's morbidity and CD4+ cell counts
    Wafaie W Fawzi
    Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts 02115, USA
    Clin Infect Dis 36:1053-62. 2003
  10. ncbi request reprint Effect of maternal multivitamin supplementation on the mental and psychomotor development of children who are born to HIV-1-infected mothers in Tanzania
    Nuala McGrath
    Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
    Pediatrics 117:e216-25. 2006

Collaborators

Detail Information

Publications93

  1. pmc Multivitamin supplementation in HIV infected adults initiating antiretroviral therapy in Uganda: the protocol for a randomized double blinded placebo controlled efficacy trial
    David Guwatudde
    School of Public Health, Makerere University College of Health Sciences, PO Box 7072, Kampala, Uganda
    BMC Infect Dis 12:304. 2012
    ..We propose to evaluate the efficacy of a single recommended daily allowance (RDA) of micronutrients (including vitamins B-complex, C, and E) in slowing disease progression among HIV-infected adults receiving HAART in Uganda...
  2. pmc Efficacy of early neonatal vitamin A supplementation in reducing mortality during infancy in Ghana, India and Tanzania: study protocol for a randomized controlled trial
    Rajiv Bahl
    Department of Maternal Newborn Child and Adolescent Health, World Health Organization, Avenue Appia 20, 1211 Geneva 27, Switzerland
    Trials 13:22. 2012
    ....
  3. pmc Population Health Metrics Research Consortium gold standard verbal autopsy validation study: design, implementation, and development of analysis datasets
    Christopher Jl Murray
    Institute for Health Metrics and Evaluation, University of Washington, 2301 Fifth Ave, Suite 600, Seattle, WA 98121, USA
    Popul Health Metr 9:27. 2011
    ..abstract:..
  4. pmc A randomized trial of multivitamin supplementation in children with tuberculosis in Tanzania
    Saurabh Mehta
    Division of Nutritional Sciences, Cornell University, Ithaca, NY 14853, USA
    Nutr J 10:120. 2011
    ..Multivitamin supplementation has been proposed as a means to enhance the health of these children; however, the efficacy of such an intervention has not been examined adequately...
  5. pmc Primary antimicrobial resistance among Mycobacterium tuberculosis isolates from HIV seropositive and HIV seronegative patients in Dar es Salaam Tanzania
    Willy Urassa
    Departments of Microbiology and Immunology, Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania
    BMC Res Notes 1:58. 2008
    ..tuberculosis including MDR vary greatly. The varied drug-resistance patterns make continuous surveillance of drug resistance an essential component of tuberculosis control program...
  6. pmc Factors associated with mortality in HIV-infected and uninfected patients with pulmonary tuberculosis
    Ferdinand M Mugusi
    Department of Internal Medicine, Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania
    BMC Public Health 9:409. 2009
    ..This study investigates factors associated with mortality including patients' HIV sero-status, CD4 cell count, laboratory, nutritional and demographic characteristics in AFB smear positive pulmonary TB patients...
  7. pmc Anemia and growth failure among HIV-infected children in India: a retrospective analysis
    Anita Shet
    Department of Pediatrics, St John s National Academy of Health Sciences, Bangalore, India
    BMC Pediatr 9:37. 2009
    ..Anemia and poor nutrition have been previously described as independent risk factors for death among HIV-infected children. We sought to describe nutritional status, anemia burden and HIV disease correlates among infected children in India...
  8. pmc Gender-related differences in the prevalence of cardiovascular disease risk factors and their correlates in urban Tanzania
    Marina A Njelekela
    Department of Physiology, Muhimbili University of Health and Allied Sciences, PO Box 65001, Dar es Salaam, Tanzania
    BMC Cardiovasc Disord 9:30. 2009
    ..Results of this study will help inform future research and potential preventive and therapeutic interventions against such chronic diseases...
  9. ncbi request reprint Effect of providing vitamin supplements to human immunodeficiency virus-infected, lactating mothers on the child's morbidity and CD4+ cell counts
    Wafaie W Fawzi
    Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts 02115, USA
    Clin Infect Dis 36:1053-62. 2003
    ..Provision of multivitamin supplements (including those with vitamins B, C, and E) to HIV-infected, lactating women may be a low-cost intervention to improve their children's health...
  10. ncbi request reprint Effect of maternal multivitamin supplementation on the mental and psychomotor development of children who are born to HIV-1-infected mothers in Tanzania
    Nuala McGrath
    Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
    Pediatrics 117:e216-25. 2006
    ....
  11. ncbi request reprint Micronutrients and human immunodeficiency virus type 1 disease progression among adults and children
    Wafaie Fawzi
    Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts 02115, USA
    Clin Infect Dis 37:S112-6. 2003
    ..For adults and children, more research is warranted on the role of selenium, zinc, and other trace elements on various measures of health among HIV-infected individuals...
  12. ncbi request reprint The timing of mother-to-child transmission of human immunodeficiency virus infection and the neurodevelopment of children in Tanzania
    Nuala McGrath
    Departments of Epidemiology, Harvard School of Public Health, Boston, MA, USA
    Pediatr Infect Dis J 25:47-52. 2006
    ..To determine the association between the timing of mother-to-child transmission of human immunodeficiency virus (HIV)-1 and neurodevelopment among children born to HIV-1 infected mothers in Tanzania...
  13. ncbi request reprint Trial of zinc supplements in relation to pregnancy outcomes, hematologic indicators, and T cell counts among HIV-1-infected women in Tanzania
    Wafaie W Fawzi
    Department of Nutrition, Muhimbili University, College of Health Sciences, Dar es Salaam, Tanzania
    Am J Clin Nutr 81:161-7. 2005
    ..In observational studies, the zinc status of HIV-infected persons has been associated with both positive and adverse clinical outcomes. Such endpoints may affect the risk of adverse birth outcomes among HIV-infected women...
  14. ncbi request reprint Vitamins and perinatal outcomes among HIV-negative women in Tanzania
    Wafaie W Fawzi
    Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
    N Engl J Med 356:1423-31. 2007
    ..Prematurity and low birth weight are associated with high perinatal and infant mortality, especially in developing countries. Maternal micronutrient deficiencies may contribute to these adverse outcomes...
  15. ncbi request reprint Multivitamin supplementation improves hematologic status in HIV-infected women and their children in Tanzania
    Wafaie W Fawzi
    Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
    Am J Clin Nutr 85:1335-43. 2007
    ..Anemia is a frequent complication among HIV-infected persons and is associated with faster disease progression and mortality...
  16. ncbi request reprint A randomized trial of multivitamin supplements and HIV disease progression and mortality
    Wafaie W Fawzi
    Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
    N Engl J Med 351:23-32. 2004
    ..Results from observational studies suggest that micronutrient status is a determinant of the progression of human immunodeficiency virus (HIV) disease...
  17. ncbi request reprint Effect of prenatal vitamin supplementation on lower-genital levels of HIV type 1 and interleukin type 1 beta at 36 weeks of gestation
    Wafaie Fawzi
    Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts 02115, USA
    Clin Infect Dis 38:716-22. 2004
    ....
  18. ncbi request reprint Maternal disease stage and child undernutrition in relation to mortality among children born to HIV-infected women in Tanzania
    Anirban Chatterjee
    Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
    J Acquir Immune Defic Syndr 46:599-606. 2007
    ..To examine whether maternal HIV disease stage during pregnancy and child malnutrition are associated with child mortality...
  19. ncbi request reprint A prospective study of malnutrition in relation to child mortality in the Sudan
    W W Fawzi
    Department of Nutrition and Epidemiology and Biostatistics, Harvard School of Public Health, Boston 02115, USA
    Am J Clin Nutr 65:1062-9. 1997
    ..Breast-feeding and reduction of morbidity should be advocated in programs designed to reduce malnutrition and mortality among children...
  20. ncbi request reprint Transmission of HIV-1 through breastfeeding among women in Dar es Salaam, Tanzania
    Wafaie Fawzi
    Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts 02115, USA
    J Acquir Immune Defic Syndr 31:331-8. 2002
    ..Transmission of HIV-1 through breastfeeding is a major problem, although its timing is not well characterized...
  21. ncbi request reprint Vitamin A supplementation and severity of pneumonia in children admitted to the hospital in Dar es Salaam, Tanzania
    W W Fawzi
    Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
    Am J Clin Nutr 68:187-92. 1998
    ..Large doses of vitamin A had no protective effect on the course of pneumonia in hospitalized Tanzanian children...
  22. ncbi request reprint A randomized trial of vitamin A supplements in relation to mortality among human immunodeficiency virus-infected and uninfected children in Tanzania
    W W Fawzi
    Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
    Pediatr Infect Dis J 18:127-33. 1999
    ..To determine whether vitamin A supplements result in reduced mortality among HIV-infected and uninfected children...
  23. ncbi request reprint A prospective study of age and lifestyle factors in relation to community-acquired pneumonia in US men and women
    I Baik
    Harvard School of Public Health, Department of Nutrition, 665 Huntington Ave, Bldg 2, Room 329, Boston, MA 02115, USA
    Arch Intern Med 160:3082-8. 2000
    ..We examined the associations of age, smoking status, body mass index (BMI), weight change during adulthood, physical activity, and alcohol intake with risk of CAP among men and women...
  24. ncbi request reprint Nutritional factors and vertical transmission of HIV-1. Epidemiology and potential mechanisms
    W Fawzi
    Departments of Nutrition and Epidemiology, Harvard School of Public Health, Boston, Massachusetts 02115, USA
    Ann N Y Acad Sci 918:99-114. 2000
    ..The potential benefits of direct supplementation of children born to HIV-infected women on transmission of HIV, as well as on the risk and severity of childhood infections and mortality, are also important to examine...
  25. ncbi request reprint Studies of vitamins and minerals and HIV transmission and disease progression
    Wafaie Fawzi
    Department of Nutrition, Harvard School of Public Health, Boston, MA, USA
    J Nutr 135:938-44. 2005
    ....
  26. ncbi request reprint Randomized trial of vitamin supplements in relation to transmission of HIV-1 through breastfeeding and early child mortality
    Wafaie W Fawzi
    Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
    AIDS 16:1935-44. 2002
    ..HIV-1 transmission through breastfeeding is a global problem and has been associated with poor maternal micronutrient status...
  27. ncbi request reprint Association between low birth weight and infant mortality in children born to human immunodeficiency virus 1-infected mothers in Tanzania
    Ruilan Wei
    Department of Nutrition, Harvard School of Public Health, Boston, MA, USA
    Pediatr Infect Dis J 23:530-5. 2004
    ..The relationship between low birth weight and infant mortality among children born to human immunodeficiency virus (HIV)-infected mothers has not been thoroughly investigated...
  28. ncbi request reprint Predictors of intrauterine and intrapartum transmission of HIV-1 among Tanzanian women
    W Fawzi
    Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
    AIDS 15:1157-65. 2001
    ..Whether sustained clearance of lower genital tract infections result in reduced transmission remains to be determined...
  29. ncbi request reprint A new human immunodeficiency virus type 1 circulating recombinant form from Tanzania
    I N Koulinska
    Harvard AIDS Institute and Department of Immunology and Infectious Diseases, Harvard School of Public Health, Boston, Massachusetts 02115, USA
    AIDS Res Hum Retroviruses 17:423-31. 2001
    ..Future surveys will be needed to determine the potential of this CRF for epidemic spread...
  30. ncbi request reprint Differences in perinatal transmission among human immunodeficiency virus type 1 genotypes
    B Renjifo
    Department of Immunology and Infectious Diseases, Harvard Medical School of Public Health, Boston, Massachusetts 02115 6017, USA
    J Hum Virol 4:16-25. 2001
    ..To determine whether genotypes from human immunodeficiency virus type 1 (HIV-1) subtypes A, C, or D or intersubtype recombinants have the same probability of being transmitted from mother to child...
  31. ncbi request reprint Breastfeeding and maternal HIV-1 disease progression and mortality
    Gilda Sedgh
    Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts 02115, USA
    AIDS 18:1043-9. 2004
    ..To examine the association between breastfeeding and disease progression among HIV-infected women in Dar es Salaam, Tanzania...
  32. ncbi request reprint Micronutrients and child health: studies in international nutrition and HIV infection
    C Duggan
    Department of Pediatrics, Harvard Medical School, Boston, MA 02115, USA
    Nutr Rev 59:358-69. 2001
    ..Vitamin A therapy has not been associated with improved growth, whereas some trials have shown that zinc supplementation is associated with greater increments in height. Further trials of micronutrient supplementation are warranted...
  33. pmc Vitamin supplementation increases risk of subclinical mastitis in HIV-infected women
    Joanne E Arsenault
    Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
    J Nutr 140:1788-92. 2010
    ..10). Supplementation of HIV-infected women with vitamins increased the risk of subclinical mastitis...
  34. ncbi request reprint HIV-1 LTR subtype and perinatal transmission
    J T Blackard
    Department of Immunology and Infectious Diseases, Harvard School of Public Health, Boston, Massachusetts 02115, USA
    Virology 287:261-5. 2001
    ..These differences in transmission were independent of maternal CD4 at enrollment. Thus, it appears that HIV-1 subtype may be associated with differing rates of perinatal transmission in Tanzania...
  35. ncbi request reprint Socio-economic and demographic factors associated with prevalence of HIV infection among pregnant women in Dar es Salaam, Tanzania
    G Msamanga
    Department of Community Health, Muhimbili University College of Health Sciences, P O Box 65015, Dar es Salaam, Tanzania
    East Afr Med J 83:311-21. 2006
    ..Global effort to scale-up pMTCT is underway, however, mechanisms to maximise screening of HIV- 1 positive women for Nevirapine treatment and other interventions, are not clear...
  36. ncbi request reprint Subclinical mastitis, cell-associated HIV-1 shedding in breast milk, and breast-feeding transmission of HIV-1
    Serpil Kantarci
    Department of Nutrition, Harvard School of Public Health, Boston, MA, USA
    J Acquir Immune Defic Syndr 46:651-4. 2007
    ..It is unclear whether this association is mediated by increased cell-free virus (CFV) versus cell-associated virus (CAV) HIV shedding in breast milk...
  37. ncbi request reprint Micronutrients and vertical transmission of HIV-1
    Michele L Dreyfuss
    Department of Nutrition, Harvard School of Public Health, Boston, USA
    Am J Clin Nutr 75:959-70. 2002
    ..However, the ability of prenatal and postpartum micronutrient supplements to reduce transmission during the breast-feeding period is still unknown...
  38. pmc Placental malaria and mother-to-child transmission of human immunodeficiency virus-1
    Gernard I Msamanga
    Department of Community Health, Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania
    Am J Trop Med Hyg 80:508-15. 2009
    ..08). In conclusion, PM was not associated with infant HIV-1 infection status at birth. The interaction of maternal plasma viral load, PM, and MTCT of HIV-1 warrants further studies...
  39. pmc Effect of prenatal and perinatal antibiotics on maternal health in Malawi, Tanzania, and Zambia
    Said Aboud
    Department of Microbiology and Immunology, Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania
    Int J Gynaecol Obstet 107:202-7. 2009
    ..We assessed the effect of prenatal and peripartum antibiotics on maternal morbidity and mortality among HIV-infected and uninfected women...
  40. ncbi request reprint Depressive symptoms increase risk of HIV disease progression and mortality among women in Tanzania
    Gretchen Antelman
    Department of Nutrition, Harvard School of Public Health, Boston, MA, USA
    J Acquir Immune Defic Syndr 44:470-7. 2007
    ..89 to 3.71]). Depression is common among HIV-infected Tanzanian women and increases the risk of disease progression. Screening for depression and providing psychosocial interventions should be considered part of comprehensive HIV care...
  41. pmc Elevated alanine aminotransferase in antiretroviral-naïve HIV-infected African patients: magnitude and risk factors
    T J Nagu
    Muhimbili University of Health and Allied Sciences MUHAS, Dar es Salaam, Tanzania
    HIV Med 13:541-8. 2012
    ..Elevations in ALT are predictive of increased mortality from liver disease and may influence the choice of first-line antiretroviral therapy (ART)...
  42. ncbi request reprint Malaria parasitaemia in relation to HIV status and vitamin A supplementation among pre-school children
    Eduardo Villamor
    Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
    Trop Med Int Health 8:1051-61. 2003
    ..To ascertain whether malaria parasitaemia in children is associated with HIV status. To examine the effect of vitamin A supplementation on malaria parasitaemia in children...
  43. ncbi request reprint Pattern and predictors of weight gain during pregnancy among HIV-1-infected women from Tanzania
    Eduardo Villamor
    Department of Nutrition, Harvard School of Public Health, 665 Huntington Avenue, Boston, MA 02115, U S A
    J Acquir Immune Defic Syndr 32:560-9. 2003
    ..Prevention and treatment of parasitic infections and improvement of nutritional status are likely to enhance the pattern of gestational weight gain among HIV-infected women...
  44. doi request reprint Zinc as an adjunct for childhood pneumonia - interpreting early results
    Uma Chandra Mouli Natchu
    Department of Nutrition, Harvard School of Public Health, Boston, Massachussets 02115, USA
    Nutr Rev 66:398-405. 2008
    ..Future studies are needed that are large enough to be sufficiently powered to accommodate larger treatment failure rates, an issue that ongoing trials will hopefully address...
  45. pmc Patterns of postnatal growth in HIV-infected and HIV-exposed children
    Sheila Isanaka
    Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts 02115, USA
    Nutr Rev 67:343-59. 2009
    ..Timely growth monitoring may be used to improve the clinical course and quality of life of these children...
  46. pmc Vitamin A and vitamin B-12 concentrations in relation to mortality and morbidity among children born to HIV-infected women
    Anirban Chatterjee
    Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
    J Trop Pediatr 56:27-35. 2010
    ..Higher vitamin A concentrations in plasma are protective against mortality in children born to HIV-infected women...
  47. pmc Effect of selenium supplements on hemoglobin concentration and morbidity among HIV-1-infected Tanzanian women
    Roland Kupka
    Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts, USA
    Clin Infect Dis 48:1475-8. 2009
    ..05 g/dL; 95% confidence interval, -0.07 to 0.16 g/dL) but reduced diarrheal morbidity risk by 40% (relative risk, 0.60; 95% confidence interval, 0.42-0.84). There was no effect on the other morbidity end points...
  48. ncbi request reprint Iron status is an important cause of anemia in HIV-infected Tanzanian women but is not related to accelerated HIV disease progression
    Roland Kupka
    Department of Nutrition, Harvard School of Public Health, Boston, MA 02125, USA
    J Nutr 137:2317-23. 2007
    ..High storage iron does not appear to be related to HIV disease progression in this population, but more research on the role of iron during HIV disease is needed...
  49. pmc Predictors of stillbirth among HIV-infected Tanzanian women
    Roland Kupka
    Department of Nutrition, Harvard School of Public Health, Boston, MA, USA
    Acta Obstet Gynecol Scand 88:584-92. 2009
    ..To determine maternal risk factors for stillbirth among pregnant HIV-infected women in sub-Saharan Africa...
  50. ncbi request reprint Geophagy (Soil-eating) in relation to Anemia and Helminth infection among HIV-infected pregnant women in Tanzania
    Kosuke Kawai
    Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
    Am J Trop Med Hyg 80:36-43. 2009
    ..16; 95% CI = 0.98-1.36) and a lower hemoglobin concentration (adjusted-mean difference -3.8 g/L; 95% CI [-7.3, -0.4]). Pregnant women should be informed about the potential risks associated with soil consumption...
  51. doi request reprint Parents' and teachers' communication about HIV and sex in relation to the timing of sexual initiation among young adolescents in Tanzania
    Kosuke Kawai
    Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
    Scand J Public Health 36:879-88. 2008
    ..Our study examines parents' and teachers' communication about sexual matters in relation to the timing of sexual initiation among students aged 12-14 years old in Dar es Salaam, Tanzania...
  52. ncbi request reprint Herpes simplex virus type 2 infection among bar and hotel workers in northern Tanzania: prevalence and risk factors
    Saidi H Kapiga
    Department of Population and International Health, Harvard School of Public Health, Boston, Massachusetts 02115, USA
    Sex Transm Dis 30:187-92. 2003
    ..Type-specific serological tests have allowed for a better understanding of the epidemiology of herpes simplex virus type 2 (HSV-2) infection in Africa...
  53. pmc Predictors and consequences of anaemia among antiretroviral-naïve HIV-infected and HIV-uninfected children in Tanzania
    Anirban Chatterjee
    Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
    Public Health Nutr 13:289-96. 2010
    ..The aims of the present study were to identify maternal and child predictors of anaemia among children born to HIV-infected women and to study the association between childhood anaemia and mortality...
  54. pmc Patterns and predictors of CD4 T-cell counts among children born to HIV-infected women in Tanzania
    Roland Kupka
    Department of Nutrition, Harvard School of Public Health, 665 Huntington Avenue, Boston, MA 02115, USA
    J Trop Pediatr 55:290-6. 2009
    ..5 g/dl among HIV-uninfected children. The maternal and child predictors described may serve as intervention targets among HIV-exposed children...
  55. ncbi request reprint Vitamin A supplements ameliorate the adverse effect of HIV-1, malaria, and diarrheal infections on child growth
    Eduardo Villamor
    Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA
    Pediatrics 109:E6. 2002
    ..We hypothesize that vitamin A supplementation could ameliorate the adverse effect of these infections on child growth...
  56. ncbi request reprint Correlates of plasma HIV-1 RNA viral load among HIV-1-seropositive women in Dar es Salaam, Tanzania
    Saidi H Kapiga
    Department of Population and International Health, Harvard School of Public Health, Boston, Massachusetts 02115, USA
    J Acquir Immune Defic Syndr 30:316-23. 2002
    ..007). Although the long-term effects of malaria on viral load are unknown, prevention of malaria among people living with HIV-1 should be given the highest priority...
  57. ncbi request reprint Effect of multivitamin and vitamin A supplements on weight gain during pregnancy among HIV-1-infected women
    Eduardo Villamor
    Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
    Am J Clin Nutr 76:1082-90. 2002
    ..Multivitamin supplementation was shown to be effective in preventing adverse pregnancy outcomes among HIV-positive women. These protective effects could be mediated in part by an improvement in the pattern of gestational weight gain...
  58. pmc Malaria parasitemia and CD4 T cell count, viral load, and adverse HIV outcomes among HIV-infected pregnant women in Tanzania
    Molly F Franke
    Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA
    Am J Trop Med Hyg 82:556-62. 2010
    ..1-6.0; P test for heterogeneity = 0.05). Further study is warranted to determine whether or not parasitemia is especially detrimental to individuals with lower levels of immunosuppression or chronic low parasitemia...
  59. pmc Sex differences in the effects of maternal vitamin supplements on mortality and morbidity among children born to HIV-infected women in Tanzania
    Kosuke Kawai
    Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
    Br J Nutr 103:1784-91. 2010
    ..More research is warranted to examine the effect of vitamins by sex and better understand biological mechanisms mediating such effects...
  60. pmc Vitamin D status of HIV-infected women and its association with HIV disease progression, anemia, and mortality
    Saurabh Mehta
    Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, United States of America
    PLoS ONE 5:e8770. 2010
    ....
  61. pmc Macronutrient supplementation and food prices in HIV treatment
    Kevin A Sztam
    Children s Hospital Boston, Division of Pediatric Gastroenterology and Nutrition, Boston, MA 02115, USA
    J Nutr 140:213S-23S. 2010
    ..HIV treatment programs may struggle to meet the needs of patients with potential increased rates of malnutrition and food insecurity in the setting of high food prices...
  62. pmc A randomized trial to determine the optimal dosage of multivitamin supplements to reduce adverse pregnancy outcomes among HIV-infected women in Tanzania
    Kosuke Kawai
    Department of Epidemiology, Harvard School of Public Health, 677 Huntington Avenue, Boston, MA 02115, USA
    Am J Clin Nutr 91:391-7. 2010
    ..The minimum dosage of multivitamins necessary for optimal benefits is unknown...
  63. ncbi request reprint Plasma zinc concentrations are depressed during the acute phase response in children with falciparum malaria
    Christopher Duggan
    Division of Gastroenterology and Nutrition, Children s Hospital, Boston, MA, USA
    J Nutr 135:802-7. 2005
    ..In children whose age, diet, and/or nutritional status place them at risk of zinc deficiency, those with low plasma zinc levels should be supplemented with oral zinc and followed for clinical and/or biochemical response...
  64. pmc Perinatal outcomes, including mother-to-child transmission of HIV, and child mortality and their association with maternal vitamin D status in Tanzania
    Saurabh Mehta
    Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts 02115, USA
    J Infect Dis 200:1022-30. 2009
    ..Vitamin D is a strong immunomodulator and may protect against adverse pregnancy outcomes, mother-to-child transmission (MTCT) of human immunodeficiency virus (HIV), and child mortality...
  65. pmc Randomized, double-blind, placebo-controlled trial of selenium supplements among HIV-infected pregnant women in Tanzania: effects on maternal and child outcomes
    Roland Kupka
    Department of Nutrition, Harvard School of Public Health, Boston, MA 02120, USA
    Am J Clin Nutr 87:1802-8. 2008
    ..In observational studies, adequate selenium status has been associated with better pregnancy outcomes and slowed HIV disease progression...
  66. pmc Nutritional indicators of adverse pregnancy outcomes and mother-to-child transmission of HIV among HIV-infected women
    Saurabh Mehta
    Department of Nutrition and Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
    Am J Clin Nutr 87:1639-49. 2008
    ..Poor nutrition may be associated with mother-to-child transmission (MTCT) of HIV and other adverse pregnancy outcomes...
  67. ncbi request reprint Multivitamin supplementation of HIV-positive women during pregnancy reduces hypertension
    Anwar T Merchant
    Population Health Research Institute and McMaster University, Hamilton ON, Canada
    J Nutr 135:1776-81. 2005
    ..12, 95% CI 1.04-1.19, P = 0.002). Taking multivitamins containing vitamins B, C, and E during pregnancy may be an inexpensive and effective strategy to improve the health of the mother and baby...
  68. ncbi request reprint Vitamin A serostatus and heterosexual transmission of HIV: case-control study in Tanzania and review of the evidence
    Eduardo Villamor
    Department of Nutrition, Harvard School of Public Health, Boston, 02115, USA
    Int J Vitam Nutr Res 76:81-5. 2006
    ..14, 95% C I = 0.54, 8.45). In light of these and previous results, we conclude that there is not enough evidence yet to suggest a causal association between vitamin A and heterosexual transmission...
  69. ncbi request reprint Trends in obesity, underweight, and wasting among women attending prenatal clinics in urban Tanzania, 1995-2004
    Eduardo Villamor
    Department of Nutrition, Muhimbili University College of Health Sciences, Dar es Salaam, Tanzania
    Am J Clin Nutr 83:1387-94. 2006
    ..Scarce data are available from population studies on the recent trends and current epidemiology of obesity in African settings...
  70. ncbi request reprint Child mortality in relation to HIV infection, nutritional status, and socio-economic background
    Eduardo Villamor
    Department of Nutrition, Harvard School of Public Health, 665 Huntington Avenue, Boston, MA 02115, USA
    Int J Epidemiol 34:61-8. 2005
    ....
  71. ncbi request reprint Wasting during pregnancy increases the risk of mother-to-child HIV-1 transmission
    Eduardo Villamor
    Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
    J Acquir Immune Defic Syndr 38:622-6. 2005
    ..To examine whether wasting during pregnancy, as measured by weight loss and low weight gain, is associated with increased mother-to-child transmission (MTCT) of HIV-1...
  72. ncbi request reprint Adverse perinatal outcomes of HIV-1-infected women in relation to malaria parasitemia in maternal and umbilical cord blood
    Eduardo Villamor
    Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts 02115, USA
    Am J Trop Med Hyg 73:694-7. 2005
    ..Cord blood parasitemia is a strong predictor of neonatal death. The potential effect of zinc supplementation on clinical malaria outcomes deserves future investigation...
  73. ncbi request reprint Vitamin supplements, socioeconomic status, and morbidity events as predictors of wasting in HIV-infected women from Tanzania
    Eduardo Villamor
    Department of Nutrition and Community Health, Muhimbili University College of Health Sciences, Dar es Salaam, Tanzania
    Am J Clin Nutr 82:857-65. 2005
    ..Vitamin supplements delay the disease progression, but their effect on wasting is not known. Data are lacking on the risk factors for wasting in African HIV-infected persons...
  74. ncbi request reprint Anemia is an independent predictor of mortality and immunologic progression of disease among women with HIV in Tanzania
    Megan E O'Brien
    Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
    J Acquir Immune Defic Syndr 40:219-25. 2005
    ..To examine the association of anemia with mortality and disease progression among a cohort of women with HIV in Dar es Salaam, Tanzania...
  75. pmc Effects of vitamin a supplementation on immune responses and correlation with clinical outcomes
    Eduardo Villamor
    Department of Nutrition, Harvard School of Public Health, 665 Huntington Ave, Boston, MA 02115, USA
    Clin Microbiol Rev 18:446-64. 2005
    ..Additional studies with these age groups are needed...
  76. ncbi request reprint Vitamin supplementation of HIV-infected women improves postnatal child growth
    Eduardo Villamor
    Department of Nutrition and Community Health, Muhimbili University College of Health Sciences, Dar es Salaam, Tanzania
    Am J Clin Nutr 81:880-8. 2005
    ..Linear growth retardation and wasting are common in children born to HIV-infected women. Inexpensive interventions that could improve the postnatal growth pattern of such children are needed...
  77. ncbi request reprint Selenium status is associated with accelerated HIV disease progression among HIV-1-infected pregnant women in Tanzania
    Roland Kupka
    Department of Nutrition, Harvard School of Public Health, Boston MA, USA
    J Nutr 134:2556-60. 2004
    ..Selenium status may be important for clinical outcomes related to HIV disease in sub-Saharan Africa...
  78. ncbi request reprint Weight loss during pregnancy is associated with adverse pregnancy outcomes among HIV-1 infected women
    Eduardo Villamor
    Department of Nutrition, Harvard School of Public Health, Boston, MA, USA
    J Nutr 134:1424-31. 2004
    ..We conclude that poor anthropometric status at the first prenatal visit and weight loss during pregnancy among HIV-1 infected women are strong risk factors for adverse pregnancy outcomes...
  79. ncbi request reprint Vitamin intake is not associated with community-acquired pneumonia in U.S. men
    Anwar T Merchant
    Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
    J Nutr 134:439-44. 2004
    ..58, 95% CI, 0.39-0.86, P-value test for trend = 0.01). Vitamin supplements are unlikely to reduce pneumonia risk in well-nourished, middle-aged and older men...
  80. pmc A trial of the effect of micronutrient supplementation on treatment outcome, T cell counts, morbidity, and mortality in adults with pulmonary tuberculosis
    Eduardo Villamor
    Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
    J Infect Dis 197:1499-505. 2008
    ..Tuberculosis (TB) often coincides with nutritional deficiencies. The effects of micronutrient supplementation on TB treatment outcomes, clinical complications, and mortality are uncertain...
  81. ncbi request reprint Interaction of estrogen therapy with calcium and vitamin D supplementation on colorectal cancer risk: reanalysis of Women's Health Initiative randomized trial
    Eric L Ding
    Department of Nutrition, Harvard School of Public Health, 655 Huntington Ave, Boston, MA 02115, USA
    Int J Cancer 122:1690-4. 2008
    ..Important biological mechanisms related to the key membrane receptor megalin and estrogen-dependent protein calbindin are discussed...
  82. ncbi request reprint Long-chain n-6 polyunsaturated fatty acids in breast milk decrease the risk of HIV transmission through breastfeeding
    Eduardo Villamor
    Department of Nutrition, Harvard School of Public Health, 665 Huntington Avenue, Boston, MA 02115, USA
    Am J Clin Nutr 86:682-9. 2007
    ..Breastfeeding accounts for a sizable proportion of infant HIV infections. Some fatty acids (FAs) are potent immunomodulators with virucidal activity, and their primary source in breastfed children is breast milk...
  83. ncbi request reprint Effects of maternal vitamin supplements on malaria in children born to HIV-infected women
    Eduardo Villamor
    Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts 02115, USA
    Am J Trop Med Hyg 76:1066-71. 2007
    ..Supplementation of pregnant and lactating HIV-infected women with vitamins B, C, and E might be a useful, inexpensive intervention to decrease the burden of malaria in children born to HIV-infected women in sub-Saharan Africa...
  84. ncbi request reprint HIV-1 infection and fertility in Dar es Salaam, Tanzania
    Gilda Sedgh
    Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA
    Afr J Reprod Health 10:41-52. 2006
    ..We conclude that HIV-1 infected women had higher pregnancy rates than uninfected women. This association disappeared when analyses were limited to women with advanced disease. Abstract word count: 150...
  85. ncbi request reprint Acceptance of HIV testing among pregnant women in Dar-es-Salaam, Tanzania
    Emily F Westheimer
    Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA
    J Acquir Immune Defic Syndr 37:1197-205. 2004
    ..This study assesses correlates of acceptance of testing for HIV infection in the antenatal setting in Dar-es-Salaam, Tanzania...
  86. ncbi request reprint Validity of the Hopkins Symptom Checklist-25 amongst HIV-positive pregnant women in Tanzania
    S F Kaaya
    Department of Psychiatry, Muhimbili University College of Health Sciences, Dar es Salaam, Tanzania
    Acta Psychiatr Scand 106:9-19. 2002
    ..To validate the Hopkins Symptom Checklist-25 (HSCL-25) for use as a depression screen amongst human immuno-deficiency virus (HIV) positive pregnant women...
  87. ncbi request reprint Intake of n-6 and n-3 fatty acids and fish and risk of community-acquired pneumonia in US men
    Anwar T Merchant
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada
    Am J Clin Nutr 82:668-74. 2005
    ..Essential fatty acids modulate inflammation and glucose metabolism and may alter infection risk...
  88. ncbi request reprint HIV-1 disease progression and fertility in Dar es Salaam, Tanzania
    Gilda Sedgh
    Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA
    J Acquir Immune Defic Syndr 39:439-45. 2005
    ..To examine the association of HIV-1 disease progression with pregnancy and live birth incidence in a cohort of HIV-1-positive women in Dar es Salaam, Tanzania, and to identify other determinants of fertility in this population...
  89. ncbi request reprint Micronutrients in HIV-positive persons receiving highly active antiretroviral therapy
    Paul K Drain
    University of Washington School of Medicine, Seattle, WA 98195, USA
    Am J Clin Nutr 85:333-45. 2007
    ....
  90. ncbi request reprint Triple trouble: the role of malnutrition in tuberculosis and human immunodeficiency virus co-infection
    Monique van Lettow
    Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
    Nutr Rev 61:81-90. 2003
    ..Further investigation is needed to evaluate the prophylactic and therapeutic potential of nutritional interventions for co-infection with HIV and tuberculosis...
  91. pmc C-reactive protein independently predicts HIV-related outcomes among women and children in a resource-poor setting
    Paul K Drain
    School of Medicine, University of Washington, Seattle, Washington, USA
    AIDS 21:2067-75. 2007
    ..To evaluate C-reactive protein (CRP) as a predictor of HIV-related outcomes among women and children in a resource-poor setting...
  92. ncbi request reprint The benefits and concerns related to vitamin a supplementation
    Wafaie W Fawzi
    J Infect Dis 193:756-9. 2006
  93. ncbi request reprint Calibration of a semi-quantitative food frequency questionnaire in early pregnancy
    Wafaie W Fawzi
    Department of Nutrition, Harvard School of Public Health and Harvard Pilgrim Health Care, Boston, MA
    Ann Epidemiol 14:754-62. 2004
    ..We assessed the validity of a semi-quantitative food frequency questionnaire (FFQ) among pregnant women...

Research Grants27

  1. TRIALS OF VITAMINS IN HIV PROGRESSION AND TRANSMISSION
    Wafaie Fawzi; Fiscal Year: 2000
    ..abstract_text> ..
  2. Partnership on Nutrition and HIV/AIDS Research in Tanza*
    Wafaie Fawzi; Fiscal Year: 2006
    ..The program will be carried out as a collaborative effort between Muhimbili University College of Health Sciences, Dar-es-Salaam, Tanzania and the Harvard School of Public Health, Boston, MA. ..
  3. Trial of Vitamins in HIV Progression and Transmission
    Wafaie Fawzi; Fiscal Year: 2006
    ..The study is a collaborative effort between Harvard School of Public Health and Muhimbili University College of Health Sciences, Dar-es-Salaam, Tanzania. ..
  4. Trial of Vitamins among Children of HIV-infected Mothers
    Wafaie Fawzi; Fiscal Year: 2007
    ..The study will be carried out as a collaborative effort between the Harvard School of Public Health and Muhimbili University College of Health Sciences, Dar-es-Salaam, Tanzania. ..
  5. Trial of Vitamins in HIV Progression and Transmission
    Wafaie Fawzi; Fiscal Year: 2007
    ..The study is a collaborative effort between Harvard School of Public Health and Muhimbili University College of Health Sciences, Dar-es-Salaam, Tanzania. ..
  6. Trial of Vitamins in HIV Progression and Transmission
    Wafaie Fawzi; Fiscal Year: 2009
    ..The study is a collaborative effort between Harvard School of Public Health and Muhimbili University College of Health Sciences, Dar-es-Salaam, Tanzania. ..
  7. Multi-vitamins, HAART and HIV/AIDS in Uganda
    Wafaie Fawzi; Fiscal Year: 2009
    ..In particular, multivitamins might confer important clinical benefits that would help preserve limited drug regimens in developing countries amidst increasing viral resistant HIV strains. ..
  8. Malaria in Pregnancy: Nutrition and Immunologic Effects
    Wafaie Fawzi; Fiscal Year: 2009
    ....
  9. Multi-vitamins, HAART and HIV/AIDS in Uganda
    Wafaie W Fawzi; Fiscal Year: 2010
    ..In particular, multivitamins might confer important clinical benefits that would help preserve limited drug regimens in developing countries amidst increasing viral resistant HIV strains. ..
  10. Harvard Tanzania HIV/AIDS Clinical Trials Unit
    Wafaie Fawzi; Fiscal Year: 2007
    ..administrative component ..
  11. Trial of Vitamins among Children of HIV-infected Mothers
    Wafaie Fawzi; Fiscal Year: 2006
    ..The study will be carried out as a collaborative effort between the Harvard School of Public Health and Muhimbili University College of Health Sciences, Dar-es-Salaam, Tanzania. ..
  12. Trial of Vitamins in HIV Progression and Transmission
    Wafaie Fawzi; Fiscal Year: 2005
    ..The study is a collaborative effort between Harvard School of Public Health and Muhimbili University College of Health Sciences, Dar-es-Salaam, Tanzania. ..
  13. A TRAIL OF MICRONUTRIENTS AND ADVERSE PREGNANCY OUTCOMES
    Wafaie Fawzi; Fiscal Year: 2000
    ..To examine potential mechanisms of action of the supplements or dietary patterns and intake of individual nutrients, they will assess the following secondary outcomes among women: hemoglobin levels, T cell counts, and placental weight. ..
  14. TRIALS OF VITAMINS IN HIV PROGRESSION AND TRANSMISSION
    Wafaie Fawzi; Fiscal Year: 2001
    ..abstract_text> ..
  15. A TRAIL OF MICRONUTRIENTS AND ADVERSE PREGNACY OUTCOMES
    Wafaie Fawzi; Fiscal Year: 2001
    ..To examine potential mechanisms of action of the supplements or dietary patterns and intake of individual nutrients, they will assess the following secondary outcomes among women: hemoglobin levels, T cell counts, and placental weight. ..
  16. A TRAIL OF MICRONUTRIENTS AND ADVERSE PREGNACY OUTCOMES
    Wafaie Fawzi; Fiscal Year: 2002
    ..To examine potential mechanisms of action of the supplements or dietary patterns and intake of individual nutrients, they will assess the following secondary outcomes among women: hemoglobin levels, T cell counts, and placental weight. ..
  17. TRIALS OF VITAMINS IN HIV PROGRESSION AND TRANSMISSION
    Wafaie Fawzi; Fiscal Year: 2002
    ..abstract_text> ..
  18. Trial of Vitamins among Children of HIV-infected Mothers
    Wafaie Fawzi; Fiscal Year: 2003
    ..The study will be carried out as a collaborative effort between the Harvard School of Public Health and Muhimbili University College of Health Sciences, Dar-es-Salaam, Tanzania. ..
  19. A TRAIL OF MICRONUTRIENTS AND ADVERSE PREGNACY OUTCOMES
    Wafaie Fawzi; Fiscal Year: 2003
    ..To examine potential mechanisms of action of the supplements or dietary patterns and intake of individual nutrients, they will assess the following secondary outcomes among women: hemoglobin levels, T cell counts, and placental weight. ..
  20. Trial of Vitamins among Children of HIV-infected Mothers
    Wafaie Fawzi; Fiscal Year: 2004
    ..The study will be carried out as a collaborative effort between the Harvard School of Public Health and Muhimbili University College of Health Sciences, Dar-es-Salaam, Tanzania. ..
  21. HIV PREVENTION TRIALS UNIT
    Wafaie Fawzi; Fiscal Year: 2004
    ..S., the commitment of the authorities in Tanzania to HIV research, and the political stability in Tanzania, would make this collaboration a valuable addition to the HPTN. ..
  22. Trial of Vitamins among Children of HIV-infected Mothers
    Wafaie Fawzi; Fiscal Year: 2005
    ..The study will be carried out as a collaborative effort between the Harvard School of Public Health and Muhimbili University College of Health Sciences, Dar-es-Salaam, Tanzania. ..
  23. NUTRITION, IMMUNOLOGY, AND EPIDEMIOLOGY OF TB
    Wafaie Fawzi; Fiscal Year: 2004
    ..abstract_text> ..
  24. Malaria in Pregnancy: Nutrition and Immunologic Effects
    Wafaie W Fawzi; Fiscal Year: 2010
    ....