Research Topics
| W B FarquharSummaryAffiliation: Harvard University Country: USA Publications
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Detail Information
Publications
Age and renal prostaglandin inhibition during exercise and heat stressW B Farquhar
Noll Physiological Research Center, Pennsylvania State University, University Park, Pennsylvania 16802 6900, USA
J Appl Physiol 86:1936-43. 1999..We conclude that PG inhibition has only modest effects on renal function during exercise. Also, the lack of hemodynamic changes with PG inhibition indicates that healthy well-hydrated older women are not in a renal PG-dependent state...
Effects of creatine use on the athlete's kidneyWilliam B Farquhar
HRCA Research and Training Institute, Harvard Division on Aging, 1200 Centre Street, Boston, MA 02131, USA
Curr Sports Med Rep 1:103-6. 2002..More information is needed on possible changes in blood pressure, protein/albumin excretion, and glomerular filtration in athletes who are habitual users of this compound...
Quantification of mechanical and neural components of vagal baroreflex in humansB E Hunt
Laboratory for Cardiovascular Research, Hebrew Rehabilitation Center for Aged Research and Training Institute, Boston, MA 02131, USA
Hypertension 37:1362-8. 2001..93, P=0.001). This technique provides reliable information on key baroreflex components not distinguished by standard assessments and gives insight to dynamic mechanical and neural events during acute changes in arterial pressure...
Does reduced vascular stiffening fully explain preserved cardiovagal baroreflex function in older, physically active men?B E Hunt
Laboratory for Cardiovascular Research, Research and Training Institute, Hebrew Rehabilitation Center for Aged, Boston, MA 02131, USA
Circulation 103:2424-7. 2001..We measured cardiovagal baroreflex gain and its vascular mechanical and neural components during dynamic baroreflex engagement in 10 young untrained men, 6 older untrained men, and 12 older, physically active men...
Ultrasound assessment of popliteal vein compliance during a short deflation protocolColin N Young
Department of Health, Nutrition, and Exercise Sciences, 142 Human Performance Laboratory, University of Delaware, 541 South College Avenue, Newark, DE 19716, USA
J Appl Physiol 104:1374-80. 2008..Additionally, popliteal vein and calf compliance were not affected by the CP test or NTG...
Influence of plasma osmolality on baroreflex control of sympathetic activityMegan M Wenner
Department of Health, Nutrition, College of Health Sciences, University of Delaware, Delaware 19716, USA
Am J Physiol Heart Circ Physiol 293:H2313-9. 2007..ISO: -4.0 +/- 0.8 arbitrary units x beat(-1) x mmHg(-1), P = 0.01). In conclusion, when controlling for intravascular volume, increased plasma osmolality enhances baroreflex control of sympathetic activity in humans...
Venous smooth muscle tone and responsiveness in older adultsColin N Young
Department of Health, Nutrition, and Exercise Sciences, University of Delaware, Newark, USA
J Appl Physiol 101:1362-7. 2006..Data suggest that forearm and calf venous compliance is lower in older adults compared with young. However, this difference probably cannot be explained by alterations in smooth muscle tone or responsiveness...
Limb venous tone and responsiveness in hypertensive humansErin P Delaney
Department of Health, Nutrition and Exercise Sciences, University of Delaware, Newark, DE 19716, USA
J Appl Physiol 105:894-901. 2008..These data suggest that young HTN adults may have augmented venous smooth muscle tone compared with NTN controls...
Limb venous compliance in patients with idiopathic orthostatic intolerance and postural tachycardiaRoy Freeman
Center for Autonomic and Peripheral Nerve Disorders, Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts 02215, USA
J Appl Physiol 93:636-44. 2002..Reduced compliance may limit the dynamic response to orthostatic change and thereby contribute to symptoms of orthostatic intolerance in this population group...
Blood volume and its relation to peak O(2) consumption and physical activity in patients with chronic fatigueWilliam B Farquhar
Center for Autonomic and Peripheral Nerve Disorders, Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA
Am J Physiol Heart Circ Physiol 282:H66-71. 2002..These variables were highly related in both subject groups, indicating that blood volume is a strong physiological correlate of peak oxygen consumption in patients with CFS...
Blood pressure and hemodynamic responses to an acute sodium load in humansWilliam B Farquhar
Department of Health, Nutrition, and Exercise Sciences, University of Delaware, Newark, USA
J Appl Physiol 99:1545-51. 2005..In conclusion, an acute infusion of hypertonic saline was effective in increasing BP, and both sodium and volume appear to be involved in this increase; acute BP responsiveness to serum sodium can be quantified using a MAP-sodium plot...
Preserved autonomic function in amenorrheic athletesMegan M Wenner
Department of Health, Nutrition, and Excercise Sciences, University of Delaware, Newark, DE 19716, USA
J Appl Physiol 101:590-7. 2006..In conclusion, AA do not display signs of impaired autonomic function and orthostatic responses compared with EA or EA-OC during the follicular phase of the menstrual cycle...
Sympathetic neural responses to increased osmolality in humansWilliam B Farquhar
Department of Health, Nutrition, and Excercise Science, University of Delaware, USA
Am J Physiol Heart Circ Physiol 291:H2181-6. 2006..ISO: 202 +/- 49 pg/ml; ANOVA, P < 0.05). We conclude that HSI-induced increases in plasma osmolality are associated with increases in sympathetic activity in humans...
Carotid distensibility characterized via the isometric exercise pressor responseChristopher W Myers
Laboratory for Cardiovascular Research, Hebrew Rehabilitation Center for Aged, Boston, Massachusetts 02131, USA
Am J Physiol Heart Circ Physiol 283:H2592-8. 2002..Our results indicate that gender- and age-related differences can be manifest even in young, healthy adults and may only be identified with techniques that assess carotid distensibility across a range of pressures...
American College of Sports Medicine position stand. Exercise and hypertensionLinda S Pescatello
Med Sci Sports Exerc 36:533-53. 2004..Intensity: moderate-intensity (40-<60% VO2R). Time: > or = 30 min of continuous or accumulated physical activity per day. Type: primarily endurance physical activity supplemented by resistance exercise...
