Xiao Fang

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. ncbi request reprint Identification of selective inhibitors for the glycosyltransferase MurG via high-throughput screening
    Yanan Hu
    Department of Chemistry, Princeton University, Princeton, NJ 08544, USA
    Chem Biol 11:703-11. 2004
  2. ncbi request reprint The mechanism of action of ramoplanin and enduracidin
    Xiao Fang
    Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA 02128, USA
    Mol Biosyst 2:69-76. 2006
  3. pmc Functional and biochemical analysis of a key series of ramoplanin analogues
    Xiao Fang
    Department of Chemistry and Chemical Biology, Harvard University, 12 Oxford Street, Cambridge, MA 02138, USA
    Bioorg Med Chem Lett 19:6189-91. 2009
  4. pmc Imaging peptidoglycan biosynthesis in Bacillus subtilis with fluorescent antibiotics
    Kittichoat Tiyanont
    Department of Microbiology and Molecular Genetics, Harvard Medical School, Boston, MA 02115, USA
    Proc Natl Acad Sci U S A 103:11033-8. 2006

Collaborators

  • SUZANNE L WALKER
  • Dale Boger
  • Yi Zhang
  • Kittichoat Tiyanont
  • Yanan Hu
  • David Z Rudner
  • Michael B Lazarus
  • Thierry Doan
  • Lan Chen
  • Jeremiah S Helm
  • Tao Wu
  • Benjamin Gross
  • Cindy Ginsberg
  • Brian Kraybill

Detail Information

Publications4

  1. ncbi request reprint Identification of selective inhibitors for the glycosyltransferase MurG via high-throughput screening
    Yanan Hu
    Department of Chemistry, Princeton University, Princeton, NJ 08544, USA
    Chem Biol 11:703-11. 2004
    ..The donor displacement assay described here should be adaptable to many other NDP-Gtfs and represents a new strategy to identify selective NDP-Gtf inhibitors...
  2. ncbi request reprint The mechanism of action of ramoplanin and enduracidin
    Xiao Fang
    Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA 02128, USA
    Mol Biosyst 2:69-76. 2006
    ..These results provide compelling evidence that ramoplanin's and enduracidin's primary cellular target is the transglycosylation step of peptidoglycan biosynthesis...
  3. pmc Functional and biochemical analysis of a key series of ramoplanin analogues
    Xiao Fang
    Department of Chemistry and Chemical Biology, Harvard University, 12 Oxford Street, Cambridge, MA 02138, USA
    Bioorg Med Chem Lett 19:6189-91. 2009
    ....
  4. pmc Imaging peptidoglycan biosynthesis in Bacillus subtilis with fluorescent antibiotics
    Kittichoat Tiyanont
    Department of Microbiology and Molecular Genetics, Harvard Medical School, Boston, MA 02115, USA
    Proc Natl Acad Sci U S A 103:11033-8. 2006
    ..Although Mbl plays an important role in cell shape determination, our data indicate that other proteins control the spatial localization of the biosynthetic complexes responsible for new PG synthesis along the walls of B. subtilis cells...