Kevin M Esvelt

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. pmc Genome-scale engineering for systems and synthetic biology
    Kevin M Esvelt
    Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA 02115, USA
    Mol Syst Biol 9:641. 2013
  2. pmc Cas9 as a versatile tool for engineering biology
    Prashant Mali
    Department of Genetics, Harvard Medical School, Boston, Massachusetts, USA
    Nat Methods 10:957-63. 2013
  3. pmc CRISPR/Cas9-Mediated Phage Resistance Is Not Impeded by the DNA Modifications of Phage T4
    Stephanie J Yaung
    Wyss Institute for Biologically Inspired Engineering, Harvard Medical School, Boston, Massachusetts, United States of America Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America Program in Medical Engineering and Medical Physics, Harvard MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America
    PLoS ONE 9:e98811. 2014
  4. pmc Heritable genome editing in C. elegans via a CRISPR-Cas9 system
    Ari E Friedland
    Department of Genetics, Harvard Medical School, Boston, Massachusetts, USA
    Nat Methods 10:741-3. 2013

Collaborators

Detail Information

Publications4

  1. pmc Genome-scale engineering for systems and synthetic biology
    Kevin M Esvelt
    Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA 02115, USA
    Mol Syst Biol 9:641. 2013
    ....
  2. pmc Cas9 as a versatile tool for engineering biology
    Prashant Mali
    Department of Genetics, Harvard Medical School, Boston, Massachusetts, USA
    Nat Methods 10:957-63. 2013
    ..Here we describe the Cas9 targeting methodology, detail current and prospective engineering advances and suggest potential applications ranging from basic science to the clinic. ..
  3. pmc CRISPR/Cas9-Mediated Phage Resistance Is Not Impeded by the DNA Modifications of Phage T4
    Stephanie J Yaung
    Wyss Institute for Biologically Inspired Engineering, Harvard Medical School, Boston, Massachusetts, United States of America Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America Program in Medical Engineering and Medical Physics, Harvard MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America
    PLoS ONE 9:e98811. 2014
    ..Our results demonstrate that Cas9 is not impeded by N6-methyladenine, 5-methylcytosine, 5-hydroxymethylated cytosine, or glucosylated 5-hydroxymethylated cytosine. ..
  4. pmc Heritable genome editing in C. elegans via a CRISPR-Cas9 system
    Ari E Friedland
    Department of Genetics, Harvard Medical School, Boston, Massachusetts, USA
    Nat Methods 10:741-3. 2013
    ..Our results demonstrate that targeted, heritable genetic alterations can be achieved in C. elegans, providing a convenient and effective approach for generating loss-of-function mutants. ..