A Heather Eliassen

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. ncbi request reprint Endogenous hormone levels and risk of breast, endometrial and ovarian cancers: prospective studies
    A Heather Eliassen
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, Boston, MA 02115, USA
    Adv Exp Med Biol 630:148-65. 2008
  2. pmc Plasma carotenoids and risk of breast cancer over 20 y of follow-up
    A Heather Eliassen
    From the Channing Division of Network Medicine, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA AHE, XL, BR, RMT, SST, and SEH the Departments of Epidemiology AHE, XL, BR, RMT, SST, and SEH and Biostatistics XL and BR, Harvard T H Chan School of Public Health, Boston, MA and the Division of Biostatistics and Epidemiology, School of Public Health and Health Sciences, University of Massachusetts, Amherst, MA SEH
    Am J Clin Nutr 101:1197-205. 2015
  3. pmc Food predictors of plasma carotenoids
    Sara J Hendrickson
    Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
    Nutrients 5:4051-66. 2013
  4. pmc Circulating carotenoids and risk of breast cancer: pooled analysis of eight prospective studies
    A Heather Eliassen
    Channing Division of Network Medicine, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, 181 Longwood Ave, Boston, MA 02115, USA
    J Natl Cancer Inst 104:1905-16. 2012
  5. pmc Urinary estrogens and estrogen metabolites and subsequent risk of breast cancer among premenopausal women
    A Heather Eliassen
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA
    Cancer Res 72:696-706. 2012
  6. pmc Use of aspirin, other nonsteroidal anti-inflammatory drugs, and acetaminophen and risk of breast cancer among premenopausal women in the Nurses' Health Study II
    A Heather Eliassen
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, 181 Longwood Ave, Boston, MA 02115, USA
    Arch Intern Med 169:115-21; discussion 121. 2009
  7. pmc Reproducibility of fifteen urinary estrogens and estrogen metabolites over a 2- to 3-year period in premenopausal women
    A Heather Eliassen
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
    Cancer Epidemiol Biomarkers Prev 18:2860-8. 2009
  8. pmc Physical activity and risk of breast cancer among postmenopausal women
    A Heather Eliassen
    Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    Arch Intern Med 170:1758-64. 2010
  9. pmc Plasma 25-hydroxyvitamin D and risk of breast cancer in the Nurses' Health Study II
    A Heather Eliassen
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, Boston, MA 02115, USA
    Breast Cancer Res 13:R50. 2011
  10. ncbi request reprint Adult weight change and risk of postmenopausal breast cancer
    A Heather Eliassen
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, Mass 02115, USA
    JAMA 296:193-201. 2006

Detail Information

Publications77

  1. ncbi request reprint Endogenous hormone levels and risk of breast, endometrial and ovarian cancers: prospective studies
    A Heather Eliassen
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, Boston, MA 02115, USA
    Adv Exp Med Biol 630:148-65. 2008
    ..Clearly more evaluation is needed to confirm the role of endogenous hormones in premenopausal breast cancer, endometrial cancer and ovarian cancer...
  2. pmc Plasma carotenoids and risk of breast cancer over 20 y of follow-up
    A Heather Eliassen
    From the Channing Division of Network Medicine, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA AHE, XL, BR, RMT, SST, and SEH the Departments of Epidemiology AHE, XL, BR, RMT, SST, and SEH and Biostatistics XL and BR, Harvard T H Chan School of Public Health, Boston, MA and the Division of Biostatistics and Epidemiology, School of Public Health and Health Sciences, University of Massachusetts, Amherst, MA SEH
    Am J Clin Nutr 101:1197-205. 2015
    ..Whether carotenoids are important early or late in carcinogenesis is unclear, and limited analyses have been conducted by breast tumor subtypes...
  3. pmc Food predictors of plasma carotenoids
    Sara J Hendrickson
    Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
    Nutrients 5:4051-66. 2013
    ..28 and 0.31 for lutein/zeaxanthin, 0.22 and 0.23 for lycopene, and 0.22 and 0.27 for total carotenoids. Empirical prediction models may modestly improve assessment of some carotenoids, particularly α-carotene and β-cryptoxanthin. ..
  4. pmc Circulating carotenoids and risk of breast cancer: pooled analysis of eight prospective studies
    A Heather Eliassen
    Channing Division of Network Medicine, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, 181 Longwood Ave, Boston, MA 02115, USA
    J Natl Cancer Inst 104:1905-16. 2012
    ..Most, but not all, past studies of circulating carotenoids and breast cancer have found an inverse association with at least one carotenoid, although the specific carotenoid has varied across studies...
  5. pmc Urinary estrogens and estrogen metabolites and subsequent risk of breast cancer among premenopausal women
    A Heather Eliassen
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA
    Cancer Res 72:696-706. 2012
    ..The inverse associations with parent estrogen metabolites and the parent estrogen metabolite/non-parent estrogen metabolite ratio suggest that women with higher urinary excretion of parent estrogens are at lower risk...
  6. pmc Use of aspirin, other nonsteroidal anti-inflammatory drugs, and acetaminophen and risk of breast cancer among premenopausal women in the Nurses' Health Study II
    A Heather Eliassen
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, 181 Longwood Ave, Boston, MA 02115, USA
    Arch Intern Med 169:115-21; discussion 121. 2009
    ..In addition, the chemopreventive use of NSAIDs is increasingly common for heart disease and colon cancer. Evidence of a protective association with breast cancer risk has been inconsistent, and few data exist for premenopausal women...
  7. pmc Reproducibility of fifteen urinary estrogens and estrogen metabolites over a 2- to 3-year period in premenopausal women
    A Heather Eliassen
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
    Cancer Epidemiol Biomarkers Prev 18:2860-8. 2009
    ..Within-person reproducibility over time for most EM measures is comparable to or better than that for well-vetted biomarkers such as plasma cholesterol and, in postmenopausal women, estradiol...
  8. pmc Physical activity and risk of breast cancer among postmenopausal women
    A Heather Eliassen
    Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    Arch Intern Med 170:1758-64. 2010
    ..Although greater activity has been related to lower postmenopausal breast cancer risk, important details remain unclear, including type, intensity, and timing of activity and whether the association varies by subgroups...
  9. pmc Plasma 25-hydroxyvitamin D and risk of breast cancer in the Nurses' Health Study II
    A Heather Eliassen
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, Boston, MA 02115, USA
    Breast Cancer Res 13:R50. 2011
    ..Vitamin D comes from dietary intake and sun exposure and plasma levels of 25-hydroxyvitamin D (25(OH)D) are considered the best measure of vitamin D status...
  10. ncbi request reprint Adult weight change and risk of postmenopausal breast cancer
    A Heather Eliassen
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, Mass 02115, USA
    JAMA 296:193-201. 2006
    ..Endogenous hormones are a primary cause of breast cancer. Adiposity affects circulating hormones, particularly in postmenopausal women, and may be a modifiable risk factor for breast cancer...
  11. ncbi request reprint Circulating insulin and c-peptide levels and risk of breast cancer among predominately premenopausal women
    A Heather Eliassen
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, 181 Longwood Avenue, Boston, MA 02115, USA
    Cancer Epidemiol Biomarkers Prev 16:161-4. 2007
    ..These associations did not differ by age, body mass index, or waist-to-hip ratio. Overall, higher levels of insulin and c-peptide were not associated with a higher risk of breast cancer among predominantly premenopausal women...
  12. pmc Biomarker validation of dietary intervention in two multiethnic populations
    A Heather Eliassen
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, 181 Longwood Ave, Boston, MA 02115, USA
    Prev Chronic Dis 3:A44. 2006
    ..The Healthy Directions intervention studies were designed to increase multivitamin use, fruit and vegetable consumption, and physical activity in working-class, multiethnic populations...
  13. ncbi request reprint Reproductive factors and family history of breast cancer in relation to plasma prolactin levels in premenopausal and postmenopausal women
    A Heather Eliassen
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
    Int J Cancer 120:1536-41. 2007
    ..9 ng/mL vs. 14.3 ng/mL, p=0.04) but not postmenopausal (p=0.73) women. In conclusion, the associations of parity and family history with breast cancer risk may be mediated, at least in part, by prolactin levels...
  14. ncbi request reprint Endogenous steroid hormone concentrations and risk of breast cancer: does the association vary by a woman's predicted breast cancer risk?
    A Heather Eliassen
    Channing Laboratory, Brigham and Women s Hospital, Boston, MA 02115, USA
    J Clin Oncol 24:1823-30. 2006
    ....
  15. ncbi request reprint Endogenous steroid hormone concentrations and risk of breast cancer among premenopausal women
    A Heather Eliassen
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, 181 Longwood Ave, Boston, MA 02115, USA
    J Natl Cancer Inst 98:1406-15. 2006
    ..We prospectively evaluated associations between plasma sex hormone levels and breast cancer risk among premenopausal women in a case-control study nested within the Nurses' Health Study II...
  16. ncbi request reprint Serum lipids, lipid-lowering drugs, and the risk of breast cancer
    A Heather Eliassen
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, Mass 02115, USA
    Arch Intern Med 165:2264-71. 2005
    ..The relation between serum cholesterol levels and breast cancer risk is itself unclear; because cholesterol is the precursor to sex steroid hormones, higher levels could plausibly increase risk...
  17. ncbi request reprint Tubal sterilization in relation to breast cancer risk
    A Heather Eliassen
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
    Int J Cancer 118:2026-30. 2006
    ....
  18. pmc Circulating 2-hydroxy- and 16alpha-hydroxy estrone levels and risk of breast cancer among postmenopausal women
    A Heather Eliassen
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, 181 Longwood Avenue, Boston, MA 02115, USA
    Cancer Epidemiol Biomarkers Prev 17:2029-35. 2008
    ..The significant positive associations with 2-OH estrone and the 2-OH:16-OH estrone ratio among women with ER-negative/PR-negative tumors needs to be replicated in future studies...
  19. pmc Plasma enterolactone and breast cancer risk in the Nurses' Health Study II
    Jing Xie
    Channing Division of Network Medicine, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, 181 Longwood Avenue, Boston, MA 02115, USA
    Breast Cancer Res Treat 139:801-9. 2013
    ..This should be confirmed in future studies. ..
  20. ncbi request reprint Endogenous estrogen, androgen, and progesterone concentrations and breast cancer risk among postmenopausal women
    Stacey A Missmer
    Channing Laboratory, Brigham and Women s Hospital and Harvard Medical School, 181 Longwood Avenue, Boston, MA 02115, USA
    J Natl Cancer Inst 96:1856-65. 2004
    ..Nor has the relation between breast cancer risk and postmenopausal progesterone levels been investigated. We prospectively investigated these relations in a case-control study nested within the Nurses' Health Study...
  21. pmc The association of plasma androgen levels with breast, ovarian and endometrial cancer risk factors among postmenopausal women
    Kim N Danforth
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
    Int J Cancer 126:199-207. 2010
    ..Future studies are needed to clarify further which lifestyle factors modulate androgen levels...
  22. ncbi request reprint Physical activity and inactivity in relation to sex hormone, prolactin, and insulin-like growth factor concentrations in premenopausal women - exercise and premenopausal hormones
    Shelley S Tworoger
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, 181 Longwood Ave, 3rd Floor, Boston, MA 02115, USA
    Cancer Causes Control 18:743-52. 2007
    ..These cross-sectional results suggest that physical activity and inactivity have limited associations with premenopausal sex hormone and growth factor levels, except possibly luteal estrogens...
  23. pmc Analgesic use in relation to sex hormone and prolactin concentrations in premenopausal women
    Scott R Bauer
    Channing Division of Network Medicine, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, 181 Longwood Ave, 3rd Floor, Boston, MA 02115, USA
    Cancer Causes Control 24:1087-97. 2013
    ..Common analgesics (aspirin, non-aspirin NSAIDs, and acetaminophen) may be associated with hormone-related cancers, possibly via effects on sex hormone and prolactin concentrations...
  24. pmc Reproducibility of plasma and urine biomarkers among premenopausal and postmenopausal women from the Nurses' Health Studies
    Joanne Kotsopoulos
    Channing Laboratory, 181 Longwood Avenue, Boston, MA 02115, USA
    Cancer Epidemiol Biomarkers Prev 19:938-46. 2010
    ..Temporal variability of biomarkers should be evaluated before their use in epidemiologic studies...
  25. ncbi request reprint A prospective study of plasma prolactin concentrations and risk of premenopausal and postmenopausal breast cancer
    Shelley S Tworoger
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
    J Clin Oncol 25:1482-8. 2007
    ....
  26. pmc Analgesic use and sex steroid hormone concentrations in postmenopausal women
    Margaret A Gates
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
    Cancer Epidemiol Biomarkers Prev 19:1033-41. 2010
    ..04). Among postmenopausal women, regular users of aspirin and other analgesics may have lower estrogen levels than nonusers, which could contribute to a decreased risk of breast or ovarian cancer among analgesic users...
  27. ncbi request reprint The association of plasma DHEA and DHEA sulfate with breast cancer risk in predominantly premenopausal women
    Shelley S Tworoger
    Channing Laboratory, 181 Longwood Avenue, 3rd Floor, Boston, MA 02115, USA
    Cancer Epidemiol Biomarkers Prev 15:967-71. 2006
    ....
  28. ncbi request reprint Body shape throughout life and correlations with IGFs and GH
    Eva S Schernhammer
    Channing Laboratory, Department of Medicine, Harvard Medical School, Brigham and Women s Hospital, 181 Longwood Avenue, Boston 02115, Massachusetts, USA
    Endocr Relat Cancer 14:721-32. 2007
    ..Our results suggest that childhood and adult body size may affect premenopausal breast cancer risk differently than birth weight, through associations with IGF and GH levels...
  29. pmc Body size in relation to urinary estrogens and estrogen metabolites (EM) among premenopausal women during the luteal phase
    Jing Xie
    Channing Division of Network Medicine, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, 181 Longwood Avenue, Boston, MA 02115, USA
    Horm Cancer 3:249-60. 2012
    ..Our results suggest that height and current BMI are associated with estrogen metabolism profiles in premenopausal women. Further studies with timed urine and blood collections are required to confirm and extend our findings...
  30. pmc β-Carotene 15,15'-monooxygenase 1 single nucleotide polymorphisms in relation to plasma carotenoid and retinol concentrations in women of European descent
    Sara J Hendrickson
    Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA
    Am J Clin Nutr 96:1379-89. 2012
    ....
  31. ncbi request reprint Birthweight and body size throughout life in relation to sex hormones and prolactin concentrations in premenopausal women
    Shelley S Tworoger
    Channing Laboratory, 181 Longwood Avenue, 3rd Floor, Boston, MA 02115, USA
    Cancer Epidemiol Biomarkers Prev 15:2494-501. 2006
    ..Our results suggest that effects on premenopausal sex hormone levels may be one mechanism through which adult adiposity, but not birthweight or childhood body size, affects premenopausal breast cancer risk...
  32. pmc Relationship between caffeine intake and plasma sex hormone concentrations in premenopausal and postmenopausal women
    Joanne Kotsopoulos
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA
    Cancer 115:2765-74. 2009
    ..Caffeine intake may decrease risk of breast and ovarian cancer, although the data are not entirely consistent. Whether or not caffeine affects cancer risk by altering sex hormone levels is currently unknown...
  33. pmc Inclusion of endogenous hormone levels in risk prediction models of postmenopausal breast cancer
    Shelley S Tworoger
    Shelley S Tworoger, Xuehong Zhang, A Heather Eliassen, Walter C Willett, Bernard A Rosner, and Susan E Hankinson, Brigham and Women s Hospital and Harvard Medical School Shelley S Tworoger, Xuehong Zhang, A Heather Eliassen, Walter C Willett, Bernard A Rosner, Peter Kraft, and Susan E Hankinson, Harvard School of Public Health, Boston Jing Qian and Susan E Hankinson, School of Public Health and Health Sciences, University of Massachusetts, Amherst, MA and Graham A Colditz, Washington University School of Medicine, St Louis, MO
    J Clin Oncol 32:3111-7. 2014
    ....
  34. pmc Urinary estrogens and estrogen metabolites and mammographic density in premenopausal women
    Kimberly A Bertrand
    Department of Epidemiology, Harvard School of Public Health, 677 Huntington Avenue, Boston, MA 02115, USA
    Breast Cancer Res Treat 136:277-87. 2012
    ..If these profiles are associated with breast cancer risk, they may not act through influences on breast density...
  35. pmc Associations between red meat intake and biomarkers of inflammation and glucose metabolism in women
    Sylvia H Ley
    Departments of Nutrition SHL, QS, WCW, KW, AP, and FBH and Epidemiology WCW, FG, and FBH, Harvard School of Public Health, and the Channing Division of Network Medicine, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School QS, WCW, AHE, FG, and FBH, Boston, MA and the Saw Swee Hock School of Public Health and Yong Loo Lin School of Medicine, National University of Singapore and National University Health System, Singapore AP
    Am J Clin Nutr 99:352-60. 2014
    ..Greater red meat intake is associated with an increased type 2 diabetes and cardiovascular disease risk. However, the relation of red meat intake to biomarkers of inflammation and glucose metabolism has not been investigated thoroughly...
  36. pmc Plasma carotenoid- and retinol-weighted multi-SNP scores and risk of breast cancer in the National Cancer Institute Breast and Prostate Cancer Cohort Consortium
    Sara J Hendrickson
    Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
    Cancer Epidemiol Biomarkers Prev 22:927-36. 2013
    ..We determined associations between variants in BCMO1 and breast cancer risk in a large cohort consortium...
  37. pmc Adult weight change and incidence of premenopausal breast cancer
    Karin B Michels
    Department of Obstetrics, Gynecology and Reproductive Biology, Obstetrics and Gynecology Epidemiology Center, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    Int J Cancer 130:902-9. 2012
    ....
  38. ncbi request reprint Plasma adiponectin concentrations and risk of incident breast cancer
    Shelley S Tworoger
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, 181 Longwood Avenue, Third Floor, Boston, Massachusetts 02115, USA
    J Clin Endocrinol Metab 92:1510-6. 2007
    ..Therefore, we conducted a prospective case-control study nested within the Nurses' Health Study (NHS) and NHSII cohorts examining the association between plasma adiponectin concentrations and breast cancer risk...
  39. doi request reprint A prospective study of leisure-time physical activity and risk of incident epithelial ovarian cancer: Impact by menopausal status
    Tianyi Huang
    Channing Division of Network Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA
    Int J Cancer 138:843-52. 2016
    ..Our data do not support a protective role of physical activity for ovarian cancer. The increased risk associated with physical activity during premenopausal years and the underlying etiology require further investigation. ..
  40. doi request reprint Dietary Fat and Fiber Intakes Are Not Associated with Patterns of Urinary Estrogen Metabolites in Premenopausal Women
    Hannah Oh
    Department of Epidemiology, Department of Nutrition, and Channing Division of Network Medicine, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA
    J Nutr 145:2109-16. 2015
    ..Interindividual differences in the bioavailability of potentially carcinogenic estrogen and estrogen metabolites (EMs) may play a role in the risk of breast cancer...
  41. doi request reprint Alcohol consumption and risk of breast cancer by molecular subtype: Prospective analysis of the nurses' health study after 26 years of follow-up
    Kelly A Hirko
    Channing Division of Network Medicine, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA, 02115
    Int J Cancer 138:1094-101. 2016
    ..Given that ERs are expressed in luminal A but not in HER2-type tumors, our findings suggest that other mechanisms may play a role in the association between alcohol and breast cancer. ..
  42. pmc Plasma C-peptide, mammographic breast density, and risk of invasive breast cancer
    Thomas P Ahern
    Authors Affiliations Channing Division of Network Medicine, Brigham and Women s Hospital and Harvard Medical School Department of Epidemiology Department of Nutrition, Harvard School of Public Health, Boston Division of Biostatistics and Epidemiology, University of Massachusetts School of Public Health and Health Sciences, Amherst, Massachusetts and Department of Medicine, McGill University, Montreal, Quebec, Canada
    Cancer Epidemiol Biomarkers Prev 22:1786-96. 2013
    ..We measured associations between c-peptide (a molar marker of insulin secretion), breast cancer risk, and breast density measurements in case-control studies nested within the Nurses' Health Study and Nurses' Health Study II cohorts...
  43. pmc Teenage acne and cancer risk in US women: A prospective cohort study
    Mingfeng Zhang
    Department of Dermatology, Brigham and Women s Hospital, and Harvard Medical School, Boston, Massachusetts
    Cancer 121:1681-7. 2015
    ..Acne reflects hormone imbalance and is a key component of several systemic diseases. We hypothesized that diagnosis of acne as a teenager might predict subsequent risk of hormone-related cancers...
  44. pmc Dietary fat intake in relation to lethal breast cancer in two large prospective cohort studies
    Caroline E Boeke
    Department of Epidemiology, Harvard School of Public Health, 677 Huntington Avenue, Boston, MA, 02115, USA
    Breast Cancer Res Treat 146:383-92. 2014
    ....
  45. pmc Physical activity and risk of endometrial adenocarcinoma in the Nurses' Health Study
    Mengmeng Du
    Department of Epidemiology, University of Washington School of Public Health, Seattle, WA Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA
    Int J Cancer 134:2707-16. 2014
    ..Greater recent physical activity, including activity of moderate duration and intensity such as walking, may reduce endometrial adenocarcinoma risk. This relation is largely mediated or confounded by body mass index...
  46. pmc Association between reproductive factors and urinary estrogens and estrogen metabolites in premenopausal women
    Renée T Fortner
    Brigham and Women s Hospital, Boston, MA, USA
    Cancer Epidemiol Biomarkers Prev 21:959-68. 2012
    ..Little is known about relationships among reproductive factors, estrogens and estrogen metabolites (jointly referred to as EM), and estrogen metabolism patterns...
  47. pmc Energy balance, early life body size, and plasma prolactin levels in postmenopausal women
    Xuefen Su
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, 181 Longwood Ave, 3rd Floor, Boston, MA 02115, USA
    Cancer Causes Control 20:253-62. 2009
    ....
  48. doi request reprint Premenopausal plasma carotenoids, fluorescent oxidation products, and subsequent breast cancer risk in the nurses' health studies
    Julia S Sisti
    Departments of Epidemiology, Harvard T H Chan School of Public Health, 677 Huntington Avenue, Boston, MA, 02115, USA
    Breast Cancer Res Treat 151:415-25. 2015
    ..We observed evidence of interactions between some SNPs and carotenoid levels on risk. We did not observe consistent associations between circulating levels of premenopausal carotenoids or FlOP levels and breast cancer risk...
  49. pmc Plasma florescent oxidation products and breast cancer risk: repeated measures in the Nurses' Health Study
    Renée T Fortner
    Channing Division of Network Medicine, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, 181 Longwood Ave, Boston, MA, 02115, USA
    Breast Cancer Res Treat 141:307-16. 2013
    ..6, 95 % CI 1.0-2.4, p trend = 0.02). We did not observe important associations between FlOP and breast cancer risk in this large prospective study, though our data suggest women with consistently high FlOP_320 may be at increased risk...
  50. pmc A 20-year prospective study of plasma prolactin as a risk marker of breast cancer development
    Shelley S Tworoger
    Channing Division of Network Medicine, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
    Cancer Res 73:4810-9. 2013
    ..This corresponds with biologic data that prolactin is etiologically important in tumor promotion...
  51. pmc Postmenopausal plasma sex hormone levels and breast cancer risk over 20 years of follow-up
    Xuehong Zhang
    Channing Division of Network Medicine, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA, USA
    Breast Cancer Res Treat 137:883-92. 2013
    ..001) versus 0.6 (0.3-1.2; p (trend) = 0.35) for testosterone. One measure of circulating sex hormones in postmenopausal women can predict risk of hormone receptor positive breast cancer for up to 16-20 years...
  52. ncbi request reprint Plasma prolactin concentrations and risk of postmenopausal breast cancer
    Shelley S Tworoger
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
    Cancer Res 64:6814-9. 2004
    ..Our prospective data suggest that plasma prolactin concentrations are associated with an increased risk of postmenopausal breast cancer, particularly for estrogen receptor+/progesterone receptor+ cancers, and independently of estradiol...
  53. doi request reprint Reproductive risk factors in relation to molecular subtypes of breast cancer: Results from the nurses' health studies
    Julia S Sisti
    Department of Epidemiology, Harvard T H Chan School of Public Health, Boston, MA
    Int J Cancer 138:2346-56. 2016
    ..Our results support previous reports that lactation is protective against basal-like tumors, representing a potential modifiable risk factor for this aggressive subtype. ..
  54. doi request reprint Adult body size and physical activity in relation to risk of breast cancer according to tumor androgen receptor status
    Xuehong Zhang
    Channing Division of Network Medicine, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts
    Cancer Epidemiol Biomarkers Prev 24:962-8. 2015
    ..Obesity and physical activity have been hypothesized to affect breast cancer risk partly via the androgen signaling pathway. We conducted the first study to evaluate these associations by tumor androgen receptor (AR) status...
  55. doi request reprint Caffeine, coffee, and tea intake and urinary estrogens and estrogen metabolites in premenopausal women
    Julia S Sisti
    Department of Epidemiology, Harvard T H Chan School of Public Health, Boston, Massachusetts
    Cancer Epidemiol Biomarkers Prev 24:1174-83. 2015
    ..Prior studies have found weak inverse associations between breast cancer and caffeine and coffee intake, possibly mediated through their effects on sex hormones...
  56. pmc Adolescent carotenoid intake and benign breast disease
    Caroline E Boeke
    Departments of Epidemiology and Channing Division of Network Medicine, Department of Medicine, Brigham and Women s Hospital, Boston, Massachusetts
    Pediatrics 133:e1292-8. 2014
    ..Exposure to carotenoids may be most important during adolescence when breast tissue is still developing. We examined adolescent carotenoid intake in relation to BBD in young women...
  57. pmc Determinants of plasma 25-hydroxyvitamin D and development of prediction models in three US cohorts
    Kimberly A Bertrand
    Department of Epidemiology, Harvard School of Public Health, 677 Huntington Avenue, Boston, MA 02115, USA
    Br J Nutr 108:1889-96. 2012
    ....
  58. pmc Endogenous estrogen, testosterone and progesterone levels in relation to breast cancer risk
    Susan E Hankinson
    Channing Laboratory, Department of Medicine, 181 Longwood Avenue, Harvard Medical School, Brigham and Women s Hospital, MA 02115, USA
    J Steroid Biochem Mol Biol 106:24-30. 2007
    ..However, both positive and null associations have been observed with estrogens and progesterone and clearly more evaluation is needed...
  59. doi request reprint Alcohol Consumption and Urinary Estrogens and Estrogen Metabolites in Premenopausal Women
    Terryl J Hartman
    Department of Epidemiology, Rollins School of Public Health and Winship Cancer Institute, Emory University, 1518 Clifton Road NE, CNR 3035, Atlanta, GA, 30322, USA
    Horm Cancer 7:65-74. 2016
    ..Additional studies of premenopausal women are needed to further explore the association of alcohol, particularly the specific types of alcohol, on patterns of estrogen metabolism in blood, urine, and tissue. ..
  60. doi request reprint Adolescent and Early Adulthood Dietary Carbohydrate Quantity and Quality in Relation to Breast Cancer Risk
    Maryam S Farvid
    Department of Nutrition, Harvard T H Chan School of Public Health, Boston, Massachusetts Department of Community Nutrition, Faculty of Nutrition Sciences and Food Technology, Shahid Beheshti University of Medical Sciences, Tehran, Iran
    Cancer Epidemiol Biomarkers Prev 24:1111-20. 2015
    ..We investigated quantity and quality of dietary carbohydrate as well as insulin load and insulin index during adolescence and also early adulthood in relation to risk of breast cancer in the Nurses' Health Study II...
  61. pmc The interaction between early-life body size and physical activity on risk of breast cancer
    Hannah Oh
    Department of Epidemiology, Harvard School of Public Health, Boston, MA
    Int J Cancer 137:571-81. 2015
    ..Being lean during early life is a risk factor for breast cancer among both inactive and active girls. Adolescent physical activity did not significantly modify the association, although some interaction cannot be excluded...
  62. pmc Premenopausal plasma 25-hydroxyvitamin D, mammographic density, and risk of breast cancer
    Kimberly A Bertrand
    Department of Epidemiology, Harvard School of Public Health, 677 Huntington Avenue, Boston, MA, 02115, USA
    Breast Cancer Res Treat 149:479-87. 2015
    ..There was evidence that the association between premenopausal 25(OH)D and breast cancer risk varies by mammographic density, with an inverse association apparent only among women with high mammographic density...
  63. pmc Adolescent meat intake and breast cancer risk
    Maryam S Farvid
    Department of Nutrition, Harvard School of Public Health, Boston, MA Department of Community Nutrition, Faculty of Nutrition Sciences and Food Technology, Shahid Beheshti University of Medical Sciences, Tehran, Iran
    Int J Cancer 136:1909-20. 2015
    ..In conclusion, higher consumption of red meat during adolescence was associated with premenopausal breast cancer. Substituting other dietary protein sources for red meat in adolescent diet may decrease premenopausal breast cancer risk...
  64. pmc Short-term weight gain and breast cancer risk by hormone receptor classification among pre- and postmenopausal women
    Bernard Rosner
    Channing Division of Network Medicine, Brigham and Women s Hospital and Harvard Medical School, 181 Longwood Avenue, Boston, MA, 02115, USA
    Breast Cancer Res Treat 150:643-53. 2015
    ..The association was stronger for ER+/PR- and ER-/PR- than for ER+/PR+ breast cancer...
  65. pmc Adolescent physical activity in relation to breast cancer risk
    Caroline E Boeke
    Department of Epidemiology, Harvard School of Public Health, 677 Huntington Avenue, Boston, MA, 02115, USA
    Breast Cancer Res Treat 145:715-24. 2014
    ..Overall, adolescent physical activity was not associated with breast cancer risk. However, we observed a suggestive inverse association of physical activity at ages 14-22 years with premenopausal breast cancer...
  66. pmc Within-person reproducibility of urinary bisphenol A and phthalate metabolites over a 1 to 3 year period among women in the Nurses' Health Studies: a prospective cohort study
    Mary K Townsend
    Channing Division of Network Medicine, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, 181 Longwood Ave, Boston, MA 02115, USA
    Environ Health 12:80. 2013
    ..Therefore, we assessed within-person reproducibility of bisphenol A, eight phthalate metabolites, and phthalic acid in spot urine samples over 1 to 3 years among women enrolled in two large cohort studies...
  67. pmc Association of urinary concentrations of bisphenol A and phthalate metabolites with risk of type 2 diabetes: a prospective investigation in the Nurses' Health Study (NHS) and NHSII cohorts
    Qi Sun
    Channing Division of Network Medicine, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts, USA
    Environ Health Perspect 122:616-23. 2014
    ..Prospective evidence regarding associations for exposures to bisphenol A (BPA) and phthalates with type 2 diabetes (T2D) is lacking...
  68. pmc Analgesic use and patterns of estrogen metabolism in premenopausal women
    Renée T Fortner
    Channing Division of Network Medicine, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, 181 Longwood Ave, Boston, MA, 02115, USA
    Horm Cancer 5:104-12. 2014
    ..01, p trend = 0.05). This study provides the first assessment of analgesic use and patterns of estrogen metabolism in women. While we observed some associations between analgesics and individual EM, no clear patterns emerged. ..
  69. pmc High anthocyanin intake is associated with a reduced risk of myocardial infarction in young and middle-aged women
    Aedin Cassidy
    Department of Nutrition, Norwich Medical School, University of East Anglia, Norwich, UK
    Circulation 127:188-96. 2013
    ..Dietary flavonoids exert potential beneficial effects on endothelial function in short-term trials; however, the relationship between habitual intake and risk of MI in women is unknown...
  70. pmc Circulating sex steroids and breast cancer risk in premenopausal women
    Susan E Hankinson
    Channing Laboratory, Department of Medicine, Harvard Medical School and Brigham and Women s Hospital, Boston, MA 02115, USA
    Horm Cancer 1:2-10. 2010
    ..In this review, we summarize current evidence and identify gaps and inconsistencies that need to be addressed in future studies of sex steroids and premenopausal breast cancer risk...
  71. pmc Plasma free 25-hydroxyvitamin D, vitamin D binding protein, and risk of breast cancer in the Nurses' Health Study II
    Jun Wang
    Division of Biostatistics and Epidemiology, School of Public Health and Health Sciences, University of Massachusetts Amherst, 715 N Pleasant Street, Amherst, MA, 01003, USA
    Cancer Causes Control 25:819-27. 2014
    ..Vitamin D binding protein (DBP) influences the free 25(OH)D levels and thus possibly the biological activities of vitamin D...
  72. pmc Migraine and breast cancer risk: a prospective cohort study and meta-analysis
    Anke C Winter
    Division of Public Health Sciences, Department of Surgery, Washington University School of Medicine, St Louis, MO ACW Channing Division of Network Medicine, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA MSR, RTF, AHE, RMT Department of Epidemiology, Harvard School of Public Health, Boston, MA MSR, RTF, AHE, RMT Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA TK Team Neuroepidemiology, INSERM Research Center for Epidemiology and Biostatistics U897, Bordeaux, France TK University of Bordeaux, Bordeaux, France TK
    J Natl Cancer Inst 107:381. 2015
    ..The evidence for an association between migraine and breast cancer risk is inconclusive. While female sex hormones have been proposed as one underlying mechanism, data on sex hormone levels in migraineurs are sparse...
  73. pmc Alcohol consumption in relation to plasma sex hormones, prolactin, and sex hormone-binding globulin in premenopausal women
    Kelly A Hirko
    Channing Division of Network Medicine, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts
    Cancer Epidemiol Biomarkers Prev 23:2943-53. 2014
    ..Alcohol consumption is a consistent risk factor for breast cancer, and evidence suggests premenopausal plasma hormones are associated with breast cancer...
  74. pmc Premenopausal plasma ferritin levels, HFE polymorphisms, and risk of breast cancer in the nurses' health study II
    Rebecca E Graff
    Authors Affiliations Departments of Epidemiology, Biostatistics, and Nutrition Program in Molecular and Genetic Epidemiology, Harvard School of Public Health and Department of Medicine, Channing Division of Network Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts
    Cancer Epidemiol Biomarkers Prev 23:516-24. 2014
    ..Iron may be responsible by contributing to oxidative stress or effects on immune function...
  75. pmc Premenopausal dietary fat in relation to pre- and post-menopausal breast cancer
    Maryam S Farvid
    Department of Nutrition, Harvard School of Public Health, Boston, 02115, MA, USA
    Breast Cancer Res Treat 145:255-65. 2014
    ..Our finding suggests a positive association between early adult intake of animal fat and breast cancer risk...
  76. pmc Associations between dietary acrylamide intake and plasma sex hormone levels
    Janneke G Hogervorst
    Authors Affiliations Department of Epidemiology, GROW School for Oncology and Developmental Biology, Maastricht University, Maastricht, The Netherlands Department of Epidemiology, Harvard School of Public Health Channing Division of Network Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston and Division of Biostatistics and Epidemiology, School of Public Health and Health Sciences, University of Massachusetts, Amherst, Massachusetts
    Cancer Epidemiol Biomarkers Prev 22:2024-36. 2013
    ..Epidemiologic studies have observed positive associations between acrylamide intake and endometrial, ovarian, and breast cancer risks, which suggest that acrylamide may have sex-hormonal effects...
  77. pmc Association between cutaneous nevi and breast cancer in the Nurses' Health Study: a prospective cohort study
    Mingfeng Zhang
    Department of Dermatology, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts, United States of America
    PLoS Med 11:e1001659. 2014
    ..Cutaneous nevi are suggested to be hormone-related. We hypothesized that the number of cutaneous nevi might be a phenotypic marker of plasma hormone levels and predict subsequent breast cancer risk...