A Heather Eliassen

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. pmc Circulating carotenoids and risk of breast cancer: pooled analysis of eight prospective studies
    A Heather Eliassen
    Channing Division of Network Medicine, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, 181 Longwood Ave, Boston, MA 02115, USA
    J Natl Cancer Inst 104:1905-16. 2012
  2. pmc Urinary estrogens and estrogen metabolites and subsequent risk of breast cancer among premenopausal women
    A Heather Eliassen
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA
    Cancer Res 72:696-706. 2012
  3. pmc Plasma 25-hydroxyvitamin D and risk of breast cancer in the Nurses' Health Study II
    A Heather Eliassen
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, Boston, MA 02115, USA
    Breast Cancer Res 13:R50. 2011
  4. ncbi request reprint Circulating insulin and c-peptide levels and risk of breast cancer among predominately premenopausal women
    A Heather Eliassen
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, 181 Longwood Avenue, Boston, MA 02115, USA
    Cancer Epidemiol Biomarkers Prev 16:161-4. 2007
  5. pmc Physical activity and risk of breast cancer among postmenopausal women
    A Heather Eliassen
    Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    Arch Intern Med 170:1758-64. 2010
  6. ncbi request reprint Endogenous hormone levels and risk of breast, endometrial and ovarian cancers: prospective studies
    A Heather Eliassen
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, Boston, MA 02115, USA
    Adv Exp Med Biol 630:148-65. 2008
  7. pmc Circulating 2-hydroxy- and 16alpha-hydroxy estrone levels and risk of breast cancer among postmenopausal women
    A Heather Eliassen
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, 181 Longwood Avenue, Boston, MA 02115, USA
    Cancer Epidemiol Biomarkers Prev 17:2029-35. 2008
  8. pmc Use of aspirin, other nonsteroidal anti-inflammatory drugs, and acetaminophen and risk of breast cancer among premenopausal women in the Nurses' Health Study II
    A Heather Eliassen
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, 181 Longwood Ave, Boston, MA 02115, USA
    Arch Intern Med 169:115-21; discussion 121. 2009
  9. pmc Reproducibility of fifteen urinary estrogens and estrogen metabolites over a 2- to 3-year period in premenopausal women
    A Heather Eliassen
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
    Cancer Epidemiol Biomarkers Prev 18:2860-8. 2009
  10. ncbi request reprint Reproductive factors and family history of breast cancer in relation to plasma prolactin levels in premenopausal and postmenopausal women
    A Heather Eliassen
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
    Int J Cancer 120:1536-41. 2007

Detail Information

Publications43

  1. pmc Circulating carotenoids and risk of breast cancer: pooled analysis of eight prospective studies
    A Heather Eliassen
    Channing Division of Network Medicine, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, 181 Longwood Ave, Boston, MA 02115, USA
    J Natl Cancer Inst 104:1905-16. 2012
    ..Most, but not all, past studies of circulating carotenoids and breast cancer have found an inverse association with at least one carotenoid, although the specific carotenoid has varied across studies...
  2. pmc Urinary estrogens and estrogen metabolites and subsequent risk of breast cancer among premenopausal women
    A Heather Eliassen
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA
    Cancer Res 72:696-706. 2012
    ..The inverse associations with parent estrogen metabolites and the parent estrogen metabolite/non-parent estrogen metabolite ratio suggest that women with higher urinary excretion of parent estrogens are at lower risk...
  3. pmc Plasma 25-hydroxyvitamin D and risk of breast cancer in the Nurses' Health Study II
    A Heather Eliassen
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, Boston, MA 02115, USA
    Breast Cancer Res 13:R50. 2011
    ..Vitamin D comes from dietary intake and sun exposure and plasma levels of 25-hydroxyvitamin D (25(OH)D) are considered the best measure of vitamin D status...
  4. ncbi request reprint Circulating insulin and c-peptide levels and risk of breast cancer among predominately premenopausal women
    A Heather Eliassen
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, 181 Longwood Avenue, Boston, MA 02115, USA
    Cancer Epidemiol Biomarkers Prev 16:161-4. 2007
    ..These associations did not differ by age, body mass index, or waist-to-hip ratio. Overall, higher levels of insulin and c-peptide were not associated with a higher risk of breast cancer among predominantly premenopausal women...
  5. pmc Physical activity and risk of breast cancer among postmenopausal women
    A Heather Eliassen
    Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    Arch Intern Med 170:1758-64. 2010
    ..Although greater activity has been related to lower postmenopausal breast cancer risk, important details remain unclear, including type, intensity, and timing of activity and whether the association varies by subgroups...
  6. ncbi request reprint Endogenous hormone levels and risk of breast, endometrial and ovarian cancers: prospective studies
    A Heather Eliassen
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, Boston, MA 02115, USA
    Adv Exp Med Biol 630:148-65. 2008
    ..Clearly more evaluation is needed to confirm the role of endogenous hormones in premenopausal breast cancer, endometrial cancer and ovarian cancer...
  7. pmc Circulating 2-hydroxy- and 16alpha-hydroxy estrone levels and risk of breast cancer among postmenopausal women
    A Heather Eliassen
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, 181 Longwood Avenue, Boston, MA 02115, USA
    Cancer Epidemiol Biomarkers Prev 17:2029-35. 2008
    ..The significant positive associations with 2-OH estrone and the 2-OH:16-OH estrone ratio among women with ER-negative/PR-negative tumors needs to be replicated in future studies...
  8. pmc Use of aspirin, other nonsteroidal anti-inflammatory drugs, and acetaminophen and risk of breast cancer among premenopausal women in the Nurses' Health Study II
    A Heather Eliassen
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, 181 Longwood Ave, Boston, MA 02115, USA
    Arch Intern Med 169:115-21; discussion 121. 2009
    ..In addition, the chemopreventive use of NSAIDs is increasingly common for heart disease and colon cancer. Evidence of a protective association with breast cancer risk has been inconsistent, and few data exist for premenopausal women...
  9. pmc Reproducibility of fifteen urinary estrogens and estrogen metabolites over a 2- to 3-year period in premenopausal women
    A Heather Eliassen
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
    Cancer Epidemiol Biomarkers Prev 18:2860-8. 2009
    ..Within-person reproducibility over time for most EM measures is comparable to or better than that for well-vetted biomarkers such as plasma cholesterol and, in postmenopausal women, estradiol...
  10. ncbi request reprint Reproductive factors and family history of breast cancer in relation to plasma prolactin levels in premenopausal and postmenopausal women
    A Heather Eliassen
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
    Int J Cancer 120:1536-41. 2007
    ..9 ng/mL vs. 14.3 ng/mL, p=0.04) but not postmenopausal (p=0.73) women. In conclusion, the associations of parity and family history with breast cancer risk may be mediated, at least in part, by prolactin levels...
  11. ncbi request reprint Endogenous steroid hormone concentrations and risk of breast cancer among premenopausal women
    A Heather Eliassen
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, 181 Longwood Ave, Boston, MA 02115, USA
    J Natl Cancer Inst 98:1406-15. 2006
    ..We prospectively evaluated associations between plasma sex hormone levels and breast cancer risk among premenopausal women in a case-control study nested within the Nurses' Health Study II...
  12. ncbi request reprint Serum lipids, lipid-lowering drugs, and the risk of breast cancer
    A Heather Eliassen
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, Mass 02115, USA
    Arch Intern Med 165:2264-71. 2005
    ..The relation between serum cholesterol levels and breast cancer risk is itself unclear; because cholesterol is the precursor to sex steroid hormones, higher levels could plausibly increase risk...
  13. ncbi request reprint Tubal sterilization in relation to breast cancer risk
    A Heather Eliassen
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
    Int J Cancer 118:2026-30. 2006
    ....
  14. pmc Biomarker validation of dietary intervention in two multiethnic populations
    A Heather Eliassen
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, 181 Longwood Ave, Boston, MA 02115, USA
    Prev Chronic Dis 3:A44. 2006
    ..The Healthy Directions intervention studies were designed to increase multivitamin use, fruit and vegetable consumption, and physical activity in working-class, multiethnic populations...
  15. ncbi request reprint Endogenous steroid hormone concentrations and risk of breast cancer: does the association vary by a woman's predicted breast cancer risk?
    A Heather Eliassen
    Channing Laboratory, Brigham and Women s Hospital, Boston, MA 02115, USA
    J Clin Oncol 24:1823-30. 2006
    ....
  16. ncbi request reprint Adult weight change and risk of postmenopausal breast cancer
    A Heather Eliassen
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, Mass 02115, USA
    JAMA 296:193-201. 2006
    ..Endogenous hormones are a primary cause of breast cancer. Adiposity affects circulating hormones, particularly in postmenopausal women, and may be a modifiable risk factor for breast cancer...
  17. ncbi request reprint Endogenous estrogen, androgen, and progesterone concentrations and breast cancer risk among postmenopausal women
    Stacey A Missmer
    Channing Laboratory, Brigham and Women s Hospital and Harvard Medical School, 181 Longwood Avenue, Boston, MA 02115, USA
    J Natl Cancer Inst 96:1856-65. 2004
    ..Nor has the relation between breast cancer risk and postmenopausal progesterone levels been investigated. We prospectively investigated these relations in a case-control study nested within the Nurses' Health Study...
  18. ncbi request reprint Physical activity and inactivity in relation to sex hormone, prolactin, and insulin-like growth factor concentrations in premenopausal women - exercise and premenopausal hormones
    Shelley S Tworoger
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, 181 Longwood Ave, 3rd Floor, Boston, MA 02115, USA
    Cancer Causes Control 18:743-52. 2007
    ..These cross-sectional results suggest that physical activity and inactivity have limited associations with premenopausal sex hormone and growth factor levels, except possibly luteal estrogens...
  19. pmc Reproducibility of plasma and urine biomarkers among premenopausal and postmenopausal women from the Nurses' Health Studies
    Joanne Kotsopoulos
    Channing Laboratory, 181 Longwood Avenue, Boston, MA 02115, USA
    Cancer Epidemiol Biomarkers Prev 19:938-46. 2010
    ..Temporal variability of biomarkers should be evaluated before their use in epidemiologic studies...
  20. ncbi request reprint A prospective study of plasma prolactin concentrations and risk of premenopausal and postmenopausal breast cancer
    Shelley S Tworoger
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
    J Clin Oncol 25:1482-8. 2007
    ....
  21. pmc The association of plasma androgen levels with breast, ovarian and endometrial cancer risk factors among postmenopausal women
    Kim N Danforth
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
    Int J Cancer 126:199-207. 2010
    ..Future studies are needed to clarify further which lifestyle factors modulate androgen levels...
  22. ncbi request reprint The association of plasma DHEA and DHEA sulfate with breast cancer risk in predominantly premenopausal women
    Shelley S Tworoger
    Channing Laboratory, 181 Longwood Avenue, 3rd Floor, Boston, MA 02115, USA
    Cancer Epidemiol Biomarkers Prev 15:967-71. 2006
    ....
  23. pmc Analgesic use and sex steroid hormone concentrations in postmenopausal women
    Margaret A Gates
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
    Cancer Epidemiol Biomarkers Prev 19:1033-41. 2010
    ..04). Among postmenopausal women, regular users of aspirin and other analgesics may have lower estrogen levels than nonusers, which could contribute to a decreased risk of breast or ovarian cancer among analgesic users...
  24. ncbi request reprint Body shape throughout life and correlations with IGFs and GH
    Eva S Schernhammer
    Channing Laboratory, Department of Medicine, Harvard Medical School, Brigham and Women s Hospital, 181 Longwood Avenue, Boston 02115, Massachusetts, USA
    Endocr Relat Cancer 14:721-32. 2007
    ..Our results suggest that childhood and adult body size may affect premenopausal breast cancer risk differently than birth weight, through associations with IGF and GH levels...
  25. pmc Body size in relation to urinary estrogens and estrogen metabolites (EM) among premenopausal women during the luteal phase
    Jing Xie
    Channing Division of Network Medicine, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, 181 Longwood Avenue, Boston, MA 02115, USA
    Horm Cancer 3:249-60. 2012
    ..Our results suggest that height and current BMI are associated with estrogen metabolism profiles in premenopausal women. Further studies with timed urine and blood collections are required to confirm and extend our findings...
  26. pmc β-Carotene 15,15'-monooxygenase 1 single nucleotide polymorphisms in relation to plasma carotenoid and retinol concentrations in women of European descent
    Sara J Hendrickson
    Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA
    Am J Clin Nutr 96:1379-89. 2012
    ....
  27. ncbi request reprint Birthweight and body size throughout life in relation to sex hormones and prolactin concentrations in premenopausal women
    Shelley S Tworoger
    Channing Laboratory, 181 Longwood Avenue, 3rd Floor, Boston, MA 02115, USA
    Cancer Epidemiol Biomarkers Prev 15:2494-501. 2006
    ..Our results suggest that effects on premenopausal sex hormone levels may be one mechanism through which adult adiposity, but not birthweight or childhood body size, affects premenopausal breast cancer risk...
  28. pmc Relationship between caffeine intake and plasma sex hormone concentrations in premenopausal and postmenopausal women
    Joanne Kotsopoulos
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA
    Cancer 115:2765-74. 2009
    ..Caffeine intake may decrease risk of breast and ovarian cancer, although the data are not entirely consistent. Whether or not caffeine affects cancer risk by altering sex hormone levels is currently unknown...
  29. pmc Adult weight change and incidence of premenopausal breast cancer
    Karin B Michels
    Department of Obstetrics, Gynecology and Reproductive Biology, Obstetrics and Gynecology Epidemiology Center, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    Int J Cancer 130:902-9. 2012
    ....
  30. ncbi request reprint Plasma adiponectin concentrations and risk of incident breast cancer
    Shelley S Tworoger
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, 181 Longwood Avenue, Third Floor, Boston, Massachusetts 02115, USA
    J Clin Endocrinol Metab 92:1510-6. 2007
    ..Therefore, we conducted a prospective case-control study nested within the Nurses' Health Study (NHS) and NHSII cohorts examining the association between plasma adiponectin concentrations and breast cancer risk...
  31. pmc Plasma enterolactone and breast cancer risk in the Nurses' Health Study II
    Jing Xie
    Channing Division of Network Medicine, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, 181 Longwood Avenue, Boston, MA, 02115, USA
    Breast Cancer Res Treat 139:801-9. 2013
    ..This should be confirmed in future studies. ..
  32. pmc Urinary estrogens and estrogen metabolites and mammographic density in premenopausal women
    Kimberly A Bertrand
    Department of Epidemiology, Harvard School of Public Health, 677 Huntington Avenue, Boston, MA 02115, USA
    Breast Cancer Res Treat 136:277-87. 2012
    ..If these profiles are associated with breast cancer risk, they may not act through influences on breast density...
  33. pmc Association between reproductive factors and urinary estrogens and estrogen metabolites in premenopausal women
    Renée T Fortner
    Brigham and Women s Hospital, Boston, MA, USA
    Cancer Epidemiol Biomarkers Prev 21:959-68. 2012
    ..Little is known about relationships among reproductive factors, estrogens and estrogen metabolites (jointly referred to as EM), and estrogen metabolism patterns...
  34. pmc Energy balance, early life body size, and plasma prolactin levels in postmenopausal women
    Xuefen Su
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, 181 Longwood Ave, 3rd Floor, Boston, MA 02115, USA
    Cancer Causes Control 20:253-62. 2009
    ....
  35. pmc Postmenopausal plasma sex hormone levels and breast cancer risk over 20 years of follow-up
    Xuehong Zhang
    Channing Division of Network Medicine, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA, USA
    Breast Cancer Res Treat 137:883-92. 2013
    ..001) versus 0.6 (0.3-1.2; p (trend) = 0.35) for testosterone. One measure of circulating sex hormones in postmenopausal women can predict risk of hormone receptor positive breast cancer for up to 16-20 years...
  36. ncbi request reprint Plasma prolactin concentrations and risk of postmenopausal breast cancer
    Shelley S Tworoger
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
    Cancer Res 64:6814-9. 2004
    ..Our prospective data suggest that plasma prolactin concentrations are associated with an increased risk of postmenopausal breast cancer, particularly for estrogen receptor+/progesterone receptor+ cancers, and independently of estradiol...
  37. pmc Determinants of plasma 25-hydroxyvitamin D and development of prediction models in three US cohorts
    Kimberly A Bertrand
    Department of Epidemiology, Harvard School of Public Health, 677 Huntington Avenue, Boston, MA 02115, USA
    Br J Nutr 108:1889-96. 2012
    ....
  38. pmc Endogenous estrogen, testosterone and progesterone levels in relation to breast cancer risk
    Susan E Hankinson
    Channing Laboratory, Department of Medicine, 181 Longwood Avenue, Harvard Medical School, Brigham and Women s Hospital, MA 02115, USA
    J Steroid Biochem Mol Biol 106:24-30. 2007
    ..However, both positive and null associations have been observed with estrogens and progesterone and clearly more evaluation is needed...
  39. pmc A 20-year prospective study of plasma prolactin as a risk marker of breast cancer development
    Shelley S Tworoger
    Authors Affiliations Channing Division of Network Medicine, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School Department of Epidemiology, Harvard School of Public Health Department of Pathology, Massachusetts General Hospital Division of Biostatistics and Epidemiology, School of Public Health and Health Sciences, University of Massachusetts Department of Biostatistics, Harvard School of Public Health, Boston, Massachusetts
    Cancer Res 73:4810-9. 2013
    ..This corresponds with biologic data that prolactin is etiologically important in tumor promotion. Cancer Res; 73(15); 4810-9. ©2013 AACR. ..
  40. pmc Analgesic use in relation to sex hormone and prolactin concentrations in premenopausal women
    Scott R Bauer
    Channing Division of Network Medicine, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, 181 Longwood Ave, 3rd Floor, Boston, MA, 02115, USA
    Cancer Causes Control 24:1087-97. 2013
    ..Common analgesics (aspirin, non-aspirin NSAIDs, and acetaminophen) may be associated with hormone-related cancers, possibly via effects on sex hormone and prolactin concentrations...
  41. pmc High anthocyanin intake is associated with a reduced risk of myocardial infarction in young and middle-aged women
    Aedin Cassidy
    Department of Nutrition, Norwich Medical School, University of East Anglia, Norwich, UK
    Circulation 127:188-96. 2013
    ..Dietary flavonoids exert potential beneficial effects on endothelial function in short-term trials; however, the relationship between habitual intake and risk of MI in women is unknown...
  42. pmc Circulating sex steroids and breast cancer risk in premenopausal women
    Susan E Hankinson
    Channing Laboratory, Department of Medicine, Harvard Medical School and Brigham and Women s Hospital, Boston, MA 02115, USA
    Horm Cancer 1:2-10. 2010
    ..In this review, we summarize current evidence and identify gaps and inconsistencies that need to be addressed in future studies of sex steroids and premenopausal breast cancer risk...
  43. pmc Plasma carotenoid- and retinol-weighted multi-SNP scores and risk of breast cancer in the National Cancer Institute Breast and Prostate Cancer Cohort Consortium
    Sara J Hendrickson
    Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
    Cancer Epidemiol Biomarkers Prev 22:927-36. 2013
    ..We determined associations between variants in BCMO1 and breast cancer risk in a large cohort consortium...