M Eikermann

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. pmc The influence of aging on pharyngeal collapsibility during sleep
    Matthias Eikermann
    Department of Sleep Medicine, Brigham and Women s Hospital, Harvard Medical School, 75 Francis St, Boston, MA 02115, USA
    Chest 131:1702-9. 2007
  2. ncbi request reprint Muscle force and fatigue in patients with sepsis and multiorgan failure
    M Eikermann
    Sleep Disorders Research Program, Brigham and Women s Hospital and Harvard Medical School, MA 02115, 75 Francis Street, Boston, MA 02115, USA
    Intensive Care Med 32:251-9. 2006
  3. ncbi request reprint Postoperative upper airway obstruction after recovery of the train of four ratio of the adductor pollicis muscle from neuromuscular blockade
    Matthias Eikermann
    Klinik für Anästhesiologie und Intensivmedizin, Universitatsklinikum Essen, Germany
    Anesth Analg 102:937-42. 2006
  4. ncbi request reprint The predisposition to inspiratory upper airway collapse during partial neuromuscular blockade
    Matthias Eikermann
    Oberarzt der Klinik für Anästhesiologie und Intensivmedizin, Universitatsklinikum Essen, Hufelandstrasse 55, D 45122 Essen, Germany
    Am J Respir Crit Care Med 175:9-15. 2007
  5. ncbi request reprint Preventive effects of perioperative parecoxib on post-discectomy pain
    G Riest
    Klinik für Anästhesiologie und Intensivmedizin, Universitaetsklinikum Essen, Germany
    Br J Anaesth 100:256-62. 2008
  6. doi request reprint Development and longitudinal validation of the overall benefit of analgesia score: a simple multi-dimensional quality assessment instrument
    N Lehmann
    Institut für Medizinische Informatik, Biometrie und Epidemiologie, Universitat Duisburg Essen, Universitatsklinikum Essen, Essen, Germany
    Br J Anaesth 105:511-8. 2010
  7. ncbi request reprint Incidence and duration of residual paralysis at the end of surgery after multiple administrations of cisatracurium and rocuronium
    D M Maybauer
    Klinik für Anästhesiologie und Intensivmedizin, Philipps Universitat Marburg, Germany
    Anaesthesia 62:12-7. 2007
  8. pmc Effects of pentobarbital on upper airway patency during sleep
    M Eikermann
    Dept of Anesthesia and Critical Care, Massachusetts General Hospital, 55 Fruit St, Boston, MA 02114 2696, USA
    Eur Respir J 36:569-76. 2010
  9. ncbi request reprint Impaired neuromuscular transmission after recovery of the train-of-four ratio
    M Eikermann
    Klinik für Anästhesiologie und Intensivmedizin, Universitatsklinikum Essen, Essen, Germany
    Acta Anaesthesiol Scand 51:226-34. 2007
  10. doi request reprint Neostigmine but not sugammadex impairs upper airway dilator muscle activity and breathing
    M Eikermann
    Division of Sleep Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA, USA
    Br J Anaesth 101:344-9. 2008

Collaborators

Detail Information

Publications33

  1. pmc The influence of aging on pharyngeal collapsibility during sleep
    Matthias Eikermann
    Department of Sleep Medicine, Brigham and Women s Hospital, Harvard Medical School, 75 Francis St, Boston, MA 02115, USA
    Chest 131:1702-9. 2007
    ..We tested the hypotheses that upper airway closing pressure (PCLOSE) and the increase in pharyngeal resistance during sleep (primary outcomes) as well as measures of arousal threshold (secondary outcomes) increase with age...
  2. ncbi request reprint Muscle force and fatigue in patients with sepsis and multiorgan failure
    M Eikermann
    Sleep Disorders Research Program, Brigham and Women s Hospital and Harvard Medical School, MA 02115, 75 Francis Street, Boston, MA 02115, USA
    Intensive Care Med 32:251-9. 2006
    ..Neuromuscular abnormalities are found frequently in sepsis and multiorgan failure (MOF). Surprisingly, however, there are no data on maximum skeletal muscle force and fatigue in these patients...
  3. ncbi request reprint Postoperative upper airway obstruction after recovery of the train of four ratio of the adductor pollicis muscle from neuromuscular blockade
    Matthias Eikermann
    Klinik für Anästhesiologie und Intensivmedizin, Universitatsklinikum Essen, Germany
    Anesth Analg 102:937-42. 2006
    ..9 predicts with high probability an absence of neuromuscular blocking drug-induced UAO, but outliers, i.e., persistent effects of neuromuscular blockade on upper airway integrity despite recovery of the TOF ratio, may still occur...
  4. ncbi request reprint The predisposition to inspiratory upper airway collapse during partial neuromuscular blockade
    Matthias Eikermann
    Oberarzt der Klinik für Anästhesiologie und Intensivmedizin, Universitatsklinikum Essen, Hufelandstrasse 55, D 45122 Essen, Germany
    Am J Respir Crit Care Med 175:9-15. 2007
    ....
  5. ncbi request reprint Preventive effects of perioperative parecoxib on post-discectomy pain
    G Riest
    Klinik für Anästhesiologie und Intensivmedizin, Universitaetsklinikum Essen, Germany
    Br J Anaesth 100:256-62. 2008
    ..Cyclooxygenase inhibitor treatment is viewed increasingly critical because of safety considerations, and there are several open questions on their optimal use...
  6. doi request reprint Development and longitudinal validation of the overall benefit of analgesia score: a simple multi-dimensional quality assessment instrument
    N Lehmann
    Institut für Medizinische Informatik, Biometrie und Epidemiologie, Universitat Duisburg Essen, Universitatsklinikum Essen, Essen, Germany
    Br J Anaesth 105:511-8. 2010
    ..The goal of this study was to develop and validate the overall benefit of analgesic score (OBAS), which assesses pain intensity and the opioid-related adverse effects...
  7. ncbi request reprint Incidence and duration of residual paralysis at the end of surgery after multiple administrations of cisatracurium and rocuronium
    D M Maybauer
    Klinik für Anästhesiologie und Intensivmedizin, Philipps Universitat Marburg, Germany
    Anaesthesia 62:12-7. 2007
    ....
  8. pmc Effects of pentobarbital on upper airway patency during sleep
    M Eikermann
    Dept of Anesthesia and Critical Care, Massachusetts General Hospital, 55 Fruit St, Boston, MA 02114 2696, USA
    Eur Respir J 36:569-76. 2010
    ..Pentobarbital did not affect the genioglossus negative-pressure reflex. Pentobarbital increases the time to arousal and stimulates genioglossus muscle activity, but it also increases upper airway resistance during sleep...
  9. ncbi request reprint Impaired neuromuscular transmission after recovery of the train-of-four ratio
    M Eikermann
    Klinik für Anästhesiologie und Intensivmedizin, Universitatsklinikum Essen, Essen, Germany
    Acta Anaesthesiol Scand 51:226-34. 2007
    ..It was speculated that patients may have impaired neuromuscular transmission after surgery of long duration, despite the recovery of the train-of-four (TOF) ratio...
  10. doi request reprint Neostigmine but not sugammadex impairs upper airway dilator muscle activity and breathing
    M Eikermann
    Division of Sleep Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA, USA
    Br J Anaesth 101:344-9. 2008
    ..Sugammadex reverses neuromuscular block by encapsulating rocuronium. However, its effects on upper airway integrity and breathing are unknown...
  11. doi request reprint Neostigmine/glycopyrrolate administered after recovery from neuromuscular block increases upper airway collapsibility by decreasing genioglossus muscle activity in response to negative pharyngeal pressure
    Frank Herbstreit
    Klinik für Anästhesiologie und Intensivmedizin, Universitatsklinikum Essen, Essen, Germany
    Anesthesiology 113:1280-8. 2010
    ..However, neostigmine may also impair muscle strength. We hypothesized that neostigmine administered after recovery of the train-of-four (TOF) ratio impairs upper airway integrity and genioglossus muscle function...
  12. ncbi request reprint Predictive value of mechanomyography and accelerometry for pulmonary function in partially paralyzed volunteers
    M Eikermann
    Klinik für Anästhesiologie und Intensivmedizin, Universitatsklinikum Essen, Essen, Germany
    Acta Anaesthesiol Scand 48:365-70. 2004
    ..During neuromuscular blockade we compared these methods and we assessed pulmonary function...
  13. doi request reprint Neuromuscular blocking agents for electroconvulsive therapy: a systematic review
    H Mirzakhani
    Department of Anaesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, USA
    Acta Anaesthesiol Scand 56:3-16. 2012
    ..Suxamethonium is commonly used, but nondepolarising NMBAs are indicated in patients with certain comorbidities. In this review, we summarise current concepts of NMBA management for ECT...
  14. doi request reprint Postoperative residual curarization from intermediate-acting neuromuscular blocking agents delays recovery room discharge
    A Butterly
    Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, 55 Fruit Street, Boston, MA 02114, USA
    Br J Anaesth 105:304-9. 2010
    ..9] is associated with increased morbidity and may delay postoperative recovery room (PACU) discharge. We tested the hypothesis that postoperative T4/T1 <0.9 increases PACU length of stay...
  15. pmc Genioglossus premotoneurons and the negative pressure reflex in rats
    Nancy L Chamberlin
    Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02115, USA
    J Physiol 579:515-26. 2007
    ..These results suggest that perihypoglossal GG premotoneurons near the obex mediate the NPR and those caudal to the obex are important mediators of respiratory-related GG activity but are not involved in the NPR...
  16. doi request reprint Impaired upper airway integrity by residual neuromuscular blockade: increased airway collapsibility and blunted genioglossus muscle activity in response to negative pharyngeal pressure
    Frank Herbstreit
    Oberarzt, Klinik für Anästhesiologie und Intensivmedizin, Universität Duisburg Essen and Universitätsklinikum Essen, Essen, Germany
    Anesthesiology 110:1253-60. 2009
    ..5-1) increases upper airway collapsibility and impairs upper airway dilator muscle compensatory responses to negative pharyngeal pressure challenges...
  17. pmc Airway dilator muscle activity and lung volume during stable breathing in obstructive sleep apnea
    Amy S Jordan
    Division of Sleep Medicine, Harvard Medical School, Boston, MA, USA
    Sleep 32:361-8. 2009
    ....
  18. ncbi request reprint Risk factors associated with bleeding during and after percutaneous dilational tracheostomy
    M Beiderlinden
    Klinik für Anästhesiologie und Intensivmedizin, Universitatsklinikum Essen, Essen, Germany
    Anaesthesia 62:342-6. 2007
    ..2-833.3); p = 0.01) and in the presence of two or more abnormal coagulation variables (OR 9.5 (95% CI 2.3-34.7); NNT 6.2 (95% CI 3.2-68); p = 0.002). Low-dose heparin treatment did not significantly increase the risk of chronic bleeding...
  19. pmc Pentobarbital dose-dependently increases respiratory genioglossus muscle activity while impairing diaphragmatic function in anesthetized rats
    Matthias Eikermann
    Department of Anesthesia and Critical Care, Massachusetts General Hospital, and Harvard Medical School, Boston, MA 02114 2696, USA
    Anesthesiology 110:1327-34. 2009
    ..The authors assessed the effects of pentobarbital on upper airway dilator and respiratory pump muscle function in rats and compared these results with the effects of normal sleep...
  20. ncbi request reprint Accelerometry of adductor pollicis muscle predicts recovery of respiratory function from neuromuscular blockade
    Matthias Eikermann
    Klinik für Anästhesiologie und Intensivmedizin, Universitatsklinikum Essen, Germany
    Anesthesiology 98:1333-7. 2003
    ....
  21. ncbi request reprint Emetic effects of morphine and piritramide
    C Breitfeld
    Klinik für Anästhesiologie und Intensivmedizin and Apotheke, Universitatsklinikum Essen, Hufelandstr 55, D 45122 Essen, Germany
    Br J Anaesth 91:218-23. 2003
    ..Thus, we tested the hypothesis that the incidence of vomiting and nausea differs between morphine and piritramide...
  22. pmc Influence of wakefulness on pharyngeal airway muscle activity
    Yu Lun Lo
    Brigham and Women s Hospital, Sleep Disorders Research Program, 75 Francis Street, Boston, Massachusetts 02115, USA
    Thorax 62:799-805. 2007
    ..A study was therefore undertaken to assess the isolated impact of sleep on upper airway muscle activity after minimising respiratory/mechanical inputs...
  23. pmc Unwarranted administration of acetylcholinesterase inhibitors can impair genioglossus and diaphragm muscle function
    Matthias Eikermann
    Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts 02114 2696, USA
    Anesthesiology 107:621-9. 2007
    ..The authors hypothesized that cholinesterase inhibition when given the in absence of neuromuscular blockade (NB) would decrease upper airway dilatory muscle activity and consequently upper airway volume...
  24. ncbi request reprint Optimal rocuronium dose for intubation during inhalation induction with sevoflurane in children
    M Eikermann
    Abteilung für Anästhesiologie und Intensivmedizin, Universitat Essen, Hufelandstr 55, D 45122 Essen, Germany
    Br J Anaesth 89:277-81. 2002
    ....
  25. doi request reprint Development and validation of a novel tool to estimate peri-operative blood loss
    D L Stahl
    Department of Anaesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Boston, USA
    Anaesthesia 67:479-86. 2012
    ..0001). Addition of the change in haemoglobin concentration improved the estimate for the 24- and 48-h postoperative Blood Loss Scores to explain 78% and 80% of the variance of measured blood loss...
  26. doi request reprint Differential effects of isoflurane and propofol on upper airway dilator muscle activity and breathing
    Matthias Eikermann
    Department of Anesthesia, Massachusetts General Hospital, and Harvard Medical School, Boston, Massachusetts 02114 2696, USA
    Anesthesiology 108:897-906. 2008
    ..The authors sought to understand which anesthetics increase or decrease upper airway dilator muscle activity and to study the mechanisms mediating the effect...
  27. doi request reprint Control of perioperative muscle strength during ambulatory surgery
    Paul H Alfille
    Department of Anesthesia and Critical Care, Massachusetts General Hospital, and Harvard Medical School, Boston, Massachusetts, USA
    Curr Opin Anaesthesiol 22:730-7. 2009
    ..This review describes strategies to control perioperative muscle strength in patients undergoing ambulatory surgery...
  28. doi request reprint Measurement of muscle strength in the intensive care unit
    Edward A Bittner
    Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA
    Crit Care Med 37:S321-30. 2009
    ..Stimulated (evoked) force of skeletal muscles, such as the adductor pollicis, can be assessed repetitively, independent of brain function, even in heavily sedated patients during high acuity of their disease...
  29. doi request reprint Increased sensitivity to a nondepolarizing muscle relaxant in a patient with acquired neuromyotonia
    Greg Ginsburg
    Department of Anesthesia and Critical Care, Massachusetts General Hospital, Shriners Hospital for Children Harvard Medical School, 55 Fruit Street, Boston, Massachusetts 02114, USA
    Muscle Nerve 40:139-42. 2009
    ....
  30. ncbi request reprint Fade of pulmonary function during residual neuromuscular blockade
    Matthias Eikermann
    Klinik für Anästhesiologie und Intensivmedizin, Universitatsklinikum Essen, Hufelandstr 55, D 45122 Essen, Germany
    Chest 127:1703-9. 2005
    ..We tested the hypothesis that fade of pulmonary function, ie, a decrease in values of FVC with the second spirometric maneuver compared to the first maneuver, occurs during impaired neuromuscular transmission...
  31. pmc Is brachial artery peak velocity variation ready for prime time?
    Matthias Eikermann
    Chest 131:1279-81. 2007
  32. ncbi request reprint Does fade with 100-Hz tetanic stimulation reliably detect residual neuromuscular blockade?
    Matthias Eikermann
    Anesth Analg 104:215; author reply 215-6. 2007
  33. doi request reprint Reversal of profound, high-dose rocuronium-induced neuromuscular blockade by sugammadex at two different time points: an international, multicenter, randomized, dose-finding, safety assessor-blinded, phase II trial
    Friedrich K Pühringer
    Department for Anesthesiology and Intensive Care Medicine, Klinikum am Steinenberg, Reutlingen, Germany
    Anesthesiology 109:188-97. 2008
    ..The efficacy and safety of sugammadex for the reversal of profound, high-dose rocuronium-induced neuromuscular blockade was evaluated...