Stefan Ehrlich

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. doi request reprint Promoter specific DNA methylation and gene expression of POMC in acutely underweight and recovered patients with anorexia nervosa
    Stefan Ehrlich
    Charite Universitatsmedizin Berlin, CVK, Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, Berlin, Germany
    J Psychiatr Res 44:827-33. 2010
  2. doi request reprint The 5-HTTLPR polymorphism, platelet serotonin transporter activity and platelet serotonin content in underweight and weight-recovered females with anorexia nervosa
    Stefan Ehrlich
    Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, Charite, Universitatsmedizin Berlin, CVK, Berlin, Germany
    Eur Arch Psychiatry Clin Neurosci 260:483-90. 2010
  3. doi request reprint Trajectories of agouti-related protein and leptin levels during antipsychotic-associated weight gain in patients with schizophrenia
    Stefan Ehrlich
    Translational Developmental Neuroscience Section, Department of Child and Adolescent Psychiatry, Dresden, Germany
    J Clin Psychopharmacol 32:767-72. 2012
  4. ncbi request reprint Smoking, but not malnutrition, influences promoter-specific DNA methylation of the proopiomelanocortin gene in patients with and without anorexia nervosa
    Stefan Ehrlich
    Dresden University of Technology, Department of Child and Adolescent Psychiatry, Translational Developmental Neuroscience Section, Dresden, Germany
    Can J Psychiatry 57:168-76. 2012
  5. pmc Associations of cortical thickness and cognition in patients with schizophrenia and healthy controls
    Stefan Ehrlich
    Psychiatric Neuroimaging Research Program, Massachusetts General Hospital Massachusetts Institute of Technology Harvard Medical School, Athinoula A Martinos Center for Biomedical Imaging, Charlestown, MA 02129 2000, USA
    Schizophr Bull 38:1050-62. 2012
  6. pmc The COMT Val108/158Met polymorphism and medial temporal lobe volumetry in patients with schizophrenia and healthy adults
    Stefan Ehrlich
    MGH MIT HMS Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA 02129 2000, USA
    Neuroimage 53:992-1000. 2010
  7. pmc Serum brain-derived neurotrophic factor and peripheral indicators of the serotonin system in underweight and weight-recovered adolescent girls and women with anorexia nervosa
    Stefan Ehrlich
    Department of Psychiatry and Psychotherapy, Charite Universitatsmedizin Berlin, Berlin, Germany
    J Psychiatry Neurosci 34:323-9. 2009
  8. doi request reprint The role of leptin and cortisol in hyperactivity in patients with acute and weight-recovered anorexia nervosa
    Stefan Ehrlich
    Charite Universitatsmedizin Berlin, Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, CVK, Augustenburger Platz 1, 13353 Berlin, Germany
    Prog Neuropsychopharmacol Biol Psychiatry 33:658-62. 2009
  9. doi request reprint S100B in underweight and weight-recovered patients with anorexia nervosa
    Stefan Ehrlich
    Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, Charite Universitatsmedizin Berlin, CVK, Augustenburger Platz 1, Berlin 13353, Germany
    Psychoneuroendocrinology 33:782-8. 2008
  10. doi request reprint Aromatic amino acids in weight-recovered females with anorexia nervosa
    Stefan Ehrlich
    Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, Charite Universitatsmedizin Berlin, Berlin, Germany
    Int J Eat Disord 42:166-72. 2009

Collaborators

Detail Information

Publications25

  1. doi request reprint Promoter specific DNA methylation and gene expression of POMC in acutely underweight and recovered patients with anorexia nervosa
    Stefan Ehrlich
    Charite Universitatsmedizin Berlin, CVK, Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, Berlin, Germany
    J Psychiatr Res 44:827-33. 2010
    ..This may represent a counterregulatory mechanism as part of the crosstalk between the immune and neuroendocrine systems...
  2. doi request reprint The 5-HTTLPR polymorphism, platelet serotonin transporter activity and platelet serotonin content in underweight and weight-recovered females with anorexia nervosa
    Stefan Ehrlich
    Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, Charite, Universitatsmedizin Berlin, CVK, Berlin, Germany
    Eur Arch Psychiatry Clin Neurosci 260:483-90. 2010
    ..Changes in platelet 5-HT transporter activity were related to the stage of the illness but not to 5-HTTLPR genotype. Increased V (max) and K (m) in recovered AN patients might mirror adaptive modulations of the 5-HT system...
  3. doi request reprint Trajectories of agouti-related protein and leptin levels during antipsychotic-associated weight gain in patients with schizophrenia
    Stefan Ehrlich
    Translational Developmental Neuroscience Section, Department of Child and Adolescent Psychiatry, Dresden, Germany
    J Clin Psychopharmacol 32:767-72. 2012
    ..The hypothalamic mediator Agouti-related protein (AGRP) is inhibited by leptin and was shown to increase food intake. The aim of the present study was to investigate the trajectory of AGRP levels during antipsychotic-induced weight gain...
  4. ncbi request reprint Smoking, but not malnutrition, influences promoter-specific DNA methylation of the proopiomelanocortin gene in patients with and without anorexia nervosa
    Stefan Ehrlich
    Dresden University of Technology, Department of Child and Adolescent Psychiatry, Translational Developmental Neuroscience Section, Dresden, Germany
    Can J Psychiatry 57:168-76. 2012
    ..Our pilot study evaluates the impact of environmental factors, such as nutrition and smoking status, on epigenetic patterns in a disease-associated gene...
  5. pmc Associations of cortical thickness and cognition in patients with schizophrenia and healthy controls
    Stefan Ehrlich
    Psychiatric Neuroimaging Research Program, Massachusetts General Hospital Massachusetts Institute of Technology Harvard Medical School, Athinoula A Martinos Center for Biomedical Imaging, Charlestown, MA 02129 2000, USA
    Schizophr Bull 38:1050-62. 2012
    ..In line with the prefrontal inefficiency hypothesis, schizophrenia patients may engage a larger compensatory network of brain regions other than frontal cortex to recall and manipulate verbal material in working memory...
  6. pmc The COMT Val108/158Met polymorphism and medial temporal lobe volumetry in patients with schizophrenia and healthy adults
    Stefan Ehrlich
    MGH MIT HMS Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA 02129 2000, USA
    Neuroimage 53:992-1000. 2010
    ..Taken together with previous work, our data support a model in which lower COMT activity, and a resulting elevation in extracellular dopamine levels, stimulates growth of medial temporal lobe structures...
  7. pmc Serum brain-derived neurotrophic factor and peripheral indicators of the serotonin system in underweight and weight-recovered adolescent girls and women with anorexia nervosa
    Stefan Ehrlich
    Department of Psychiatry and Psychotherapy, Charite Universitatsmedizin Berlin, Berlin, Germany
    J Psychiatry Neurosci 34:323-9. 2009
    ..To control for secondary effects of acute malnutrition, we assessed acutely underweight patients with anorexia nervosa (acAN) in comparison to long-term weight-recovered patients with the disorder (recAN) and healthy controls...
  8. doi request reprint The role of leptin and cortisol in hyperactivity in patients with acute and weight-recovered anorexia nervosa
    Stefan Ehrlich
    Charite Universitatsmedizin Berlin, Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, CVK, Augustenburger Platz 1, 13353 Berlin, Germany
    Prog Neuropsychopharmacol Biol Psychiatry 33:658-62. 2009
    ..In this study, we assessed the relationships between PA and both, cortisol and leptin levels at the same time in patients with acute anorexia nervosa (acAN) in comparison to recovered patients (recAN)...
  9. doi request reprint S100B in underweight and weight-recovered patients with anorexia nervosa
    Stefan Ehrlich
    Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, Charite Universitatsmedizin Berlin, CVK, Augustenburger Platz 1, Berlin 13353, Germany
    Psychoneuroendocrinology 33:782-8. 2008
    ..Together they do not support hypotheses comprising the degeneration of glial or neuronal cells to explain common signs of brain atrophy in patients with acute AN...
  10. doi request reprint Aromatic amino acids in weight-recovered females with anorexia nervosa
    Stefan Ehrlich
    Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, Charite Universitatsmedizin Berlin, Berlin, Germany
    Int J Eat Disord 42:166-72. 2009
    ..The present study assessed the availability of aromatic amino acids in the plasma of weight-recovered outpatients with AN (recAN) in comparison to acutely underweight AN patients (acAN) and healthy control woman (HCW)...
  11. doi request reprint Preproenkephalin expression in peripheral blood mononuclear cells of acutely underweight and recovered patients with anorexia nervosa
    Deike Weiss
    Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, Berlin, Berlin, Germany
    Neuropsychobiology 62:151-7. 2010
    ..We hypothesized that ppE expression in AN patients may vary depending on the state of the disorder and the extent of malnutrition...
  12. pmc DISC1 is associated with cortical thickness and neural efficiency
    Stefan Brauns
    MGH MIT HMS Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA 02129 2000, USA
    Neuroimage 57:1591-600. 2011
    ..Here, we investigated the effects of variation in DISC1 on cortical thickness. In a subsequent analysis we tested whether the identified DISC1 risk variant is also associated with neural activity during working memory functioning...
  13. doi request reprint Glial and neuronal damage markers in patients with anorexia nervosa
    Stefan Ehrlich
    Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, Charite, Universitatsmedizin Berlin, CVK, Augustenburger Platz 1, Berlin, Germany
    J Neural Transm 115:921-7. 2008
    ....
  14. doi request reprint Leptin and its associations with measures of psychopathology in patients with anorexia nervosa
    Stefan Ehrlich
    Department of Child and Adolescent Psychiatry, Universitatsmedizin Berlin, CVK, Augustenburger Platz 1, 13353, Berlin, Germany
    J Neural Transm 116:109-15. 2009
    ..e. the absence of sexual desire and intimate relationships. Our results are in accordance with recent animal experiments linking low leptin levels with decreased sexual interest irrespective of body weight...
  15. doi request reprint Correspondence between self-reported and parent-reported psychopathology in adolescents with eating disorders
    Harriet Salbach-Andrae
    Department of Child and Adolescent Psychiatry, Psychosomatic and Psychotherapy, Charite Universitatsmedizin Berlin, Campus Virchow Klinikum, Berlin, Germany
    Psychopathology 41:307-12. 2008
    ..This study examined parent/youth self-report agreement on emotional and behavioral symptoms among adolescents with eating disorders (ED)...
  16. doi request reprint Cognitive flexibility and Agouti-related protein in adolescent patients with anorexia nervosa
    Lea Sarrar
    Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, Charite Universitatsmedizin Berlin, Campus Virchow Klinikum, Berlin, Germany
    Psychoneuroendocrinology 36:1396-406. 2011
    ....
  17. pmc The impact of genome-wide supported schizophrenia risk variants in the neurogranin gene on brain structure and function
    Esther Walton
    Department of Child and Adolescent Psychiatry, University Hospital Carl Gustav Carus, Dresden University of Technology, Dresden, Germany
    PLoS ONE 8:e76815. 2013
    ....
  18. pmc Cumulative genetic risk and prefrontal activity in patients with schizophrenia
    Esther Walton
    MGH MIT HMS Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA, USA
    Schizophr Bull 39:703-11. 2013
    ..The GRS approach could provide an advantage over studying single genes in studies focusing on the genetic basis of polygenic conditions such as neuropsychiatric disorders...
  19. doi request reprint Genetic variation in GAD1 is associated with cortical thickness in the parahippocampal gyrus
    Stefan Brauns
    Department of Child and Adolescent Psychiatry, TU Dresden, Germany
    J Psychiatr Res 47:872-9. 2013
    ..Our findings point to the importance of the GABAergic system in the pathogenesis of schizophrenia...
  20. pmc The MCIC collection: a shared repository of multi-modal, multi-site brain image data from a clinical investigation of schizophrenia
    Randy L Gollub
    Department of Psychiatry, Massachusetts General Hospital, Building 120, Suite 101D, Charlestown, MA 02129 2000, USA
    Neuroinformatics 11:367-88. 2013
    ..This manuscript describes the inclusion/exclusion criteria, imaging parameters and other information that will assist those wishing to use this data repository. ..
  21. doi request reprint Neuroimaging as a potential biomarker to optimize psychiatric research and treatment
    Esther Walton
    Department of Child and Adolescent Psychiatry, University Hospital Carl Gustav Carus, Dresden University of Technology, Dresden, Germany
    Int Rev Psychiatry 25:619-31. 2013
    ..In the end, enhancing both our understanding of the pathophysiology of psychiatric disorders and the prediction of treatment success could eventually optimise current therapy plans...
  22. doi request reprint COMT Val108/158Met genotype modulates human sensory gating
    Tomislav Majic
    Clinic for Psychiatry and Psychotherapy, Charite University Medicine, Campus Mitte, Berlin, Germany
    Neuroimage 55:818-24. 2011
    ..It is however unclear if COMT genotype as a predictor of prefrontal efficiency modulates sensory gating on the level of the auditory cortex, i.e. the gating of the auditory evoked P50 and N100 components...
  23. doi request reprint Factitious disorder in children and adolescents: a retrospective study
    Stefan Ehrlich
    Charite Universitatsmedizin Berlin, Campus Virchow Klinikum, Klinik fur Psychiatrie, Psychosomatik, und Psychotherapie des Kindes und Jugendalters, Berlin, Germany
    Psychosomatics 49:392-8. 2008
    ..Factitious disorder (FD) presumably manifests at an early age, but epidemiological and clinical data about pediatric FD are still lacking...
  24. pmc Automated probabilistic reconstruction of white-matter pathways in health and disease using an atlas of the underlying anatomy
    Anastasia Yendiki
    Department of Radiology, Athinoula A Martinos Center for Biomedical Imaging, Massachusetts General Hospital and Harvard Medical School Boston, MA, USA
    Front Neuroinform 5:23. 2011
    ....
  25. doi request reprint Influence of age and movement complexity on kinematic hand movement parameters in childhood and adolescence
    Stefan Mark Rueckriegel
    Pediatric Neurooncology Program, Department of Pediatric Oncology and Hematology, Charite Universitatsmedizin Berlin, Augustenburger Platz 1, 13353 Berlin, Germany
    Int J Dev Neurosci 26:655-63. 2008
    ..Furthermore, differences were observed in the maturation of different task complexities, the complex fine motor function reaching maturity later than basic and repetitive movement patterns...