Research Topics
| JEANNE DUFFYSummaryAffiliation: Harvard University Country: USA Publications
Research Grants
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Detail Information
Publications
Association of intrinsic circadian period with morningness-eveningness, usual wake time, and circadian phaseJ F Duffy
Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, 02115, USA
Behav Neurosci 115:895-9. 2001..Circadian period was correlated with morningness-eveningness, circadian phase, and wake time, demonstrating that a fundamental property of the circadian pacemaker is correlated with the behavioral trait of morningness-eveningness...
Periodic limb movements in sleep exhibit a circadian rhythm that is maximal in the late evening/early nightJeanne F Duffy
Division of Sleep Medicine, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
Sleep Med 12:83-8. 2011..Our study aimed to determine whether this pattern is due to an endogenous circadian rhythm, like that in the related movement disorder Restless Legs Syndrome (RLS)...
Healthy older adults better tolerate sleep deprivation than young adultsJeanne F Duffy
Brigham and Women s Hospital General Clinical Research Center, Boston, Massachusetts, USA
J Am Geriatr Soc 57:1245-51. 2009..To determine whether healthy aging is associated with increased sleepiness and whether healthy older adults experience more sleepiness when acutely sleep deprived...
Decreased sensitivity to phase-delaying effects of moderate intensity light in older subjectsJeanne F Duffy
Division of Sleep Medicine, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
Neurobiol Aging 28:799-807. 2007..These findings suggest an age-related reduction in the phase-delaying response to moderate light levels. However, our findings alone do not explain the altered phase relationship between sleep and circadian rhythms associated with aging...
Entrainment of the human circadian system by lightJeanne F Duffy
Division of Sleep Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
J Biol Rhythms 20:326-38. 2005..We provide an integrated perspective on circadian entrainment in humans with respect to recent advances in our knowledge of circadian period and of the effects of light on the biological clock in humans...
Sex difference in the near-24-hour intrinsic period of the human circadian timing systemJeanne F Duffy
Division of Sleep Medicine, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
Proc Natl Acad Sci U S A 108:15602-8. 2011..0 h (35% vs. 14%; P < 0.01). The shorter average intrinsic circadian period observed in women may have implications for understanding sex differences in habitual sleep duration and insomnia prevalence...
Peak of circadian melatonin rhythm occurs later within the sleep of older subjectsJeanne F Duffy
Division of Sleep Medicine, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
Am J Physiol Endocrinol Metab 282:E297-303. 2002..In healthy older subjects, the relative timing of the melatonin rhythm with respect to sleep may not play a causal role in sleep disruption...
Age-related change in the relationship between circadian period, circadian phase, and diurnal preference in humansJeanne F Duffy
Division of Sleep Medicine, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
Neurosci Lett 318:117-20. 2002....
Getting through to circadian oscillators: why use constant routines?Jeanne F Duffy
Division of Sleep Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
J Biol Rhythms 17:4-13. 2002....
Sleep inertia varies with circadian phase and sleep stage in older adultsEdward J Silva
Division of Sleep Medicine, Brigham and Women s Hospital, Boston, MA 02115, USA
Behav Neurosci 122:928-35. 2008....
Exercise distributed across day and night does not alter circadian period in humansSean W Cain
Division of Sleep Medicine, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
J Biol Rhythms 22:534-41. 2007..Exercise distributed across biological day and night does not appear to affect circadian period...
Acute sleep deprivation and circadian misalignment associated with transition onto the first night of work impairs visual selective attentionNayantara Santhi
Division of Sleep Medicine, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, United States of America
PLoS ONE 2:e1233. 2007....
Plasma melatonin rhythms in young and older humans during sleep, sleep deprivation, and wakeJamie M Zeitzer
Department of Psychiatry, Stanford University, Palo Alto, CA 94304, USA
Sleep 30:1437-43. 2007..To determine the effects of sleep and sleep deprivation on plasma melatonin concentrations in humans and whether these effects are age-dependent...
Increased sleep disruption, reduced sleepiness in older subjects?Jeanne F Duffy
Sleep 28:1358-9. 2005
Sleep- and circadian-dependent modulation of REM densitySat Bir S Khalsa
Division of Sleep Medicine, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
J Sleep Res 11:53-9. 2002....
Scheduling of sleep/darkness affects the circadian phase of night shift workersNayantara Santhi
Division of Sleep Medicine, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, 221 Longwood Avenue, BL 438M, Boston, MA 02115, USA
Neurosci Lett 384:316-20. 2005..These results have applications to night shift workers, particularly in occupations in which alterations in the timing of light exposure cannot be achieved during working hours...
Temporal dynamics of late-night photic stimulation of the human circadian timing systemJamie M Zeitzer
Brigham and Women's Hosp, Boston, MA
Am J Physiol Regul Integr Comp Physiol 289:R839-44. 2005....
Intrinsic period and light intensity determine the phase relationship between melatonin and sleep in humansKenneth P Wright
Division of Sleep Medicine, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
J Biol Rhythms 20:168-77. 2005..This finding has important implications for understanding physiological organization by the brain's master circadian clock and may have implications for understanding mechanisms underlying circadian sleep disorders...
Older people awaken more frequently but fall back asleep at the same rate as younger peopleElizabeth B Klerman
Division of Sleep Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
Sleep 27:793-8. 2004....
Comparisons of the variability of three markers of the human circadian pacemakerElizabeth B Klerman
Division of Sleep Medicine, Brigham and Women s Hospital, Boston, MA 02115, USA
J Biol Rhythms 17:181-93. 2002....
Polysomnographic respiratory abnormalities in asymptomatic individualsMilena K Pavlova
Division of Sleep Medicine, Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
Sleep 31:241-8. 2008..We aimed to (1) define the frequency of respiratory disturbances (RDI: events per hour of sleep) during sleep in healthy individuals using current techniques and criteria and (2) determine how these abnormalities change with age and sex...
Research Grants
- Disrupted Sleep in the Elderly: Circadian EtiologyJEANNE DUFFY; Fiscal Year: 2009....
- Circadian & Genetic Evaluation of Extreme Sleep TimingJEANNE DUFFY; Fiscal Year: 2009..These data should provide better understanding of the chronobiologic and genetic basis of extreme diurnal preference, leading to better treatments for circadian rhythm sleep disorders. ..
- Circadian & Genetic Evaluation of Extreme Sleep TimingJEANNE DUFFY; Fiscal Year: 2009..These data should provide better understanding of the chronobiologic and genetic basis of extreme diurnal preference, leading to better treatments for circadian rhythm sleep disorders. ..
- Effect of Vitamin B12 on the Human Circadian PacemakerJEANNE DUFFY; Fiscal Year: 2007..abstract_text> ..
- DISRUPTED SLEEP IN THE ELDERLY--CIRCADIAN ETIOLOGYJEANNE DUFFY; Fiscal Year: 2002....
- Adaptation of circadian responses to light treatmentJeanne F Duffy; Fiscal Year: 2010..The understanding of the effects of prior photic history could help explain the ability of the circadian system to adapt to changes in natural outside light intensities across the seasons and at different latitudes. ..
