Iain DrummondSummaryAffiliation: Harvard University Country: USA Publications
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Publications
Making a zebrafish kidney: a tale of two tubesIain Drummond
Department of Medicine, Harvard Medical School and Renal Unit, Massachusetts General Hospital, 149 13th Street, Charlestown, MA 02129, USA
Trends Cell Biol 13:357-65. 2003....
Acute renal failure in zebrafish: a novel system to study a complex diseaseDirk M Hentschel
Department of Medicine, Renal Division, Brigham and Women's Hospital, Boston, MA 02115, USA
Am J Physiol Renal Physiol 288:F923-9. 2005..Therefore, zebrafish provides a unique model system, amenable to genetic manipulation and drug screening, to explore the pathophysiology of ARF and establish novel therapies with potential use in mammals...
Studying cilia in zebrafishIain Drummond
Department of Medicine, Harvard Medical School and Massachusetts General Hospital, Charlestown, Massachusetts 02129, USA
Methods Cell Biol 93:197-217. 2009....
The centrosomal protein nephrocystin-6 is mutated in Joubert syndrome and activates transcription factor ATF4John A Sayer
Department of Pediatrics, University of Michigan, Ann Arbor, Michigan 48109, USA
Nat Genet 38:674-81. 2006..Our findings help establish the link between centrosome function, tissue architecture and transcriptional control in the pathogenesis of cystic kidney disease, retinal degeneration, and central nervous system development...
Positional cloning uncovers mutations in PLCE1 responsible for a nephrotic syndrome variant that may be reversibleBernward Hinkes
Department of Pediatrics, University of Michigan, Ann Arbor, Michigan 48109, USA
Nat Genet 38:1397-405. 2006..These findings, together with the zebrafish model of human nephrotic syndrome generated by plce1 knockdown, open new inroads into pathophysiology and treatment mechanisms of nephrotic syndrome...
The homodimeric kinesin, Kif17, is essential for vertebrate photoreceptor sensory outer segment developmentChristine Insinna
Department of Cell Biology, Neurobiology and Anatomy, Medical College of Wisconsin, 8701 Watertown Plank Rd, Milwaukee, WI 53226, USA
Dev Biol 316:160-70. 2008..Our analysis shows that Kif17 is essential for photoreceptor OS development, and suggests that Kif17 plays a cell type specific role in vertebrate ciliogenesis...
