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Species | L DjousseSummaryAffiliation: Harvard University Country: USA Publications
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Publications
Fatty acid-binding protein 4 and incident heart failure: the Cardiovascular Health StudyLuc Djousse
Division of Aging, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, and Boston Veterans Affairs Healthcare System, Boston, MA 02120, USA
Eur J Heart Fail 15:394-9. 2013..To examine the association of plasma fatty acid-binding protein 4 (FABP4) with incident heart failure...
Association between modifiable lifestyle factors and residual lifetime risk of diabetesL Djousse
Divisions of Aging, Boston, MA, USA Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA, USA Massachusetts Veterans Epidemiology and Research Information Center and Geriatric Research, Education and Clinical Center, Boston Veterans Affairs Healthcare System, Boston, MA, USA Electronic address
Nutr Metab Cardiovasc Dis 23:17-22. 2013..We sought to examine the association between modifiable lifestyle factors and residual lifetime risk of diabetes...- Plasma phospholipid concentration of cis-palmitoleic acid and risk of heart failureLuc Djousse
Division of Aging, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02120, USA
Circ Heart Fail 5:703-9. 2012..We assessed whether plasma phospholipid cis-palmitoleic acid was associated with heart failure risk... - Fish consumption, omega-3 fatty acids and risk of heart failure: a meta-analysisLuc Djousse
Division of Aging, Department of Medicine, Brigham and Women s Hospital, Boston, MA 02120, USA
Clin Nutr 31:846-53. 2012..We systematically reviewed the evidence on the association of omega-3 fatty acids and fish intake with the incidence of heart failure in this meta-analysis... - Adiposity and incident heart failure in older adults: the cardiovascular health studyLuc Djousse
Division of Aging, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts, USA
Obesity (Silver Spring) 20:1936-41. 2012..09 (95% CI: 0.99-1.21)). In conclusion, a higher WC is associated with an increased risk of HF independent of BMI in community-living older men and women... - Red blood cell membrane concentration of cis-palmitoleic and cis-vaccenic acids and risk of coronary heart diseaseLuc Djousse
Division of Aging, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts, USA
Am J Cardiol 110:539-44. 2012..69 to 0.91, per SD increase). In conclusion, our data showed a positive association between RBC membrane cis-palmitoleic acid and CHD risk in male physicians. Furthermore, RBC membrane cis-vaccenic acid was inversely related to CHD... - Plasma fatty acid-binding protein 4, nonesterified fatty acids, and incident diabetes in older adultsLuc Djousse
Division of Aging, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts, USA
Diabetes Care 35:1701-7. 2012..To examine the relation of fatty acid-binding protein (FABP)4 and nonesterified fatty acids (NEFAs) to diabetes in older adults... - Nonesterified fatty acids and risk of sudden cardiac death in older adultsLuc Djousse
Division of Aging, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School and Boston Veterans Affairs Healthcare System, Boston, MA 02120, USA
Circ Arrhythm Electrophysiol 5:273-8. 2012..Although nonesterified fatty acids (NEFA) have been positively associated with coronary heart disease risk factors, limited and inconsistent data are available on the relation between NEFA and sudden cardiac death... - Do inflammation and procoagulation biomarkers contribute to the metabolic syndrome cluster?Aldi T Kraja
Division of Statistical Genomics, Washington University School of Medicine, Saint Louis, MO, USA
Nutr Metab (Lond) 4:28. 2007..However, the relationship of inflammatory biomarkers to MetS is not clear... - Alcohol consumption, physical activity, and chronic disease risk factors: a population-based cross-sectional surveyKenneth J Mukamal
Division of General Medicine and Primary Care, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts, USA
BMC Public Health 6:118. 2006..Whether the association of alcohol consumption and cardiovascular disease is the product of confounding and the degree to which this concern applies to other behaviors are unclear... - Genetic analysis of the GRIK2 modifier effect in Huntington's diseaseWenqi Zeng
Molecular Neurogenetics Unit, Center for Human Genetic Research, Massachusetts General Hospital, 185 Cambridge Street, Boston, MA 02114, USA
BMC Neurosci 7:62. 2006.... - Egg consumption in relation to cardiovascular disease and mortality: the Physicians' Health StudyLuc Djousse
Division of Aging, Brigham and Women s Hospital and Harvard Medical School, 1620 Tremont Street, 3rd Floor, Boston MA 02120, USA
Am J Clin Nutr 87:964-9. 2008..Although eggs are important sources of cholesterol and other nutrients, limited and inconsistent data are available on the effects of egg consumption on the risk of CVD and mortality... - Egg consumption and risk of heart failure in the Physicians' Health StudyLuc Djousse
Division of Aging, Brigham and Women s Hospital and Harvard Medical School, 1620 Tremont St, Third Floor, Boston MA 02120, USA
Circulation 117:512-6. 2008..Although eggs are important sources of dietary cholesterol and other nutrients, little is known about the association between egg consumption and heart failure (HF) risk... - Alcohol consumption and heart failure in hypertensive US male physiciansLuc Djousse
Division of Aging, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts, USA
Am J Cardiol 102:593-7. 2008..In conclusion, our data suggested that light to moderate alcohol consumption was associated with a lower risk of HF in hypertensive male physicians... - Alcohol consumption and heart failure: a systematic reviewLuc Djousse
Division of Aging, Brigham and Women s Hospital, Harvard Medical School, 1620 Tremont Street, 3rd Floor, Boston, MA 02120, USA
Curr Atheroscler Rep 10:117-20. 2008..This article reviews current evidence on the association between alcohol consumption and HF... - Relation of albuminuria to left ventricular mass (from the HyperGEN Study)Luc Djousse
Division of Aging, Department of Medicine, Brigham and Women s Hospital, Boston, Massachusetts, USA
Am J Cardiol 101:212-6. 2008..In conclusion, these results suggest that albuminuria is positively associated with LV mass in normotensive subjects as it is in hypertensive subjects... 
Alcohol consumption and plasma atrial natriuretic peptide (from the HyperGEN study)Luc Djousse
Division of Aging, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts, USA
Am J Cardiol 98:628-32. 2006..0001 each for trend). In conclusion, our data have shown a positive and linear association between alcohol consumption and ANP in men and women, irrespective of race...- Cystatin C and risk of heart failure in the Physicians' Health Study (PHS)Luc Djousse
Department of Medicine, Division of Aging, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02120, USA
Am Heart J 155:82-6. 2008..Chronic kidney disease is a risk factor for heart failure (HF). Although cystatin C can detect early kidney dysfunction, limited data are available on the association between cystatin C and HF... - Secular trends of heart failure among US male physiciansLuc Djousse
Division of Aging, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02120, USA
Am Heart J 154:855-60. 2007..Heart failure (HF) remains a major public health issue. Data on long-term trends in the incidence of HF and survival after its onset are limited... - Breakfast cereals and risk of heart failure in the physicians' health study ILuc Djousse
Division of Aging, Brigham and Women s Hospital and Harvard Medical School, 1620 Tremont St, Third Floor, Boston, MA 02120, USA
Arch Intern Med 167:2080-5. 2007..Consumption of grain products and dietary fiber has been shown to reduce the risk of hypertension and myocardial infarction. However, it is not known whether a higher consumption of breakfast cereals is associated with risk of HF... - Nut consumption and risk of hypertension in US male physiciansLuc Djousse
Division of Aging, Department of Medicine, Brigham and Women s Hospital, Boston, MA 02120, USA
Clin Nutr 28:10-4. 2009..Hypertension is a risk factor for cardiovascular disease and dietary factors may play an important role in its prevention. We sought to examine the association between nut consumption and incident hypertension... - Nut consumption and risk of heart failure in the Physicians' Health Study ILuc Djousse
Division of Aging and Preventive Medicine, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02120, USA
Am J Clin Nutr 88:930-3. 2008.... - Plasma omega-3 fatty acids and incident diabetes in older adultsLuc Djousse
Division of Aging, Department of Epidemiology, University of Washington, Seattle, WA, USA
Am J Clin Nutr 94:527-33. 2011.... - Dietary omega-3 fatty acids and fish consumption and risk of type 2 diabetesLuc Djousse
Division of Aging and Preventive Medicine, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA, USA
Am J Clin Nutr 93:143-50. 2011..Although dietary omega-3 (n-3) fatty acids may confer some cardiovascular benefits, it is unclear whether these nutrients may also unfavorably affect risk of type 2 diabetes (T2D)... - Chocolate consumption is inversely associated with prevalent coronary heart disease: the National Heart, Lung, and Blood Institute Family Heart StudyLuc Djousse
Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston 02120, MA, USA
Clin Nutr 30:182-7. 2011..However, limited data are available on the association of chocolate consumption and the risk of coronary heart disease (CHD). We sought to examine the association between chocolate consumption and prevalent CHD... - Egg consumption and risk of type 2 diabetes in older adultsLuc Djousse
Division of Aging, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02120, USA
Am J Clin Nutr 92:422-7. 2010..Type 2 diabetes (T2D) remains an important public health issue in the United States. There are limited and inconsistent data on the association between egg consumption and fasting glucose or incident diabetes... - Nut consumption and risk of stroke in US male physiciansLuc Djousse
Division of Aging, Department of Medicine, Brigham and Women s Hospital, Boston, MA 02120, USA
Clin Nutr 29:605-9. 2010..We sought to examine whether nut consumption is associated with total and subtypes of stroke... - Diet and metabolic syndromeL Djousse
Division of Aging, Department of Medicine, Brigham and Women s Hospital, Boston, MA 02120, USA
Endocr Metab Immune Disord Drug Targets 10:124-37. 2010..This manuscript reviews current evidence on dietary patterns, consumption of fat, whole grains, carbohydrate quality and quantity, and moderate alcohol consumption as they relate to metabolic syndrome... - Dietary cholesterol and coronary artery disease: a systematic reviewLuc Djousse
Division of Aging, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, 3rd Floor, Boston, MA 02120, USA
Curr Atheroscler Rep 11:418-22. 2009..This article reviews the current evidence on the association between dietary cholesterol and the risk of CHD... - Apolipoprotein e, alcohol consumption, and risk of ischemic stroke: the Framingham Heart Study revisitedLuc Djousse
Division of Aging, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts 02120, USA
J Stroke Cerebrovasc Dis 18:384-8. 2009..We sought to examine whether epsilon(4) allele of the apoE gene influences the association between alcohol consumption and ischemic stroke or high-density lipoprotein (HDL) cholesterol... - Relation between modifiable lifestyle factors and lifetime risk of heart failureLuc Djousse
Division of Aging, Brigham and Women s Hospital and Harvard Medical School, 1620 Tremont St, Third Floor, Boston, MA 02120, USA
JAMA 302:394-400. 2009..The lifetime risk of heart failure at age 40 years is approximately 1 in 5 in the general population; however, little is known about the association between modifiable lifestyle factors and the remaining lifetime risk of heart failure... - Alcohol consumption and risk of cardiovascular disease and death in women: potential mediating mechanismsLuc Djousse
Division of Aging, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02120, USA
Circulation 120:237-44. 2009..We examined the association between alcohol and CVD and death in 26 399 women and estimated the proportion of reduced risk of CVD/death explained by a series of intermediate factors... - Parental history of myocardial infarction and risk of heart failure in male physiciansL Djousse
Division of Aging, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02120, USA
Eur J Clin Invest 38:896-901. 2008..Although heart failure (HF) remains a major public health issue, limited data are available on the utility of parental information on the risk of HF in offspring... - Egg consumption and risk of type 2 diabetes in men and womenLuc Djousse
Division of Aging, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
Diabetes Care 32:295-300. 2009..This project sought to examine the relation between egg intake and the risk of type 2 diabetes in two large prospective cohorts... - Alcohol consumption and type 2 diabetes among older adults: the Cardiovascular Health StudyLuc Djousse
Division of Aging, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, 1620 Tremont St, 3rd Floor, Boston, MA 02120, USA
Obesity (Silver Spring) 15:1758-65. 2007..The objective was to examine the role of total and beverage-specific alcohol consumption on the incidence of type 2 diabetes mellitus (DM) among elderly men and women... - Fucosyltransferase 3 polymorphism and atherothrombotic disease in the Framingham Offspring StudyLuc Djousse
Division of Aging, Brigham and Women s Hospital and Harvard Medical School, Boston, MA, USA
Am Heart J 153:636-9. 2007..Previous studies have suggested a positive association between phenotypes of fucosyltransferase 3 (FUT3) gene (also known as Lewis gene) and coronary heart disease... - Alcohol consumption and risk of heart failure in the Physicians' Health Study ILuc Djousse
Division of Aging, Brigham and Women s Hospital and Harvard Medical School, 1620 Tremont St, 3rd Floor, Boston MA 02120, USA
Circulation 115:34-9. 2007..Data on the effects of moderate alcohol consumption on the risk of HF have been sparse and inconsistent. This study sought to evaluate the association between moderate alcohol consumption and incident HF... - Dietary linolenic acid and fasting glucose and insulin: the National Heart, Lung, and Blood Institute Family Heart StudyLuc Djousse
Division of Aging, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02120, USA
Obesity (Silver Spring) 14:295-300. 2006..To assess whether dietary linolenic acid is associated with fasting insulin and glucose... - Influence of saturated fat and linolenic acid on the association between intake of dairy products and blood pressureLuc Djousse
Division of Aging, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02120, USA
Hypertension 48:335-41. 2006..This suggests that consumption of low-fat dairy products might be more beneficial for preventing HTN... - Influence of alcohol dehydrogenase 1C polymorphism on the alcohol-cardiovascular disease association (from the Framingham Offspring Study)Luc Djousse
Section of Preventive Medicine and Epidemiology, Evans Department of Medicine, Boston University, Boston, MA, USA
Am J Cardiol 96:227-32. 2005..The interaction does not appear to be mediated through effects on high-density lipoprotein cholesterol... - Nut consumption and risk of atrial fibrillation in the Physicians' Health StudyO Khawaja
Harvard Medical School, Boston, MA, USA
Nutr J 11:17. 2012..3 million people in USA and 4.5 million people in European Union. The aim of the study was to examine the association between nut consumption and incident atrial fibrillation... - Relation of alcohol consumption and coronary heart disease in hypertensive male physicians (from the Physicians' Health Study)Kathryn A Britton
Harvard Medical School, Massachusetts Veterans Epidemiology and Research Information Center MAVERIC, Boston Veterans Affairs Healthcare System, Boston, MA, USA
Am J Cardiol 104:932-5. 2009..In conclusion, our data demonstrated an inverse relation between moderate alcohol consumption and CHD in hypertensive men... - Alcohol consumption and metabolic syndrome: does the type of beverage matter?Luc Djousse
Boston University School of Medicine, Room B 612, 715 Albany Street, Boston, Massachusetts 02118, USA
Obes Res 12:1375-85. 2004..To examine the association between total and beverage-specific alcohol consumption and the prevalence odds of metabolic syndrome (MS)... - Influence of apolipoprotein E, smoking, and alcohol intake on carotid atherosclerosis: National Heart, Lung, and Blood Institute Family Heart StudyLuc Djousse
Section of Preventive Medicine and Epidemiology, Evans Department of Medicine, Boston University School of Medicine, Boston, Mass 02118, USA
Stroke 33:1357-61. 2002..Apolipoprotein E (apoE) isoforms and lifestyle factors play an important role in the development of coronary heart disease. The association of apoE and carotid atherosclerosis remains controversial... - Weight loss in early stage of Huntington's diseaseL Djousse
Evans Department of Medicine, Section of Preventive Medicine and Epidemiology, Boston University School of Medicine, Boston, MA 02118, USA
Neurology 59:1325-30. 2002..In transgenic mouse models of HD, weight loss is recognized as a feature associated with the disease onset. It is unclear whether a similar pattern occurs in humans... - Nut consumption and risk of type II diabetes in the Physicians' Health StudyJ Kochar
Department of Medicine, Medical College of Wisconsin, Milwaukee, WI, USA
Eur J Clin Nutr 64:75-9. 2010..We sought to examine the association between nut consumption and the risk of DM... - Lack of association between the angiotensin-converting enzyme insertion/deletion polymorphism and plasminogen activator inhibitor-1 antigen levels in the National Heart, Lung, and Blood Institute Family Heart StudyJ S Pankow
Department of Epidemiology, School of Public Health, University of North Carolina at Chapel Hill, 27514, USA
Blood Coagul Fibrinolysis 11:551-8. 2000..Our findings suggest that the ACE insertion/deletion polymorphism has relatively little, if any, influence on circulating PAI-1 levels in the population at large... - Glycemic index, glycemic load, and cereal fiber intake and risk of type 2 diabetes in US black womenSupriya Krishnan
Slone Epidemiology Center, Boston, MA 02215, USA
Arch Intern Med 167:2304-9. 2007..Previous studies of carbohydrate quality and risk of type 2 diabetes mellitus have yielded inconsistent findings. Because diet is in part culturally determined, a study of dietary factors in US black women is of interest... - Serum albumin and risk of myocardial infarction and all-cause mortality in the Framingham Offspring StudyLuc Djousse
Department of Medicine, Boston University School of Medicine, Boston, Mass 02118, USA
Circulation 106:2919-24. 2002.... - Evidence for major genes influencing pulmonary function in the NHLBI family heart studyJ B Wilk
Section of Preventive Medicine and Epidemiology, Boston University School of Medicine, Boston, Massachusetts 02118, USA
Genet Epidemiol 19:81-94. 2000..These results support the hypothesis that complex relationships exist for lung function traits and that multiple genes and environmental factors influence lung function... - Alcohol consumption and risk of lung cancer: the Framingham StudyLuc Djousse
Section of Preventive Medicine and Epidemiology, Evans Department of Medicine, Boston University School of Medicine, Boston, MA 02118, USA
J Natl Cancer Inst 94:1877-82. 2002..Reports on the association between alcohol consumption and the risk of lung cancer have been inconsistent. The purpose of this study was to assess this association in a cohort study... - Dietary linolenic acid is inversely associated with plasma triacylglycerol: the National Heart, Lung, and Blood Institute Family Heart StudyLuc Djousse
Section of Preventive Medicine and Epidemiology, Evans Department of Medicine, Boston University School of Medicine, Room B 612, 715 Albany Street, Boston, MA 02118, USA
Am J Clin Nutr 78:1098-102. 2003..Dietary intake of linolenic acid is associated with a decreased risk of cardiovascular disease mortality. However, the mechanisms by which dietary linolenic acid affects cardiovascular disease risk are not clearly understood... - Red meat consumption and risk of heart failure in male physiciansA Ashaye
Boston University School of Public Health, Boston, MA, USA
Nutr Metab Cardiovasc Dis 21:941-6. 2011..However, it is not known whether red meat intake influences the risk of HF. We therefore examined the association between red meat consumption and incident HF... - Effects of cocoa products/dark chocolate on serum lipids: a meta-analysisO A Tokede
Division of Aging, Department of Medicine, Brigham and Women s Hospital, Boston, MA 02120 1613, USA
Eur J Clin Nutr 65:879-86. 2011..06 mg/dl (-13.45 to 3.32 mg/dl)). These data are consistent with beneficial effects of dark chocolate/cocoa products on total and LDL cholesterol and no major effects on HDL and TG in short-term intervention trials... - Relation between dietary linolenic acid and coronary artery disease in the National Heart, Lung, and Blood Institute Family Heart StudyL Djousse
Section of Preventive Medicine and Epidemiology, Evans Department of Medicine, The School of Medicine, Boston University, Boston, MA 02118, USA
Am J Clin Nutr 74:612-9. 2001..Studies in humans and animals also reported an inverse association between alpha-linolenic acid and cardiovascular disease morbidity and mortality... - Alcohol consumption and risk of intermittent claudication in the Framingham Heart StudyL Djousse
Department of Medicine, Section of Preventive Medicine and Epidemiology Boston University School of Medicine, Boston, Massachusetts, USA
Circulation 102:3092-7. 2000..The purpose of this study was to assess the relation of alcohol consumption and type of beverage to the development of IC among participants in the Framingham Heart Study... - Effect of serum albumin and bilirubin on the risk of myocardial infarction (the Framingham Offspring Study)Luc Djousse
The Department of Medicine, Section of Preventive Medicine and Epidemiology, Boston University School of Medicine, Boston, Massachusetts 02118, USA
Am J Cardiol 91:485-8. 2003 - Normal systolic blood pressure and risk of heart failure in US male physiciansKathryn A Britton
Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
Eur J Heart Fail 11:1129-34. 2009..However, limited data are available on the relationship between normotensive SBP and the risk of HF... - Change in high-density lipoprotein cholesterol and incident coronary heart disease in apparently healthy male physiciansCatherine Rahilly-Tierney
Massachusetts Veterans Epidemiology and Research Information Center, Office of Research and Development, Department of Veterans Affairs, Boston, Massachusetts, USA
Am J Cardiol 102:1663-7. 2008..43 (95% CI 0.23 to 0.83) for subjects with an HDL cholesterol increase >or=12.5 mg/dl. In conclusion, our findings were consistent with an inverse graded relation between 14-year increase in HDL cholesterol and risk of subsequent CHD... - Lifestyle risk factors and new-onset diabetes mellitus in older adults: the cardiovascular health studyDariush Mozaffarian
Divisions of Cardiovascular Medicine, Department of Medicine, Brigham and Women s Hospital, Harvard School of Public Health, 665 Huntington Ave, Bldg 2 319, Boston, MA 02115, USA
Arch Intern Med 169:798-807. 2009..The objective of this study was to determine how lifestyle factors, assessed in combination, relate to new-onset diabetes in a broad and relatively unselected population of older adults... - Physical activity and weight gain preventionI Min Lee
Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02215, USA
JAMA 303:1173-9. 2010..In 2008, federal guidelines recommended at least 150 minutes per week (7.5 metabolic equivalent [MET] hours per week) of moderate-intensity activity for "substantial health benefits.".. - Intake of fruits, vegetables, and dairy products in early childhood and subsequent blood pressure changeLynn L Moore
Section of Preventive Medicine and Epidemiology, Boston University School of Medicine, Boston, Massachusetts 02118, USA
Epidemiology 16:4-11. 2005..Diets characterized by high intakes of fruits and vegetables and low-fat dairy products (for example, the DASH diet) have been shown to reduce blood pressure in adults. The effects of similar diets on children's blood pressure are unknown... - Alcohol consumption and the risk of bladder cancer in the Framingham Heart StudyLuc Djousse
Preventive Medicine and Epidemiology Section, Evans Department of Medicine, Boston University School of Medicine, Rm B 612, 715 Albany St, Boston, MA 02118, USA
J Natl Cancer Inst 96:1397-400. 2004..03), whereas wine (P(trend) =.7) and spirit (P(trend) =.2) consumption were not. Our data suggest that total and beverage-specific alcohol consumption are not associated with an increased risk of bladder cancer... - Transferability and fine-mapping of glucose and insulin quantitative trait loci across populations: CARe, the Candidate Gene Association ResourceC T Liu
Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA
Diabetologia 55:2970-84. 2012..We tested the transferability of 18 single-nucleotide polymorphisms (SNPs) associated with glycaemic traits identified in European ancestry (EuA) populations in 5,984 non-diabetic AfAs... - Acute effects of a high-fat meal with and without red wine on endothelial function in healthy subjectsL Djousse
Section of Preventive Medicine and Epidemiology, Evans Memorial Department of Medicine, Boston University School of Medicine, Massachusetts, USA
Am J Cardiol 84:660-4. 1999..Under these conditions, we did not demonstrate a beneficial acute effect of red wine on endothelial function... - Breakfast cereals and risk of type 2 diabetes in the Physicians' Health Study IJinesh Kochar
Division of Aging, Brigham and Women s Hospital and Harvard Medical School, 1620 Tremont Street, 3rd Floor, Boston MA 02120, USA
Obesity (Silver Spring) 15:3039-44. 2007..To examine the association between breakfast cereal consumption and the risk of type 2 diabetes (DM)... - Incidence of cardiovascular disease and cancer in advanced age: prospective cohort studyJane A Driver
Division of Aging, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02215, USA
BMJ 337:a2467. 2008..To investigate the influence of increasing age on the incidence and remaining lifetime risk of cardiovascular disease and cancer in a cohort of older men... - Exceptional longevity in men: modifiable factors associated with survival and function to age 90 yearsLaurel B Yates
Division of Aging, Brigham and Women s Hospital, 1620 Tremont St, Boston, MA 02120, USA
Arch Intern Med 168:284-90. 2008..We examined modifiable factors associated with a life span of 90 or more years and late-life function in men... - Dietary linolenic acid and adjusted QT and JT intervals in the National Heart, Lung, and Blood Institute Family Heart studyLuc Djousse
Section of Preventive Medicine and Epidemiology, Evans Department of Medicine, Boston University School of Medicine, Boston, Massachusetts 02118, USA
J Am Coll Cardiol 45:1716-22. 2005..The goal of this study was to examine whether higher consumption of total linolenic acid was associated with rate-adjusted QT and JT intervals (QTrr and JTrr, respectively)... - Interaction of normal and expanded CAG repeat sizes influences age at onset of Huntington diseaseL Djousse
Section of Preventive Medicine and Epidemiology, Boston University School of Medicine, Boston, Massachusetts 02118, USA
Am J Med Genet A 119:279-82. 2003..These findings suggest that an increase in the size of the normal repeat may mitigate the expression of the disease among HD affected persons with large expanded CAG repeats... - Is alcohol consumption associated with calcified atherosclerotic plaque in the coronary arteries and aorta?R Curtis Ellison
Section of Preventive Medicine and Epidemiology, Boston University School of Medicine, Boston, MA 02118, USA
Am Heart J 152:177-82. 2006..Previous results have been conflicting, showing increases, decreases, or no effect of alcohol on risk of calcified plaque... - A genome-wide scan of pulmonary function measures in the National Heart, Lung, and Blood Institute Family Heart StudyJemma B Wilk
Boston University School of Medicine, B 601, 715 Albany Street, Boston, MA 02118, USA
Am J Respir Crit Care Med 167:1528-33. 2003..0. FEV1 and FVC were suggestively linked to regions on chromosome 18 with multipoint LOD scores of 2.4 for FEV1 and 1.5 for FVC at 31 cM (D18S843) and a LOD of 2.9 for FVC at 79 cM (D18S858)... - Overall and central obesity and risk of type 2 diabetes in U.S. black womenSupriya Krishnan
Slone Epidemiology Center, 1010, Commonwealth Avenue, Fourth Floor, Boston, MA 02215, USA
Obesity (Silver Spring) 15:1860-6. 2007..We examined the association of BMI, abdominal obesity, and weight gain with risk of type 2 diabetes... - Dietary linolenic acid is inversely associated with calcified atherosclerotic plaque in the coronary arteries: the National Heart, Lung, and Blood Institute Family Heart StudyLuc Djousse
Evans Department of Medicine, Section of Preventive Medicine and Epidemiology, Boston University School of Medicine, Boston, Mass 02118, USA
Circulation 111:2921-6. 2005..High dietary intake of linolenic acid is associated with a lower risk of cardiovascular disease mortality. However, little is known about the association between linolenic acid and subclinical atherosclerosis... - Fruit and vegetable consumption and LDL cholesterol: the National Heart, Lung, and Blood Institute Family Heart StudyLuc Djousse
Section of Preventive Medicine and Epidemiology, Evans Department of Medicine, Boston University School of Medicine, Boston, MA 02118, USA
Am J Clin Nutr 79:213-7. 2004..An elevated LDL-cholesterol concentration is associated with an increased risk of cardiovascular disease. The association between fruit and vegetable consumption and LDL has been inconsistent... - Prediction and classification of cardiovascular disease risk in older adults with diabetesK J Mukamal
Division of General Medicine and Primary Care, Beth Israel Deaconess Medical Center, 1309 Beacon Street, Brookline, MA 02446, USA
Diabetologia 56:275-83. 2013..We sought to derive and validate a cardiovascular disease (CVD) prediction algorithm for older adults with diabetes, and evaluate the incremental benefit of adding novel circulating biomarkers and measures of subclinical atherosclerosis... - Genome-wide linkage analyses for age at diagnosis of hypertension and early-onset hypertension in the HyperGEN studyJemma B Wilk
Boston University School of Medicine, Boston, Massachusetts 02118, USA
Am J Hypertens 17:839-44. 2004.... - Genome-wide significance for a modifier of age at neurological onset in Huntington's disease at 6q23-24: the HD MAPS studyJian Liang Li
Department of Neurology, Boston University School of Medicine, Boston, MA, USA
BMC Med Genet 7:71. 2006.... - Long-term alcohol consumption and the risk of atrial fibrillation in the Framingham StudyLuc Djousse
Section of Preventive Medicine and Epidemiology, Evans Department of Medicine, Boston University School of Medicine, Boston, Massachusetts 02118, USA
Am J Cardiol 93:710-3. 2004..In conclusion, our data indicate little association between long-term moderate alcohol consumption and the risk of AF, but a significantly increased risk of AF among subjects consuming >36 g/day (approximatively >3 drinks/day)... - Relation of the metabolic syndrome to calcified atherosclerotic plaque in the coronary arteries and aortaR Curtis Ellison
Section of Preventive Medicine and Epidemiology, Boston University School of Medicine, Boston, Massachusetts 02118, USA
Am J Cardiol 95:1180-6. 2005..We conclude that the metabolic syndrome and most of its components are associated with a higher prevalence of calcified atherosclerotic plaque in the coronary arteries and abdominal aorta in white and African-American men and women... - Relation between serum albumin and carotid atherosclerosis: the NHLBI Family Heart StudyLuc Djousse
Evans Department of Medicine, Section of Preventive Medicine and Epidemiology, Boston University School of Medicine, Boston, Mass 02118, USA
Stroke 34:53-7. 2003..Lower concentrations of albumin have been positively related to coronary disease. The aim of this project was to assess the association between serum albumin and carotid atherosclerosis... - A genome scan for modifiers of age at onset in Huntington disease: The HD MAPS studyJian-Liang Li
Department of Neurology, Boston University School of Medicine, and Bioinformatics Program, School of Public Health, Boston University, Boston, MA, USA
Am J Hum Genet 73:682-7. 2003..Suggestive evidence for linkage was found at 4p16 (LOD=1.93), 6p21-23 (LOD=2.29), and 6q24-26 (LOD=2.28), which may be useful for investigation of genes that modify age at onset of HD... - Evidence for a modifier of onset age in Huntington disease linked to the HD gene in 4p16Luc Djousse
Evans Department of Medicine, Section of Preventive Medicine and Epidemiology, Boston University School of Medicine, Boston, Massachusetts, USA
Neurogenetics 5:109-14. 2004..Furthermore, the modifier may be present on both HD and normal chromosomes bearing the 3 allele of the MSX1 marker...
Research Grants
- Genetic Factors and Cardiovascular DiseaseLuc Djousse; Fiscal Year: 2005..Lastly, we will use data collected on participants of the GENCAC study to evaluate these genetic factors in relation to coronary calcification, a measure of coronary atherosclerosis. ..
- Fatty Acids and Heart Failure in the Physicians' Health StudyLuc Djousse; Fiscal Year: 2010....
- Fatty Acids and Heart Failure in the Physicians' Health StudyLuc Djousse; Fiscal Year: 2009....