L Djousse

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. pmc Plasma cis-vaccenic acid and risk of heart failure with antecedent coronary heart disease in male physicians
    Luc Djousse
    Division of Aging, Boston, MA, USA Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA, USA The Massachusetts Veterans Epidemiology and Research Information Center MAVERIC and Geriatric Research GRECC, Boston Veterans Affairs Healthcare System, Boston, MA, USA Electronic address
    Clin Nutr 33:478-82. 2014
  2. pmc Dietary magnesium and genetic interactions in diabetes and related risk factors: a brief overview of current knowledge
    Adela Hruby
    Department of Nutrition, Harvard School of Public Health, 677 Huntington Avenue, Building 2, Boston, MA 02115, USA
    Nutrients 5:4990-5011. 2013
  3. pmc Association between adiponectin and heart failure risk in the physicians' health study
    Luc Djousse
    Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts, USA
    Obesity (Silver Spring) 21:831-4. 2013
  4. pmc Fatty acid-binding protein 4 and incident heart failure: the Cardiovascular Health Study
    Luc Djousse
    Division of Aging, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, and Boston Veterans Affairs Healthcare System, Boston, MA 02120, USA
    Eur J Heart Fail 15:394-9. 2013
  5. pmc Association between modifiable lifestyle factors and residual lifetime risk of diabetes
    L Djousse
    Divisions of Aging, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02120, USA
    Nutr Metab Cardiovasc Dis 23:17-22. 2013
  6. pmc Plasma phospholipid concentration of cis-palmitoleic acid and risk of heart failure
    Luc Djousse
    Division of Aging, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02120, USA
    Circ Heart Fail 5:703-9. 2012
  7. pmc Fish consumption, omega-3 fatty acids and risk of heart failure: a meta-analysis
    Luc Djousse
    Division of Aging, Department of Medicine, Brigham and Women s Hospital, Boston, MA 02120, USA
    Clin Nutr 31:846-53. 2012
  8. pmc Adiposity and incident heart failure in older adults: the cardiovascular health study
    Luc Djousse
    Division of Aging, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts, USA
    Obesity (Silver Spring) 20:1936-41. 2012
  9. pmc Red blood cell membrane concentration of cis-palmitoleic and cis-vaccenic acids and risk of coronary heart disease
    Luc Djousse
    Division of Aging, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts, USA
    Am J Cardiol 110:539-44. 2012
  10. pmc Plasma fatty acid-binding protein 4, nonesterified fatty acids, and incident diabetes in older adults
    Luc Djousse
    Division of Aging, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts, USA
    Diabetes Care 35:1701-7. 2012

Detail Information

Publications89

  1. pmc Plasma cis-vaccenic acid and risk of heart failure with antecedent coronary heart disease in male physicians
    Luc Djousse
    Division of Aging, Boston, MA, USA Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA, USA The Massachusetts Veterans Epidemiology and Research Information Center MAVERIC and Geriatric Research GRECC, Boston Veterans Affairs Healthcare System, Boston, MA, USA Electronic address
    Clin Nutr 33:478-82. 2014
    ..We sought to examine the relation of plasma cis-vaccenic acid with HF with antecedent CHD...
  2. pmc Dietary magnesium and genetic interactions in diabetes and related risk factors: a brief overview of current knowledge
    Adela Hruby
    Department of Nutrition, Harvard School of Public Health, 677 Huntington Avenue, Building 2, Boston, MA 02115, USA
    Nutrients 5:4990-5011. 2013
    ..This brief review summarizes the recent evidence on dietary magnesium's role in diabetes and related traits in the presence of underlying genetic risk, and discusses future potential research directions. ..
  3. pmc Association between adiponectin and heart failure risk in the physicians' health study
    Luc Djousse
    Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts, USA
    Obesity (Silver Spring) 21:831-4. 2013
    ..To assess the association between adiponectin and incident heart failure (HF)...
  4. pmc Fatty acid-binding protein 4 and incident heart failure: the Cardiovascular Health Study
    Luc Djousse
    Division of Aging, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, and Boston Veterans Affairs Healthcare System, Boston, MA 02120, USA
    Eur J Heart Fail 15:394-9. 2013
    ..To examine the association of plasma fatty acid-binding protein 4 (FABP4) with incident heart failure...
  5. pmc Association between modifiable lifestyle factors and residual lifetime risk of diabetes
    L Djousse
    Divisions of Aging, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02120, USA
    Nutr Metab Cardiovasc Dis 23:17-22. 2013
    ..We sought to examine the association between modifiable lifestyle factors and residual lifetime risk of diabetes...
  6. pmc Plasma phospholipid concentration of cis-palmitoleic acid and risk of heart failure
    Luc Djousse
    Division of Aging, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02120, USA
    Circ Heart Fail 5:703-9. 2012
    ..We assessed whether plasma phospholipid cis-palmitoleic acid was associated with heart failure risk...
  7. pmc Fish consumption, omega-3 fatty acids and risk of heart failure: a meta-analysis
    Luc Djousse
    Division of Aging, Department of Medicine, Brigham and Women s Hospital, Boston, MA 02120, USA
    Clin Nutr 31:846-53. 2012
    ..We systematically reviewed the evidence on the association of omega-3 fatty acids and fish intake with the incidence of heart failure in this meta-analysis...
  8. pmc Adiposity and incident heart failure in older adults: the cardiovascular health study
    Luc Djousse
    Division of Aging, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts, USA
    Obesity (Silver Spring) 20:1936-41. 2012
    ..09 (95% CI: 0.99-1.21)). In conclusion, a higher WC is associated with an increased risk of HF independent of BMI in community-living older men and women...
  9. pmc Red blood cell membrane concentration of cis-palmitoleic and cis-vaccenic acids and risk of coronary heart disease
    Luc Djousse
    Division of Aging, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts, USA
    Am J Cardiol 110:539-44. 2012
    ..69 to 0.91, per SD increase). In conclusion, our data showed a positive association between RBC membrane cis-palmitoleic acid and CHD risk in male physicians. Furthermore, RBC membrane cis-vaccenic acid was inversely related to CHD...
  10. pmc Plasma fatty acid-binding protein 4, nonesterified fatty acids, and incident diabetes in older adults
    Luc Djousse
    Division of Aging, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts, USA
    Diabetes Care 35:1701-7. 2012
    ..To examine the relation of fatty acid-binding protein (FABP)4 and nonesterified fatty acids (NEFAs) to diabetes in older adults...
  11. pmc Nonesterified fatty acids and risk of sudden cardiac death in older adults
    Luc Djousse
    Division of Aging, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School and Boston Veterans Affairs Healthcare System, Boston, MA 02120, USA
    Circ Arrhythm Electrophysiol 5:273-8. 2012
    ..Although nonesterified fatty acids (NEFA) have been positively associated with coronary heart disease risk factors, limited and inconsistent data are available on the relation between NEFA and sudden cardiac death...
  12. pmc Do inflammation and procoagulation biomarkers contribute to the metabolic syndrome cluster?
    Aldi T Kraja
    Division of Statistical Genomics, Washington University School of Medicine, Saint Louis, MO, USA
    Nutr Metab (Lond) 4:28. 2007
    ..However, the relationship of inflammatory biomarkers to MetS is not clear...
  13. pmc Alcohol consumption, physical activity, and chronic disease risk factors: a population-based cross-sectional survey
    Kenneth J Mukamal
    Division of General Medicine and Primary Care, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts, USA
    BMC Public Health 6:118. 2006
    ..Whether the association of alcohol consumption and cardiovascular disease is the product of confounding and the degree to which this concern applies to other behaviors are unclear...
  14. pmc Genetic analysis of the GRIK2 modifier effect in Huntington's disease
    Wenqi Zeng
    Molecular Neurogenetics Unit, Center for Human Genetic Research, Massachusetts General Hospital, 185 Cambridge Street, Boston, MA 02114, USA
    BMC Neurosci 7:62. 2006
    ....
  15. pmc Secular trends of heart failure among US male physicians
    Luc Djousse
    Division of Aging, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02120, USA
    Am Heart J 154:855-60. 2007
    ..Heart failure (HF) remains a major public health issue. Data on long-term trends in the incidence of HF and survival after its onset are limited...
  16. pmc Chocolate consumption is inversely associated with prevalent coronary heart disease: the National Heart, Lung, and Blood Institute Family Heart Study
    Luc Djousse
    Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston 02120, MA, USA
    Clin Nutr 30:182-7. 2011
    ..However, limited data are available on the association of chocolate consumption and the risk of coronary heart disease (CHD). We sought to examine the association between chocolate consumption and prevalent CHD...
  17. pmc Dietary omega-3 fatty acids and fish consumption and risk of type 2 diabetes
    Luc Djousse
    Division of Aging and Preventive Medicine, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA, USA
    Am J Clin Nutr 93:143-50. 2011
    ..Although dietary omega-3 (n-3) fatty acids may confer some cardiovascular benefits, it is unclear whether these nutrients may also unfavorably affect risk of type 2 diabetes (T2D)...
  18. pmc Egg consumption and risk of heart failure in the Physicians' Health Study
    Luc Djousse
    Division of Aging, Brigham and Women s Hospital and Harvard Medical School, 1620 Tremont St, Third Floor, Boston MA 02120, USA
    Circulation 117:512-6. 2008
    ..Although eggs are important sources of dietary cholesterol and other nutrients, little is known about the association between egg consumption and heart failure (HF) risk...
  19. pmc Cystatin C and risk of heart failure in the Physicians' Health Study (PHS)
    Luc Djousse
    Department of Medicine, Division of Aging, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02120, USA
    Am Heart J 155:82-6. 2008
    ..Chronic kidney disease is a risk factor for heart failure (HF). Although cystatin C can detect early kidney dysfunction, limited data are available on the association between cystatin C and HF...
  20. doi request reprint Relation of albuminuria to left ventricular mass (from the HyperGEN Study)
    Luc Djousse
    Division of Aging, Department of Medicine, Brigham and Women s Hospital, Boston, Massachusetts, USA
    Am J Cardiol 101:212-6. 2008
    ..In conclusion, these results suggest that albuminuria is positively associated with LV mass in normotensive subjects as it is in hypertensive subjects...
  21. ncbi request reprint Diet and metabolic syndrome
    L Djousse
    Division of Aging, Department of Medicine, Brigham and Women s Hospital, Boston, MA 02120, USA
    Endocr Metab Immune Disord Drug Targets 10:124-37. 2010
    ..This manuscript reviews current evidence on dietary patterns, consumption of fat, whole grains, carbohydrate quality and quantity, and moderate alcohol consumption as they relate to metabolic syndrome...
  22. pmc Egg consumption in relation to cardiovascular disease and mortality: the Physicians' Health Study
    Luc Djousse
    Division of Aging, Brigham and Women s Hospital and Harvard Medical School, 1620 Tremont Street, 3rd Floor, Boston MA 02120, USA
    Am J Clin Nutr 87:964-9. 2008
    ..Although eggs are important sources of cholesterol and other nutrients, limited and inconsistent data are available on the effects of egg consumption on the risk of CVD and mortality...
  23. pmc Nut consumption and risk of stroke in US male physicians
    Luc Djousse
    Division of Aging, Department of Medicine, Brigham and Women s Hospital, Boston, MA 02120, USA
    Clin Nutr 29:605-9. 2010
    ..We sought to examine whether nut consumption is associated with total and subtypes of stroke...
  24. pmc Alcohol consumption and risk of cardiovascular disease and death in women: potential mediating mechanisms
    Luc Djousse
    Division of Aging, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02120, USA
    Circulation 120:237-44. 2009
    ..We examined the association between alcohol and CVD and death in 26 399 women and estimated the proportion of reduced risk of CVD/death explained by a series of intermediate factors...
  25. pmc Parental history of myocardial infarction and risk of heart failure in male physicians
    L Djousse
    Division of Aging, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02120, USA
    Eur J Clin Invest 38:896-901. 2008
    ..Although heart failure (HF) remains a major public health issue, limited data are available on the utility of parental information on the risk of HF in offspring...
  26. pmc Relation between modifiable lifestyle factors and lifetime risk of heart failure
    Luc Djousse
    Division of Aging, Brigham and Women s Hospital and Harvard Medical School, 1620 Tremont St, Third Floor, Boston, MA 02120, USA
    JAMA 302:394-400. 2009
    ..The lifetime risk of heart failure at age 40 years is approximately 1 in 5 in the general population; however, little is known about the association between modifiable lifestyle factors and the remaining lifetime risk of heart failure...
  27. pmc Apolipoprotein e, alcohol consumption, and risk of ischemic stroke: the Framingham Heart Study revisited
    Luc Djousse
    Division of Aging, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts 02120, USA
    J Stroke Cerebrovasc Dis 18:384-8. 2009
    ..We sought to examine whether epsilon(4) allele of the apoE gene influences the association between alcohol consumption and ischemic stroke or high-density lipoprotein (HDL) cholesterol...
  28. pmc Egg consumption and risk of type 2 diabetes in men and women
    Luc Djousse
    Division of Aging, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
    Diabetes Care 32:295-300. 2009
    ..This project sought to examine the relation between egg intake and the risk of type 2 diabetes in two large prospective cohorts...
  29. pmc Nut consumption and risk of heart failure in the Physicians' Health Study I
    Luc Djousse
    Division of Aging and Preventive Medicine, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02120, USA
    Am J Clin Nutr 88:930-3. 2008
    ....
  30. pmc Nut consumption and risk of hypertension in US male physicians
    Luc Djousse
    Division of Aging, Department of Medicine, Brigham and Women s Hospital, Boston, MA 02120, USA
    Clin Nutr 28:10-4. 2009
    ..Hypertension is a risk factor for cardiovascular disease and dietary factors may play an important role in its prevention. We sought to examine the association between nut consumption and incident hypertension...
  31. ncbi request reprint Dietary cholesterol and coronary artery disease: a systematic review
    Luc Djousse
    Division of Aging, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, 3rd Floor, Boston, MA 02120, USA
    Curr Atheroscler Rep 11:418-22. 2009
    ..This article reviews the current evidence on the association between dietary cholesterol and the risk of CHD...
  32. pmc Alcohol consumption and heart failure in hypertensive US male physicians
    Luc Djousse
    Division of Aging, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts, USA
    Am J Cardiol 102:593-7. 2008
    ..In conclusion, our data suggested that light to moderate alcohol consumption was associated with a lower risk of HF in hypertensive male physicians...
  33. pmc Alcohol consumption and heart failure: a systematic review
    Luc Djousse
    Division of Aging, Brigham and Women s Hospital, Harvard Medical School, 1620 Tremont Street, 3rd Floor, Boston, MA 02120, USA
    Curr Atheroscler Rep 10:117-20. 2008
    ..This article reviews current evidence on the association between alcohol consumption and HF...
  34. ncbi request reprint Breakfast cereals and risk of heart failure in the physicians' health study I
    Luc Djousse
    Division of Aging, Brigham and Women s Hospital and Harvard Medical School, 1620 Tremont St, Third Floor, Boston, MA 02120, USA
    Arch Intern Med 167:2080-5. 2007
    ..Consumption of grain products and dietary fiber has been shown to reduce the risk of hypertension and myocardial infarction. However, it is not known whether a higher consumption of breakfast cereals is associated with risk of HF...
  35. ncbi request reprint Alcohol consumption and type 2 diabetes among older adults: the Cardiovascular Health Study
    Luc Djousse
    Division of Aging, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, 1620 Tremont St, 3rd Floor, Boston, MA 02120, USA
    Obesity (Silver Spring) 15:1758-65. 2007
    ..The objective was to examine the role of total and beverage-specific alcohol consumption on the incidence of type 2 diabetes mellitus (DM) among elderly men and women...
  36. ncbi request reprint Alcohol consumption and plasma atrial natriuretic peptide (from the HyperGEN study)
    Luc Djousse
    Division of Aging, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts, USA
    Am J Cardiol 98:628-32. 2006
    ..0001 each for trend). In conclusion, our data have shown a positive and linear association between alcohol consumption and ANP in men and women, irrespective of race...
  37. pmc Fucosyltransferase 3 polymorphism and atherothrombotic disease in the Framingham Offspring Study
    Luc Djousse
    Division of Aging, Brigham and Women s Hospital and Harvard Medical School, Boston, MA, USA
    Am Heart J 153:636-9. 2007
    ..Previous studies have suggested a positive association between phenotypes of fucosyltransferase 3 (FUT3) gene (also known as Lewis gene) and coronary heart disease...
  38. ncbi request reprint Alcohol consumption and risk of heart failure in the Physicians' Health Study I
    Luc Djousse
    Division of Aging, Brigham and Women s Hospital and Harvard Medical School, 1620 Tremont St, 3rd Floor, Boston MA 02120, USA
    Circulation 115:34-9. 2007
    ..Data on the effects of moderate alcohol consumption on the risk of HF have been sparse and inconsistent. This study sought to evaluate the association between moderate alcohol consumption and incident HF...
  39. ncbi request reprint Dietary linolenic acid and fasting glucose and insulin: the National Heart, Lung, and Blood Institute Family Heart Study
    Luc Djousse
    Division of Aging, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02120, USA
    Obesity (Silver Spring) 14:295-300. 2006
    ..To assess whether dietary linolenic acid is associated with fasting insulin and glucose...
  40. pmc Egg consumption and risk of type 2 diabetes in older adults
    Luc Djousse
    Division of Aging, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02120, USA
    Am J Clin Nutr 92:422-7. 2010
    ..Type 2 diabetes (T2D) remains an important public health issue in the United States. There are limited and inconsistent data on the association between egg consumption and fasting glucose or incident diabetes...
  41. ncbi request reprint Influence of saturated fat and linolenic acid on the association between intake of dairy products and blood pressure
    Luc Djousse
    Division of Aging, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02120, USA
    Hypertension 48:335-41. 2006
    ..This suggests that consumption of low-fat dairy products might be more beneficial for preventing HTN...
  42. pmc Plasma omega-3 fatty acids and incident diabetes in older adults
    Luc Djousse
    Division of Aging, Department of Epidemiology, University of Washington, Seattle, WA, USA
    Am J Clin Nutr 94:527-33. 2011
    ....
  43. ncbi request reprint Influence of alcohol dehydrogenase 1C polymorphism on the alcohol-cardiovascular disease association (from the Framingham Offspring Study)
    Luc Djousse
    Section of Preventive Medicine and Epidemiology, Evans Department of Medicine, Boston University, Boston, MA, USA
    Am J Cardiol 96:227-32. 2005
    ..The interaction does not appear to be mediated through effects on high-density lipoprotein cholesterol...
  44. pmc Nut consumption and risk of atrial fibrillation in the Physicians' Health Study
    O Khawaja
    Harvard Medical School, Boston, MA, USA
    Nutr J 11:17. 2012
    ..3 million people in USA and 4.5 million people in European Union. The aim of the study was to examine the association between nut consumption and incident atrial fibrillation...
  45. pmc Relation of alcohol consumption and coronary heart disease in hypertensive male physicians (from the Physicians' Health Study)
    Kathryn A Britton
    Harvard Medical School, Massachusetts Veterans Epidemiology and Research Information Center MAVERIC, Boston Veterans Affairs Healthcare System, Boston, MA, USA
    Am J Cardiol 104:932-5. 2009
    ..In conclusion, our data demonstrated an inverse relation between moderate alcohol consumption and CHD in hypertensive men...
  46. pmc Lipoprotein receptor-related protein 1 variants and dietary fatty acids: meta-analysis of European origin and African American studies
    C E Smith
    Nutrition and Genomics Laboratory, Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, MA, USA
    Int J Obes (Lond) 37:1211-20. 2013
    ..The study objectives were to evaluate (i) relationships between LRP1 genotype and anthropometric traits, and (ii) whether these relationships were modified by dietary fatty acids...
  47. ncbi request reprint Alcohol consumption and metabolic syndrome: does the type of beverage matter?
    Luc Djousse
    Boston University School of Medicine, Room B 612, 715 Albany Street, Boston, Massachusetts 02118, USA
    Obes Res 12:1375-85. 2004
    ..To examine the association between total and beverage-specific alcohol consumption and the prevalence odds of metabolic syndrome (MS)...
  48. ncbi request reprint Influence of apolipoprotein E, smoking, and alcohol intake on carotid atherosclerosis: National Heart, Lung, and Blood Institute Family Heart Study
    Luc Djousse
    Section of Preventive Medicine and Epidemiology, Evans Department of Medicine, Boston University School of Medicine, Boston, Mass 02118, USA
    Stroke 33:1357-61. 2002
    ..Apolipoprotein E (apoE) isoforms and lifestyle factors play an important role in the development of coronary heart disease. The association of apoE and carotid atherosclerosis remains controversial...
  49. ncbi request reprint Weight loss in early stage of Huntington's disease
    L Djousse
    Evans Department of Medicine, Section of Preventive Medicine and Epidemiology, Boston University School of Medicine, Boston, MA 02118, USA
    Neurology 59:1325-30. 2002
    ..In transgenic mouse models of HD, weight loss is recognized as a feature associated with the disease onset. It is unclear whether a similar pattern occurs in humans...
  50. ncbi request reprint Lack of association between the angiotensin-converting enzyme insertion/deletion polymorphism and plasminogen activator inhibitor-1 antigen levels in the National Heart, Lung, and Blood Institute Family Heart Study
    J S Pankow
    Department of Epidemiology, School of Public Health, University of North Carolina at Chapel Hill, 27514, USA
    Blood Coagul Fibrinolysis 11:551-8. 2000
    ..Our findings suggest that the ACE insertion/deletion polymorphism has relatively little, if any, influence on circulating PAI-1 levels in the population at large...
  51. pmc Nut consumption and risk of type II diabetes in the Physicians' Health Study
    J Kochar
    Department of Medicine, Medical College of Wisconsin, Milwaukee, WI, USA
    Eur J Clin Nutr 64:75-9. 2010
    ..We sought to examine the association between nut consumption and the risk of DM...
  52. ncbi request reprint Glycemic index, glycemic load, and cereal fiber intake and risk of type 2 diabetes in US black women
    Supriya Krishnan
    Slone Epidemiology Center, Boston, MA 02215, USA
    Arch Intern Med 167:2304-9. 2007
    ..Previous studies of carbohydrate quality and risk of type 2 diabetes mellitus have yielded inconsistent findings. Because diet is in part culturally determined, a study of dietary factors in US black women is of interest...
  53. ncbi request reprint Serum albumin and risk of myocardial infarction and all-cause mortality in the Framingham Offspring Study
    Luc Djousse
    Department of Medicine, Boston University School of Medicine, Boston, Mass 02118, USA
    Circulation 106:2919-24. 2002
    ....
  54. ncbi request reprint Evidence for major genes influencing pulmonary function in the NHLBI family heart study
    J B Wilk
    Section of Preventive Medicine and Epidemiology, Boston University School of Medicine, Boston, Massachusetts 02118, USA
    Genet Epidemiol 19:81-94. 2000
    ..These results support the hypothesis that complex relationships exist for lung function traits and that multiple genes and environmental factors influence lung function...
  55. ncbi request reprint Dietary linolenic acid is inversely associated with plasma triacylglycerol: the National Heart, Lung, and Blood Institute Family Heart Study
    Luc Djousse
    Section of Preventive Medicine and Epidemiology, Evans Department of Medicine, Boston University School of Medicine, Room B 612, 715 Albany Street, Boston, MA 02118, USA
    Am J Clin Nutr 78:1098-102. 2003
    ..Dietary intake of linolenic acid is associated with a decreased risk of cardiovascular disease mortality. However, the mechanisms by which dietary linolenic acid affects cardiovascular disease risk are not clearly understood...
  56. ncbi request reprint Alcohol consumption and risk of lung cancer: the Framingham Study
    Luc Djousse
    Section of Preventive Medicine and Epidemiology, Evans Department of Medicine, Boston University School of Medicine, Boston, MA 02118, USA
    J Natl Cancer Inst 94:1877-82. 2002
    ..Reports on the association between alcohol consumption and the risk of lung cancer have been inconsistent. The purpose of this study was to assess this association in a cohort study...
  57. doi request reprint Fish consumption and risk of stroke and its subtypes: accumulative evidence from a meta-analysis of prospective cohort studies
    P Xun
    Department of Nutrition, Gillings Schools of Global Public Health and School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599 7461, USA
    Eur J Clin Nutr 66:1199-207. 2012
    ..To provide a reliable assessment of the hypothesized association of fish consumption with stroke risk accumulatively, an updated meta-analysis of published prospective cohort studies was conducted...
  58. pmc Red meat consumption and risk of heart failure in male physicians
    A Ashaye
    Boston University School of Public Health, Boston, MA, USA
    Nutr Metab Cardiovasc Dis 21:941-6. 2011
    ..However, it is not known whether red meat intake influences the risk of HF. We therefore examined the association between red meat consumption and incident HF...
  59. ncbi request reprint Alcohol consumption and risk of intermittent claudication in the Framingham Heart Study
    L Djousse
    Department of Medicine, Section of Preventive Medicine and Epidemiology Boston University School of Medicine, Boston, Massachusetts, USA
    Circulation 102:3092-7. 2000
    ..The purpose of this study was to assess the relation of alcohol consumption and type of beverage to the development of IC among participants in the Framingham Heart Study...
  60. ncbi request reprint Relation between dietary linolenic acid and coronary artery disease in the National Heart, Lung, and Blood Institute Family Heart Study
    L Djousse
    Section of Preventive Medicine and Epidemiology, Evans Department of Medicine, The School of Medicine, Boston University, Boston, MA 02118, USA
    Am J Clin Nutr 74:612-9. 2001
    ..Studies in humans and animals also reported an inverse association between alpha-linolenic acid and cardiovascular disease morbidity and mortality...
  61. doi request reprint Effects of cocoa products/dark chocolate on serum lipids: a meta-analysis
    O A Tokede
    Division of Aging, Department of Medicine, Brigham and Women s Hospital, Boston, MA 02120 1613, USA
    Eur J Clin Nutr 65:879-86. 2011
    ..06 mg/dl (-13.45 to 3.32 mg/dl)). These data are consistent with beneficial effects of dark chocolate/cocoa products on total and LDL cholesterol and no major effects on HDL and TG in short-term intervention trials...
  62. ncbi request reprint Effect of serum albumin and bilirubin on the risk of myocardial infarction (the Framingham Offspring Study)
    Luc Djousse
    The Department of Medicine, Section of Preventive Medicine and Epidemiology, Boston University School of Medicine, Boston, Massachusetts 02118, USA
    Am J Cardiol 91:485-8. 2003
  63. pmc Physical activity and weight gain prevention
    I Min Lee
    Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02215, USA
    JAMA 303:1173-9. 2010
    ..In 2008, federal guidelines recommended at least 150 minutes per week (7.5 metabolic equivalent [MET] hours per week) of moderate-intensity activity for "substantial health benefits."..
  64. pmc Normal systolic blood pressure and risk of heart failure in US male physicians
    Kathryn A Britton
    Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
    Eur J Heart Fail 11:1129-34. 2009
    ..However, limited data are available on the relationship between normotensive SBP and the risk of HF...
  65. pmc Change in high-density lipoprotein cholesterol and incident coronary heart disease in apparently healthy male physicians
    Catherine Rahilly-Tierney
    Massachusetts Veterans Epidemiology and Research Information Center, Office of Research and Development, Department of Veterans Affairs, Boston, Massachusetts, USA
    Am J Cardiol 102:1663-7. 2008
    ..43 (95% CI 0.23 to 0.83) for subjects with an HDL cholesterol increase >or=12.5 mg/dl. In conclusion, our findings were consistent with an inverse graded relation between 14-year increase in HDL cholesterol and risk of subsequent CHD...
  66. pmc Lifestyle risk factors and new-onset diabetes mellitus in older adults: the cardiovascular health study
    Dariush Mozaffarian
    Divisions of Cardiovascular Medicine, Department of Medicine, Brigham and Women s Hospital, Harvard School of Public Health, 665 Huntington Ave, Bldg 2 319, Boston, MA 02115, USA
    Arch Intern Med 169:798-807. 2009
    ..The objective of this study was to determine how lifestyle factors, assessed in combination, relate to new-onset diabetes in a broad and relatively unselected population of older adults...
  67. ncbi request reprint Alcohol consumption and the risk of bladder cancer in the Framingham Heart Study
    Luc Djousse
    Preventive Medicine and Epidemiology Section, Evans Department of Medicine, Boston University School of Medicine, Rm B 612, 715 Albany St, Boston, MA 02118, USA
    J Natl Cancer Inst 96:1397-400. 2004
    ..03), whereas wine (P(trend) =.7) and spirit (P(trend) =.2) consumption were not. Our data suggest that total and beverage-specific alcohol consumption are not associated with an increased risk of bladder cancer...
  68. ncbi request reprint Intake of fruits, vegetables, and dairy products in early childhood and subsequent blood pressure change
    Lynn L Moore
    Section of Preventive Medicine and Epidemiology, Boston University School of Medicine, Boston, Massachusetts 02118, USA
    Epidemiology 16:4-11. 2005
    ..Diets characterized by high intakes of fruits and vegetables and low-fat dairy products (for example, the DASH diet) have been shown to reduce blood pressure in adults. The effects of similar diets on children's blood pressure are unknown...
  69. pmc Transferability and fine-mapping of glucose and insulin quantitative trait loci across populations: CARe, the Candidate Gene Association Resource
    C T Liu
    Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA
    Diabetologia 55:2970-84. 2012
    ..We tested the transferability of 18 single-nucleotide polymorphisms (SNPs) associated with glycaemic traits identified in European ancestry (EuA) populations in 5,984 non-diabetic AfAs...
  70. ncbi request reprint Acute effects of a high-fat meal with and without red wine on endothelial function in healthy subjects
    L Djousse
    Section of Preventive Medicine and Epidemiology, Evans Memorial Department of Medicine, Boston University School of Medicine, Massachusetts, USA
    Am J Cardiol 84:660-4. 1999
    ..Under these conditions, we did not demonstrate a beneficial acute effect of red wine on endothelial function...
  71. doi request reprint Exceptional longevity in men: modifiable factors associated with survival and function to age 90 years
    Laurel B Yates
    Division of Aging, Brigham and Women s Hospital, 1620 Tremont St, Boston, MA 02120, USA
    Arch Intern Med 168:284-90. 2008
    ..We examined modifiable factors associated with a life span of 90 or more years and late-life function in men...
  72. ncbi request reprint Breakfast cereals and risk of type 2 diabetes in the Physicians' Health Study I
    Jinesh Kochar
    Division of Aging, Brigham and Women s Hospital and Harvard Medical School, 1620 Tremont Street, 3rd Floor, Boston MA 02120, USA
    Obesity (Silver Spring) 15:3039-44. 2007
    ..To examine the association between breakfast cereal consumption and the risk of type 2 diabetes (DM)...
  73. pmc Incidence of cardiovascular disease and cancer in advanced age: prospective cohort study
    Jane A Driver
    Division of Aging, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02215, USA
    BMJ 337:a2467. 2008
    ..To investigate the influence of increasing age on the incidence and remaining lifetime risk of cardiovascular disease and cancer in a cohort of older men...
  74. ncbi request reprint Dietary linolenic acid and adjusted QT and JT intervals in the National Heart, Lung, and Blood Institute Family Heart study
    Luc Djousse
    Section of Preventive Medicine and Epidemiology, Evans Department of Medicine, Boston University School of Medicine, Boston, Massachusetts 02118, USA
    J Am Coll Cardiol 45:1716-22. 2005
    ..The goal of this study was to examine whether higher consumption of total linolenic acid was associated with rate-adjusted QT and JT intervals (QTrr and JTrr, respectively)...
  75. ncbi request reprint Interaction of normal and expanded CAG repeat sizes influences age at onset of Huntington disease
    L Djousse
    Section of Preventive Medicine and Epidemiology, Boston University School of Medicine, Boston, Massachusetts 02118, USA
    Am J Med Genet A 119:279-82. 2003
    ..These findings suggest that an increase in the size of the normal repeat may mitigate the expression of the disease among HD affected persons with large expanded CAG repeats...
  76. ncbi request reprint A genome-wide scan of pulmonary function measures in the National Heart, Lung, and Blood Institute Family Heart Study
    Jemma B Wilk
    Boston University School of Medicine, B 601, 715 Albany Street, Boston, MA 02118, USA
    Am J Respir Crit Care Med 167:1528-33. 2003
    ..0. FEV1 and FVC were suggestively linked to regions on chromosome 18 with multipoint LOD scores of 2.4 for FEV1 and 1.5 for FVC at 31 cM (D18S843) and a LOD of 2.9 for FVC at 79 cM (D18S858)...
  77. ncbi request reprint Is alcohol consumption associated with calcified atherosclerotic plaque in the coronary arteries and aorta?
    R Curtis Ellison
    Section of Preventive Medicine and Epidemiology, Boston University School of Medicine, Boston, MA 02118, USA
    Am Heart J 152:177-82. 2006
    ..Previous results have been conflicting, showing increases, decreases, or no effect of alcohol on risk of calcified plaque...
  78. ncbi request reprint Overall and central obesity and risk of type 2 diabetes in U.S. black women
    Supriya Krishnan
    Slone Epidemiology Center, 1010, Commonwealth Avenue, Fourth Floor, Boston, MA 02215, USA
    Obesity (Silver Spring) 15:1860-6. 2007
    ..We examined the association of BMI, abdominal obesity, and weight gain with risk of type 2 diabetes...
  79. ncbi request reprint Dietary linolenic acid is inversely associated with calcified atherosclerotic plaque in the coronary arteries: the National Heart, Lung, and Blood Institute Family Heart Study
    Luc Djousse
    Evans Department of Medicine, Section of Preventive Medicine and Epidemiology, Boston University School of Medicine, Boston, Mass 02118, USA
    Circulation 111:2921-6. 2005
    ..High dietary intake of linolenic acid is associated with a lower risk of cardiovascular disease mortality. However, little is known about the association between linolenic acid and subclinical atherosclerosis...
  80. ncbi request reprint Fruit and vegetable consumption and LDL cholesterol: the National Heart, Lung, and Blood Institute Family Heart Study
    Luc Djousse
    Section of Preventive Medicine and Epidemiology, Evans Department of Medicine, Boston University School of Medicine, Boston, MA 02118, USA
    Am J Clin Nutr 79:213-7. 2004
    ..An elevated LDL-cholesterol concentration is associated with an increased risk of cardiovascular disease. The association between fruit and vegetable consumption and LDL has been inconsistent...
  81. pmc Prediction and classification of cardiovascular disease risk in older adults with diabetes
    K J Mukamal
    Division of General Medicine and Primary Care, Beth Israel Deaconess Medical Center, 1309 Beacon Street, Brookline, MA 02446, USA
    Diabetologia 56:275-83. 2013
    ..We sought to derive and validate a cardiovascular disease (CVD) prediction algorithm for older adults with diabetes, and evaluate the incremental benefit of adding novel circulating biomarkers and measures of subclinical atherosclerosis...
  82. ncbi request reprint Genome-wide linkage analyses for age at diagnosis of hypertension and early-onset hypertension in the HyperGEN study
    Jemma B Wilk
    Boston University School of Medicine, Boston, Massachusetts 02118, USA
    Am J Hypertens 17:839-44. 2004
    ....
  83. pmc Genome-wide significance for a modifier of age at neurological onset in Huntington's disease at 6q23-24: the HD MAPS study
    Jian Liang Li
    Department of Neurology, Boston University School of Medicine, Boston, MA, USA
    BMC Med Genet 7:71. 2006
    ....
  84. ncbi request reprint Long-term alcohol consumption and the risk of atrial fibrillation in the Framingham Study
    Luc Djousse
    Section of Preventive Medicine and Epidemiology, Evans Department of Medicine, Boston University School of Medicine, Boston, Massachusetts 02118, USA
    Am J Cardiol 93:710-3. 2004
    ..In conclusion, our data indicate little association between long-term moderate alcohol consumption and the risk of AF, but a significantly increased risk of AF among subjects consuming >36 g/day (approximatively >3 drinks/day)...
  85. pmc Evidence for a modifier of onset age in Huntington disease linked to the HD gene in 4p16
    Luc Djousse
    Evans Department of Medicine, Section of Preventive Medicine and Epidemiology, Boston University School of Medicine, Boston, Massachusetts, USA
    Neurogenetics 5:109-14. 2004
    ..Furthermore, the modifier may be present on both HD and normal chromosomes bearing the 3 allele of the MSX1 marker...
  86. pmc A genome scan for modifiers of age at onset in Huntington disease: The HD MAPS study
    Jian Liang Li
    Department of Neurology, Boston University School of Medicine, and Bioinformatics Program, School of Public Health, Boston University, Boston, MA, USA
    Am J Hum Genet 73:682-7. 2003
    ..Suggestive evidence for linkage was found at 4p16 (LOD=1.93), 6p21-23 (LOD=2.29), and 6q24-26 (LOD=2.28), which may be useful for investigation of genes that modify age at onset of HD...
  87. ncbi request reprint Relation of the metabolic syndrome to calcified atherosclerotic plaque in the coronary arteries and aorta
    R Curtis Ellison
    Section of Preventive Medicine and Epidemiology, Boston University School of Medicine, Boston, Massachusetts 02118, USA
    Am J Cardiol 95:1180-6. 2005
    ..We conclude that the metabolic syndrome and most of its components are associated with a higher prevalence of calcified atherosclerotic plaque in the coronary arteries and abdominal aorta in white and African-American men and women...
  88. ncbi request reprint Relation between serum albumin and carotid atherosclerosis: the NHLBI Family Heart Study
    Luc Djousse
    Evans Department of Medicine, Section of Preventive Medicine and Epidemiology, Boston University School of Medicine, Boston, Mass 02118, USA
    Stroke 34:53-7. 2003
    ..Lower concentrations of albumin have been positively related to coronary disease. The aim of this project was to assess the association between serum albumin and carotid atherosclerosis...

Research Grants4

  1. Genetic Factors and Cardiovascular Disease
    Luc Djousse; Fiscal Year: 2005
    ..Lastly, we will use data collected on participants of the GENCAC study to evaluate these genetic factors in relation to coronary calcification, a measure of coronary atherosclerosis. ..
  2. Fatty Acids and Heart Failure in the Physicians' Health Study
    Luc Djousse; Fiscal Year: 2009
    ....
  3. Fatty Acids and Heart Failure in the Physicians' Health Study
    Luc Djousse; Fiscal Year: 2010
    ....
  4. Fatty Acids and Heart Failure in the Physicians' Health Study
    Luc Djousse; Fiscal Year: 2009
    ....