Fabio Demontis

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. pmc Integration of Insulin receptor/Foxo signaling and dMyc activity during muscle growth regulates body size in Drosophila
    Fabio Demontis
    Department of Genetics, Howard Hughes Medical Institute, Harvard Medical School, 77 Avenue Louis Pasteur, Boston, MA 02115, USA
    Development 136:983-93. 2009
  2. pmc FOXO/4E-BP signaling in Drosophila muscles regulates organism-wide proteostasis during aging
    Fabio Demontis
    Department of Genetics, Harvard Medical School, Boston, MA 02115, USA
    Cell 143:813-25. 2010

Collaborators

Detail Information

Publications2

  1. pmc Integration of Insulin receptor/Foxo signaling and dMyc activity during muscle growth regulates body size in Drosophila
    Fabio Demontis
    Department of Genetics, Howard Hughes Medical Institute, Harvard Medical School, 77 Avenue Louis Pasteur, Boston, MA 02115, USA
    Development 136:983-93. 2009
    ..Thus, maximal dMyc transcriptional activity depends on InR to control muscle mass, which in turn induces a systemic behavioral response to allocate body size and proportions...
  2. pmc FOXO/4E-BP signaling in Drosophila muscles regulates organism-wide proteostasis during aging
    Fabio Demontis
    Department of Genetics, Harvard Medical School, Boston, MA 02115, USA
    Cell 143:813-25. 2010
    ..These findings reveal an organism-wide regulation of proteostasis in response to muscle aging and a key role of FOXO/4E-BP signaling in the coordination of organismal and tissue aging...