Anthony V D'Amico

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. ncbi request reprint Impact of the percentage of positive prostate cores on prostate cancer-specific mortality for patients with low or favorable intermediate-risk disease
    Anthony V D'Amico
    Department of Radiation Oncology, Brigham and Women s Hospital and Dana Farber Cancer Institute, Boston, MA 02215, USA
    J Clin Oncol 22:3726-32. 2004
  2. ncbi request reprint Impact on rectal dose from the use of a prostate immobilization and rectal localization device for patients receiving dose escalated 3D conformal radiation therapy
    Mona V Sanghani
    Department of Radiation Oncology, The Brigham and Women s Hospital, Dana Farber Cancer Institute, Boston, MA, USA
    Urol Oncol 22:165-8. 2004
  3. ncbi request reprint 6-month androgen suppression plus radiation therapy vs radiation therapy alone for patients with clinically localized prostate cancer: a randomized controlled trial
    Anthony V D'Amico
    Department of Radiation Oncology, Brigham and Women s Hospital and Dana Farber Cancer Institute, Boston, Mass 02215, USA
    JAMA 292:821-7. 2004
  4. ncbi request reprint Prostate specific antigen doubling time as a surrogate end point for prostate cancer specific mortality following radical prostatectomy or radiation therapy
    Anthony V D'Amico
    Department of Radiation Oncology, Brigham and Women s Hospital and Dana Farber Cancer Institute, Boston, Massachusetts 02215, USA
    J Urol 172:S42-6; discussion S46-7. 2004
  5. ncbi request reprint Surrogate end point for prostate cancer specific mortality in patients with nonmetastatic hormone refractory prostate cancer
    Anthony V D'Amico
    Department of Radiation Oncology, Brigham and Women s Hospital and Dana Farber Cancer Institute, Boston, Massachusetts 02115, USA
    J Urol 173:1572-6. 2005
  6. ncbi request reprint Short- vs long-term androgen suppression plus external beam radiation therapy and survival in men of advanced age with node-negative high-risk adenocarcinoma of the prostate
    Anthony V D'Amico
    Department of Radiation Oncology, Brigham and Women s Hospital, Dana Farber Cancer Institute, Boston, Massachusetts, USA
    Cancer 109:2004-10. 2007
  7. ncbi request reprint Time to an undetectable prostate-specific antigen (PSA) after androgen suppression therapy for postoperative or postradiation PSA recurrence and prostate cancer-specific mortality
    Anthony V D'Amico
    Department of Radiation Oncology, Brigham and Women s Hospital and Dana Farber Cancer Institute, Boston, Massachusetts, USA
    Cancer 109:1290-5. 2007
  8. ncbi request reprint Pretreatment PSA velocity and risk of death from prostate cancer following external beam radiation therapy
    Anthony V D'Amico
    Department of Radiation Oncology, Brigham and Women s Hospital and Dana Farber Cancer Institute, Boston, Mass 02215, USA
    JAMA 294:440-7. 2005
  9. ncbi request reprint Identifying patients at risk for significant versus clinically insignificant postoperative prostate-specific antigen failure
    Anthony V D'Amico
    Brigham and Women s Hospital, Department of Radiation Oncology, Dana Faber Cancer Institute, Harvard Medical School, Boston, MA 02115, USA
    J Clin Oncol 23:4975-9. 2005
  10. ncbi request reprint Prostate-specific antigen response duration and risk of death for patients with hormone-refractory metastatic prostate cancer
    Anthony V D'Amico
    Department of Radiation Oncology, Brigham and Women s Hospital, Dana Farber Cancer Institute, Boston, Massachusetts, USA
    Urology 66:571-6. 2005

Detail Information

Publications84

  1. ncbi request reprint Impact of the percentage of positive prostate cores on prostate cancer-specific mortality for patients with low or favorable intermediate-risk disease
    Anthony V D'Amico
    Department of Radiation Oncology, Brigham and Women s Hospital and Dana Farber Cancer Institute, Boston, MA 02215, USA
    J Clin Oncol 22:3726-32. 2004
    ..We investigated whether pretreatment factors predicted time to prostate cancer-specific mortality (PCSM) after conventional-dose and conformal radiation therapy (CRT)...
  2. ncbi request reprint Impact on rectal dose from the use of a prostate immobilization and rectal localization device for patients receiving dose escalated 3D conformal radiation therapy
    Mona V Sanghani
    Department of Radiation Oncology, The Brigham and Women s Hospital, Dana Farber Cancer Institute, Boston, MA, USA
    Urol Oncol 22:165-8. 2004
    ....
  3. ncbi request reprint 6-month androgen suppression plus radiation therapy vs radiation therapy alone for patients with clinically localized prostate cancer: a randomized controlled trial
    Anthony V D'Amico
    Department of Radiation Oncology, Brigham and Women s Hospital and Dana Farber Cancer Institute, Boston, Mass 02215, USA
    JAMA 292:821-7. 2004
    ....
  4. ncbi request reprint Prostate specific antigen doubling time as a surrogate end point for prostate cancer specific mortality following radical prostatectomy or radiation therapy
    Anthony V D'Amico
    Department of Radiation Oncology, Brigham and Women s Hospital and Dana Farber Cancer Institute, Boston, Massachusetts 02215, USA
    J Urol 172:S42-6; discussion S46-7. 2004
    ..A short posttreatment prostate specific antigen (PSA)-doubling time (DT) following radical prostatectomy or radiation therapy was evaluated as a surrogate end point for prostate cancer specific mortality (PCSM)...
  5. ncbi request reprint Surrogate end point for prostate cancer specific mortality in patients with nonmetastatic hormone refractory prostate cancer
    Anthony V D'Amico
    Department of Radiation Oncology, Brigham and Women s Hospital and Dana Farber Cancer Institute, Boston, Massachusetts 02115, USA
    J Urol 173:1572-6. 2005
    ..We determined whether prostate specific antigen (PSA) velocity can serve as surrogate end point for prostate cancer specific mortality (PCSM) in patients with nonmetastatic, hormone refractory prostate cancer...
  6. ncbi request reprint Short- vs long-term androgen suppression plus external beam radiation therapy and survival in men of advanced age with node-negative high-risk adenocarcinoma of the prostate
    Anthony V D'Amico
    Department of Radiation Oncology, Brigham and Women s Hospital, Dana Farber Cancer Institute, Boston, Massachusetts, USA
    Cancer 109:2004-10. 2007
    ....
  7. ncbi request reprint Time to an undetectable prostate-specific antigen (PSA) after androgen suppression therapy for postoperative or postradiation PSA recurrence and prostate cancer-specific mortality
    Anthony V D'Amico
    Department of Radiation Oncology, Brigham and Women s Hospital and Dana Farber Cancer Institute, Boston, Massachusetts, USA
    Cancer 109:1290-5. 2007
    ....
  8. ncbi request reprint Pretreatment PSA velocity and risk of death from prostate cancer following external beam radiation therapy
    Anthony V D'Amico
    Department of Radiation Oncology, Brigham and Women s Hospital and Dana Farber Cancer Institute, Boston, Mass 02215, USA
    JAMA 294:440-7. 2005
    ..Men with localized prostate cancer and a preoperative prostate-specific antigen (PSA) velocity greater than 2.0 ng/mL per year experience a 10-fold increase in prostate cancer-specific mortality despite surgery...
  9. ncbi request reprint Identifying patients at risk for significant versus clinically insignificant postoperative prostate-specific antigen failure
    Anthony V D'Amico
    Brigham and Women s Hospital, Department of Radiation Oncology, Dana Faber Cancer Institute, Harvard Medical School, Boston, MA 02115, USA
    J Clin Oncol 23:4975-9. 2005
    ..We evaluated whether men at risk for significant versus clinically insignificant prostate-specific antigen (PSA) failure after radical prostatectomy could be identified using information available at diagnosis...
  10. ncbi request reprint Prostate-specific antigen response duration and risk of death for patients with hormone-refractory metastatic prostate cancer
    Anthony V D'Amico
    Department of Radiation Oncology, Brigham and Women s Hospital, Dana Farber Cancer Institute, Boston, Massachusetts, USA
    Urology 66:571-6. 2005
    ....
  11. ncbi request reprint Effect of 1 mg/day finasteride on concentrations of serum prostate-specific antigen in men with androgenic alopecia: a randomised controlled trial
    Anthony V D'Amico
    Department of Radiation Oncology, Brigham and Women s Hospital and Dana Faber Cancer Institute, Boston, MA 02215, USA
    Lancet Oncol 8:21-5. 2007
    ..We aimed to assess the effect of 1 mg/day finasteride on serum PSA in men aged 40-60 years with male-pattern hair loss...
  12. ncbi request reprint Identifying men diagnosed with clinically localized prostate cancer who are at high risk for death from prostate cancer
    Anthony V D'Amico
    Department of Radiation Oncology, Brigham and Women s Hospital and Dana Farber Cancer Institute, 75 Francis Street, Boston, MA 02215, USA
    J Urol 176:S11-5. 2006
    ..We identified factors at diagnosis that are significantly associated with time to prostate cancer specific mortality following radical prostatectomy or external beam radiation therapy...
  13. ncbi request reprint A prospective evaluation of rectal bleeding after dose-escalated three-dimensional conformal radiation therapy using an intrarectal balloon for prostate gland localization and immobilization
    Anthony V D'Amico
    Department of Radiation Oncology, Brigham and Women s Hospital, Dana Farber Cancer Institute, Boston, Massachusetts, USA
    Urology 67:780-4. 2006
    ....
  14. ncbi request reprint Predictors of mortality after prostate-specific antigen failure
    Anthony V D'Amico
    Department of Radiation Oncology, Brigham and Women s Hospital and Dana Farber Cancer Institute, Boston, MA, USA
    Int J Radiat Oncol Biol Phys 65:656-60. 2006
    ..We identified factors associated with the length of survival after prostate-specific antigen (PSA) failure...
  15. ncbi request reprint Preoperative PSA velocity and the risk of death from prostate cancer after radical prostatectomy
    Anthony V D'Amico
    Brigham and Women s Hospital and Dana Farber Cancer Institute, Boston, USA
    N Engl J Med 351:125-35. 2004
    ..We evaluated whether men at risk for death from prostate cancer after radical prostatectomy can be identified using information available at diagnosis...
  16. ncbi request reprint Intermediate end point for prostate cancer-specific mortality following salvage hormonal therapy for prostate-specific antigen failure
    Anthony V D'Amico
    Department of Radiation Oncology, Brigham and Women s Hospital and Dana Farber Cancer Institute, Boston, MA 02115, USA
    J Natl Cancer Inst 96:509-15. 2004
    ....
  17. ncbi request reprint Six-month androgen suppression plus radiation therapy compared with radiation therapy alone for men with prostate cancer and a rapidly increasing pretreatment prostate-specific antigen level
    Anthony V D'Amico
    Department of Radiation Oncology, Brigham and Women s Hospital and Dana Farber Cancer Institute, Boston, MA 02215, USA
    J Clin Oncol 24:4190-5. 2006
    ....
  18. ncbi request reprint Initial decline in hemoglobin during neoadjuvant hormonal therapy predicts for early prostate specific antigen failure following radiation and hormonal therapy for patients with intermediate and high-risk prostate cancer
    Anthony V D'Amico
    Department of Radiation Oncology, Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
    Cancer 95:275-80. 2002
    ....
  19. ncbi request reprint Biochemical outcome after radical prostatectomy or external beam radiation therapy for patients with clinically localized prostate carcinoma in the prostate specific antigen era
    Anthony V D'Amico
    Department of Radiation Oncology, Brigham and Women s Hospital and Dana Farber Cancer Institute, Boston, Massachusetts 02115, USA
    Cancer 95:281-6. 2002
    ....
  20. ncbi request reprint Radiation and hormonal therapy for locally advanced and clinically localized prostate cancer
    Anthony V D'Amico
    Department of Radiation Oncology, Brigham and Women s Hospital and Dana Farber Cancer Institute, Boston, Massachusetts 02115, USA
    Urology 60:32-7; discussion 37-8. 2002
    ..Validation of this predictive factor by others is needed...
  21. ncbi request reprint Changing prostate-specific antigen outcome after surgery or radiotherapy for localized prostate cancer during the prostate-specific antigen era
    Anthony V D'Amico
    Department of Radiation Oncology, Brigham and Women s Hospital and Dana Farber Cancer Institute, Boston, MA 02115, USA
    Int J Radiat Oncol Biol Phys 54:436-41. 2002
    ..To evaluate the change in prostate-specific antigen (PSA) outcome after radical prostatectomy (RP) or external beam radiotherapy (EBRT), controlling for follow-up during the PSA era...
  22. ncbi request reprint Determinants of prostate cancer-specific survival after radiation therapy for patients with clinically localized prostate cancer
    Anthony V D'Amico
    Department of Radiation Oncology, Brigham and Women s Hospital and Dana Farber Cancer Institute, Boston, MA 02215, USA
    J Clin Oncol 20:4567-73. 2002
    ..Identifying pretreatment and posttreatment predictors of time to prostate cancer-specific death (PCSD) after external-beam radiation therapy (RT) was the subject of this study...
  23. ncbi request reprint Advanced age at diagnosis is an independent predictor of time to death from prostate carcinoma for patients undergoing external beam radiation therapy for clinically localized prostate carcinoma
    Anthony V D'Amico
    Department of Radiation Oncology, Brigham and Women s Hospital and Dana Farber Cancer Institute, 75 Francis Street, L 2 Level, Boston, MA 02115, USA
    Cancer 97:56-62. 2003
    ....
  24. ncbi request reprint Cancer-specific mortality after surgery or radiation for patients with clinically localized prostate cancer managed during the prostate-specific antigen era
    Anthony V D'Amico
    Department of Radiation Oncology, Brigham and Women s Hospital and Dana Farber Cancer Institute, Boston, MA 02215, USA
    J Clin Oncol 21:2163-72. 2003
    ..To determine whether pretreatment risk groups shown to predict time to prostate cancer-specific mortality (PCSM) after treatment at a single institution retained that ability in a multi-institutional setting...
  25. ncbi request reprint Influence of androgen suppression therapy for prostate cancer on the frequency and timing of fatal myocardial infarctions
    Anthony V D'Amico
    Departments of Radiation Oncology and Medicine, Cardiovascular Division, Brigham and Women s Hospital and Lank Center for Genitourinary Oncology, Dana Farber Cancer Institute, Boston, MA 02215, USA
    J Clin Oncol 25:2420-5. 2007
    ..We evaluated whether the timing of fatal myocardial infarction (MI) was influenced by the administration of androgen suppression therapy (AST)...
  26. ncbi request reprint Surrogate end point for prostate cancer-specific mortality after radical prostatectomy or radiation therapy
    Anthony V D'Amico
    Department of Radiation Oncology, Brigham and Women s Hospital and Dana Farber Cancer Institute, Boston, MA 02215, USA
    J Natl Cancer Inst 95:1376-83. 2003
    ..Therefore, we evaluated the hypothesis that a short post-treatment PSA doubling time (PSA-DT) after radiation therapy is a surrogate end point for prostate cancer-specific mortality by analyzing two multi-institutional databases...
  27. ncbi request reprint Determinants of prostate cancer specific survival following radiation therapy during the prostate specific antigen era
    Anthony V D'Amico
    Department of Radiation Oncology, Dana Farber Cancer Institute, Brigham and Women s Hospital, Boston, MA 02215, USA
    J Urol 170:S42-6; discussion S46-7. 2003
    ..Identifying pretreatment and posttreatment predictors of time to prostate cancer specific death (PCSD) following external beam radiation therapy (RT) is the subject of this study...
  28. ncbi request reprint The impact of a delay in initiating radiation therapy on prostate-specific antigen outcome for patients with clinically localized prostate carcinoma
    Paul L Nguyen
    Department of Radiation Oncology, Brigham and Women s Hospital, Dana Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts 02115, USA
    Cancer 103:2053-9. 2005
    ..4 Gy for clinically localized prostate cancer between 1992 and 2001, were studied...
  29. ncbi request reprint Identification of comorbidities that place men at highest risk of death from androgen deprivation therapy before brachytherapy for prostate cancer
    Arti Parekh
    Department of Radiation Oncology, Dana Farber Brigham and Women s Hospital, Harvard Medical School, Boston, MA
    Brachytherapy 12:415-21. 2013
    ..To determine which specific comorbidities predispose men to excess mortality by androgen deprivation therapy (ADT) given before and during brachytherapy for prostate cancer...
  30. doi request reprint Reduced penile size and treatment regret in men with recurrent prostate cancer after surgery, radiotherapy plus androgen deprivation, or radiotherapy alone
    Arti Parekh
    Department of Radiation Oncology, Dana Farber Cancer Institute, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    Urology 81:130-4. 2013
    ..To report the relative incidence of the perceived reduction in penile size across prostate cancer treatment modalities and to describe its effect on quality of life and treatment regret...
  31. ncbi request reprint Androgen deprivation therapy for localized prostate cancer and the risk of cardiovascular mortality
    Henry K Tsai
    Harvard Radiation Oncology Program, Harvard Medical School, Boston, MA 02215, USA
    J Natl Cancer Inst 99:1516-24. 2007
    ..We investigated whether androgen deprivation therapy (ADT) use is associated with an increased risk of death from cardiovascular causes in patients treated for localized prostate cancer...
  32. doi request reprint Total androgen blockade versus a luteinizing hormone-releasing hormone agonist alone in men with high-risk prostate cancer treated with radiotherapy
    Akash Nanda
    Harvard Radiation Oncology Program, Brigham and Women s Hospital Dana Farber Cancer Institute, Boston, MA 02115, USA
    Int J Radiat Oncol Biol Phys 76:1439-44. 2010
    ..a luteinizing hormone-releasing hormone (LHRH) agonist alone affects the risk of prostate cancer-specific mortality (PCSM) in men with localized but high-risk disease treated with radiotherapy...
  33. doi request reprint Evaluating the combined effect of comorbidity and prostate-specific antigen kinetics on the risk of death in men after prostate-specific antigen recurrence
    Jennifer Y Wo
    Harvard Radiation Oncology Program, Harvard Medical School, Boston, MA, USA
    J Clin Oncol 27:6000-5. 2009
    ....
  34. doi request reprint Comorbidity, body mass index, and age and the risk of nonprostate-cancer-specific mortality after a postradiation prostate-specific antigen recurrence
    Paul L Nguyen
    Department of Radiation Oncology, Dana Farber Cancer Institute and Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
    Cancer 116:610-5. 2010
    ..Therefore, our ability to determine who would benefit from salvage hormonotherapy (HT) would be enhanced if an individual's risk of nonprostate-cancer-specific mortality were known...
  35. ncbi request reprint Comparing PSA outcome after radical prostatectomy or magnetic resonance imaging-guided partial prostatic irradiation in select patients with clinically localized adenocarcinoma of the prostate
    Anthony V D'Amico
    Department of Radiation Oncology, Brigham and Women s Hospital and Dana Farber Cancer Institute, Boston, Massachusetts 02115, USA
    Urology 62:1063-7. 2003
    ....
  36. ncbi request reprint Lower prostate specific antigen outcome than expected following radical prostatectomy in patients with high grade prostate and a prostatic specific antigen level of 4 ng/ml. Or less
    Anthony V D'Amico
    Department of Radiation Oncology, Brigham and Women s Hospital and Dana Farber Cancer Institute, Boston, MA, USA
    J Urol 167:2025-30; discussion 2030-1. 2002
    ....
  37. doi request reprint Interval to testosterone recovery after hormonal therapy for prostate cancer and risk of death
    Anthony V D'Amico
    Department of Radiation Oncology, Brigham and Women s Hospital and Dana Farber Cancer Institute, Boston, MA 02215, USA
    Int J Radiat Oncol Biol Phys 75:10-5. 2009
    ..To assess whether the risk of death is associated with the time to testosterone recovery (TTR) after radiotherapy (RT) and hormonal therapy (HT) for prostate cancer (PCa)...
  38. doi request reprint Radiation with or without 6 months of androgen suppression therapy in intermediate- and high-risk clinically localized prostate cancer: a postrandomization analysis by risk group
    Paul L Nguyen
    Department of Radiation Oncology, Dana Farber Cancer Institute and Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
    Int J Radiat Oncol Biol Phys 77:1046-52. 2010
    ..RT alone in men with unfavorable risk localized prostate cancer (PCa), but it is unknown if this benefit applies to all risk subgroups and, in particular, the intermediate-risk group...
  39. doi request reprint Impact of postoperative prostate-specific antigen disease recurrence and the use of salvage therapy on the risk of death
    Toni K Choueiri
    Department of Medical Oncology, Dana Farber Cancer Institute, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
    Cancer 116:1887-92. 2010
    ..BCR) as a time-dependent covariate (t) after radical prostatectomy (RP) for prostate cancer was associated with the risk of death and whether salvage therapy with radiotherapy (RT) and/or hormonal therapy (HT) can lessen this risk..
  40. doi request reprint Population-based determinants of radical prostatectomy surgical margin positivity
    Stephen B Williams
    Division of Urologic Surgery, Center for Surgery and Public Health, Dana Farber Cancer Institute, Department of Radiation Oncology, Brigham and Women s Hospital, Boston, MA 02115, USA
    BJU Int 107:1734-40. 2011
    ..Prognosis (cohort)...
  41. doi request reprint Race and survival following brachytherapy-based treatment for men with localized or locally advanced adenocarcinoma of the prostate
    Karen M Winkfield
    Harvard Radiation Oncology Program, Harvard Medical School, Boston, Massachusetts, USA
    Int J Radiat Oncol Biol Phys 81:e345-50. 2011
    ....
  42. ncbi request reprint Pretreatment predictors of time to cancer specific death after prostate specific antigen failure
    Anthony V D'Amico
    Department of Radiation Oncology, Brigham and Women s Hospital and Dana Farber Cancer Institute, Boston, Massachusetts, USA
    J Urol 169:1320-4. 2003
    ....
  43. doi request reprint Cardiovascular comorbidity and treatment regret in men with recurrent prostate cancer
    Paul L Nguyen
    Department of Radiation Oncology, Dana Farber Cancer Institute and Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    BJU Int 110:201-5. 2012
    ....
  44. doi request reprint Coronary revascularization and mortality in men with congestive heart failure or prior myocardial infarction who receive androgen deprivation
    Paul L Nguyen
    Department of Radiation Oncology, Dana Farber Cancer Institute, Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
    Cancer 117:406-13. 2011
    ....
  45. ncbi request reprint Patient-reported quality of life after salvage brachytherapy for radio-recurrent prostate cancer: A prospective Phase II study
    Paul L Nguyen
    Harvard Radiation Oncology Program, Boston, MA 02115, USA
    Brachytherapy 8:345-52. 2009
    ..Patient-reported quality of life (QOL) after salvage brachytherapy for radiorecurrent prostate cancer has not been well-characterized prospectively...
  46. ncbi request reprint Prostate-specific antigen nadir and cancer-specific mortality following hormonal therapy for prostate-specific antigen failure
    Alexandra J Stewart
    Brigham and Women s Hospital, Dana Faber Cancer Institute, Harvard Medical School, Boston, MA 02115, USA
    J Clin Oncol 23:6556-60. 2005
    ..2 ng/mL was significantly associated with prostate cancer-specific mortality (PCSM)...
  47. doi request reprint Biopsy Gleason score and the duration of testosterone suppression among men treated with external beam radiation and 6 months of combined androgen blockade
    Neil E Martin
    Department of Radiation Oncology, Dana Farber Cancer Institute and Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    BJU Int 110:1252-6. 2012
    ..In this study, we found that among men treated with 6 months of combined androgen blockade and radiation therapy, higher biopsy Gleason grade was associated with a shorter time to testosterone normalization...
  48. ncbi request reprint Multidisciplinary care and pursuit of active surveillance in low-risk prostate cancer
    Ayal A Aizer
    Harvard Radiation Oncology Program, Massachusetts General Hospital, Department of Radiation Oncology, 100 Blossom St, Cox 3, Boston, MA 02114, USA
    J Clin Oncol 30:3071-6. 2012
    ..The purpose of this study was to determine whether consultation at a multidisciplinary clinic is associated with selection of active surveillance in patients with low-risk prostate cancer...
  49. doi request reprint The number of high-risk factors and the risk of prostate cancer-specific mortality after brachytherapy: implications for treatment selection
    Daniel A Wattson
    Harvard Radiation Oncology Program, Department of Radiation Oncology, Brigham and Women s Hospital, 75 Francis Street, Boston, MA 02115, USA
    Int J Radiat Oncol Biol Phys 82:e773-9. 2012
    ....
  50. doi request reprint Influence of androgen deprivation therapy on all-cause mortality in men with high-risk prostate cancer and a history of congestive heart failure or myocardial infarction
    Paul L Nguyen
    Department of Radiation Oncology, Dana Farber Cancer Institute, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02215, USA
    Int J Radiat Oncol Biol Phys 82:1411-6. 2012
    ....
  51. doi request reprint Survival following radiation and androgen suppression therapy for prostate cancer in healthy older men: implications for screening recommendations
    Paul L Nguyen
    Harvard Radiation Oncology Program, Department of Radiation Oncology, Brigham and Women s Hospital, Boston, MA 02115, USA
    Int J Radiat Oncol Biol Phys 76:337-41. 2010
    ..The U.S. Preventive Services Task Force has recommended against screening men over 75 for prostate cancer. We examined whether older healthy men could benefit from aggressive prostate cancer treatment...
  52. doi request reprint Predictors of prostate cancer-specific mortality in elderly men with intermediate-risk prostate cancer treated with brachytherapy with or without external beam radiation therapy
    Akash Nanda
    Harvard Radiation Oncology Program, Brigham and Women s Hospital Dana Farber Cancer Institute, Boston, MA 02115, USA
    Int J Radiat Oncol Biol Phys 77:147-52. 2010
    ....
  53. ncbi request reprint Prostate cancer-specific mortality and the extent of therapy in healthy elderly men with high-risk prostate cancer
    Karen E Hoffman
    Department of Radiation Oncology, Brigham and Women s Hospital and Dana Farber Cancer Institute, Boston, Massachusetts, USA
    Cancer 116:2590-5. 2010
    ..The authors of this report compared the use of brachytherapy alone with combined brachytherapy, external-beam radiation to the prostate and seminal vesicles, and androgen-suppression therapy (CMT) in this population...
  54. doi request reprint Risk of all-cause and prostate cancer-specific mortality after brachytherapy in men with small prostate size
    Paul L Nguyen
    Department of Radiation Oncology, Dana Farber Cancer Institute and Brigham and Women s Hospital, Boston, MA 02115, USA
    Int J Radiat Oncol Biol Phys 79:1318-22. 2011
    ..Brachytherapy for prostate cancer can be technically challenging in men with small prostates (≤20 cc), but it is unknown whether their outcomes are different than those of men with larger prostates...
  55. ncbi request reprint Quantifying the impact of seminal vesicle invasion identified using endorectal magnetic resonance imaging on PSA outcome after radiation therapy for patients with clinically localized prostate cancer
    Paul L Nguyen
    Department of Radiation Oncology, Brigham and Women s Hospital, Dana Farber Cancer Institute and Harvard Medical School, Boston, MA 02115, USA
    Int J Radiat Oncol Biol Phys 59:400-5. 2004
    ....
  56. doi request reprint Salvage radiation in men after prostate-specific antigen failure and the risk of death
    Shane E Cotter
    Harvard Radiation Oncology Program, Brigham and Women s Hospital Dana Farber Cancer Institute, Boston, Massachusetts, USA
    Cancer 117:3925-32. 2011
    ..Whether such a benefit exits in men with a protracted PSA rise in DT (≥ 6 months) is unclear and was examined in the current study...
  57. doi request reprint The use of supplemental external beam radiotherapy in men with low-risk prostate cancer undergoing brachytherapy before and after the 1999 American Brachytherapy Society Guideline statement
    Arthur K Cheung
    Department of Radiation Oncology, Brigham and Women s Hospital and Dana Farber Cancer Institute, Boston, MA 02115, USA
    Brachytherapy 9:145-50. 2010
    ..We investigated the patterns of care in the community in this patient population before and after the reporting of the ABS guideline...
  58. ncbi request reprint Acute gastrointestinal, genitourinary, and dermatological toxicity during dose-escalated 3D-conformal radiation therapy (3DCRT) using an intrarectal balloon for prostate gland localization and immobilization
    Rosemonde Woel
    Joint Center for Radiation Therapy, Brigham and Women s Hospital and Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02115, USA
    Int J Radiat Oncol Biol Phys 62:392-6. 2005
    ..A modified intrarectal balloon (Medrad) was used for prostate gland localization and immobilization...
  59. ncbi request reprint Cancer-specific mortality after radiation therapy with short-course hormonal therapy or radical prostatectomy in men with localized, intermediate-risk to high-risk prostate cancer
    Henry K Tsai
    Harvard Radiation Oncology Program, Harvard Medical School, Boston, Massachusetts, USA
    Cancer 107:2597-603. 2006
    ..The authors estimated PCSM after radiation therapy with short-course androgen suppression therapy (RT+AST) or radical prostatectomy (RP) in men with clinically localized, intermediate-risk to high-risk prostate cancer...
  60. ncbi request reprint Duration of testosterone suppression and the risk of death from prostate cancer in men treated using radiation and 6 months of hormone therapy
    Anthony V D'Amico
    Department of Radiation Oncology, Brigham and Women s Hospital and Dana Farber Cancer Institute, Boston, Massachusetts 02215, USA
    Cancer 110:1723-8. 2007
    ..The authors evaluated whether the duration of androgen suppression (AS) after the completion of hormone therapy (HT) was associated with the risk of prostate cancer-specific mortality (PCSM) and all-cause mortality (ACM)...
  61. ncbi request reprint Late genitourinary and gastrointestinal toxicity after magnetic resonance image-guided prostate brachytherapy with or without neoadjuvant external beam radiation therapy
    Michele Albert
    Department of Radiation Oncology, Brigham and Women s Hospital, 75 Francis Street, L 2 Level, Boston, MA 02115, USA
    Cancer 98:949-54. 2003
    ..This study was designed to estimate the rates of late genitourinary (GU) and rectal toxicity after magnetic resonance image (MRI)-guided prostate brachytherapy exclusively or in conjunction with external beam radiation therapy (EBRT)...
  62. ncbi request reprint Risk of prostate cancer recurrence in men treated with radiation alone or in conjunction with combined or less than combined androgen suppression therapy
    Anthony V D'Amico
    Department of Radiation, Brigham and Women s Hospital and Dana Farber Cancer Institute, Boston, MA 02215, USA
    J Clin Oncol 26:2979-83. 2008
    ..We determined the risk of recurrence in men enrolled on a randomized trial for prostate cancer who were treated with radiation therapy (RT) alone or in conjunction with combined or less than combined androgen suppression therapy (AST)...
  63. ncbi request reprint Predictors of prostate cancer-specific mortality after radical prostatectomy or radiation therapy
    Ping Zhou
    Department of Radiation Oncology, Brigham and Women s Hospital and Dana Farber Cancer Institute, Boston, MA, USA
    J Clin Oncol 23:6992-8. 2005
    ..We evaluated predictors of prostate cancer-specific mortality (PCSM) after prostate-specific antigen (PSA) failure after radical prostatectomy (RP) or radiation therapy (RT)...
  64. doi request reprint Maximum vs. mono androgen blockade and the risk of recurrence in men with localized prostate cancer undergoing brachytherapy
    Ronald C Chen
    Harvard Radiation Oncology Program, Harvard Medical School, Boston, MA, USA
    Int J Radiat Oncol Biol Phys 75:36-9. 2009
    ..We examined whether maximum androgen blockade (MAB) is associated with a decreased recurrence risk vs. single-agent androgen suppression (monotherapy) for men undergoing brachytherapy (BT) for localized prostate cancer...
  65. doi request reprint Androgen suppression and radiation vs radiation alone for prostate cancer: a randomized trial
    Anthony V D'Amico
    Department of Radiation Oncology, Brigham and Women s Hospital and Dana Farber Cancer Institute, Boston, Massachusetts 02115, USA
    JAMA 299:289-95. 2008
    ..Comorbidities may increase the negative effects of specific anticancer treatments such as androgen suppression therapy (AST)...
  66. ncbi request reprint Invasion of seminal vesicles by adenocarcinoma of the prostate: PSA outcome determined by preoperative and postoperative factors
    Keith D Bloom
    Division of Urology, Brigham and Women s Hospital, Boston, Massachusetts, USA
    Urology 63:333-6. 2004
    ..SVI by prostate cancer is associated with high PSA failure rates after RRP and subsequent distant metastases...
  67. ncbi request reprint Magnetic resonance image-guided salvage brachytherapy after radiation in select men who initially presented with favorable-risk prostate cancer: a prospective phase 2 study
    Paul L Nguyen
    Department of Radiation Oncology, Brigham and Women s Hospital and Dana Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts
    Cancer 110:1485-92. 2007
    ....
  68. doi request reprint Type of diabetes mellitus and the odds of Gleason score 8 to 10 prostate cancer
    Josephine Kang
    Harvard Radiation Oncology Program, Brigham and Women s Hospital, Department of Radiation Oncology, Boston, MA 02115, USA
    Int J Radiat Oncol Biol Phys 82:e463-7. 2012
    ..In this study we evaluated whether DM Type 1, 2, or both are associated with high-grade PCa after adjusting for known predictors of high-grade disease...
  69. ncbi request reprint Prostate cancer-specific mortality after radical prostatectomy or external beam radiation therapy in men with 1 or more high-risk factors
    Anthony V D'Amico
    Department of Radiation Oncology, Brigham and Women s Hospital and Dana Farber Cancer Institute, Boston, Massachusetts 02215, USA
    Cancer 110:56-61. 2007
    ..Estimates of prostate cancer-specific mortality (PCSM) were determined after radical prostatectomy (RP) or radiation therapy (RT) in men with >or=1 high-risk factors...
  70. doi request reprint Predicting the risk of pelvic node involvement among men with prostate cancer in the contemporary era
    Paul L Nguyen
    Harvard Radiation Oncology Program, Boston, MA, USA
    Int J Radiat Oncol Biol Phys 74:104-9. 2009
    ..We examined the accuracy of this formula in contemporary patients...
  71. doi request reprint Hormonal therapy use for prostate cancer and mortality in men with coronary artery disease-induced congestive heart failure or myocardial infarction
    Akash Nanda
    Harvard Radiation Oncology Program, Brigham and Women s Hospital Dana Farber Cancer Institute, 75 Francis St, ASB1 L2, Boston, MA 02115, USA
    JAMA 302:866-73. 2009
    ..However, it is unknown which comorbid conditions eliminate this survival benefit...
  72. doi request reprint Predicting prostate cancer mortality among men with intermediate to high-risk disease and multiple unfavorable risk factors
    Paul L Nguyen
    Harvard Radiation Oncology Program, Boston, MA 02115, USA
    Int J Radiat Oncol Biol Phys 73:659-64. 2009
    ..To determine whether the number of unfavorable risk factors could be used to predict the risk of prostate cancer-specific mortality (PCSM) among men with intermediate- to high-risk prostate cancer...
  73. doi request reprint Surrogate endpoints for prostate cancer-specific mortality after radiotherapy and androgen suppression therapy in men with localised or locally advanced prostate cancer: an analysis of two randomised trials
    Anthony V D'Amico
    Department of Radiation Oncology, Brigham and Women s Hospital and Dana Farber Cancer Institute, Boston, MA 02115, USA
    Lancet Oncol 13:189-95. 2012
    ..Thus, we assessed whether prostate-specific antigen (PSA) values can act as an early surrogate for prostate cancer-specific mortality (PCSM)...
  74. ncbi request reprint Perineural invasion associated with increased cancer-specific mortality after external beam radiation therapy for men with low- and intermediate-risk prostate cancer
    Clair Beard
    Department of Radiation Oncology, Dana Farber Cancer Institute and Brigham and Women s Hospital, Boston, MA 02115, USA
    Int J Radiat Oncol Biol Phys 66:403-7. 2006
    ..To identify an association between perineural invasion (PNI) and cancer-specific survival in patients with prostate cancer after standard-dose external beam radiation therapy (RT)...
  75. ncbi request reprint Patient-reported acute gastrointestinal toxicity in men receiving 3-dimensional conformal radiation therapy for prostate cancer with or without neoadjuvant androgen suppression therapy
    Henry K Tsai
    Department of Radiation Oncology, Dana Farber Cancer Institute and Brigham and Women s Hospital, Boston, MA 02115, USA
    Urol Oncol 23:230-7. 2005
    ..To investigate the impact of 2 months of neoadjuvant and 2 months of concurrent hormonal therapy on the acute gastrointestinal (GI) toxicities associated with 3-dimensional conformal radiation therapy (3D-CRT) for prostate adenocarcinoma...
  76. doi request reprint Mortality in men with localized prostate cancer treated with brachytherapy with or without neoadjuvant hormone therapy
    Amy M Dosoretz
    Department of Radiation Oncology, Harvard Radiation Oncology Program, Boston, Massachusetts 02115, USA
    Cancer 116:837-42. 2010
    ..Therefore, the objective of the current study was to examine the effect of NHT on the risk of ACM in men with prostate cancer who receive with brachytherapy...
  77. ncbi request reprint Patient selection, cancer control, and complications after salvage local therapy for postradiation prostate-specific antigen failure: a systematic review of the literature
    Paul L Nguyen
    Department of Radiation Oncology, Brigham and Women s Hospital and Dana Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts 02115, USA
    Cancer 110:1417-28. 2007
    ....
  78. ncbi request reprint Influence of body mass index on prostate-specific antigen failure after androgen suppression and radiation therapy for localized prostate cancer
    Jason A Efstathiou
    Department of Radiation Oncology, Brigham and Women s Hospital and Dana Farber Cancer Institute, Boston, Massachusetts 02115, USA
    Cancer 109:1493-8. 2007
    ..Whether BMI is associated with time to PSA failure was investigated in men treated with androgen suppression therapy (AST) and radiation therapy (RT) for clinically localized prostate cancer...
  79. doi request reprint Causes of death in men undergoing androgen suppression therapy for newly diagnosed localized or recurrent prostate cancer
    Anthony V D'Amico
    Department of Radiation Oncology, Brigham and Women s Hospital and Dana Farber Cancer Institute, Boston, MA 02215, USA
    Cancer 113:3290-7. 2008
    ..The authors estimated and characterized mortality after androgen suppression therapy (AST) use in men with newly diagnosed localized and recurrent prostate cancer...
  80. doi request reprint Time to prostate-specific antigen nadir after androgen suppression therapy for postoperative or postradiation PSA failure and risk of prostate cancer-specific mortality
    Christine S Chung
    Brigham and Women s Hospital, Dana Farber Cancer Institute, Boston, MA 02115, USA
    Urology 71:136-40. 2008
    ..2 ng/mL or less) after 8 months of androgen suppression therapy (AST)...
  81. doi request reprint Defining the rectal dose constraint for permanent radioactive seed implantation of the prostate
    Michele Albert
    Department of Radiation Oncology, Brigham and Women s Hospital and Dana Farber Cancer Institute, Boston, MA 02115, USA
    Urol Oncol 26:147-52. 2008
    ..This study was performed to define the rectal dose constraint that would predict late rectal bleeding requiring argon plasma coagulation (APC) following prostate brachy mono-therapy...
  82. doi request reprint p53 protein expression status and recurrence in men treated with radiation and androgen suppression therapy for higher-risk prostate cancer: a prospective phase II Cancer and Leukemia Group B Study (CALGB 9682)
    Anthony V D'Amico
    Department of Radiation Oncology, Brigham and Women s Hospital, Boston, Massachusetts 02215, USA
    Urology 71:933-7. 2008
    ..It has been hypothesized that abnormal p53 protein expression is associated with a worse prognosis after radiation (RT) and androgen suppression therapy (AST). This hypothesis was prospectively tested...
  83. doi request reprint Biochemical recurrence after radical prostatectomy for prevalent versus incident cases of prostate cancer : implications for management
    Paul L Nguyen
    Radiation Oncology Program, Harvard Medical School, Boston, Massachusetts 02115, USA
    Cancer 113:3146-52. 2008
    ....
  84. ncbi request reprint Salvage radiotherapy for biochemical failure of radical prostatectomy: a single-institution experience
    Stanley L Liauw
    Department of Radiation Oncology, University of Texas Southwestern Medical Center at Dallas, 75390 9110, USA
    Urology 61:1204-10. 2003
    ....