Research Topics
Species | Donald CutlipSummaryAffiliation: Harvard University Country: USA Publications
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Publications
Troponin criteria for myocardial infarction after percutaneous coronary interventionVictor Novack
Beth Israel Deaconess Medical Center, 330 Brookline Ave, Boston, MA 02215, USA
Arch Intern Med 172:502-8. 2012....
Drug-eluting stent era: will we improve 5-year outcomes?Donald E Cutlip
Interventional Cardiology Section, Beth Israel Deaconess Medical Center, Harvard Clinical Research Institute, Harvard Medical School, Boston, Massachusetts, USA
Coron Artery Dis 17:681-4. 2006....
Does creatinine kinase-MB elevation after percutaneous coronary intervention predict outcomes in 2005? Cardiac enzyme elevation after successful percutaneous coronary intervention is not an independent predictor of adverse outcomesDonald E Cutlip
Division of Cardiology, Beth Israel Deaconess Medical Center, Harvard Clinical Research Institute, Boston, MA, USA
Circulation 112:916-22; discussion 922. 2005
Clinical end points in coronary stent trials: a case for standardized definitionsDonald E Cutlip
Harvard Clinical Research Institute, Harvard Medical School, 930 Commonwealth Avenue, Boston, MA 02215, USA
Circulation 115:2344-51. 2007..Although most clinical trials of coronary stents have measured nominally identical safety and effectiveness end points, differences in definitions and timing of assessment have created confusion in interpretation...
Drug-eluting stent era: will we improve 5-year outcomes?Donald E Cutlip
Interventional Cardiology Section, Beth Israel Deaconess Medical Center, Harvard Clinical Research Institute, Harvard Medical School, Boston, Massachusetts 02215, USA
Coron Artery Dis 17:289-92. 2006....
Effect of tirofiban before primary angioplasty on initial coronary flow and early ST-segment resolution in patients with acute myocardial infarctionDonald E Cutlip
Interventional Cardiology Section, Beth Israel Deaconess Medical Center, Boston, Massacusetts 02215, USA
Am J Cardiol 92:977-80. 2003..20). Patients receiving early tirofiban treatment were more likely to achieve complete (>70%) ST-segment resolution at 90 minutes (69% vs 44%, p = 0.07)...
Autopsy validation study of the academic research consortium stent thrombosis definitionDonald E Cutlip
Cardiovascular Division, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02215, USA
JACC Cardiovasc Interv 4:554-9. 2011..This study sought to validate the sensitivity and specificity of the Academic Research Consortium's (ARC) classification of stent thrombosis...
In-hospital and 1-year outcomes among unselected percutaneous coronary intervention patients treated with either sirolimus- or paclitaxel-eluting stents: results from the EVENT (Evaluation of Drug Eluting Stents and Ischemic Events) registryVictor Novack
Harvard Clinical Research Institute, Boston, Massachusetts, USA
JACC Cardiovasc Interv 2:767-75. 2009..The aim of this study was to compare outcomes among unselected patients undergoing percutaneous coronary intervention (PCI) with either sirolimus-eluting (SES) or paclitaxel-eluting stents (PES)...
A pilot study examining the severity and outcome of the post-cardiac arrest syndrome: a comparative analysis of two geographically distinct hospitalsMichael W Donnino
Department of Emergency Medicine, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
Circulation 126:1478-83. 2012..We tested whether hospital-independent factors would account for the difference in outcome between 2 geographically distinct hospitals...
Impact of routine angiographic follow-up on the clinical benefits of paclitaxel-eluting stents: results from the TAXUS-IV trialDuane S Pinto
Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts 02115, USA
J Am Coll Cardiol 48:32-6. 2006....
Effect of diabetes mellitus on five-year clinical outcomes after single-vessel coronary stenting (a pooled analysis of coronary stent clinical trials)Tobias T Lee
Division of Cardiology, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA
Am J Cardiol 98:718-21. 2006....
Hospital delays in reperfusion for ST-elevation myocardial infarction: implications when selecting a reperfusion strategyDuane S Pinto
TIMI Study Group and the Cardiovascular Division, Department of Medicine, Beth Israel Deaconess Medical Center, 185 Pilgrim Rd, Boston, MA 02115, USA
Circulation 114:2019-25. 2006..As indicated in the American College of Cardiology/American Heart Association guidelines, both the hospital-based PPCI-related delay (DB-DN time) and patient characteristics should be considered when a reperfusion strategy is selected...
Stent thrombosis in randomized clinical trials of drug-eluting stentsLaura Mauri
Brigham and Women s Hospital, Boston, USA
N Engl J Med 356:1020-9. 2007..Definitions of stent thrombosis that have been used in clinical trials of drug-eluting stents have been restrictive and have not been used in a uniform manner...
Safety and efficacy of sirolimus- and paclitaxel-eluting coronary stentsGregg W Stone
Columbia University Medical Center and the Cardiovascular Research Foundation, New York, NY 10022, USA
N Engl J Med 356:998-1008. 2007..Such studies have been inconclusive because of their insufficient size, the use of historical controls, a limited duration of follow-up, and a lack of access to original source data...
Prevalence and prognostic significance of preprocedural cardiac troponin elevation among patients with stable coronary artery disease undergoing percutaneous coronary intervention: results from the evaluation of drug eluting stents and ischemic events regAllen Jeremias
Division of Cardiovascular Medicine, Stony Brook University Medical Center, Stony Brook, NY, USA
Circulation 118:632-8. 2008....
Offsetting impact of thrombosis and restenosis on the occurrence of death and myocardial infarction after paclitaxel-eluting and bare metal stent implantationGregg W Stone
Columbia University Medical Center, The Cardiovascular Research Foundation, 111 E 59th St, 11th Floor, New York, NY 10022, USA
Circulation 115:2842-7. 2007..We hypothesized that the prevention of restenosis-related adverse events by drug-eluting stents might offset some or all of the excess risk from ST...
Long-term clinical outcomes with sirolimus-eluting coronary stents: five-year results of the RAVEL trialMarie Claude Morice
Institut Cardiovasculaire Paris Sud, Massy, France
J Am Coll Cardiol 50:1299-304. 2007..This study examined the clinical outcomes at 5 years in RAVEL (A Randomized Comparison of a Sirolimus-Eluting Stent With a Standard Stent for Coronary Revascularization), the first controlled trial of drug-eluting stents...
Comparison of outcomes using sirolimus-eluting stenting in diabetic versus nondiabetic patients with comparison of insulin versus non-insulin therapy in the diabetic patientsRamon Kumar
Department of Medicine, Cardiology Division, Beth Israel Deaconess Medical Center, Boston, MA, USA
Am J Cardiol 100:1187-91. 2007....
Reduction in sex-based mortality difference with implementation of new cardiology guidelinesVictor Novack
Department of Medicine, Soroka University Medical Center, Beer Sheva, Israel
Am J Med 121:597-603.e1. 2008....
Saphenous vein graft stenting and major adverse cardiac events: a predictive model derived from a pooled analysis of 3958 patientsAlanna Coolong
Division of Cardiovascular Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Mass 02115, USA
Circulation 117:790-7. 2008..Although MACE rates are reduced significantly by the use of embolic protection devices (EPDs), neither the level of baseline risk nor the benefit provided by EPDs has been well characterized...
Differential outcomes after sirolimus-eluting stent implantation: comparing on-label versus off-label patients in the 'real world'Allen Jeremias
Division of Cardiovascular Medicine, Stony Brook University Medical Center, Stony Brook, NY 11794, USA
Coron Artery Dis 19:111-5. 2008..This study examined the performance of SES in a 'real world' setting by comparing the outcomes of trial-eligible versus ineligible patients undergoing percutaneous coronary intervention...
Clinical, procedural, and pharmacologic correlates of acute and subacute stent thrombosis: results of a multicenter case-control study with 145 thrombosis eventsMichael J Rinaldi
Beth Israel Deaconess Medical Center, Boston, MA, USA
Am Heart J 155:654-60. 2008....
Long-term results of carotid stenting versus endarterectomy in high-risk patientsHitinder S Gurm
University of Michigan School of Medicine, Ann Arbor, USA
N Engl J Med 358:1572-9. 2008..We now report the 3-year results...
Comparison of an everolimus-eluting stent and a paclitaxel-eluting stent in patients with coronary artery disease: a randomized trialGregg W Stone
Columbia University Medical Center, The Cardiovascular Research Foundation, 111 E 59th St, 11th Floor, New York, NY 10022, USA
JAMA 299:1903-13. 2008....
The Claudication: Exercise Vs. Endoluminal Revascularization (CLEVER) study: rationale and methodsTimothy P Murphy
Rhode Island Hospital Vascular Disease Research Center and Brown Medical School Department of Diagnostic Imaging, Providence, RI 02903, USA
J Vasc Surg 47:1356-63. 2008....
Two-year outcomes after sirolimus-eluting stent implantation: results from the Sirolimus-Eluting Stent in de Novo Native Coronary Lesions (SIRIUS) trialGiora Weisz
Cardiovascular Research Foundation and Columbia University Medical Center, New York, New York 10032, USA
J Am Coll Cardiol 47:1350-5. 2006....
Cost-effectiveness of distal embolic protection for patients undergoing percutaneous intervention of saphenous vein bypass grafts: results from the SAFER trialDavid J Cohen
Harvard Clinical Research Institute, Boston, Massachusetts, USA
J Am Coll Cardiol 44:1801-8. 2004..The goal of this research was to determine the incremental cost and cost-effectiveness of embolic protection in patients undergoing percutaneous revascularization (PCI) of diseased saphenous vein bypass grafts (SVGs)...
Protected carotid-artery stenting versus endarterectomy in high-risk patientsJay S Yadav
Cardiovascular Medicine, Cleveland Clinic Foundation, Cleveland, OH 44195, USA
N Engl J Med 351:1493-501. 2004..Stenting with the use of an emboli-protection device is a less invasive revascularization strategy than endarterectomy in carotid-artery disease...
Utility of the Safe-Cross-guided radiofrequency total occlusion crossing system in chronic coronary total occlusions (results from the Guided Radio Frequency Energy Ablation of Total Occlusions Registry Study)Donald S Baim
Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts 02120 1613, USA
Am J Cardiol 94:853-8. 2004..Based on these data, the device has been approved in Europe and was recently (January 2004) granted 510K clearance by the Food and Drug Administration...
Differential mortality risk of postprocedural creatine kinase-MB elevation following successful versus unsuccessful stent proceduresAllen Jeremias
Harvard Clinical Research Institute, Division of Cardiology, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
J Am Coll Cardiol 44:1210-4. 2004..001), but not periprocedural MI. CONCLUSIONS: The association of periprocedural MI with increased mortality during the first year following stent placement was confined to patients with unsuccessful procedures...
Beyond restenosis: five-year clinical outcomes from second-generation coronary stent trialsDonald E Cutlip
Harvard Clinical Research Institute, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
Circulation 110:1226-30. 2004....
Effects of stent length and lesion length on coronary restenosisLaura Mauri
Division of Clinical Biometrics, Brigham and Women's Hospital, 1620 Tremont Street, Boston, MA 02120, USA
Am J Cardiol 93:1340-6, A5. 2004..This analysis supports a conservative approach of matching stent length to lesion length to reduce the risk of restenosis with bare metal stents...
Drug-eluting stent task force: final report and recommendations of the working committees on cost-effectiveness/economics, access to care, and medicolegal issuesJohn McB Hodgson
MetroHealth Medical Center, Cleveland, Ohio 44109, USA
Catheter Cardiovasc Interv 62:1-17. 2004..The Task Force trusts that this report will be of value to the diverse constituencies involved with introduction of this important new technology...
Stent thrombosis after successful sirolimus-eluting stent implantationAllen Jeremias
Section of Interventional Cardiology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Mass, USA
Circulation 109:1930-2. 2004..The discontinuation of antiplatelet therapy was strongly associated with the development of ST in this patient population...
Clinical restenosis after coronary stenting: perspectives from multicenter clinical trialsDonald E Cutlip
Harvard Clinical Research Institute, Boston, Massachusetts 02215, USA
J Am Coll Cardiol 40:2082-9. 2002..We sought to evaluate clinical restenosis in a large population of patients who had undergone coronary stent placement...
Effect of gender on in-hospital and one-year outcomes after contemporary coronary artery stentingManish S Chauhan
Lahey Clinic Medical Center, Burlington, Massachsetts 01805, USA
Am J Cardiol 95:101-4. 2005....
Cutting balloon angioplasty for the prevention of restenosis: results of the Cutting Balloon Global Randomized TrialLaura Mauri
Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA
Am J Cardiol 90:1079-83. 2002..CB angioplasty should be reserved for difficult lesions in which controlled dilatation is believed to provide a better acute result compared with balloon angioplasty alone...
Geographical differences in the rates of angiographic restenosis and ischemia-driven target vessel revascularization after percutaneous coronary interventions: results from the Prevention of Restenosis With Tranilast and its Outcomes (PRESTO) TrialMandeep Singh
Division of Internal Medicine and Cardiovascular Diseases, Mayo Clinic and Mayo Foundation, Rochester, Minnesota 55905, USA
J Am Coll Cardiol 47:34-9. 2006..In the absence of a definitive clinical trial to support this view, how should the prudent, cutting-edge cardiologist proceed?..
Robustness of late lumen loss in discriminating drug-eluting stents across variable observational and randomized trialsLaura Mauri
Brigham and Women s Hospital, Boston, MA 02116, USA
Circulation 112:2833-9. 2005..We hypothesized that mean in-stent late loss might be a more stable estimator of restenosis propensity across such studies...
A pooled analysis of data comparing sirolimus-eluting stents with bare-metal stentsChristian Spaulding
Assistance Publique Hôpitaux de Paris Cochin Hospital, Paris 5 Medical School René Descartes University and INSERM Unité 780 Avenir, Paris
N Engl J Med 356:989-97. 2007..The long-term safety of drug-eluting stents has been questioned recently...
Randomized trial of a distal embolic protection device during percutaneous intervention of saphenous vein aorto-coronary bypass graftsDonald S Baim
Division of Cardiovascular Diseases, Brigham and Women s Hospital, Boston, Mass 02115, USA
Circulation 105:1285-90. 2002..We report the first multicenter randomized trial to evaluate use of a distal embolic protection device during stenting of such lesions...
Comparison of thrombosis and restenosis risk from stent length of sirolimus-eluting stents versus bare metal stentsLaura Mauri
Brigham and Women's Hospital, Boston, Massachusetts 02115, USA
Am J Cardiol 95:1140-5. 2005..Longer stent-to-lesion length strategies should be used only when a shorter stent is likely to result in incomplete lesion coverage and edge dissection, a strong determinant of stent thrombosis...
Relationship of late loss in lumen diameter to coronary restenosis in sirolimus-eluting stentsLaura Mauri
Brigham and Women's Hospital, Boston, Mass 02116, USA
Circulation 111:321-7. 2005..Late loss is monotonically correlated with the probability of restenosis and yields a more efficient estimate of the restenosis process in the era of lower binary restenosis rates...
Rheolytic thrombectomy and platelet glycoprotein IIb/IIIa blockade for stent thrombosisStephane Rinfret
Cardiovascular Division, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts 02215, USA
Catheter Cardiovasc Interv 57:24-30. 2002..A combined approach of rheolytic thrombectomy with adjunctive GP IIb/IIIa blockade was highly effective in resolving stent thrombosis and was associated with favorable acute and long-term outcomes...
Determinants of 30-day adverse events following saphenous vein graft intervention with and without a distal occlusion embolic protection deviceGregory R Giugliano
Division of Cardiology, Brigham and Women's Hospital, One Brigham Circle, Boston, MA 02115, USA
Am J Cardiol 95:173-7. 2005....
Incidence and predictors of late total occlusion following coronary stentingPinak B Shah
Cardiovascular Division, St Elizabeth s Medical Center, Boston, Massachusetts 02135, USA
Catheter Cardiovasc Interv 60:344-51. 2003..004), longer stent length (P < 0.001), and smaller preprocedure MLD (P = 0.012) were independent predictors of total occlusion following coronary stenting...
Comparison of rotational atherectomy with conventional balloon angioplasty in the prevention of restenosis of small coronary arteries: results of the Dilatation vs Ablation Revascularization Trial Targeting Restenosis (DART)Laura Mauri
Swedish Hospital, Seattle, Wash, USA
Am Heart J 145:847-54. 2003..Because the acute gain and loss index ratios of the 2 treatments were similar, there was no evident beneficial antirestenosis mechanism seen for rotational atherectomy...
Four-year clinical follow-up after implantation of the endeavor zotarolimus-eluting stent: ENDEAVOR I, the first-in-human studyIan T Meredith
Monash Medical Centre and Monash University, Melbourne, Australia
Am J Cardiol 100:56M-61M. 2007..The treatment of patients with symptomatic CAD due to de novo lesions in native coronary arteries with the Endeavor ZES has sustained clinical benefits to 4 years, with very low rates of MACE and TLR...
Risk of target lesion revascularization after coronary stenting in patients with and without chronic kidney diseaseDavid Charytan
Department of Medicine, Brigham and Women s Hospital, Renal Division, Clinical Biometrics, 1 Brigham Circle, 3rd Floor, Boston, MA 02115, USA
Nephrol Dial Transplant 22:2578-85. 2007..Whether mild to moderate chronic kidney disease (CKD) is associated with a similarly increased need for short or long-term target lesion revascularization (TLR) following coronary stenting is uncertain...
Drug eluting stents for ST-elevation myocardial infarction: risk and benefitJason Ryan
Beth Israel Deaconess Medical Center and Harvard Medical School, 1 Deaconess Road, Boston, MA 02215, USA
J Thromb Thrombolysis 24:293-9. 2007..This review with discuss the theoretical risks and benefits of DES for STEMI, the available data regarding their use, and the areas where future studies are needed...
Obesity and clinical restenosis after coronary stent placementJamal S Rana
Cardiovascular Division, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA
Am Heart J 150:821-6. 2005..The significant association of severe obesity in nondiabetic and normotensive patients suggests that other obesity-associated mechanisms such as insulin resistance and inflammation should be further explored...
Relationship of chronic kidney disease to cardiovascular death and myocardial infarction following coronary stentingDavid M Charytan
Department of Medicine, Brigham and Women s Hospital, Boston, Massachusetts 02120, USA
J Nephrol 19:764-70. 2006....
Gender-specific outcomes after sirolimus-eluting stent implantationEmilia Solinas
Columbia University Medical Center and the Cardiovascular Research Foundation, New York, New York, USA
J Am Coll Cardiol 50:2111-6. 2007..We examined the impact of gender on outcomes of patients undergoing percutaneous coronary intervention using sirolimus-eluting stents (SES)...
Research Grants
- Claudication Exercise vs Endoluminal RevascularizationDonald Cutlip; Fiscal Year: 2007..Recruitment will be done over 28 months and patients will be followed for 18 months; the total study duration will be 5 years. ..
