J P Culver

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. ncbi request reprint A quantitative comparison of simultaneous BOLD fMRI and NIRS recordings during functional brain activation
    Gary Strangman
    Neural Systems Group, NMR Center, Massachusetts General Hospital Harvard Medical School, Harvard MIT Division of Health Sciences and Technology, Charlestown 02129, USA
    Neuroimage 17:719-31. 2002
  2. ncbi request reprint Quantitative small animal fluorescence tomography using an ultrafast gated image intensifier
    Sachin V Patwardhan
    Dept of Radiol, Washington Univ Sch of Med, St Louis, MO 63110, USA
    Conf Proc IEEE Eng Med Biol Soc 1:2675-8. 2006
  3. ncbi request reprint Volumetric diffuse optical tomography of brain activity
    Joseph P Culver
    Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts 02129, USA
    Opt Lett 28:2061-3. 2003
  4. ncbi request reprint Diffuse optical tomography of cerebral blood flow, oxygenation, and metabolism in rat during focal ischemia
    Joseph P Culver
    Department of Physics and Astronomy, Cerebrovascular Research Center, University of Pennsylvania, Philadelphia, Pennsylvania, U S A
    J Cereb Blood Flow Metab 23:911-24. 2003
  5. ncbi request reprint Three-dimensional diffuse optical tomography in the parallel plane transmission geometry: evaluation of a hybrid frequency domain/continuous wave clinical system for breast imaging
    J P Culver
    Department of Physics and Astronomy, University of Pennsylvania, Philadelphia, Pennsylvania 19104 6396, USA
    Med Phys 30:235-47. 2003
  6. ncbi request reprint Bulk optical properties of healthy female breast tissue
    T Durduran
    Department of Physics and Astronomy, University of Pennsylvania, Philadelphia 19104, USA
    Phys Med Biol 47:2847-61. 2002
  7. ncbi request reprint Near-field diffraction tomography with diffuse photon density waves
    X Li
    Department of Physics and Astronomy, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    Phys Rev E Stat Phys Plasmas Fluids Relat Interdiscip Topics 61:4295-309. 2000
  8. ncbi request reprint Can the cerebral metabolic rate of oxygen be estimated with near-infrared spectroscopy?
    D A Boas
    Athinoula A Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA
    Phys Med Biol 48:2405-18. 2003
  9. ncbi request reprint In vivo cerebrovascular measurement combining diffuse near-infrared absorption and correlation spectroscopies
    C Cheung
    Department of Physics and Astronomy, University of Pennsylvania, Philadelphia 19104, USA
    Phys Med Biol 46:2053-65. 2001
  10. doi request reprint Quantitative diffuse optical tomography for small animals using an ultrafast gated image intensifier
    Sachin V Patwardhan
    Washington University School of Medicine, Department of Radiology, Mallinckrodt Institute of Radiology, St Louis, Missouri 63110, USA
    J Biomed Opt 13:011009. 2008

Detail Information

Publications20

  1. ncbi request reprint A quantitative comparison of simultaneous BOLD fMRI and NIRS recordings during functional brain activation
    Gary Strangman
    Neural Systems Group, NMR Center, Massachusetts General Hospital Harvard Medical School, Harvard MIT Division of Health Sciences and Technology, Charlestown 02129, USA
    Neuroimage 17:719-31. 2002
    ..This may reflect, at least in part, the superior contrast-to-noise ratio for oxyhemoglobin relative to deoxyhemoglobin (from optical measurements), rather than physiology related to BOLD signal interpretation...
  2. ncbi request reprint Quantitative small animal fluorescence tomography using an ultrafast gated image intensifier
    Sachin V Patwardhan
    Dept of Radiol, Washington Univ Sch of Med, St Louis, MO 63110, USA
    Conf Proc IEEE Eng Med Biol Soc 1:2675-8. 2006
    ..Here we present a time-resolved, charged coupled device (CCD) based system for quantitative small animal fluorescence tomography...
  3. ncbi request reprint Volumetric diffuse optical tomography of brain activity
    Joseph P Culver
    Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts 02129, USA
    Opt Lett 28:2061-3. 2003
    ..A combination of positional optode calibration and contrast-to-noise ratio weighting was found to improve imaging performance...
  4. ncbi request reprint Diffuse optical tomography of cerebral blood flow, oxygenation, and metabolism in rat during focal ischemia
    Joseph P Culver
    Department of Physics and Astronomy, Cerebrovascular Research Center, University of Pennsylvania, Philadelphia, Pennsylvania, U S A
    J Cereb Blood Flow Metab 23:911-24. 2003
    ....
  5. ncbi request reprint Three-dimensional diffuse optical tomography in the parallel plane transmission geometry: evaluation of a hybrid frequency domain/continuous wave clinical system for breast imaging
    J P Culver
    Department of Physics and Astronomy, University of Pennsylvania, Philadelphia, Pennsylvania 19104 6396, USA
    Med Phys 30:235-47. 2003
    ..In addition, we find that point spread function measurements provide a useful and comprehensive representation of system performance...
  6. ncbi request reprint Bulk optical properties of healthy female breast tissue
    T Durduran
    Department of Physics and Astronomy, University of Pennsylvania, Philadelphia 19104, USA
    Phys Med Biol 47:2847-61. 2002
    ..The new information on healthy breast tissue provides insight about the potential contrasts available for diffuse optical tomography of breast tumours...
  7. ncbi request reprint Near-field diffraction tomography with diffuse photon density waves
    X Li
    Department of Physics and Astronomy, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    Phys Rev E Stat Phys Plasmas Fluids Relat Interdiscip Topics 61:4295-309. 2000
    ..g., the slab medium). Limitations and potential improvements of the near-field diffraction tomography are also discussed...
  8. ncbi request reprint Can the cerebral metabolic rate of oxygen be estimated with near-infrared spectroscopy?
    D A Boas
    Athinoula A Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA
    Phys Med Biol 48:2405-18. 2003
    ..A more precise estimate of the flow-consumption ratio will require better estimates of the model parameters or flow information, as can be provided by combining NIRS with fMRI...
  9. ncbi request reprint In vivo cerebrovascular measurement combining diffuse near-infrared absorption and correlation spectroscopies
    C Cheung
    Department of Physics and Astronomy, University of Pennsylvania, Philadelphia 19104, USA
    Phys Med Biol 46:2053-65. 2001
    ....
  10. doi request reprint Quantitative diffuse optical tomography for small animals using an ultrafast gated image intensifier
    Sachin V Patwardhan
    Washington University School of Medicine, Department of Radiology, Mallinckrodt Institute of Radiology, St Louis, Missouri 63110, USA
    J Biomed Opt 13:011009. 2008
    ..Experiments with tissue simulating phantoms demonstrate the feasibility of reconstructing the absorption and scattering optical properties in a small animal imaging system...
  11. ncbi request reprint Singular-value analysis and optimization of experimental parameters in fluorescence molecular tomography
    Edward E Graves
    Center for Molecular Imaging Research, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, 149 13th Street, Room 5404, Charlestown, Massachusetts 02129, USA
    J Opt Soc Am A Opt Image Sci Vis 21:231-41. 2004
    ....
  12. ncbi request reprint Reconstructing chromosphere concentration images directly by continuous-wave diffuse optical tomography
    Ang Li
    Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts 02129, USA
    Opt Lett 29:256-8. 2004
    ..We demonstrate this improvement with simulations and a dynamic blood phantom experiment...
  13. pmc Hemodynamic evoked response of the sensorimotor cortex measured noninvasively with near-infrared optical imaging
    Maria Angela Franceschini
    NMR Center, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts 02129, USA
    Psychophysiology 40:548-60. 2003
    ..Our findings based on optical imaging are in agreement with results in the literature obtained with positron emission tomography and functional magnetic resonance imaging...
  14. ncbi request reprint Temporal comparison of functional brain imaging with diffuse optical tomography and fMRI during rat forepaw stimulation
    Andrew M Siegel
    Tufts University Bioengineering Center, Medford, MA 02155, USA
    Phys Med Biol 48:1391-403. 2003
    ....
  15. ncbi request reprint Optode positional calibration in diffuse optical tomography
    Jonathan J Stott
    Harvard Medical School Massachusetts Institute of Technology Athinoula A Martinos Center for Biomedical Imaging, Massachusetts General Hospital, 13th Street, Building 149, Charlestown, Massachusetts 02129, USA
    Appl Opt 42:3154-62. 2003
    ..We present a technique for simultaneously calibrating optode positions and reconstructing images that significantly improves image quality, as we demonstrate with simulations and phantom experiments...
  16. ncbi request reprint Evidence that cerebral blood volume can provide brain activation maps with better spatial resolution than deoxygenated hemoglobin
    Joseph P Culver
    Mallinckrodt Institute of Radiology, Washington University School of Medicine, 4525 Scott Avenue, St Louis, MO 63110, USA
    Neuroimage 27:947-59. 2005
    ..These results indicate that total hemoglobin and cerebral blood volume may have advantages as hemodynamic mapping contrasts, particularly for large amplitude, longer duration stimulus paradigms...
  17. pmc Retinotopic mapping of adult human visual cortex with high-density diffuse optical tomography
    Benjamin W Zeff
    Department of Radiology, Washington University School of Medicine, St Louis, MO 63110, USA
    Proc Natl Acad Sci U S A 104:12169-74. 2007
    ..These results demonstrate that high-density DOT is a practical and powerful tool for mapping function in the human cortex...
  18. ncbi request reprint A novel technique for light delivery through branched or bent anatomic structures
    Joseph S Friedberg
    Thomas Jefferson University Hospital, Philadelphia, PA, USA
    J Thorac Cardiovasc Surg 126:1963-7. 2003
    ..Such a technique could potentially expand the role of photodynamic therapy to treat tumors currently viewed as inaccessible to visible light...
  19. ncbi request reprint Diffuse optical measurement of hemoglobin and cerebral blood flow in rat brain during hypercapnia, hypoxia and cardiac arrest
    Joseph P Culver
    Department of Physics and Astronomy, University of Pennsylvania, Philadelphia, PA 19104, USA
    Adv Exp Med Biol 510:293-7. 2003
    ..The new instrument and concept may also be applicable to human studies especially in infants and neonates permitting noninvasive monitoring of cerebral hemodynamics and oxygen (see [4] and [2] for examples of NIR spectroscopy)...
  20. ncbi request reprint Robust inference of baseline optical properties of the human head with three-dimensional segmentation from magnetic resonance imaging
    Alex H Bamett
    Nuclear Magnetic Resonance Center, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts 02129, USA
    Appl Opt 42:3095-108. 2003
    ..We sample from the exact posterior and show robustness to numerical model error. This opens up the possibility of simultaneous DOT and MR for quantitative cortically constrained functional neuroimaging...