K R Cooke

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. ncbi Host reactive donor T cells are associated with lung injury after experimental allogeneic bone marrow transplantation
    K R Cooke
    Department of Pediatric Oncology, Dana Farber Cancer Institute the Department of Pathology, Brigham and Women s Hospital the Division of Pediatric Pulmonology, Children s Hospital, Boston, MA, 20115, USA
    Blood 92:2571-80. 1998
  2. ncbi The p55 TNF-alpha receptor plays a critical role in T cell alloreactivity
    G R Hill
    Department of Pediatric Oncology, Dana Farber Cancer Institute, Harvard Medical School, Boston, MA 02115, USA
    J Immunol 164:656-63. 2000
  3. ncbi Tumor necrosis factor- alpha production to lipopolysaccharide stimulation by donor cells predicts the severity of experimental acute graft-versus-host disease
    K R Cooke
    Department of Pediatric Oncology Dana Farber Cancer Institute, Children s Hospital, and Harvard Medical School, Boston, Massachusetts 02115, USA
    J Clin Invest 102:1882-91. 1998
  4. ncbi Differential roles of IL-1 and TNF-alpha on graft-versus-host disease and graft versus leukemia
    G R Hill
    Department of Pediatric Oncology, Dana Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts 02115, USA
    J Clin Invest 104:459-67. 1999

Detail Information

Publications4

  1. ncbi Host reactive donor T cells are associated with lung injury after experimental allogeneic bone marrow transplantation
    K R Cooke
    Department of Pediatric Oncology, Dana Farber Cancer Institute the Department of Pathology, Brigham and Women s Hospital the Division of Pediatric Pulmonology, Children s Hospital, Boston, MA, 20115, USA
    Blood 92:2571-80. 1998
    ..These findings may have important implications with regard to the evaluation and treatment of pulmonary dysfunction after allogeneic BMT even when clinical GVHD is absent...
  2. ncbi The p55 TNF-alpha receptor plays a critical role in T cell alloreactivity
    G R Hill
    Department of Pediatric Oncology, Dana Farber Cancer Institute, Harvard Medical School, Boston, MA 02115, USA
    J Immunol 164:656-63. 2000
    ....
  3. ncbi Tumor necrosis factor- alpha production to lipopolysaccharide stimulation by donor cells predicts the severity of experimental acute graft-versus-host disease
    K R Cooke
    Department of Pediatric Oncology Dana Farber Cancer Institute, Children s Hospital, and Harvard Medical School, Boston, Massachusetts 02115, USA
    J Clin Invest 102:1882-91. 1998
    ..These data suggest that the responsiveness of donor accessory cells to LPS may be an important risk factor for acute GVHD severity independent of T cell responses to host antigens...
  4. ncbi Differential roles of IL-1 and TNF-alpha on graft-versus-host disease and graft versus leukemia
    G R Hill
    Department of Pediatric Oncology, Dana Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts 02115, USA
    J Clin Invest 104:459-67. 1999
    ..These data highlight the importance of conditioning in GVHD pathophysiology, and demonstrate that TNF-alpha is critical to GVL mediated by donor T cells, whereas IL-1 is not...