K R Cooke
Affiliation: Harvard University
- Host reactive donor T cells are associated with lung injury after experimental allogeneic bone marrow transplantationK R Cooke
Department of Pediatric Oncology, Dana Farber Cancer Institute the Department of Pathology, Brigham and Women s Hospital the Division of Pediatric Pulmonology, Children s Hospital, Boston, MA, 20115, USA
Blood 92:2571-80. 1998..These findings may have important implications with regard to the evaluation and treatment of pulmonary dysfunction after allogeneic BMT even when clinical GVHD is absent...
- The p55 TNF-alpha receptor plays a critical role in T cell alloreactivityG R Hill
Department of Pediatric Oncology, Dana Farber Cancer Institute, Harvard Medical School, Boston, MA 02115, USA
J Immunol 164:656-63. 2000....
- Tumor necrosis factor- alpha production to lipopolysaccharide stimulation by donor cells predicts the severity of experimental acute graft-versus-host diseaseK R Cooke
Department of Pediatric Oncology Dana Farber Cancer Institute, Children s Hospital, and Harvard Medical School, Boston, Massachusetts 02115, USA
J Clin Invest 102:1882-91. 1998..These data suggest that the responsiveness of donor accessory cells to LPS may be an important risk factor for acute GVHD severity independent of T cell responses to host antigens...
- Differential roles of IL-1 and TNF-alpha on graft-versus-host disease and graft versus leukemiaG R Hill
Department of Pediatric Oncology, Dana Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts 02115, USA
J Clin Invest 104:459-67. 1999..These data highlight the importance of conditioning in GVHD pathophysiology, and demonstrate that TNF-alpha is critical to GVL mediated by donor T cells, whereas IL-1 is not...