- Immunohistochemical detection of mutant p53 protein in regional lymph nodes is associated with adverse outcome in stage II colorectal cancerG Clarke
Department of Gastroenterology, Mater Misericordiae Hospital, Dublin, Ireland
Eur J Histochem 43:311-6. 1999..Log Rank p = 0.028). Multivariate analysis also showed a significant relationship with mortality. (CPHT p = .03). We conclude that lymph node expression of Mp53P is associated with increased mortality in Duke's B CRC...
- Mortality association of enhanced CD44v6 expression is not mediated through occult lymphatic spread in stage II colorectal cancerG Clarke
Department of Gastroenterology, Mater Misericordiae Hospital Dublin, Ireland
J Gastroenterol Hepatol 15:1028-31. 2000..The aim of the present study was to determine if CD44v6 over-expression in Stage II CRC subjects was associated with the presence of lymph node micrometastases...
- Tumour-derived mutated K-ras codon 12 expression in regional lymph nodes of stage II colorectal cancer patients is not associated with increased risk of cancer-related deathG A Clarke
Division of Gastroenterology, Mater Misericordiae Hospital, University College Dublin, Eccles Street, Dublin 7, Ireland
Int J Colorectal Dis 16:108-11. 2001..Lymph node micrometastases detected by this technique thus show no relationship to mortality in stage II CRC. Further study of this technique is necessary before it can be used in the selection of patients for adjuvant chemotherapy...