Chee Yeun Chung

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. pmc Dynamic changes in presynaptic and axonal transport proteins combined with striatal neuroinflammation precede dopaminergic neuronal loss in a rat model of AAV alpha-synucleinopathy
    Chee Yeun Chung
    Neuroregeneration Laboratories, Harvard Medical School, McLean Hospital, Belmont, Massachusetts 02478, USA
    J Neurosci 29:3365-73. 2009
  2. pmc Functional enhancement and protection of dopaminergic terminals by RAB3B overexpression
    Chee Yeun Chung
    Neuroregeneration Laboratories, Harvard Medical School, McLean Hospital, 115 Mill Street, Belmont, MA 02478, USA
    Proc Natl Acad Sci U S A 106:22474-9. 2009
  3. pmc The Toll-like receptor-3 agonist polyinosinic:polycytidylic acid triggers nigrostriatal dopaminergic degeneration
    Michela Deleidi
    Center for Neuroregeneration Research, Harvard Medical School McLean Hospital, Belmont, Massachusetts, 02478, USA
    J Neurosci 30:16091-101. 2010
  4. pmc The transcription factor orthodenticle homeobox 2 influences axonal projections and vulnerability of midbrain dopaminergic neurons
    Chee Yeun Chung
    Neuroregeneration Laboratories, Harvard Medical School, McLean Hospital, 115 Mill Street, Belmont, MA 02478, USA
    Brain 133:2022-31. 2010
  5. pmc An endogenous serine/threonine protein phosphatase inhibitor, G-substrate, reduces vulnerability in models of Parkinson's disease
    Chee Yeun Chung
    Neuroregeneration Laboratories, Harvard Medical School, McLean Hospital, Belmont, Massachusetts 02478, USA
    J Neurosci 27:8314-23. 2007
  6. pmc High regulatability favors genetic selection in SLC18A2, a vesicular monoamine transporter essential for life
    Zhicheng Lin
    Department of Psychiatry, Harvard Medical School, Boston, Massachusetts, USA
    FASEB J 24:2191-200. 2010
  7. pmc Cell type-specific gene expression of midbrain dopaminergic neurons reveals molecules involved in their vulnerability and protection
    Chee Yeun Chung
    Neuroregeneration Laboratories, Harvard Medical School, McLean Hospital, Belmont, MA 02478, USA
    Hum Mol Genet 14:1709-25. 2005

Detail Information

Publications7

  1. pmc Dynamic changes in presynaptic and axonal transport proteins combined with striatal neuroinflammation precede dopaminergic neuronal loss in a rat model of AAV alpha-synucleinopathy
    Chee Yeun Chung
    Neuroregeneration Laboratories, Harvard Medical School, McLean Hospital, Belmont, Massachusetts 02478, USA
    J Neurosci 29:3365-73. 2009
    ..These findings can provide ideas for antecedent biomarkers and presymptomatic interventions in PD...
  2. pmc Functional enhancement and protection of dopaminergic terminals by RAB3B overexpression
    Chee Yeun Chung
    Neuroregeneration Laboratories, Harvard Medical School, McLean Hospital, 115 Mill Street, Belmont, MA 02478, USA
    Proc Natl Acad Sci U S A 106:22474-9. 2009
    ..These results suggest that RAB3B improves dopamine handling and storage capacity at presynaptic terminals, and confers protection to vulnerable DA neurons...
  3. pmc The Toll-like receptor-3 agonist polyinosinic:polycytidylic acid triggers nigrostriatal dopaminergic degeneration
    Michela Deleidi
    Center for Neuroregeneration Research, Harvard Medical School McLean Hospital, Belmont, Massachusetts, 02478, USA
    J Neurosci 30:16091-101. 2010
    ..New powerful neuroprotective therapies for PD might be considered by targeting critical inflammatory mechanisms, including cytokine-induced neurotoxicity...
  4. pmc The transcription factor orthodenticle homeobox 2 influences axonal projections and vulnerability of midbrain dopaminergic neurons
    Chee Yeun Chung
    Neuroregeneration Laboratories, Harvard Medical School, McLean Hospital, 115 Mill Street, Belmont, MA 02478, USA
    Brain 133:2022-31. 2010
    ..These results show that orthodenticle homeobox 2 is important for establishing subgroup phenotypes of post-mitotic midbrain dopaminergic neurons and may alter neuronal vulnerability...
  5. pmc An endogenous serine/threonine protein phosphatase inhibitor, G-substrate, reduces vulnerability in models of Parkinson's disease
    Chee Yeun Chung
    Neuroregeneration Laboratories, Harvard Medical School, McLean Hospital, Belmont, Massachusetts 02478, USA
    J Neurosci 27:8314-23. 2007
    ....
  6. pmc High regulatability favors genetic selection in SLC18A2, a vesicular monoamine transporter essential for life
    Zhicheng Lin
    Department of Psychiatry, Harvard Medical School, Boston, Massachusetts, USA
    FASEB J 24:2191-200. 2010
    ..These findings suggest that greater diversity of transcriptional regulations is the driving force for the haplotype selection in SLC18A2...
  7. pmc Cell type-specific gene expression of midbrain dopaminergic neurons reveals molecules involved in their vulnerability and protection
    Chee Yeun Chung
    Neuroregeneration Laboratories, Harvard Medical School, McLean Hospital, Belmont, MA 02478, USA
    Hum Mol Genet 14:1709-25. 2005
    ..These results indicate that certain differentially expressed molecules in A9 and A10 DA neurons may play key roles in their relative vulnerability to toxins and PD...