Nicholas A Christakis

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. pmc Social networks and cooperation in hunter-gatherers
    Coren L Apicella
    Institute for Quantitative Social Science, Harvard University, Cambridge, Massachusetts 02138, USA
    Nature 481:497-501. 2012
  2. pmc Social contagion theory: examining dynamic social networks and human behavior
    Nicholas A Christakis
    Department of Medicine, Harvard Medical School, Boston, MA 02115, U S A
    Stat Med 32:556-77. 2013
  3. ncbi request reprint The spread of obesity in a large social network over 32 years
    Nicholas A Christakis
    Department of Health Care Policy, Harvard Medical School, Boston, MA 02115, USA
    N Engl J Med 357:370-9. 2007
  4. pmc Don't just blame the system
    Nicholas A Christakis
    BMJ 336:747. 2008
  5. pmc The collective dynamics of smoking in a large social network
    Nicholas A Christakis
    Department of Health Care Policy, Harvard Medical School, Boston, MA 02115, USA
    N Engl J Med 358:2249-58. 2008
  6. ncbi request reprint Mortality after the hospitalization of a spouse
    Nicholas A Christakis
    Department of Health Care Policy, Harvard Medical School, and the Palliative Care Service, Department of Medicine, Massachusetts General Hospital, Boston, MA 02115, USA
    N Engl J Med 354:719-30. 2006
  7. pmc The spread of alcohol consumption behavior in a large social network
    J Niels Rosenquist
    Massachusetts General Hospital, Harvard Medical School, and Boston University School of Medicine, 180 A Longwood Avenue, Boston, MA 02115, USA
    Ann Intern Med 152:426-33, W141. 2010
  8. pmc When networks can teach us about drug use
    Nicholas A Christakis
    Harvard Medical School, Cambridge, Massachusetts, USA
    BMJ 336:420. 2008
  9. pmc Social network sensors for early detection of contagious outbreaks
    Nicholas A Christakis
    Faculty of Arts and Sciences, Harvard University, Boston, Massachusetts, United States of America
    PLoS ONE 5:e12948. 2010
  10. ncbi request reprint The health impact of health care on families: a matched cohort study of hospice use by decedents and mortality outcomes in surviving, widowed spouses
    Nicholas A Christakis
    Department of Health Care Policy, Harvard Medical School, 180 Longwood Avenue, Boston, MA 02115, USA
    Soc Sci Med 57:465-75. 2003

Detail Information

Publications61

  1. pmc Social networks and cooperation in hunter-gatherers
    Coren L Apicella
    Institute for Quantitative Social Science, Harvard University, Cambridge, Massachusetts 02138, USA
    Nature 481:497-501. 2012
    ..Also, early humans may have formed ties with both kin and non-kin, based in part on their tendency to cooperate. Social networks may thus have contributed to the emergence of cooperation...
  2. pmc Social contagion theory: examining dynamic social networks and human behavior
    Nicholas A Christakis
    Department of Medicine, Harvard Medical School, Boston, MA 02115, U S A
    Stat Med 32:556-77. 2013
    ....
  3. ncbi request reprint The spread of obesity in a large social network over 32 years
    Nicholas A Christakis
    Department of Health Care Policy, Harvard Medical School, Boston, MA 02115, USA
    N Engl J Med 357:370-9. 2007
    ..The prevalence of obesity has increased substantially over the past 30 years. We performed a quantitative analysis of the nature and extent of the person-to-person spread of obesity as a possible factor contributing to the obesity epidemic...
  4. pmc Don't just blame the system
    Nicholas A Christakis
    BMJ 336:747. 2008
  5. pmc The collective dynamics of smoking in a large social network
    Nicholas A Christakis
    Department of Health Care Policy, Harvard Medical School, Boston, MA 02115, USA
    N Engl J Med 358:2249-58. 2008
    ..We examined the extent of the person-to-person spread of smoking behavior and the extent to which groups of widely connected people quit together...
  6. ncbi request reprint Mortality after the hospitalization of a spouse
    Nicholas A Christakis
    Department of Health Care Policy, Harvard Medical School, and the Palliative Care Service, Department of Medicine, Massachusetts General Hospital, Boston, MA 02115, USA
    N Engl J Med 354:719-30. 2006
    ..The illness of a spouse can affect the health of a caregiving partner. We examined the association between the hospitalization of a spouse and a partner's risk of death among elderly people...
  7. pmc The spread of alcohol consumption behavior in a large social network
    J Niels Rosenquist
    Massachusetts General Hospital, Harvard Medical School, and Boston University School of Medicine, 180 A Longwood Avenue, Boston, MA 02115, USA
    Ann Intern Med 152:426-33, W141. 2010
    ..Alcohol consumption has important health-related consequences and numerous biological and social determinants...
  8. pmc When networks can teach us about drug use
    Nicholas A Christakis
    Harvard Medical School, Cambridge, Massachusetts, USA
    BMJ 336:420. 2008
  9. pmc Social network sensors for early detection of contagious outbreaks
    Nicholas A Christakis
    Faculty of Arts and Sciences, Harvard University, Boston, Massachusetts, United States of America
    PLoS ONE 5:e12948. 2010
    ..The amount of lead time will depend on features of the outbreak and the network at hand. The method could in principle be generalized to other biological, psychological, informational, or behavioral contagions that spread in networks...
  10. ncbi request reprint The health impact of health care on families: a matched cohort study of hospice use by decedents and mortality outcomes in surviving, widowed spouses
    Nicholas A Christakis
    Department of Health Care Policy, Harvard Medical School, 180 Longwood Avenue, Boston, MA 02115, USA
    Soc Sci Med 57:465-75. 2003
    ..Health care may have positive, group-level health "externalities": it may affect the health not only of patients but also of patients' family members...
  11. ncbi request reprint Care after the onset of serious illness: a novel claims-based dataset exploiting substantial cross-set linkages to study end-of-life care
    Nicholas A Christakis
    Department of Health Care Policy, Harvard Medical School, Boston, Massachusetts 02115, USA
    J Palliat Med 5:515-29. 2002
    ..Detailed health information about cohort members' spouses was also collected. We conclude by highlighting the types of analyses that can be conducted in this data set...
  12. ncbi request reprint Measuring clinically significant chemotherapy-related toxicities using Medicare claims from Cancer and Leukemia Group B (CALGB) trial participants
    Elizabeth B Lamont
    Massachusetts General Hospital, Boston, Massachusetts, USA
    Med Care 46:303-8. 2008
    ..Because the elderly are underrepresented on clinical trials, physicians have few sources of information to estimate the risks (ie, toxicities) and benefits of chemotherapy administration to the elderly...
  13. pmc Using administrative data to identify naturally occurring networks of physicians
    Bruce E Landon
    Department of Health Care Policy, Harvard Medical School, Boston, MA 02115, USA
    Med Care 51:715-21. 2013
    ..Physicians naturally form networks. Networks could form a rational basis for Accountable Care Organizations (ACOs) for defined populations of Medicare beneficiaries...
  14. ncbi request reprint Measuring disease-free survival and cancer relapse using Medicare claims from CALGB breast cancer trial participants (companion to 9344)
    Elizabeth B Lamont
    Massachusetts General Hospital Cancer Center and Institute for Technology Assessment, Massachusetts General Hospital, Boston, MA, USA
    J Natl Cancer Inst 98:1335-8. 2006
    ....
  15. pmc Variation in patient-sharing networks of physicians across the United States
    Bruce E Landon
    Department of Health Care Policy, School of Medicine, Harvard University, Cambridge, Massachusetts, USA
    JAMA 308:265-73. 2012
    ..Physicians are embedded in informal networks that result from their sharing of patients, information, and behaviors...
  16. pmc Mapping physician networks with self-reported and administrative data
    Michael L Barnett
    Department of Health Care Policy, Harvard Medical School, Boston, MA 02215, USA
    Health Serv Res 46:1592-609. 2011
    ..To assess whether connections between physicians based on shared patients in administrative data correspond with professional relationships between physicians...
  17. pmc Reasons for choice of referral physician among primary care and specialist physicians
    Michael L Barnett
    Department of Health Care Policy, Harvard Medical School, 180 Longwood Avenue, Boston, MA 02215, USA
    J Gen Intern Med 27:506-12. 2012
    ..For a given clinical problem, referring physicians usually have a choice of several physicians to whom they can refer. Once the decision to refer is made, the choice of individual physician may have important downstream effects...
  18. pmc Effects of proximate foreclosed properties on individuals' weight gain in Massachusetts, 1987-2008
    Mariana Arcaya
    Department of Society, Human Development, and Health, Harvard School of Public Health, Boston, MA, USA
    Am J Public Health 103:e50-6. 2013
    ..We assessed the extent to which living near foreclosed properties is associated with individuals' subsequent weight gain...
  19. pmc Physician patient-sharing networks and the cost and intensity of care in US hospitals
    Michael L Barnett
    Department of Health Care Policy, Harvard Medical School, Boston, MA 02215, USA
    Med Care 50:152-60. 2012
    ..There is substantial variation in the cost and intensity of care delivered by US hospitals. We assessed how the structure of patient-sharing networks of physicians affiliated with hospitals might contribute to this variation...
  20. pmc Dynamic social networks promote cooperation in experiments with humans
    David G Rand
    Program for Evolutionary Dynamics, Department of Psychology, Institute for Quantitative Social Science, Harvard University, Cambridge, MA 02138
    Proc Natl Acad Sci U S A 108:19193-8. 2011
    ..Our experiments confirm the predictions of a set of evolutionary game theoretic models and demonstrate the important role that dynamic social networks can play in supporting large-scale human cooperation...
  21. pmc Population trends and variation in body mass index from 1971 to 2008 in the Framingham Heart Study Offspring Cohort
    Jason P Block
    Obesity Prevention Program, Department of Population Medicine, Harvard Medical School Harvard Pilgrim Health Care Institute, Boston, Massachusetts, United States of America
    PLoS ONE 8:e63217. 2013
    ..We examined body mass index (BMI) across place and time to determine the pattern of BMI mean and standard deviation trajectories...
  22. pmc Parental influence on substance use in adolescent social networks
    Holly B Shakya
    Department of Medicine, School of Medicine, University of California, San Diego, USA
    Arch Pediatr Adolesc Med 166:1132-9. 2012
    ..To evaluate the relationship between the parenting style of an adolescent's peers' parents and an adolescent's substance use...
  23. pmc Evolution of in-group favoritism
    Feng Fu
    Program for Evolutionary Dynamics, Harvard University, Cambridge, Massachusetts 02138, USA
    Sci Rep 2:460. 2012
    ..Our framework also allows us to implement different games for these two types of interactions. We prove general results and derive specific conditions for the evolution of cooperation based on in-group favoritism...
  24. pmc Minimal social network effects evident in cancer screening behavior
    Nancy L Keating
    Division of General Internal Medicine, Department of Medicine, Brigham and Women s Hospital, Boston, Massachusetts, USA
    Cancer 117:3045-52. 2011
    ..Social networks may influence screening behaviors. We assessed whether screening for breast, prostate, or colorectal cancer is influenced by the actual screening behaviors of siblings, friends, spouses, and coworkers...
  25. ncbi request reprint Marriage, widowhood, and health-care use
    Theodore J Iwashyna
    Department of Medicine, Hospital of the University of Pennsylvania, Pennsylvania, PA, USA
    Soc Sci Med 57:2137-47. 2003
    ..We suggest that these patterns are most consistent with spouses exerting their benefits by functioning as higher-order decision-makers than as home health assistants...
  26. pmc The lack of effect of market structure on hospice use
    Theodore J Iwashyna
    Department of Medicine, Hospital of the University of Pennsylvania, USA
    Health Serv Res 37:1531-51. 2002
    ..To describe the relative importance of health care market structure and county-level demographics in determining rates of hospice use...
  27. ncbi request reprint Effects of proximate foreclosed properties on individuals' systolic blood pressure in Massachusetts, 1987 to 2008
    Mariana Arcaya
    From the Department of Social and Behavioral Sciences, Harvard School of Public Health, Cambridge, MA M A, I K, S V S Department of Epidemiology and Biostatistics, University of California San Francisco School of Medicine M M G Federal Reserve Bank of Boston, Boston, MA P C and Yale Institute for Network Science, Yale University, New Haven, CT N A C
    Circulation 129:2262-8. 2014
    ..We assessed the extent to which living near foreclosed properties is associated with subsequent systolic blood pressure (SBP) measurements...
  28. pmc Egocentric social network structure, health, and pro-social behaviors in a national panel study of Americans
    A James O'Malley
    Department of Health Care Policy, Harvard Medical School, Boston, Massachusetts, United States of America
    PLoS ONE 7:e36250. 2012
    ....
  29. ncbi request reprint Criterion validity of Medicare chemotherapy claims in Cancer and Leukemia Group B breast and lung cancer trial participants
    Elizabeth B Lamont
    Department of Medicine and Institute for Technology Assessment, Massachusetts General Hospital, Boston, MA 02114, USA
    J Natl Cancer Inst 97:1080-3. 2005
    ..Administrative Medicare claims data appear to be a valid source of information for chemotherapy administered to elderly Medicare beneficiaries with cancer...
  30. pmc Proximity to food establishments and body mass index in the Framingham Heart Study offspring cohort over 30 years
    Jason P Block
    Department of Population Medicine, Harvard Pilgrim Health Care Institute, Harvard Medical School, 133 Brookline Avenue, Boston, MA 02215, USA
    Am J Epidemiol 174:1108-14. 2011
    ....
  31. ncbi request reprint Complexities in prognostication in advanced cancer: "to help them live their lives the way they want to"
    Elizabeth B Lamont
    Section of General Internal Medicine, Department of Medicine, and the Cancer Research Center, University of Chicago, Chicago, IL, USA
    JAMA 290:98-104. 2003
    ..Using the vignette of a real patient with advanced cancer who far outlived her physician's prognostic estimate, we discuss clinical issues related to the science of prognosis in advanced cancer and the art of its disclosure...
  32. pmc A dynamic network approach for the study of human phenotypes
    César A Hidalgo
    Center for International Development and Harvard Kennedy School, Harvard University, Cambridge, Massachusetts, United States of America
    PLoS Comput Biol 5:e1000353. 2009
    ..The dataset introduced here, released concurrently with this publication, represents the largest relational phenotypic resource publicly available to the research community...
  33. pmc Emotions as infectious diseases in a large social network: the SISa model
    Alison L Hill
    Program for Evolutionary Dynamics, Berkman Center for Internet and Society, Department of Mathematics, Harvard University, Cambridge, MA 02138, USA
    Proc Biol Sci 277:3827-35. 2010
    ..Our model provides a theoretical framework for studying the interpersonal spread of any state that may also arise spontaneously, such as emotions, behaviours, health states, ideas or diseases with reservoirs...
  34. pmc Medicine may change our genes
    Nicholas A Christakis
    Harvard Medical School, USA
    BMJ 336:1101. 2008
  35. pmc Geographic constraints on social network groups
    Jukka Pekka Onnela
    Department of Health Care Policy, Harvard Medical School, Boston, Massachusetts, United States of America
    PLoS ONE 6:e16939. 2011
    ..Also, we find no correlation between the topological positions and geographic positions of individuals within network communities. These results suggest that spreading processes face distinct structural and spatial constraints...
  36. pmc The evolution of homophily
    Feng Fu
    Department of Health Care Policy, Harvard Medical School, Boston, MA 02115, USA
    Sci Rep 2:845. 2012
    ..The results show that homophily tends to evolve under a wide variety of conditions, helping to explain its ubiquity in nature...
  37. pmc Viral perturbations of host networks reflect disease etiology
    Natali Gulbahce
    Center for Complex Networks Research CCNR and Department of Physics, Northeastern University, Boston, Massachusetts, United States of America
    PLoS Comput Biol 8:e1002531. 2012
    ..The topological proximity found between cellular targets of viral proteins and disease genes was exploited to uncover a novel pathway linking HPV to Fanconi anemia...
  38. pmc Spreading paths in partially observed social networks
    Jukka Pekka Onnela
    Department of Biostatistics, Harvard School of Public Health, Boston, Massachusetts 02115, USA
    Phys Rev E Stat Nonlin Soft Matter Phys 85:036106. 2012
    ..We find that the partially observed shortest path does not necessarily give an inflated estimate of the length of the process path; in fact, partial observation may, counterintuitively, make the path seem shorter than it actually is...
  39. pmc Longitudinal analysis of large social networks: estimating the effect of health traits on changes in friendship ties
    A James O'Malley
    Department of Health Care Policy, Harvard Medical School, 180 Longwood Avenue, Boston, MA 02115, USA
    Stat Med 30:950-64. 2011
    ..We also validated previously known findings regarding homophily on age and gender, and found evidence that homophily also depends upon geographic separation...
  40. ncbi request reprint Disease-specific patterns of hospice and related healthcare use in an incidence cohort of seriously ill elderly patients
    Theodore J Iwashyna
    Department of Medicine, Hospital of the University at Pennsylvania, Philadelphia, Pennsylvania, USA
    J Palliat Med 5:531-8. 2002
    ..7%. Among decedents with cancer diagnoses, rates vary from 15.2% to 35.2%. For the cohort overall, 14.2% of male decedents and 12.4% of female decedents used hospice. Patterns of end-of-life care vary substantially according to diagnosis...
  41. pmc Infectious disease modeling of social contagion in networks
    Alison L Hill
    Program for Evolutionary Dynamics, Harvard University, Cambridge, Massachusetts, United States of America
    PLoS Comput Biol 6:e1000968. 2010
    ..It provides a theoretical framework for studying the interpersonal spread of any state that may also arise spontaneously, such as emotions, behaviors, health states, ideas or diseases with reservoirs...
  42. doi request reprint Too quietly into the night
    Nicholas A Christakis
    Harvard Medical School, USA
    BMJ 337:a696. 2008
  43. pmc Association between widowhood and risk of diagnosis with a sexually transmitted infection in older adults
    Kirsten P Smith
    Department of Health Care Policy, Harvard Medical School, 180 Longwood Avenue, Boston, MA 02115, USA
    Am J Public Health 99:2055-62. 2009
    ....
  44. ncbi request reprint On the prospects for a blame-free medical culture
    Molly E Collins
    Department of Medicine, Hospital of the University of Pennsylvania, Philadelphia, PA, United States of America
    Soc Sci Med 69:1287-90. 2009
    ..Given that physicians' ideology of self-blame is ingrained, accompanied by benefits, and limits a systems perspective on error, it may subvert attempts to establish a blame-free culture...
  45. pmc Quality versus quantity of social ties in experimental cooperative networks
    Hirokazu Shirado
    1 Corporate R and D, Sony Corporation, Shinagawa, Tokyo 141 0001, Japan 2 Department of Health Care Policy, Harvard Medical School, Boston, Massachusetts 02115, USA
    Nat Commun 4:2814. 2013
    ..Optimal levels of cooperation are achieved at intermediate levels of change in social ties. ..
  46. pmc The impact of cellular networks on disease comorbidity
    Juyong Park
    Department of Physics, Biology, and Computer Science, Center for Complex Network Research, Northeastern University, Boston, MA 02115, USA
    Mol Syst Biol 5:262. 2009
    ..Our results indicate that such a combination of population-level data and cellular network information could help build novel hypotheses about disease mechanisms...
  47. pmc Racial, ethnic, and affluence differences in elderly patients' use of teaching hospitals
    Theodore J Iwashyna
    Department of Medicine, University of Pennsylvania Medical Center, Philadelphia, USA
    J Gen Intern Med 17:696-703. 2002
    ..To understand the role of race, ethnicity, and affluence in elderly patients' use of teaching hospitals when they have that option...
  48. ncbi request reprint Favorable cardiac risk among elderly breast carcinoma survivors
    Elizabeth B Lamont
    Section of General Internal Medicine, Department of Medicine, The University of Chicago, Chicago, Illinois 60637, USA
    Cancer 98:2-10. 2003
    ..First, estrogens may be etiologic in the development of breast carcinoma and protective of CHD. Second, a common therapy for breast carcinoma (tamoxifen) may be associated with cardiac protection...
  49. pmc Health care in a web
    Nicholas A Christakis
    Harvard Medical School, USA
    BMJ 336:1468. 2008
  50. doi request reprint Valuing the well connected
    Nicholas A Christakis
    Harvard Medical School, USA
    BMJ 337:a1675. 2008
  51. pmc Neighborhood effects on posthospitalization mortality: a population-based cohort study of the elderly in Chicago
    Ming Wen
    Department of Sociology, University of Utah, Salt Lake City, UT 84112, USA
    Health Serv Res 40:1108-27. 2005
    ..Place of residence is associated with health outcomes...
  52. ncbi request reprint Identifying, recruiting, and retaining seriously-ill patients and their caregivers in longitudinal research
    Karen E Steinhauser
    Center for Health Services Research in Primary Care, Durham VA Medical Center, Duke University, NC 27705, USA
    Palliat Med 20:745-54. 2006
    ..The palliative care literature is replete with descriptions of studies unable to meet enrollment goals, and that as a result, do not have adequate power to test hypotheses or draw conclusions...
  53. ncbi request reprint The emotional toll of spousal morbidity and mortality
    Kara Zivin
    Veterans Affairs, Health Services Research and Development, Serious Mental Illness Treatment Research and Evaluation Center, Ann Arbor, MI 48113 0170, USA
    Am J Geriatr Psychiatry 15:772-9. 2007
    ....
  54. pmc The effect of widowhood on mortality by the causes of death of both spouses
    Felix Elwert
    Department of Sociology, University of Wisconsin, Madison, WI 53706, USA
    Am J Public Health 98:2092-8. 2008
    ..We investigated the effect of spousal bereavement on mortality to document cause-specific bereavement effects by the causes of death of both the predecedent spouse and the bereaved partner...
  55. ncbi request reprint Construct validity of medicare chemotherapy claims: the case of 5FU
    Elizabeth B Lamont
    Section of Hematology Oncology, University of Chicago, Illinois 60637, USA
    Med Care 40:201-11. 2002
    ..The elderly are under represented in clinical trials of cancer therapy and the elderly who are enrolled may be unrepresentative...
  56. ncbi request reprint "Are you at peace?": one item to probe spiritual concerns at the end of life
    Karen E Steinhauser
    Centers for Palliative Care, Veterans Affairs Medical Center, and Department of Medicine, Division of Geriatrics, School of Nursing, Center for the Study of Aging and Human Development, Duke University, Durham, NC 27705, USA
    Arch Intern Med 166:101-5. 2006
    ..A practical, evidence-based approach to discussing spiritual concerns in a scope suitable to a physician-patient relationship may improve the quality of the clinical encounter...
  57. ncbi request reprint Geographic variation in hospice use in the United States in 2002
    Stephen R Connor
    National Hospice and Palliative Care Organization, Alexandria, Virginia 22314, USA
    J Pain Symptom Manage 34:277-85. 2007
    ..State-specific usage rates ranged from 8% in Alaska to 49% in Arizona. Our findings highlight opportunities for the hospice industry to provide more care, opportunities defined by diagnostic and geographic axes...
  58. ncbi request reprint Income inequality and weight status in US metropolitan areas
    Virginia W Chang
    Center for Health Equity Research and Promotion, Philadelphia VAMC, USA
    Soc Sci Med 61:83-96. 2005
    ..Although our findings are suggestive of a contextual effect of metropolitan area income inequality, we do not find an increased risk for unhealthy weight outcomes, adding to recent debates surrounding this topic...
  59. ncbi request reprint Initial assessment of a new instrument to measure quality of life at the end of life
    Karen E Steinhauser
    Program on the Medical Encounter and Palliative Care, Center for Health Services Research in Primary Care, Durham VA Medical Center, Durham, North Carolina 27705, USA
    J Palliat Med 5:829-41. 2002
    ..We conducted this study to pilot a new multidimensional instrument to assess the quality of life at the end of life...
  60. pmc Social networks and collateral health effects
    Nicholas A Christakis
    BMJ 329:184-5. 2004
  61. ncbi request reprint Prospective effect of community distress and subcultural orientation on mortality following life-threatening diseases in later life
    Ming Wen
    Department of Sociology, University of Utah, Salt Lake City, UT 84112 0250, USA
    Sociol Health Illn 28:558-82. 2006
    ..The social, economic, physical and cultural environment in which people live appears to exert a significant impact on whether older people facing life-threatening illness live or die...