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..Individuals with a family history of colorectal cancer may be more susceptible to adverse effects of alcohol consumption...

..The association between lutein/zeaxanthin intake and age-related macular degeneration (AMD) risk may differ by smoking status, vitamin C and E intakes, and body fatness...

..Several other occupational and lifestyle factors may also affect the risk of RCC. Genetic variations may be an important factor in the differing incidence among populations...

..To examine the intake of antioxidant vitamins and carotenoids as well as fruits and vegetables in relation to the development of age-related maculopathy (ARM)...

..In conclusion, we found no evidence that higher intakes of nutrients involved in one-carbon metabolism reduce risk of breast cancer among premenopausal women...

..Studies in animals have suggested that calcium may reduce the risk of colorectal cancer. However, results from epidemiologic studies of intake of calcium or dairy foods and colorectal cancer risk have been inconclusive...

..No epidemiologic study has examined the association of intake of these nutrients and colorectal adenoma risk...

..Although breast tumors differ clinically and biologically by hormone receptor status, few epidemiologic studies of diet have made this distinction...

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..No prospective study among post-menopausal women has examined choline and betaine intakes in relation to breast cancer risk...

..However, findings related to specific alcoholic beverages or different anatomic sites in the large bowel have been inconsistent...

..Epidemiologic data suggest that analgesic use increases the risk of renal cell cancer (RCC), but few prospective studies have been published. We investigated the association between analgesic use and RCC in 2 large prospective studies...

..The relation between intakes of total fat and specific types of fat and age-related macular degeneration (AMD) remains unclear...

..Zinc is found in high concentrations in the retina and is hypothesized to reduce the risk of age-related macular degeneration (AMD). Any long-term benefit associated with dietary zinc intake has not been evaluated...

..To examine the relationship of obesity, measured as BMI, and weight change to incidence of coronary heart disease (CHD) among women with diabetes...

..The goal of this study was to examine the impact of diabetes and prior myocardial infarction (MI) on mortality in men...

..The physiologic relevance of a variation in dietary choline and betaine in the general population and the validity of intake assessed by food-frequency questionnaire (FFQ) have not been evaluated...

..We conducted a prospective analysis of the relation between dietary fat intake and breast cancer risk among premenopausal women enrolled in the Nurses' Health Study II...

..We found no evidence that higher intakes of vitamins C and E, and folate in early adult life reduce risk of breast cancer. However, intake of vitamin A may be related to a reduced risk of breast cancer among smokers...

..Our data do not support a strong association between fiber intake and breast cancer risk...

..04). Age, family history of melanoma, and hair color did not statistically differ by anatomic site of the cancer. These data support divergent etiologic pathways of melanoma development by anatomic sites...

..To describe the relationship between alcohol consumption and the incidence of age-related macular degeneration (AMD)...

..89, 95% CI: 0.81, 0.98; p(trend) = 0.01). The authors' findings suggest that higher intake of long-chain omega-3 fatty acid (eicosapentaenoic acid and docosahexaenoic acid) and consumption of fish may modestly reduce the risk of cataract...

..Statistical power to examine associations by colon site has been limited in previous studies...

..We examined the association between adolescent fiber intake and proliferative BBD, a marker of increased breast cancer risk, in the Nurses' Health Study II...

..Our data do not support the hypothesis that choline and betaine intake is inversely associated with colorectal cancer risk...

..They found no evidence that acrylamide intake, within the range of US diets, is associated with increased risk of premenopausal breast cancer...

..We aimed to assess the relationship between red meat intake during adolescence and premenopausal breast cancer...

..No clear associations were observed for PMH use or duration, time since last PMH use, oral contraceptive use or duration, age at menarche, age at menopause, or history of hysterectomy or oophorectomy...

..13 (0.95-1.34) for lycopene. In conclusion, increasing fruit and vegetable consumption is associated with decreasing risk of renal cell cancer; carotenoids present in fruit and vegetables may partly contribute to this protection...

..Mutagenic compounds produced when meats are cooked at high temperatures have been hypothesized to increase risk of breast cancer...

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..To investigate whether estrogen exposures are associated with lower risks of age-related macular degeneration (AMD)...

..05). Vegetable fat, vitamin E, and fiber intakes during adolescence were inversely associated with risk of proliferative BBD in this population. Confirmation of these associations may suggest a means for prevention of breast cancer...

..To investigate the association between smoking and invasive breast cancers characterized by their estrogen receptor status in a large prospective study of mainly premenopausal women...

..With a prospective design and repeated measures of variables, we sought to analyse the temporal relation between marital transition and change in health behaviours...

..76 (0.57, 1.00; p-value for test of trend=0.03). While we found no overall association between intake of flavonols and risk of breast cancer, there was an inverse association with intake of beans or lentils that merits further evaluation...

..In addition, high consumption of cereal fiber was associated with lower risk of total and hemorrhagic stroke...

..The results generally did not differ across studies or by sex, smoking habits and lung cancer cell type. In conclusion, these data do not support the hypothesis that intakes of vitamins A, C and E and folate reduce lung cancer risk...

..We examined data from the Nurses Health Study II to evaluate the association between major dietary patterns and the risk of breast cancer among pre-menopausal women...

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..Most of the methods used in the Pooling Project may be adapted for examining associations with dietary and nondietary factors in pooled analyses of case-control studies or case-control and cohort studies combined...

..An inverse association between alcohol intake and risk of renal cell cancer has been suggested in a few prospective studies, but each of these studies included a small number of cases...

..Instead, greater consumption of coffee and tea may be associated with a lower risk of renal cell cancer. (c) 2007 Wiley-Liss, Inc...

..We examined whether overall obesity (body mass index (BMI)) and abdominal obesity (waist circumference (WC)) are independently associated with hypertriglyceridemia among the Korean population...

..Nutritional therapy is a cornerstone of diabetes management, but no epidemiologic studies have investigated the relation between specific dietary fatty acids and cholesterol and cardiovascular disease (CVD) risk among diabetic patients...

..Type 2 diabetes is associated with increased risks of several types of cancer; however, its relationship to renal cell cancer remains unclear...

..The results from the proposed grant will enhance understanding of the role of choline intake in humans and lay the groundwork for future studies on choline intake and overall methyl-group-deficient diet and cancer. ..

..The findings from the proposed grant will complement our previous work on choline and betaine and enhance our understanding of the role of these nutrients in carcinogenesis in human as this area of research is largely unexplored. ..

..Creation of 'dietary methyl score' will present the optimum balance of multiple dietary factors affecting one-carbon metabolism to reduce cancer risk and help produce practical dietary guidelines for cancer prevention. ..

..Creation of 'dietary methyl score'will present the optimum balance of multiple dietary factors affecting one-carbon metabolism to reduce cancer risk and help produce practical dietary guidelines for cancer prevention. ..