Peter Chien

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. ncbi request reprint Emerging principles of conformation-based prion inheritance
    Peter Chien
    Graduate Group in Biophysics, Howard Hughes Medical Institute, Department of Cellular and Molecular Pharmacology, University of California, San Francisco, California 94107 2240, USA
    Annu Rev Biochem 73:617-56. 2004
  2. ncbi request reprint Mechanism of cross-species prion transmission: an infectious conformation compatible with two highly divergent yeast prion proteins
    Motomasa Tanaka
    Howard Hughes Medical Institute, Department of Cellular and Molecular Pharmacology, University of California, San Francisco, California 94143, USA
    Cell 121:49-62. 2005
  3. ncbi request reprint Conformational variations in an infectious protein determine prion strain differences
    Motomasa Tanaka
    Howard Hughes Medical Institute, Department of Cellular and Molecular Pharmacology, University of California San Francisco, San Francisco, California 94143, USA
    Nature 428:323-8. 2004
  4. ncbi request reprint Generation of prion transmission barriers by mutational control of amyloid conformations
    Peter Chien
    Graduate Group in Biophysics, University of California San Francisco, San Francisco, California 94143 2240, USA
    Nature 424:948-51. 2003
  5. ncbi request reprint Structure and substrate specificity of an SspB ortholog: design implications for AAA+ adaptors
    Peter Chien
    Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA
    Structure 15:1296-305. 2007

Detail Information

Publications5

  1. ncbi request reprint Emerging principles of conformation-based prion inheritance
    Peter Chien
    Graduate Group in Biophysics, Howard Hughes Medical Institute, Department of Cellular and Molecular Pharmacology, University of California, San Francisco, California 94107 2240, USA
    Annu Rev Biochem 73:617-56. 2004
    ..This model helps explain many common and otherwise puzzling features of prion inheritance as well as aspects of noninfectious diseases involving toxic misfolded proteins...
  2. ncbi request reprint Mechanism of cross-species prion transmission: an infectious conformation compatible with two highly divergent yeast prion proteins
    Motomasa Tanaka
    Howard Hughes Medical Institute, Department of Cellular and Molecular Pharmacology, University of California, San Francisco, California 94143, USA
    Cell 121:49-62. 2005
    ....
  3. ncbi request reprint Conformational variations in an infectious protein determine prion strain differences
    Motomasa Tanaka
    Howard Hughes Medical Institute, Department of Cellular and Molecular Pharmacology, University of California San Francisco, San Francisco, California 94143, USA
    Nature 428:323-8. 2004
    ....
  4. ncbi request reprint Generation of prion transmission barriers by mutational control of amyloid conformations
    Peter Chien
    Graduate Group in Biophysics, University of California San Francisco, San Francisco, California 94143 2240, USA
    Nature 424:948-51. 2003
    ....
  5. ncbi request reprint Structure and substrate specificity of an SspB ortholog: design implications for AAA+ adaptors
    Peter Chien
    Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA
    Structure 15:1296-305. 2007
    ..These results highlight general features of adaptor-mediated substrate recognition and shed light on design principles that underlie adaptor function...