L B Chibnik

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. pmc Comparison of threshold cutpoints and continuous measures of anti-cyclic citrullinated peptide antibodies in predicting future rheumatoid arthritis
    Lori B Chibnik
    Division of Rheumatology, Immunology, and Allergy, Brigham and Women s Hospital, Harvard Medical School, 75 Francis St, Boston, MA 02115, USA
    J Rheumatol 36:706-11. 2009
  2. pmc Identification and validation of lupus nephritis cases using administrative data
    L B Chibnik
    Division of Rheumatology, Immunology and Allergy, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
    Lupus 19:741-3. 2010
  3. ncbi request reprint Dietary caffeine intake does not affect methotrexate efficacy in patients with rheumatoid arthritis
    Elizabeth Benito-Garcia
    Division of Rheumatology, Immunology and Allergy, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
    J Rheumatol 33:1275-81. 2006
  4. pmc The relationship between disease activity, sleep, psychiatric distress and pain sensitivity in rheumatoid arthritis: a cross-sectional study
    Yvonne C Lee
    Division of Rheumatology, Immunology and Allergy, Brigham and Women s Hospital, 75 Francis Street, PBB B3, Boston, MA 02115, USA
    Arthritis Res Ther 11:R160. 2009
  5. pmc A prospective study of androgen levels, hormone-related genes and risk of rheumatoid arthritis
    Elizabeth W Karlson
    Division of Rheumatology, Immunology, and Allergy, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
    Arthritis Res Ther 11:R97. 2009
  6. pmc Genetic risk score predicting risk of rheumatoid arthritis phenotypes and age of symptom onset
    Lori B Chibnik
    Program in Translational NeuroPsychiatric Genomics, Department of Neurology, Brigham and Women s Hospital, Boston, Massachusetts, United States of America
    PLoS ONE 6:e24380. 2011
  7. pmc Gene-environment interaction between HLA-DRB1 shared epitope and heavy cigarette smoking in predicting incident rheumatoid arthritis
    E W Karlson
    Division of Rheumatology, Immunology, and Allergy, Brigham and Women s Hospital and Harvard Medical School, 75 Francis Street, Boston, Massachusetts 02115, USA
    Ann Rheum Dis 69:54-60. 2010
  8. doi request reprint Quantifying anti-cyclic citrullinated peptide titres: clinical utility and association with tobacco exposure in patients with rheumatoid arthritis
    D M Lee
    Department of Medicine, Division of Rheumatology, Immunology and Allergy, Brigham and Women s Hospital, Smith 552B, 1 Jimmy Fund Way, Boston, Massachusetts 02115, USA
    Ann Rheum Dis 68:201-8. 2009
  9. pmc Cumulative association of 22 genetic variants with seropositive rheumatoid arthritis risk
    Elizabeth W Karlson
    75 Francis Street, Boston, MA 02115, USA
    Ann Rheum Dis 69:1077-85. 2010
  10. pmc Associations between human leukocyte antigen, PTPN22, CTLA4 genotypes and rheumatoid arthritis phenotypes of autoantibody status, age at diagnosis and erosions in a large cohort study
    E W Karlson
    Division of Rheumatology, Allergy, and Immunology, Department of Medicine, Brigham and Women s Hospital, Boston, Massachusetts, USA
    Ann Rheum Dis 67:358-63. 2008

Detail Information

Publications26

  1. pmc Comparison of threshold cutpoints and continuous measures of anti-cyclic citrullinated peptide antibodies in predicting future rheumatoid arthritis
    Lori B Chibnik
    Division of Rheumatology, Immunology, and Allergy, Brigham and Women s Hospital, Harvard Medical School, 75 Francis St, Boston, MA 02115, USA
    J Rheumatol 36:706-11. 2009
    ..While the anti-CCP level is commonly dichotomized for clinical use, the best threshold for and utility of the titer as a continuous variable to predict development of RA are uncertain...
  2. pmc Identification and validation of lupus nephritis cases using administrative data
    L B Chibnik
    Division of Rheumatology, Immunology and Allergy, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
    Lupus 19:741-3. 2010
    ..This strategy may offer a sound method of identifying patients with lupus nephritis for health services research in addition to serving as a model for using claims data as a way to better understand rare diseases such as lupus...
  3. ncbi request reprint Dietary caffeine intake does not affect methotrexate efficacy in patients with rheumatoid arthritis
    Elizabeth Benito-Garcia
    Division of Rheumatology, Immunology and Allergy, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
    J Rheumatol 33:1275-81. 2006
    ..We investigated whether patients with RA taking MTX with a higher dietary caffeine intake have a worse clinical response to MTX than those with a lower intake...
  4. pmc The relationship between disease activity, sleep, psychiatric distress and pain sensitivity in rheumatoid arthritis: a cross-sectional study
    Yvonne C Lee
    Division of Rheumatology, Immunology and Allergy, Brigham and Women s Hospital, 75 Francis Street, PBB B3, Boston, MA 02115, USA
    Arthritis Res Ther 11:R160. 2009
    ..The etiology of RA pain is likely multifactorial, including both inflammatory and non-inflammatory components. In this study, we examine the association between disease activity, sleep, psychiatric distress and pain sensitivity in RA...
  5. pmc A prospective study of androgen levels, hormone-related genes and risk of rheumatoid arthritis
    Elizabeth W Karlson
    Division of Rheumatology, Immunology, and Allergy, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
    Arthritis Res Ther 11:R97. 2009
    ....
  6. pmc Genetic risk score predicting risk of rheumatoid arthritis phenotypes and age of symptom onset
    Lori B Chibnik
    Program in Translational NeuroPsychiatric Genomics, Department of Neurology, Brigham and Women s Hospital, Boston, Massachusetts, United States of America
    PLoS ONE 6:e24380. 2011
    ..Cumulative genetic profiles can help identify individuals at high-risk for developing RA. We examined the impact of 39 validated genetic risk alleles on the risk of RA phenotypes characterized by serologic and erosive status...
  7. pmc Gene-environment interaction between HLA-DRB1 shared epitope and heavy cigarette smoking in predicting incident rheumatoid arthritis
    E W Karlson
    Division of Rheumatology, Immunology, and Allergy, Brigham and Women s Hospital and Harvard Medical School, 75 Francis Street, Boston, Massachusetts 02115, USA
    Ann Rheum Dis 69:54-60. 2010
    ..To address the effect of dosage, a case-control study nested within two prospective cohorts to determine the interaction between heavy smoking and the HLA-SE was conducted...
  8. doi request reprint Quantifying anti-cyclic citrullinated peptide titres: clinical utility and association with tobacco exposure in patients with rheumatoid arthritis
    D M Lee
    Department of Medicine, Division of Rheumatology, Immunology and Allergy, Brigham and Women s Hospital, Smith 552B, 1 Jimmy Fund Way, Boston, Massachusetts 02115, USA
    Ann Rheum Dis 68:201-8. 2009
    ..To determine the significance of quantitative levels of antibodies to cyclic citrullinated peptides (anti-CCP) in a population of patients with rheumatoid arthritis (RA)...
  9. pmc Cumulative association of 22 genetic variants with seropositive rheumatoid arthritis risk
    Elizabeth W Karlson
    75 Francis Street, Boston, MA 02115, USA
    Ann Rheum Dis 69:1077-85. 2010
    ..This study examined whether a cumulative score based on 22 validated genetic risk alleles for seropositive RA would identify high-risk, asymptomatic individuals who might benefit from preventive interventions...
  10. pmc Associations between human leukocyte antigen, PTPN22, CTLA4 genotypes and rheumatoid arthritis phenotypes of autoantibody status, age at diagnosis and erosions in a large cohort study
    E W Karlson
    Division of Rheumatology, Allergy, and Immunology, Department of Medicine, Brigham and Women s Hospital, Boston, Massachusetts, USA
    Ann Rheum Dis 67:358-63. 2008
    ..HLA-DRB1 shared epitope (HLA-SE), PTPN22 and CTLA4 alleles are associated with cyclic citrullinated peptide (CCP) and rheumatoid arthritis (RA)...
  11. pmc Complications for racial and ethnic minority groups after total hip and knee replacement: a review of the literature
    Benedict U Nwachukwu
    Orthopedic and Arthritis Center for Outcomes Research, Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
    J Bone Joint Surg Am 92:338-45. 2010
    ..It has been shown that racial and ethnic minority groups underutilize these procedures; however, little information exists on postoperative outcomes for ethnic minorities...
  12. ncbi request reprint Occupational silica and solvent exposures and risk of systemic lupus erythematosus in urban women
    Axel Finckh
    Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
    Arthritis Rheum 54:3648-54. 2006
    ..To assess the risk of systemic lupus erythematosus (SLE) associated with occupational exposure to silica dust and organic solvents in an urban population...
  13. pmc A randomized controlled trial of an intervention to reduce low literacy barriers in inflammatory arthritis management
    Rima E Rudd
    Harvard School of Public Health, Department of Society, Human Development and Health, Boston, MA 02115, United States
    Patient Educ Couns 75:334-9. 2009
    ..Test the efficacy of educational interventions to reduce literacy barriers and enhance health outcomes among patients with inflammatory arthritis...
  14. pmc Integration of genetic risk factors into a clinical algorithm for multiple sclerosis susceptibility: a weighted genetic risk score
    Philip L De Jager
    Program in Translational NeuroPsychiatric Genomics, Department of Neurology, Brigham and Women s Hospital, Boston, MA 02115, USA
    Lancet Neurol 8:1111-9. 2009
    ..We investigated the usefulness of an aggregate measure of risk of MS that is based on genetic susceptibility loci. We also assessed the added effect of environmental risk factors that are associated with susceptibility for MS...
  15. pmc A controlled comparison of brachial artery flow mediated dilation (FMD) and digital pulse amplitude tonometry (PAT) in the assessment of endothelial function in systemic lupus erythematosus
    J Aizer
    Division of Rheumatology, Hospital for Special Surgery, Weill Cornell Medical College, New York, New York 10021, USA
    Lupus 18:235-42. 2009
    ..FMD did not correlate with PAT except in SLE cases with a history of Raynaud's. Correlation between FMD and PAT may be stronger in populations with greater variation in endothelial function and more cardiovascular risk factors...
  16. pmc Biomarkers of inflammation and development of rheumatoid arthritis in women from two prospective cohort studies
    Elizabeth W Karlson
    Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
    Arthritis Rheum 60:641-52. 2009
    ..To examine the association of biomarkers of inflammation with preclinical rheumatoid arthritis (RA)...
  17. ncbi request reprint Discordance between erythrocyte sedimentation rate and C-reactive protein measurements: clinical significance
    K H Costenbader
    Division of Rheumatology, Immunology, and Allergy, Section of Clinical Sciences, Brigham and Women s Hospital, Harvard Medical School, Boston, USA
    Clin Exp Rheumatol 25:746-9. 2007
    ..C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR) are common measures of systemic inflammation. Our goal was to identify clinical factors associated with CRP/ESR discordance...
  18. pmc Effect of interactions of glutathione S-transferase T1, M1, and P1 and HMOX1 gene promoter polymorphisms with heavy smoking on the risk of rheumatoid arthritis
    Brendan T Keenan
    Harvard Medical School and Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
    Arthritis Rheum 62:3196-210. 2010
    ..This study was undertaken to examine the impact of gene-smoking interactions on susceptibility to rheumatoid arthritis (RA)...
  19. pmc Location specific radiographic joint space width for osteoarthritis progression
    G Neumann
    Radiology, Brigham and Women s Hospital Harvard Medical School, Boston, MA 02115, USA
    Osteoarthritis Cartilage 17:761-5. 2009
    ..The study also investigated the most disease-responsive location for measuring medial compartment JSW...
  20. ncbi request reprint Alcohol consumption and the risk of bladder cancer in the Framingham Heart Study
    Luc Djousse
    Preventive Medicine and Epidemiology Section, Evans Department of Medicine, Boston University School of Medicine, Rm B 612, 715 Albany St, Boston, MA 02118, USA
    J Natl Cancer Inst 96:1397-400. 2004
    ..03), whereas wine (P(trend) =.7) and spirit (P(trend) =.2) consumption were not. Our data suggest that total and beverage-specific alcohol consumption are not associated with an increased risk of bladder cancer...
  21. ncbi request reprint Development of a preliminary index that predicts adverse events after total knee replacement
    Daniel H Solomon
    Division of Pharmacoepidemiology, Brigham and Women s Hospital, Boston, Massachusetts 02120, USA
    Arthritis Rheum 54:1536-42. 2006
    ....
  22. pmc Hand bone mineral density is associated with both total hip and lumbar spine bone mineral density in post-menopausal women with RA
    Sonali P Desai
    Brigham and Women s Hospital, PBB B3, Boston, MA 02115, USA
    Rheumatology (Oxford) 49:513-9. 2010
    ..RA is associated with localized bone loss in the hands, as well as generalized osteoporosis. We evaluated the relationship between hand digital X-ray radiogrammetry BMD (DXR-BMD) and total hip and lumbar spine BMD...
  23. ncbi request reprint Pattern of infliximab utilization in rheumatoid arthritis patients at an academic medical center
    Sandeep K Agarwal
    Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
    Arthritis Rheum 53:872-8. 2005
    ..To investigate the pattern of use of infliximab with an emphasis on treatment escalation and the durability of infliximab use in the management of rheumatoid arthritis (RA) in an academic setting...
  24. pmc Intermediate phenotypes identify divergent pathways to Alzheimer's disease
    Joshua M Shulman
    Program in Translational NeuroPsychiatric Genomics, Department of Neurology, Brigham and Women s Hospital, Boston, Massachusetts, USA
    PLoS ONE 5:e11244. 2010
    ..However, little is known of the role of these candidate genes in influencing intermediate phenotypes associated with a diagnosis of AD, including cognitive decline or AD neuropathologic burden...
  25. ncbi request reprint Cutaneous changes of nephrogenic systemic fibrosis: predictor of early mortality and association with gadolinium exposure
    Derrick J Todd
    Massachusetts General Hospital, Harvard Medical School, and Brigham and Women s Hospital, Boston, Massachusetts 02114, USA
    Arthritis Rheum 56:3433-41. 2007
    ..Little is known about its prevalence or etiology. The aim of this study was to establish the prevalence of NSF and associated risk factors..
  26. ncbi request reprint A pravastatin dose-escalation study in systemic lupus erythematosus
    Karen H Costenbader
    Division of Rheumatology, Immunology, and Allergy, Section of Clinical Sciences, Brigham and Women s Hospital, Harvard Medical School, 75 Francis St, Boston, MA 02115, USA
    Rheumatol Int 27:1071-7. 2007
    ..Pravastatin reduced LDL and total cholesterol levels approximately the same degree observed in normal individuals, but the effect appeared blunted in those on modest doses of glucocorticoids and those with higher BMI...