Franck Chiappini

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. ncbi Relationship between polymerase gamma (POLG) polymorphisms and antiretroviral therapy-induced lipodystrophy in HIV-1 infected patients: a case-control study
    Franck Chiappini
    AP HP, Hopital Paul Brousse, Service de Biochimie et de Biologie Moléculaire, Université Paris 11, 12, avenue Paul Vaillant Couturier, Villejuif Cedex, France
    Curr HIV Res 7:244-53. 2009
  2. ncbi Prospective evaluation of blood concentration of mitochondrial DNA as a marker of toxicity in 157 consecutively recruited untreated or HAART-treated HIV-positive patients
    Franck Chiappini
    Service de Biochimie et de Biologie Moléculaire INSERM 602, Hopital Paul Brousse, 12 avenue Paul Vaillant Couturier, 94800 Villejuif, France
    Lab Invest 84:908-14. 2004
  3. ncbi Exploration of global gene expression in human liver steatosis by high-density oligonucleotide microarray
    Franck Chiappini
    INSERM 602, Service de Biochimie et Biologie Moléculaire, Hôpital Universitaire Paul Brousse, Universite Paris XI, Villejuif Cedex, France
    Lab Invest 86:154-65. 2006
  4. doi Generation and modulation of hepatocellular carcinoma circulating cells: a new experimental model
    Olivier Scatton
    Service de Biochimie et de Biologie Moléculaire, AP HP, Hopital Paul Brousse, Villejuif, France
    J Surg Res 150:183-9. 2008
  5. ncbi Microsatellite instability mutator phenotype in hepatocellular carcinoma in non-alcoholic and non-virally infected normal livers
    Franck Chiappini
    Service de Biochimie et Biologie Moléculaire, Hopital Paul Brousse, Assistance Publique Hopitaux de Paris, France
    Carcinogenesis 25:541-7. 2004

Collaborators

Detail Information

Publications5

  1. ncbi Relationship between polymerase gamma (POLG) polymorphisms and antiretroviral therapy-induced lipodystrophy in HIV-1 infected patients: a case-control study
    Franck Chiappini
    AP HP, Hopital Paul Brousse, Service de Biochimie et de Biologie Moléculaire, Université Paris 11, 12, avenue Paul Vaillant Couturier, Villejuif Cedex, France
    Curr HIV Res 7:244-53. 2009
    ..These could be due to decreased content of mtDNA in PBMC in these patients. Therefore, the toxicity of NRTIs leading to lipodystrophy in some HIV-1 infected patients could be explained in part by the occurrence of POLG polymorphisms...
  2. ncbi Prospective evaluation of blood concentration of mitochondrial DNA as a marker of toxicity in 157 consecutively recruited untreated or HAART-treated HIV-positive patients
    Franck Chiappini
    Service de Biochimie et de Biologie Moléculaire INSERM 602, Hopital Paul Brousse, 12 avenue Paul Vaillant Couturier, 94800 Villejuif, France
    Lab Invest 84:908-14. 2004
    ..Thus, the mtDNA to nDNA ratio in leukocytes does not seem to be an accurate marker of mild and/or long-term mitochondrial toxicity...
  3. ncbi Exploration of global gene expression in human liver steatosis by high-density oligonucleotide microarray
    Franck Chiappini
    INSERM 602, Service de Biochimie et Biologie Moléculaire, Hôpital Universitaire Paul Brousse, Universite Paris XI, Villejuif Cedex, France
    Lab Invest 86:154-65. 2006
    ..Activation of inflammatory pathways is present at a very early stage of steatosis, even if no morphological sign of inflammation is observed...
  4. doi Generation and modulation of hepatocellular carcinoma circulating cells: a new experimental model
    Olivier Scatton
    Service de Biochimie et de Biologie Moléculaire, AP HP, Hopital Paul Brousse, Villejuif, France
    J Surg Res 150:183-9. 2008
    ..To establish a new experimental model of human hepatocellular carcinoma by orthotopic implantation of tumoral cells with its subsequent removal, to generate and modulate circulating tumoral cells...
  5. ncbi Microsatellite instability mutator phenotype in hepatocellular carcinoma in non-alcoholic and non-virally infected normal livers
    Franck Chiappini
    Service de Biochimie et Biologie Moléculaire, Hopital Paul Brousse, Assistance Publique Hopitaux de Paris, France
    Carcinogenesis 25:541-7. 2004
    ..Thus, we have found a small subgroup of HCC tumors which can be considered as a new clinical/histological entity...