BOBBY CHERAYIL

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. ncbi Salmonella enterica serovar typhimurium-dependent regulation of inducible nitric oxide synthase expression in macrophages by invasins SipB, SipC, and SipD and effector SopE2
    B J Cherayil
    Mucosal Immunology Laboratory, Combined Program in Pediatric Gastroenterology and Nutrition, Massachusetts General Hospital, Charlestown, Massachusetts 02129, USA
    Infect Immun 68:5567-74. 2000
  2. ncbi Inducible nitric oxide synthase and Salmonella infection
    B J Cherayil
    Mucosal Immunology Laboratory, Combined Program in Pediatric Gastroenterology and Nutrition, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02129, USA
    Microbes Infect 3:771-6. 2001
  3. ncbi Indoleamine 2,3-dioxygenase in intestinal immunity and inflammation
    Bobby J Cherayil
    Pediatric Gastroenterology Unit, Massachusetts General Hospital, Charlestown, MA 02129, USA
    Inflamm Bowel Dis 15:1391-6. 2009
  4. ncbi Iron and immunity: immunological consequences of iron deficiency and overload
    Bobby J Cherayil
    Department of Pediatrics, Mucosal Immunology Laboratory, Massachusetts General Hospital, Harvard Medical School, Building 114, 16th Street, Charlestown, Boston, MA 02129, USA
    Arch Immunol Ther Exp (Warsz) 58:407-15. 2010
  5. ncbi The role of iron in the immune response to bacterial infection
    Bobby J Cherayil
    Mucosal Immunology Laboratory, MassGeneral Hospital for Children, Charlestown, MA 02129, USA
    Immunol Res 50:1-9. 2011
  6. ncbi Iron and intestinal immunity
    Bobby J Cherayil
    Mucosal Immunology Laboratory, MassGeneral Hospital for Children, Charlestown, Massachusetts, USA
    Curr Opin Gastroenterol 27:523-8. 2011
  7. ncbi Mac-2-binding glycoproteins. Putative ligands for a cytosolic beta-galactoside lectin
    I Rosenberg
    Molecular Immunology Laboratory, Massachusetts General Hospital, Boston
    J Biol Chem 266:18731-6. 1991
  8. ncbi Molecular cloning of a human macrophage lectin specific for galactose
    B J Cherayil
    Molecular Immunology Laboratory, Massachusetts General Hospital, Boston
    Proc Natl Acad Sci U S A 87:7324-8. 1990

Research Grants

  1. Induction of Macrophage iNOS by Salmonella
    BOBBY CHERAYIL; Fiscal Year: 2006
  2. Mammalian metal transporters & Salmonella infection
    BOBBY CHERAYIL; Fiscal Year: 2006

Collaborators

Detail Information

Publications8

  1. ncbi Salmonella enterica serovar typhimurium-dependent regulation of inducible nitric oxide synthase expression in macrophages by invasins SipB, SipC, and SipD and effector SopE2
    B J Cherayil
    Mucosal Immunology Laboratory, Combined Program in Pediatric Gastroenterology and Nutrition, Massachusetts General Hospital, Charlestown, Massachusetts 02129, USA
    Infect Immun 68:5567-74. 2000
    ..These observations suggest that iNOS expression is regulated by signals activated by SopE2 (and possibly SopE) and that the role of SipB, SipC, and SipD in this process is to facilitate translocation of the relevant effector...
  2. ncbi Inducible nitric oxide synthase and Salmonella infection
    B J Cherayil
    Mucosal Immunology Laboratory, Combined Program in Pediatric Gastroenterology and Nutrition, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02129, USA
    Microbes Infect 3:771-6. 2001
    ..This review summarizes current knowledge of the molecular mechanisms involved in the induction process, and discusses the functional significance of nitric oxide production in the context of host defense against Salmonella...
  3. ncbi Indoleamine 2,3-dioxygenase in intestinal immunity and inflammation
    Bobby J Cherayil
    Pediatric Gastroenterology Unit, Massachusetts General Hospital, Charlestown, MA 02129, USA
    Inflamm Bowel Dis 15:1391-6. 2009
    ..However, its precise role in intestinal immunity is not well understood. This review will summarize the current state of knowledge about IDO function, particularly as it pertains to inflammatory responses in the gut...
  4. ncbi Iron and immunity: immunological consequences of iron deficiency and overload
    Bobby J Cherayil
    Department of Pediatrics, Mucosal Immunology Laboratory, Massachusetts General Hospital, Harvard Medical School, Building 114, 16th Street, Charlestown, Boston, MA 02129, USA
    Arch Immunol Ther Exp (Warsz) 58:407-15. 2010
    ..This article will review what is currently known about how disturbances of iron metabolism can affect immunity and how activation of the immune system can lead to alterations in iron balance...
  5. ncbi The role of iron in the immune response to bacterial infection
    Bobby J Cherayil
    Mucosal Immunology Laboratory, MassGeneral Hospital for Children, Charlestown, MA 02129, USA
    Immunol Res 50:1-9. 2011
    ..I will review here what we have learned about the interactions between iron and immunity and discuss the implications of the information that we have acquired...
  6. ncbi Iron and intestinal immunity
    Bobby J Cherayil
    Mucosal Immunology Laboratory, MassGeneral Hospital for Children, Charlestown, Massachusetts, USA
    Curr Opin Gastroenterol 27:523-8. 2011
    ..We will review this new information in the context of the gastrointestinal tract...
  7. ncbi Mac-2-binding glycoproteins. Putative ligands for a cytosolic beta-galactoside lectin
    I Rosenberg
    Molecular Immunology Laboratory, Massachusetts General Hospital, Boston
    J Biol Chem 266:18731-6. 1991
    ..N-terminal sequence analysis of M2BP-2 suggests that these glycoproteins represent a unique subset of candidate ligands for this mammalian beta-galactoside lectin...
  8. ncbi Molecular cloning of a human macrophage lectin specific for galactose
    B J Cherayil
    Molecular Immunology Laboratory, Massachusetts General Hospital, Boston
    Proc Natl Acad Sci U S A 87:7324-8. 1990
    ..These findings are discussed in the context of the potential functions of hMac-2...

Research Grants6

  1. Induction of Macrophage iNOS by Salmonella
    BOBBY CHERAYIL; Fiscal Year: 2006
    ..The results of these studies will shed light on a novel function of SopE and SopE2 and will also improve understanding of the mechanisms that regulate iNOS expression. ..
  2. Mammalian metal transporters & Salmonella infection
    BOBBY CHERAYIL; Fiscal Year: 2006
    ..These studies will identify new aspects of the Salmonella-host cell interaction, shed light on the role of mammalian metal transporters in Salmonella infection, and suggest novel approaches to treating salmonellosis. ..