Yen Ching Chen

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. ncbi Family history of prostate and breast cancer and the risk of prostate cancer in the PSA era
    Yen Ching Chen
    Department of Medicine, Channing Laboratory, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
    Prostate 68:1582-91. 2008
  2. ncbi Interaction between environmental tobacco smoke and arsenic methylation ability on the risk of bladder cancer
    Yen Ching Chen
    Department of Medicine, Channing Laboratory, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
    Cancer Causes Control 16:75-81. 2005
  3. ncbi Polymorphisms in GSTT1 and p53 and urinary transitional cell carcinoma in south-western Taiwan: a preliminary study
    Y C Chen
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, MA 02115, Boston, USA
    Biomarkers 9:386-94. 2004
  4. ncbi Sequence variants of estrogen receptor beta and risk of prostate cancer in the National Cancer Institute Breast and Prostate Cancer Cohort Consortium
    Yen Ching Chen
    Channing Laboratory, 181 Longwood Avenue, Boston, MA 02115, USA
    Cancer Epidemiol Biomarkers Prev 16:1973-81. 2007
  5. ncbi Association between Toll-like receptor gene cluster (TLR6, TLR1, and TLR10) and prostate cancer
    Yen Ching Chen
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, 181 Longwood Avenue, Boston, MA 02115, USA
    Cancer Epidemiol Biomarkers Prev 16:1982-9. 2007
  6. ncbi Sequence variants of elaC homolog 2 (Escherichia coli) (ELAC2) gene and susceptibility to prostate cancer in the Health Professionals Follow-Up Study
    Yen Ching Chen
    Department of Medicine, Channing Laboratory, Brigham and Women s Hospital, Harvard Medical School, 181 Longwood Avenue, Boston, MA 02115, USA
    Carcinogenesis 29:999-1004. 2008
  7. ncbi Association between genetic polymorphisms of macrophage scavenger receptor 1 gene and risk of prostate cancer in the health professionals follow-up study
    Yen Ching Chen
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    Cancer Epidemiol Biomarkers Prev 17:1001-3. 2008
  8. ncbi Sequence variants of Toll-like receptor 4 and susceptibility to prostate cancer
    Yen Ching Chen
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
    Cancer Res 65:11771-8. 2005
  9. ncbi Genetic polymorphism in p53 codon 72 and skin cancer in southwestern Taiwan
    Yen Ching Chen
    Occupational Health Program, Department of Environmental Health, Harvard School of Public Health, Boston, Massachusetts, USA
    J Environ Sci Health A Tox Hazard Subst Environ Eng 38:201-11. 2003
  10. ncbi Occurrence and treatment of suspected pneumonia in long-term care residents dying with advanced dementia
    Jen Hau Chen
    Hebrew SeniorLife, Research and Training Institute and Department of Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02131, USA
    J Am Geriatr Soc 54:290-5. 2006

Detail Information

Publications18

  1. ncbi Family history of prostate and breast cancer and the risk of prostate cancer in the PSA era
    Yen Ching Chen
    Department of Medicine, Channing Laboratory, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
    Prostate 68:1582-91. 2008
    ..A family history of prostate cancer (PCa) or breast cancer (BCa) has been associated with the risk of PCa, but the risks were inconsistent in terms of the affected family members, and data in the PSA era are limited...
  2. ncbi Interaction between environmental tobacco smoke and arsenic methylation ability on the risk of bladder cancer
    Yen Ching Chen
    Department of Medicine, Channing Laboratory, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
    Cancer Causes Control 16:75-81. 2005
    ..We hypothesize that interaction between ETS and the ability to methylate arsenic, a detoxification pathway, modifies the risk of bladder cancer...
  3. ncbi Polymorphisms in GSTT1 and p53 and urinary transitional cell carcinoma in south-western Taiwan: a preliminary study
    Y C Chen
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, MA 02115, Boston, USA
    Biomarkers 9:386-94. 2004
    ..However, the results were not statistically significant and larger confirmatory studies are needed to clarify the role of candidate gene polymorphisms and bladder cancer risk in arsenic exposed populations...
  4. ncbi Sequence variants of estrogen receptor beta and risk of prostate cancer in the National Cancer Institute Breast and Prostate Cancer Cohort Consortium
    Yen Ching Chen
    Channing Laboratory, 181 Longwood Avenue, Boston, MA 02115, USA
    Cancer Epidemiol Biomarkers Prev 16:1973-81. 2007
    ..Estrogen receptor beta (ESR2) may play a role in modulating prostate carcinogenesis through the regulation of genes related to cell proliferation and apoptosis...
  5. ncbi Association between Toll-like receptor gene cluster (TLR6, TLR1, and TLR10) and prostate cancer
    Yen Ching Chen
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, 181 Longwood Avenue, Boston, MA 02115, USA
    Cancer Epidemiol Biomarkers Prev 16:1982-9. 2007
    ..We assessed if genetic polymorphisms of this gene cluster were associated with the risk of prostate cancer in a U.S. population...
  6. ncbi Sequence variants of elaC homolog 2 (Escherichia coli) (ELAC2) gene and susceptibility to prostate cancer in the Health Professionals Follow-Up Study
    Yen Ching Chen
    Department of Medicine, Channing Laboratory, Brigham and Women s Hospital, Harvard Medical School, 181 Longwood Avenue, Boston, MA 02115, USA
    Carcinogenesis 29:999-1004. 2008
    ..43, snp3: OR = 0.69, hap1: OR = 1.47, hap2: OR = 0.72, hap4: OR = 1.51; global P-value for all common haplotypes = 0.11). Common SNPs and haplotypes of ELAC2 were associated with risk of aggressive prostate cancer...
  7. ncbi Association between genetic polymorphisms of macrophage scavenger receptor 1 gene and risk of prostate cancer in the health professionals follow-up study
    Yen Ching Chen
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    Cancer Epidemiol Biomarkers Prev 17:1001-3. 2008
    ..Association studies assessing the relationship between sequence variants of MSR1 and prostate cancer are inconsistent. We hypothesized that sequence variants of MSR1 were associated with prostate cancer risk...
  8. ncbi Sequence variants of Toll-like receptor 4 and susceptibility to prostate cancer
    Yen Ching Chen
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
    Cancer Res 65:11771-8. 2005
    ..02). Two common haplotypes were statistically significantly associated with altered risk of prostate cancer. Inherited polymorphisms of the innate immune gene TLR4 are associated with risk of prostate cancer...
  9. ncbi Genetic polymorphism in p53 codon 72 and skin cancer in southwestern Taiwan
    Yen Ching Chen
    Occupational Health Program, Department of Environmental Health, Harvard School of Public Health, Boston, Massachusetts, USA
    J Environ Sci Health A Tox Hazard Subst Environ Eng 38:201-11. 2003
    ..The risk of skin cancer is increased in individuals with the Pro/Pro genotype. Larger, confirmatory studies are needed to clarify the role of constitutional polymorphisms in p53 and skin cancer risk...
  10. ncbi Occurrence and treatment of suspected pneumonia in long-term care residents dying with advanced dementia
    Jen Hau Chen
    Hebrew SeniorLife, Research and Training Institute and Department of Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02131, USA
    J Am Geriatr Soc 54:290-5. 2006
    ..To describe the occurrence and management of suspected pneumonia in end-stage dementia and to identify factors associated with aggressiveness of antibiotic treatment...
  11. ncbi Arsenic methylation, GSTT1, GSTM1, GSTP1 polymorphisms, and skin lesions
    Kathleen M McCarty
    Yale University School of Medicine, Epidemiology and Public Health, Division of Environmental Health Sciences, New Haven, Connecticut 06520, USA
    Environ Health Perspect 115:341-5. 2007
    ..We investigated whether primary and secondary arsenic methylation ratios were associated with skin lesions and whether GSTT1, GSTP1, and GSTM1 polymorphisms modify these relationships...
  12. ncbi Genetic variation in the HSD17B1 gene and risk of prostate cancer
    Peter Kraft
    Program in Molecular and Genetic Epidemiology, Harvard School of Public Health, Boston, Massachusetts, United States of America
    PLoS Genet 1:e68. 2005
    ..These results suggest that the germline variants in HSD17B1 characterized by these htSNPs do not substantially influence the risk of prostate cancer in U.S. and European whites...
  13. ncbi Sex steroid hormones and the androgen receptor gene CAG repeat and subsequent risk of prostate cancer in the prostate-specific antigen era
    Elizabeth A Platz
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Room E6138, 615 North Wolfe Street, Baltimore, MD 21205, USA
    Cancer Epidemiol Biomarkers Prev 14:1262-9. 2005
    ..We investigated plasma levels of sex steroid hormones and length of the androgen receptor gene CAG repeat in relation to incident prostate cancer diagnosed in the prostate-specific antigen (PSA) era...
  14. ncbi Molecular epidemiology of cancer
    Yen-Ching Chen
    Brigham and Women's Hospital, Department of Medicine, Harvard Medical School, Boston, MA, USA
    CA Cancer J Clin 55:45-54; quiz 57. 2005
    ..Examples will be given of how use of molecular techniques is informative in epidemiological studies of cancer and is predicted to lead to improvements in cancer incidence, early detection, and mortality...
  15. ncbi Lung adenocarcinoma and human papillomavirus infection
    Yen-Ching Chen
    Channing Laboratory, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA
    Cancer 101:1428-36. 2004
    ..Further epidemiologic and pathologic investigations will be necessary to establish a causal relation...
  16. ncbi Arsenic methylation and bladder cancer risk in Taiwan
    Yen-Ching Chen
    Occupational Health Program, Department of Environmental Health, Harvard School of Public Health, Boston, MA 02115, USA
    Cancer Causes Control 14:303-10. 2003
    ..31, 95% CI 0.84-12.97) had a higher risk of bladder cancer when compared to women. CONCLUSIONS: Subjects with low SMI have a substantially increased risk of bladder cancer, especially when combined with high CAE levels...
  17. ncbi Arsenic methylation and skin cancer risk in southwestern Taiwan
    Yen-Ching Chen
    Occupational Health Program, Department of Environmental Health, Harvard School of Public Health, 665 Huntington Avenue, Boston, MA 02115, USA
    J Occup Environ Med 45:241-8. 2003
    ..46-11.22) when compared to women. Subjects with low SMI and high CAE have a substantially increased risk of skin cancer. Males in all strata of arsenic exposure and methylation ability had a higher risk of skin cancer than women...
  18. ncbi Stability of arsenic species and insoluble arsenic in human urine
    Yen-Ching Chen
    Occupational Health Program, Department of Environmental Health, Harvard School of Public Health, Boston, Massachusetts 02115, USA
    Cancer Epidemiol Biomarkers Prev 11:1427-33. 2002
    ....